ATE552842T1 - Verwendung von plasminogen zur wundheilung - Google Patents

Verwendung von plasminogen zur wundheilung

Info

Publication number
ATE552842T1
ATE552842T1 AT06126236T AT06126236T ATE552842T1 AT E552842 T1 ATE552842 T1 AT E552842T1 AT 06126236 T AT06126236 T AT 06126236T AT 06126236 T AT06126236 T AT 06126236T AT E552842 T1 ATE552842 T1 AT E552842T1
Authority
AT
Austria
Prior art keywords
wound healing
plasminogen
healing
relates
tympanic membrane
Prior art date
Application number
AT06126236T
Other languages
English (en)
Inventor
Tor Ny
Jinan Li
Sten Hellstroem
Per-Olof Eriksson
Original Assignee
Omnio Healer Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omnio Healer Ab filed Critical Omnio Healer Ab
Application granted granted Critical
Publication of ATE552842T1 publication Critical patent/ATE552842T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/484—Plasmin (3.4.21.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Manufacture Of Motors, Generators (AREA)
  • Enzymes And Modification Thereof (AREA)
AT06126236T 2001-09-06 2002-09-06 Verwendung von plasminogen zur wundheilung ATE552842T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31764301P 2001-09-06 2001-09-06

Publications (1)

Publication Number Publication Date
ATE552842T1 true ATE552842T1 (de) 2012-04-15

Family

ID=23234611

Family Applications (2)

Application Number Title Priority Date Filing Date
AT02797695T ATE348631T1 (de) 2001-09-06 2002-09-06 Verwendung von plasminogen zur heilung von zerbrochenen trommelfellen
AT06126236T ATE552842T1 (de) 2001-09-06 2002-09-06 Verwendung von plasminogen zur wundheilung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT02797695T ATE348631T1 (de) 2001-09-06 2002-09-06 Verwendung von plasminogen zur heilung von zerbrochenen trommelfellen

Country Status (9)

Country Link
US (3) US7067492B2 (de)
EP (2) EP1427440B1 (de)
CN (2) CN1961958B (de)
AT (2) ATE348631T1 (de)
AU (1) AU2002361878A1 (de)
DE (1) DE60216939T2 (de)
DK (2) DK1427440T3 (de)
ES (2) ES2279001T3 (de)
WO (1) WO2003020297A2 (de)

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US7067492B2 (en) * 2001-09-06 2006-06-27 Omnio Ab Method of promoting healing of a tympanic membrane perforation
US20070038298A1 (en) * 2005-06-30 2007-02-15 Sulner Joseph W Repair of tympanic membrane using placenta derived collagen biofabric
CA2649688A1 (en) * 2006-03-14 2007-09-20 Oregon Health & Science University Methods for detecting a mycobacterium tuberculosis infection
WO2008021391A1 (en) 2006-08-15 2008-02-21 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
CA2662083C (en) * 2006-08-28 2016-09-20 Omnio Healer Ab Novel drug target of preventing and treating periodontal disease, improving healing of periodontal wounds and promoting oral health
CN101563100B (zh) * 2006-08-28 2013-08-07 李季男 用于预防和治疗牙周病、改善牙周创伤愈合以及促进口腔健康的新药物靶标
US8071135B2 (en) 2006-10-04 2011-12-06 Anthrogenesis Corporation Placental tissue compositions
NZ597223A (en) 2006-10-06 2013-09-27 Anthrogenesis Corp Native (telopeptide) placental collagen compositions
US9174042B2 (en) * 2007-05-25 2015-11-03 Empi, Inc. Wound healing electrode set
GB2450747A (en) * 2007-07-06 2009-01-07 Univ Sheffield Treatment of sensorineural hearing loss
US20110142819A1 (en) * 2008-01-22 2011-06-16 Omnio Healer Ab Method of improving would healing
RU2432396C2 (ru) * 2009-11-24 2011-10-27 Федеральное государственное учреждение "Российский кардиологический научно-производственный комплекс" Министерства здравоохранения и социального развития Российской Федерации (ФГУ "РКНПК" Минздравсоцразвития России) РЕКОМБИНАНТНЫЙ ПОЛИПЕПТИД СО СВОЙСТВАМИ ПЛАЗМИНОГЕНА ЧЕЛОВЕКА ПРЕВРАЩАТЬСЯ ПРИ АКТИВАЦИИ В ПЛАЗМИН, КОТОРЫЙ КАТАЛИЗИРУЕТ РАСЩЕПЛЕНИЕ ФИБРИНА, ФРАГМЕНТ ДНК, КОДИРУЮЩИЙ ПОЛИПЕПТИД, РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК ДЛЯ ЭКСПРЕССИИ ПОЛИПЕПТИДА И ТРАНСФОРМИРОВАННАЯ КЛЕТКА Escherichia coli - ПРОДУЦЕНТ ПОЛИПЕПТИДА
RU2432397C2 (ru) * 2009-11-24 2011-10-27 Федеральное государственное учреждение "Российский кардиологический научно-производственный комплекс" Министерства здравоохранения и социального развития Российской Федерации (ФГУ "РКНПК" Минздравсоцразвития России) РЕКОМБИНАНТНЫЙ ПОЛИПЕПТИД СО СВОЙСТВАМИ ПЛАЗМИНОГЕНА ЧЕЛОВЕКА ПРЕВРАЩАТЬСЯ ПРИ АКТИВАЦИИ В ПЛАЗМИН, КОТОРЫЙ КАТАЛИЗИРУЕТ РАСЩЕПЛЕНИЕ ФИБРИНА, ФРАГМЕНТ ДНК, КОДИРУЮЩИЙ ПОЛИПЕПТИД, РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК ДЛЯ ЭКСПРЕССИИ ПОЛИПЕПТИДА И ТРАНСФОРМИРОВАННАЯ КЛЕТКА Escherichia coli - ПРОДУЦЕНТ ПОЛИПЕПТИДА
HUE049294T2 (hu) 2013-05-15 2020-09-28 Univ Leland Stanford Junior Heparinkötõ epidermális növekedési faktor aktivitás modulálása dobhártya gyógyításához
TWI801331B (zh) * 2015-11-03 2023-05-11 美商波麥堤克生物治療股份有限公司 纖維蛋白溶酶原缺乏症之纖維蛋白溶酶原替代療法
TW201722464A (zh) * 2015-11-10 2017-07-01 波麥堤克生化科學有限公司 用於傷口癒合之纖維蛋白溶酶原給藥方案
WO2017101873A1 (zh) * 2015-12-18 2017-06-22 深圳瑞健生命科学研究院有限公司 一种预防或治疗放射性和化学性损伤的方法
WO2017101872A1 (zh) 2015-12-18 2017-06-22 深圳瑞健生命科学研究院有限公司 一种用于预防和治疗宫颈糜烂的方法
US11338022B2 (en) 2015-12-18 2022-05-24 Talengen International Limited Method for preventing and treating angiocardiopathy
US10709771B2 (en) 2015-12-18 2020-07-14 Talengen International Limited Method for preventing or treating diabetic retinopathy
CA3008686C (en) 2015-12-18 2023-03-14 Talengen International Limited Method for preventing and treating diabetic nephropathy
CN109069567A (zh) * 2015-12-18 2018-12-21 泰伦基国际有限公司 一种预防或治疗糖尿病性神经损伤及其相关病症的方法
US10590184B2 (en) * 2016-09-26 2020-03-17 National Yang-Ming University Process for a preparation of the modified porcine plasma fibronectin for enhance wound healing
EP3556385A4 (de) * 2016-12-15 2020-12-30 Talengen International Limited Verfahren zur verringerung von herzerkrankungen
WO2018107703A1 (zh) 2016-12-15 2018-06-21 深圳瑞健生命科学研究院有限公司 一种促进胰岛β细胞损伤修复和减少胰岛纤维化的方法
CN110191718A (zh) 2016-12-15 2019-08-30 泰伦基国际有限公司 一种预防和治疗组织器官纤维化的方法
WO2018107690A1 (zh) 2016-12-15 2018-06-21 深圳瑞健生命科学研究院有限公司 一种预防和治疗肥胖症的方法
CN108210905A (zh) * 2016-12-15 2018-06-29 深圳瑞健生命科学研究院有限公司 预防和治疗皮肤纤维化的药物及其用途
CN108339114A (zh) * 2016-12-15 2018-07-31 深圳瑞健生命科学研究院有限公司 抑制胰岛β细胞凋亡的药物及其用途
JP7168990B2 (ja) 2016-12-15 2022-11-10 タレンゲン インターナショナル リミテッド 肥満症を予防および治療するための方法および薬物
JP7335609B2 (ja) 2017-06-19 2023-08-30 タレンゲン インターナショナル リミテッド Ｇｌｐ－１／ｇｌｐ－１ｒを調節制御する方法および薬剤
JP2023550301A (ja) * 2020-11-25 2023-12-01 グリフォルス・ワールドワイド・オペレーションズ・リミテッド 創傷治癒

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990013640A1 (en) * 1989-05-01 1990-11-15 The University Of Notre Dame Du Lac Methods and materials for expression of human plasminogen in a eukaryotic cell system
US6197325B1 (en) * 1990-11-27 2001-03-06 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6559119B1 (en) * 1990-11-27 2003-05-06 Loyola University Of Chicago Method of preparing a tissue sealant-treated biomedical material
ATE226089T1 (de) * 1995-01-27 2002-11-15 Tno Verwendung einer zubereitung enthaltend einen plasminogen-aktivator für die verbesserung der wundheilung
JPH11507697A (ja) * 1995-06-09 1999-07-06 エヌ． ドロハン，ウィリアム キチンヒドロゲル、それらの製造方法及び利用
US6043407A (en) * 1997-07-29 2000-03-28 Warner-Lambert Company Debridement pad
CA2352477A1 (en) * 1998-11-25 2000-06-02 Richard-Weidong Ji Compositions comprising angiostatin and kringle 5 region of plasminogen and methods of use thereof
WO2000061179A1 (en) * 1999-04-14 2000-10-19 Karolinska Innovations Ab Kringle domains of plasminogen, capable of modulating angiogenesis in vivo
US7067492B2 (en) * 2001-09-06 2006-06-27 Omnio Ab Method of promoting healing of a tympanic membrane perforation
US7202066B2 (en) * 2002-01-29 2007-04-10 Carrington Laboratories, Inc. Combination of a growth factor and a protease enzyme

Also Published As

Publication number Publication date
WO2003020297A2 (en) 2003-03-13
WO2003020297A8 (en) 2004-07-08
US20070041962A1 (en) 2007-02-22
ES2387797T3 (es) 2012-10-01
WO2003020297A3 (en) 2003-10-09
DK1427440T3 (da) 2007-04-30
CN1961958A (zh) 2007-05-16
US20080090751A1 (en) 2008-04-17
ES2279001T3 (es) 2007-08-16
US8679482B2 (en) 2014-03-25
EP1790354A2 (de) 2007-05-30
US7067492B2 (en) 2006-06-27
EP1427440A2 (de) 2004-06-16
US20030147879A1 (en) 2003-08-07
CN1585649A (zh) 2005-02-23
DE60216939D1 (de) 2007-02-01
EP1790354B1 (de) 2012-04-11
CN1961958B (zh) 2011-05-18
DK1790354T3 (da) 2012-07-23
CN1289145C (zh) 2006-12-13
EP1427440B1 (de) 2006-12-20
EP1790354A3 (de) 2007-10-24
DE60216939T2 (de) 2007-10-04
AU2002361878A1 (en) 2003-03-18
ATE348631T1 (de) 2007-01-15
US8637010B2 (en) 2014-01-28

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