ATE348631T1 - Verwendung von plasminogen zur heilung von zerbrochenen trommelfellen - Google Patents

Verwendung von plasminogen zur heilung von zerbrochenen trommelfellen

Info

Publication number
ATE348631T1
ATE348631T1 AT02797695T AT02797695T ATE348631T1 AT E348631 T1 ATE348631 T1 AT E348631T1 AT 02797695 T AT02797695 T AT 02797695T AT 02797695 T AT02797695 T AT 02797695T AT E348631 T1 ATE348631 T1 AT E348631T1
Authority
AT
Austria
Prior art keywords
plasminogen
eartums
healing
relates
tympanic membrane
Prior art date
Application number
AT02797695T
Other languages
English (en)
Inventor
Tor Ny
Jinan Li
Sten Hellstrom
Per-Olof Eriksson
Original Assignee
Omnio Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omnio Ab filed Critical Omnio Ab
Application granted granted Critical
Publication of ATE348631T1 publication Critical patent/ATE348631T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/484—Plasmin (3.4.21.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Manufacture Of Motors, Generators (AREA)
AT02797695T 2001-09-06 2002-09-06 Verwendung von plasminogen zur heilung von zerbrochenen trommelfellen ATE348631T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31764301P 2001-09-06 2001-09-06

Publications (1)

Publication Number Publication Date
ATE348631T1 true ATE348631T1 (de) 2007-01-15

Family

ID=23234611

Family Applications (2)

Application Number Title Priority Date Filing Date
AT02797695T ATE348631T1 (de) 2001-09-06 2002-09-06 Verwendung von plasminogen zur heilung von zerbrochenen trommelfellen
AT06126236T ATE552842T1 (de) 2001-09-06 2002-09-06 Verwendung von plasminogen zur wundheilung

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT06126236T ATE552842T1 (de) 2001-09-06 2002-09-06 Verwendung von plasminogen zur wundheilung

Country Status (9)

Country Link
US (3) US7067492B2 (de)
EP (2) EP1427440B1 (de)
CN (2) CN1961958B (de)
AT (2) ATE348631T1 (de)
AU (1) AU2002361878A1 (de)
DE (1) DE60216939T2 (de)
DK (2) DK1427440T3 (de)
ES (2) ES2279001T3 (de)
WO (1) WO2003020297A2 (de)

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US7067492B2 (en) * 2001-09-06 2006-06-27 Omnio Ab Method of promoting healing of a tympanic membrane perforation
AU2006265601A1 (en) * 2005-06-30 2007-01-11 Anthrogenesis Corporation Repair of tympanic membrane using placenta derived collagen biofabric
EP2207035B1 (de) * 2006-03-14 2013-10-16 Oregon Health and Science University Methoden zur Detektion einer Mycobakterium tuberculosis Infektion
WO2008021391A1 (en) 2006-08-15 2008-02-21 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
WO2008026999A2 (en) 2006-08-28 2008-03-06 Omnio Healer Ab Candidates against infection
WO2008027000A2 (en) * 2006-08-28 2008-03-06 Omnio Healer Ab Novel drug target of preventing and treating periodontal disease, improving healing of periodontal wounds and promoting oral health
US8071135B2 (en) 2006-10-04 2011-12-06 Anthrogenesis Corporation Placental tissue compositions
AU2007318210B2 (en) 2006-10-06 2014-02-20 Celularity Inc. Native (telopeptide) placental collagen compositions
EP2152359A2 (de) 2007-05-25 2010-02-17 Compex Medical S.A. Elektrodenset für wundheilung
GB2450747A (en) * 2007-07-06 2009-01-07 Univ Sheffield Treatment of sensorineural hearing loss
WO2009093970A1 (en) * 2008-01-22 2009-07-30 Omnio Healer Ab Method of improving wound healing
RU2432397C2 (ru) * 2009-11-24 2011-10-27 Федеральное государственное учреждение "Российский кардиологический научно-производственный комплекс" Министерства здравоохранения и социального развития Российской Федерации (ФГУ "РКНПК" Минздравсоцразвития России) РЕКОМБИНАНТНЫЙ ПОЛИПЕПТИД СО СВОЙСТВАМИ ПЛАЗМИНОГЕНА ЧЕЛОВЕКА ПРЕВРАЩАТЬСЯ ПРИ АКТИВАЦИИ В ПЛАЗМИН, КОТОРЫЙ КАТАЛИЗИРУЕТ РАСЩЕПЛЕНИЕ ФИБРИНА, ФРАГМЕНТ ДНК, КОДИРУЮЩИЙ ПОЛИПЕПТИД, РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК ДЛЯ ЭКСПРЕССИИ ПОЛИПЕПТИДА И ТРАНСФОРМИРОВАННАЯ КЛЕТКА Escherichia coli - ПРОДУЦЕНТ ПОЛИПЕПТИДА
RU2432396C2 (ru) * 2009-11-24 2011-10-27 Федеральное государственное учреждение "Российский кардиологический научно-производственный комплекс" Министерства здравоохранения и социального развития Российской Федерации (ФГУ "РКНПК" Минздравсоцразвития России) РЕКОМБИНАНТНЫЙ ПОЛИПЕПТИД СО СВОЙСТВАМИ ПЛАЗМИНОГЕНА ЧЕЛОВЕКА ПРЕВРАЩАТЬСЯ ПРИ АКТИВАЦИИ В ПЛАЗМИН, КОТОРЫЙ КАТАЛИЗИРУЕТ РАСЩЕПЛЕНИЕ ФИБРИНА, ФРАГМЕНТ ДНК, КОДИРУЮЩИЙ ПОЛИПЕПТИД, РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК ДЛЯ ЭКСПРЕССИИ ПОЛИПЕПТИДА И ТРАНСФОРМИРОВАННАЯ КЛЕТКА Escherichia coli - ПРОДУЦЕНТ ПОЛИПЕПТИДА
PL2996709T3 (pl) 2013-05-15 2021-02-08 The Board Of Trustees Of The Leland Stanford Junior University Modulacja aktywności nabłonkowego czynnika wzrostu wiążącego heparynę do gojenia błony bębenkowej
TWI801331B (zh) * 2015-11-03 2023-05-11 美商波麥堤克生物治療股份有限公司 纖維蛋白溶酶原缺乏症之纖維蛋白溶酶原替代療法
TW201722464A (zh) * 2015-11-10 2017-07-01 波麥堤克生化科學有限公司 用於傷口癒合之纖維蛋白溶酶原給藥方案
TWI624267B (zh) * 2015-12-18 2018-05-21 Talengen Institute Of Life Sciences Co Ltd 纖溶酶原在製備預防或治療糖尿病性視網膜病變的藥劑上的用途及包括纖溶酶原用於預防或治療糖尿病性視網膜病變之藥劑
JP6793748B2 (ja) 2015-12-18 2020-12-02 タレンゲン インターナショナル リミテッドＴａｌｅｎｇｅｎ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｌｉｍｉｔｅｄ 放射性および化学的損傷を予防及び治療するための方法
US11338022B2 (en) 2015-12-18 2022-05-24 Talengen International Limited Method for preventing and treating angiocardiopathy
CN108778307A (zh) 2015-12-18 2018-11-09 泰伦基国际有限公司 一种预防和治疗糖尿病肾病的方法
TWI653981B (zh) * 2015-12-18 2019-03-21 深圳瑞健生命科學硏究院有限公司 Use of plasminogen for the preparation of a medicament for preventing or treating a condition associated with diabetic nerve injury
JP6876066B2 (ja) 2015-12-18 2021-05-26 タレンゲン インターナショナル リミテッドＴａｌｅｎｇｅｎ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｌｉｍｉｔｅｄ 子宮膣部びらんを予防及び治療するための方法
TWI674903B (zh) * 2016-09-26 2019-10-21 國立陽明大學 製備改良豬血漿纖連蛋白以增強傷口癒合之應用
US11129880B2 (en) 2016-12-15 2021-09-28 Talengen International Limited Method for promoting insulin secretion
EP3556385A4 (de) * 2016-12-15 2020-12-30 Talengen International Limited Verfahren zur verringerung von herzerkrankungen
CN108210899A (zh) * 2016-12-15 2018-06-29 深圳瑞健生命科学研究院有限公司 预防和治疗组织器官纤维化的药物及其用途
US11219669B2 (en) 2016-12-15 2022-01-11 Talengen International Limited Method for preventing and treating liver fibrosis
TW201822805A (zh) * 2016-12-15 2018-07-01 深圳瑞健生命科學硏究院有限公司 一種預防和治療脂肪異常沉積導致的組織損傷的方法
TW201829448A (zh) 2016-12-15 2018-08-16 大陸商深圳瑞健生命科學硏究院有限公司 纖溶酶原在製備預防或治療肥胖症及疾病倂發的肥胖的藥物中的用途
CN108210911A (zh) * 2016-12-15 2018-06-29 深圳瑞健生命科学研究院有限公司 一种促进胰岛素分泌的方法
US11938172B2 (en) 2017-06-19 2024-03-26 Talengen International Limited Method for regulating and controlling GLP-1/GLP-1R and drug
AR124640A1 (es) * 2020-11-25 2023-04-19 Grifols Worldwide Operations Ltd Cicatrización de heridas

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990013640A1 (en) * 1989-05-01 1990-11-15 The University Of Notre Dame Du Lac Methods and materials for expression of human plasminogen in a eukaryotic cell system
US6559119B1 (en) * 1990-11-27 2003-05-06 Loyola University Of Chicago Method of preparing a tissue sealant-treated biomedical material
US6197325B1 (en) * 1990-11-27 2001-03-06 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
ATE226089T1 (de) 1995-01-27 2002-11-15 Tno Verwendung einer zubereitung enthaltend einen plasminogen-aktivator für die verbesserung der wundheilung
CA2224253A1 (en) 1995-06-09 1996-12-27 Martin J. Macphee Chitin hydrogels, methods of their production and use
US6043407A (en) 1997-07-29 2000-03-28 Warner-Lambert Company Debridement pad
JP2002531385A (ja) * 1998-11-25 2002-09-24 ブリストル−マイヤーズ スクイブ カンパニー アンジオスタチンおよびプラスミノゲンのクリングル５領域を含む組成物およびその使用方法
WO2000061179A1 (en) * 1999-04-14 2000-10-19 Karolinska Innovations Ab Kringle domains of plasminogen, capable of modulating angiogenesis in vivo
US7067492B2 (en) 2001-09-06 2006-06-27 Omnio Ab Method of promoting healing of a tympanic membrane perforation
US7202066B2 (en) * 2002-01-29 2007-04-10 Carrington Laboratories, Inc. Combination of a growth factor and a protease enzyme

Also Published As

Publication number Publication date
EP1790354A3 (de) 2007-10-24
US20070041962A1 (en) 2007-02-22
US7067492B2 (en) 2006-06-27
EP1427440B1 (de) 2006-12-20
EP1427440A2 (de) 2004-06-16
ES2279001T3 (es) 2007-08-16
DK1427440T3 (da) 2007-04-30
DK1790354T3 (da) 2012-07-23
EP1790354B1 (de) 2012-04-11
US20080090751A1 (en) 2008-04-17
CN1961958B (zh) 2011-05-18
US8679482B2 (en) 2014-03-25
ES2387797T3 (es) 2012-10-01
WO2003020297A3 (en) 2003-10-09
WO2003020297A2 (en) 2003-03-13
ATE552842T1 (de) 2012-04-15
DE60216939D1 (de) 2007-02-01
DE60216939T2 (de) 2007-10-04
EP1790354A2 (de) 2007-05-30
AU2002361878A1 (en) 2003-03-18
US8637010B2 (en) 2014-01-28
WO2003020297A8 (en) 2004-07-08
CN1961958A (zh) 2007-05-16
CN1289145C (zh) 2006-12-13
US20030147879A1 (en) 2003-08-07
CN1585649A (zh) 2005-02-23

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