ATE349548T1 - Verfahren zur erkennung, analyse und isolierung von freiwerdenden proteinen - Google Patents

Verfahren zur erkennung, analyse und isolierung von freiwerdenden proteinen

Info

Publication number
ATE349548T1
ATE349548T1 AT00957758T AT00957758T ATE349548T1 AT E349548 T1 ATE349548 T1 AT E349548T1 AT 00957758 T AT00957758 T AT 00957758T AT 00957758 T AT00957758 T AT 00957758T AT E349548 T1 ATE349548 T1 AT E349548T1
Authority
AT
Austria
Prior art keywords
analysis
detection
markers
isolation
released proteins
Prior art date
Application number
AT00957758T
Other languages
English (en)
Inventor
Kenneth J Rothschild
Sadanand Gite
Jerzy Olejnik
Original Assignee
Ambergen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/382,950 external-priority patent/US6303337B1/en
Priority claimed from US09/382,736 external-priority patent/US6306628B1/en
Application filed by Ambergen Inc filed Critical Ambergen Inc
Application granted granted Critical
Publication of ATE349548T1 publication Critical patent/ATE349548T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1062Isolating an individual clone by screening libraries mRNA-Display, e.g. polypeptide and encoding template are connected covalently
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT00957758T 1999-08-25 2000-08-23 Verfahren zur erkennung, analyse und isolierung von freiwerdenden proteinen ATE349548T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/382,950 US6303337B1 (en) 1999-08-25 1999-08-25 N-terminal and C-terminal markers in nascent proteins
US09/382,736 US6306628B1 (en) 1999-08-25 1999-08-25 Methods for the detection, analysis and isolation of Nascent proteins

Publications (1)

Publication Number Publication Date
ATE349548T1 true ATE349548T1 (de) 2007-01-15

Family

ID=27009892

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00957758T ATE349548T1 (de) 1999-08-25 2000-08-23 Verfahren zur erkennung, analyse und isolierung von freiwerdenden proteinen

Country Status (7)

Country Link
EP (2) EP1210449B1 (de)
JP (1) JP5565989B2 (de)
AT (1) ATE349548T1 (de)
AU (1) AU775940B2 (de)
CA (1) CA2383554C (de)
DE (2) DE60045879D1 (de)
WO (1) WO2001014578A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7312060B2 (en) * 1999-08-25 2007-12-25 Ambergen, Inc. Methods for the detection, analysis and isolation of nascent proteins
US6306628B1 (en) * 1999-08-25 2001-10-23 Ambergen, Incorporated Methods for the detection, analysis and isolation of Nascent proteins
EP1669448A4 (de) * 2003-09-25 2007-10-31 Cellfree Sciences Co Ltd Verfahren zur herstellung einer antigenen substanz
EP2343304B1 (de) 2005-02-16 2015-06-10 Anacor Pharmaceuticals, Inc. Biozide Boronophthalidverbindungen
KR20080110984A (ko) 2005-12-30 2008-12-22 아나코르 파마슈티칼스 인코포레이티드 보론함유 소분자
PT1988779E (pt) 2006-02-16 2015-09-04 Anacor Pharmaceuticals Inc Moléculas pequenas contendo boro como agentes antiinflamatórios
KR20150065941A (ko) 2008-03-06 2015-06-15 아나코르 파마슈티칼스 인코포레이티드 소염제로써 붕소가 함유된 소분자
EP2348863A4 (de) 2008-09-04 2012-03-07 Anacor Pharmaceuticals Inc Borhaltige kleine moleküle
WO2010028005A1 (en) 2008-09-04 2010-03-11 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
AP4039A (en) 2009-08-14 2017-02-28 Daitao Chen Boron-containing small molecules as antiprotozoal agents
WO2011049971A1 (en) 2009-10-20 2011-04-28 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as antiprotozoal agents
WO2011060196A1 (en) 2009-11-11 2011-05-19 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
WO2011094450A1 (en) 2010-01-27 2011-08-04 Anacor Pharmaceuticals, Inc Boron-containing small molecules
AP2012006482A0 (en) 2010-03-19 2012-10-31 Anacor Pharmacueticals Inc Boron-containing small molecules as anti-protozoalagent
SI3251678T1 (sl) 2010-09-07 2022-01-31 Anacor Pharmaceuticals, Inc. Derivati benzoksaborola za zdravljenje bakterijskih okužb
US20240092820A1 (en) * 2020-11-25 2024-03-21 Sony Group Corporation Polymer dyes

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675285A (en) 1984-09-19 1987-06-23 Genetics Institute, Inc. Method for identification and isolation of DNA encoding a desired protein
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4774339A (en) 1987-08-10 1988-09-27 Molecular Probes, Inc. Chemically reactive dipyrrometheneboron difluoride dyes
JPH083481B2 (ja) 1989-06-07 1996-01-17 日立ソフトウェアエンジニアリング株式会社 蛍光式電気泳動パターン読み取り装置
US5091328A (en) 1989-11-21 1992-02-25 National Semiconductor Corporation Method of late programming MOS devices
US5274113A (en) * 1991-11-01 1993-12-28 Molecular Probes, Inc. Long wavelength chemically reactive dipyrrometheneboron difluoride dyes and conjugates
US5248782A (en) 1990-12-18 1993-09-28 Molecular Probes, Inc. Long wavelength heteroaryl-substituted dipyrrometheneboron difluoride dyes
JP2873884B2 (ja) 1991-03-22 1999-03-24 日立ソフトウェアエンジニアリング 株式会社 多色泳動パターン読み取り装置
US5187288A (en) 1991-05-22 1993-02-16 Molecular Probes, Inc. Ethenyl-substituted dipyrrometheneboron difluoride dyes and their synthesis
US5137609A (en) 1992-01-31 1992-08-11 Biometric Imaging Inc. Differential separation assay
US5656451A (en) 1993-07-30 1997-08-12 Yale University OspE, OspF, and S1 polypeptides in borrelia burgdorferi
US5643722A (en) * 1994-05-11 1997-07-01 Trustees Of Boston University Methods for the detection and isolation of proteins
JPH07313169A (ja) 1994-05-26 1995-12-05 Nippon Ham Kk 骨形成因子受容体改変体の遺伝子
US5876940A (en) * 1994-11-30 1999-03-02 University Of Utah Research Foundation Alleles
US5654150A (en) 1995-06-07 1997-08-05 President And Fellows Of Harvard College Method of expression cloning
US5851804A (en) * 1996-05-06 1998-12-22 Apollon, Inc. Chimeric kanamycin resistance gene
EP0931160B1 (de) * 1996-09-13 2008-12-17 Alex M. Garvin Nachweis von mutationen mittels in vitro synthetisierten proteinen mit peptid-markierung
AU3909199A (en) * 1997-12-15 1999-07-05 Nexstar Pharmaceuticals, Inc. Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction
DE10107317A1 (de) * 2001-02-16 2002-09-12 Max Planck Gesellschaft Methode zur Detektion von Mutationen
DE10158904A1 (de) * 2001-11-30 2003-06-12 Roche Diagnostics Gmbh Verfahren zur Herstellung von linearen DNA Fragmenten für die in vitro Expression von Proteinen

Also Published As

Publication number Publication date
EP1767629B1 (de) 2011-04-20
CA2383554A1 (en) 2001-03-01
EP1210449B1 (de) 2006-12-27
EP1767629A2 (de) 2007-03-28
DE60045879D1 (de) 2011-06-01
EP1767629A3 (de) 2009-04-01
JP2004513604A (ja) 2004-05-13
WO2001014578A1 (en) 2001-03-01
EP1210449A1 (de) 2002-06-05
AU6932800A (en) 2001-03-19
DE60032614D1 (de) 2007-02-08
AU775940B2 (en) 2004-08-19
EP1210449A4 (de) 2005-01-05
JP5565989B2 (ja) 2014-08-06
CA2383554C (en) 2008-03-18

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