ATE348648T1 - Synergistische zusammensetzung aus trans-tetracos-15-ensäure und apocynin, und verwendung davon - Google Patents
Synergistische zusammensetzung aus trans-tetracos-15-ensäure und apocynin, und verwendung davonInfo
- Publication number
- ATE348648T1 ATE348648T1 AT02722566T AT02722566T ATE348648T1 AT E348648 T1 ATE348648 T1 AT E348648T1 AT 02722566 T AT02722566 T AT 02722566T AT 02722566 T AT02722566 T AT 02722566T AT E348648 T1 ATE348648 T1 AT E348648T1
- Authority
- AT
- Austria
- Prior art keywords
- tetracos
- trans
- acid
- apocynine
- enene
- Prior art date
Links
- DFYRUELUNQRZTB-UHFFFAOYSA-N apocynin Chemical compound COC1=CC(C(C)=O)=CC=C1O DFYRUELUNQRZTB-UHFFFAOYSA-N 0.000 title abstract 5
- 230000002195 synergetic effect Effects 0.000 title abstract 2
- -1 TRANS-TETRACOS-15-ENENE Chemical group 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 229930188866 apocynin Natural products 0.000 abstract 2
- 206010019851 Hepatotoxicity Diseases 0.000 abstract 1
- GWHCXVQVJPWHRF-UHFFFAOYSA-N cis-tetracosenoic acid Natural products CCCCCCCCC=CCCCCCCCCCCCCCC(O)=O GWHCXVQVJPWHRF-UHFFFAOYSA-N 0.000 abstract 1
- 230000002443 hepatoprotective effect Effects 0.000 abstract 1
- 230000007686 hepatotoxicity Effects 0.000 abstract 1
- 231100000304 hepatotoxicity Toxicity 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- GWHCXVQVJPWHRF-MDZDMXLPSA-N trans-selacholeic acid Chemical compound CCCCCCCC\C=C\CCCCCCCCCCCCCC(O)=O GWHCXVQVJPWHRF-MDZDMXLPSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02722566A EP1509285B1 (de) | 2002-03-25 | 2002-03-25 | Synergistische zusammensetzung aus trans-tetracos-15-ensäure und apocynin, und verwendung davon |
| PCT/IB2002/001212 WO2003080081A2 (en) | 2002-03-25 | 2002-03-25 | Synergistic composition of trans-tetracos-15-enoic acid and apocynin and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE348648T1 true ATE348648T1 (de) | 2007-01-15 |
Family
ID=28053185
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02722566T ATE348648T1 (de) | 2002-03-25 | 2002-03-25 | Synergistische zusammensetzung aus trans-tetracos-15-ensäure und apocynin, und verwendung davon |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1509285B1 (de) |
| JP (1) | JP4299147B2 (de) |
| CN (1) | CN1269475C (de) |
| AT (1) | ATE348648T1 (de) |
| AU (1) | AU2002253445A1 (de) |
| DE (1) | DE60216979T2 (de) |
| WO (1) | WO2003080081A2 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1602926A1 (de) * | 2004-06-04 | 2005-12-07 | University of Geneva | Neue Mittel und Verfahren zur Behandlung von Gehörverlust oder Tinnitus |
| CN108610285B (zh) * | 2017-03-17 | 2020-04-28 | 上海柏翱纳吉医药科技有限公司 | 苯乙酮类化合物、其制备方法及其在防治脂肪肝方面的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999012539A1 (en) * | 1997-09-10 | 1999-03-18 | The Johns Hopkins University School Of Medicine | The use of an nadph-oxidase inhibitor in the treatment of reperfusion injury |
| US6492429B1 (en) * | 2000-07-10 | 2002-12-10 | N.V. Nutricia | Composition for the treatment of osteoarthritis |
| GB2368012A (en) * | 2000-10-19 | 2002-04-24 | Nicholas John Larkins | Preparation for the relief of inflammatory disease |
-
2002
- 2002-03-25 EP EP02722566A patent/EP1509285B1/de not_active Expired - Lifetime
- 2002-03-25 WO PCT/IB2002/001212 patent/WO2003080081A2/en not_active Ceased
- 2002-03-25 AU AU2002253445A patent/AU2002253445A1/en not_active Abandoned
- 2002-03-25 AT AT02722566T patent/ATE348648T1/de active
- 2002-03-25 DE DE60216979T patent/DE60216979T2/de not_active Expired - Lifetime
- 2002-03-25 CN CNB02828951XA patent/CN1269475C/zh not_active Expired - Fee Related
- 2002-03-25 JP JP2003577907A patent/JP4299147B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003080081A3 (en) | 2004-12-23 |
| DE60216979T2 (de) | 2007-08-30 |
| DE60216979D1 (de) | 2007-02-01 |
| WO2003080081A2 (en) | 2003-10-02 |
| CN1269475C (zh) | 2006-08-16 |
| JP2005526098A (ja) | 2005-09-02 |
| EP1509285A2 (de) | 2005-03-02 |
| AU2002253445A8 (en) | 2003-10-08 |
| JP4299147B2 (ja) | 2009-07-22 |
| AU2002253445A1 (en) | 2003-10-08 |
| CN1625422A (zh) | 2005-06-08 |
| EP1509285B1 (de) | 2006-12-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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