|
US6150328A
(en)
|
1986-07-01 |
2000-11-21 |
Genetics Institute, Inc. |
BMP products
|
|
US20070166353A1
(en)
*
|
1988-04-08 |
2007-07-19 |
Stryker Corporation |
Osteogenic proteins
|
|
US6586388B2
(en)
*
|
1988-04-08 |
2003-07-01 |
Stryker Corporation |
Method of using recombinant osteogenic protein to repair bone or cartilage defects
|
|
US6919308B2
(en)
*
|
1988-04-08 |
2005-07-19 |
Stryker Corporation |
Osteogenic devices
|
|
DE68929453T2
(de)
*
|
1988-04-08 |
2003-11-20 |
Stryker Corp., Kalamazoo |
Osteogene Vorrichtungen
|
|
US5266683A
(en)
*
|
1988-04-08 |
1993-11-30 |
Stryker Corporation |
Osteogenic proteins
|
|
US5645591A
(en)
|
1990-05-29 |
1997-07-08 |
Stryker Corporation |
Synthetic bone matrix
|
|
US5674844A
(en)
*
|
1991-03-11 |
1997-10-07 |
Creative Biomolecules, Inc. |
Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases
|
|
US7056882B2
(en)
*
|
1991-03-11 |
2006-06-06 |
Curis, Inc. |
Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases
|
|
KR100259827B1
(ko)
|
1991-11-04 |
2000-06-15 |
브루스 엠. 에이센, 토마스 제이 데스로저 |
재조합 골형태 형성 단백질 헤테로다이머, 그 조성물 및 사용방법
|
|
US20080233170A1
(en)
*
|
1992-02-21 |
2008-09-25 |
Stryker Corporation |
Osteogenic Proteins
|
|
US5362442A
(en)
*
|
1993-07-22 |
1994-11-08 |
2920913 Canada Inc. |
Method for sterilizing products with gamma radiation
|
|
US20040067157A1
(en)
*
|
1993-07-22 |
2004-04-08 |
Clearant, Inc. |
Methods for sterilizing biological materials
|
|
US6291206B1
(en)
|
1993-09-17 |
2001-09-18 |
Genetics Institute, Inc. |
BMP receptor proteins
|
|
EP0733109B9
(de)
|
1993-12-07 |
2006-07-05 |
Genetics Institute, LLC |
Bmp-12, bmp-13 und diese enthaltende sehne-induzierende zusammensetzungen
|
|
US5674292A
(en)
|
1995-06-07 |
1997-10-07 |
Stryker Corporation |
Terminally sterilized osteogenic devices and preparation thereof
|
|
ES2218668T3
(es)
*
|
1996-10-23 |
2004-11-16 |
Sdgi Holdings, Inc. |
Espaciador espinal.
|
|
ES2113834B1
(es)
*
|
1996-11-12 |
1999-01-01 |
Univ Vigo |
Metodo de mejora de la osteointegracion de implantes de fijacion osea.
|
|
AU716137B2
(en)
*
|
1997-01-16 |
2000-02-17 |
Cohesion Corporation |
Lyophilized collagen-based biomaterials, process of preparation and uses thereof
|
|
AU6267798A
(en)
*
|
1997-02-07 |
1998-08-26 |
Stryker Corporation |
Matrix-free osteogenic devices, implants and methods of use thereof
|
|
US7041641B2
(en)
|
1997-03-20 |
2006-05-09 |
Stryker Corporation |
Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects
|
|
US20010016646A1
(en)
*
|
1998-03-20 |
2001-08-23 |
David C. Rueger |
Osteogenic devices and methods of use thereof for repair of endochondral bone, osteochondral and chondral defects
|
|
US20030032586A1
(en)
*
|
1997-05-15 |
2003-02-13 |
David C. Rueger |
Compositions for morphogen-induced osteogenesis
|
|
JP2001526788A
(ja)
|
1997-05-30 |
2001-12-18 |
クリエイティブ バイオモレキュールズ,インコーポレイテッド |
組織形態形成および活性を評価するための方法
|
|
US20010031254A1
(en)
*
|
1998-11-13 |
2001-10-18 |
Bianchi John R. |
Assembled implant
|
|
US6482584B1
(en)
|
1998-11-13 |
2002-11-19 |
Regeneration Technologies, Inc. |
Cyclic implant perfusion cleaning and passivation process
|
|
DE19803673A1
(de)
*
|
1998-01-30 |
1999-08-05 |
Norbert M Dr Meenen |
Biohybrider Gelenkflächenersatz
|
|
US20040081704A1
(en)
|
1998-02-13 |
2004-04-29 |
Centerpulse Biologics Inc. |
Implantable putty material
|
|
US7147839B2
(en)
|
1998-05-29 |
2006-12-12 |
Curis, Inc. |
Methods for evaluating tissue morphogenesis and activity
|
|
GB9820457D0
(en)
|
1998-09-18 |
1998-11-11 |
Medlogic Global Corp |
Methods for sterilizing cyanoacrylate compositions
|
|
EP1649865B1
(de)
*
|
1998-10-06 |
2012-06-13 |
Stryker Corporation |
GDF-5 zur Verwendung für das Reparieren eines nicht-artikulären Knorpelgewebedefekts in einer Bandscheibe
|
|
US6958149B2
(en)
*
|
1998-10-06 |
2005-10-25 |
Stryker Corporation |
Repair of larynx, trachea, and other fibrocartilaginous tissues
|
|
MXPA01003538A
(es)
*
|
1998-10-06 |
2005-09-08 |
Rush Presbyterian St Luke |
Metodo para el tratamiento de quimionucleolisis.
|
|
US7572440B2
(en)
|
1999-07-30 |
2009-08-11 |
Stryker Corporation |
Method for repairing a defect in an intervertebral disc
|
|
US6846906B1
(en)
|
1998-10-07 |
2005-01-25 |
Stryker Corporation |
Modified proteins of the TGF-β superfamily, including morphogenic proteins
|
|
US6677432B1
(en)
|
1998-10-07 |
2004-01-13 |
Stryker Corporation |
Mutations of the C-terminal portion of TGF-β superfamily proteins
|
|
JP3762222B2
(ja)
|
1998-10-07 |
2006-04-05 |
ストライカー・コーポレーション |
改変型TGF−βスーパーファミリータンパク質
|
|
GB2344519B
(en)
*
|
1998-12-07 |
2004-05-19 |
Johnson & Johnson Medical Ltd |
Sterile therapeutic compositions
|
|
JP2000169498A
(ja)
*
|
1998-12-10 |
2000-06-20 |
Natl Food Res Inst |
タンパク質の溶解性改善方法
|
|
US6727224B1
(en)
|
1999-02-01 |
2004-04-27 |
Genetics Institute, Llc. |
Methods and compositions for healing and repair of articular cartilage
|
|
DE60020526T2
(de)
|
1999-02-04 |
2006-05-11 |
SDGI Holdings, Inc., Wilmington |
Osteogene pastenzusammensetzungen und ihre verwendung
|
|
EP1027897B1
(de)
*
|
1999-02-10 |
2005-04-13 |
IsoTis N.V. |
Verfahren zur Knorpelgeweberegeneration
|
|
WO2000047114A1
(en)
*
|
1999-02-12 |
2000-08-17 |
Collagenesis, Inc. |
Injectable collagen-based delivery system for bone morphogenic proteins
|
|
EP1223990B1
(de)
|
1999-10-15 |
2004-07-28 |
Genetics Institute, LLC |
Hyaluronsäure enthaltende zusammensetzungen zur abgabe osteogener proteine
|
|
US6698162B2
(en)
*
|
2000-03-23 |
2004-03-02 |
Teikoku Pharma Usa, Inc. |
Methods of producing a terminally sterilized topical patch preparation
|
|
US20040086420A1
(en)
*
|
2000-03-23 |
2004-05-06 |
Macphee Martin J. |
Methods for sterilizing serum or plasma
|
|
EP1762251A1
(de)
*
|
2000-03-23 |
2007-03-14 |
Clearant, Inc. |
Verfahren zum Sterilisieren biologischen Materials
|
|
US6521244B1
(en)
*
|
2000-06-13 |
2003-02-18 |
Nozomu Kanesaka |
Body filling material
|
|
US6800245B1
(en)
|
2000-11-28 |
2004-10-05 |
Vita Special Purpose Corporation |
Sterile polymerizable systems and kits and methods of their manufacture and use
|
|
US20020114795A1
(en)
|
2000-12-22 |
2002-08-22 |
Thorne Kevin J. |
Composition and process for bone growth and repair
|
|
WO2002070024A1
(en)
*
|
2001-01-04 |
2002-09-12 |
Osteotech, Inc. |
Method for sterilizing bioactive materials
|
|
US6682695B2
(en)
*
|
2001-03-23 |
2004-01-27 |
Clearant, Inc. |
Methods for sterilizing biological materials by multiple rates
|
|
US7226587B2
(en)
|
2001-06-01 |
2007-06-05 |
Wyeth |
Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
|
|
RU2182018C1
(ru)
*
|
2001-06-06 |
2002-05-10 |
Научно-исследовательский и учебно-методический центр биомедицинских технологий ВИЛАР |
Способ определения in vitro остеоинтегративных свойств материалов для костных имплантатов
|
|
TWI267378B
(en)
|
2001-06-08 |
2006-12-01 |
Wyeth Corp |
Calcium phosphate delivery vehicles for osteoinductive proteins
|
|
US6696060B2
(en)
|
2001-06-14 |
2004-02-24 |
Clearant, Inc. |
Methods for sterilizing preparations of monoclonal immunoglobulins
|
|
US6946098B2
(en)
|
2001-08-10 |
2005-09-20 |
Clearant, Inc. |
Methods for sterilizing biological materials
|
|
US20030031584A1
(en)
*
|
2001-08-10 |
2003-02-13 |
Wilson Burgess |
Methods for sterilizing biological materials using dipeptide stabilizers
|
|
US7252799B2
(en)
*
|
2001-08-31 |
2007-08-07 |
Clearant, Inc. |
Methods for sterilizing preparations containing albumin
|
|
US6749851B2
(en)
*
|
2001-08-31 |
2004-06-15 |
Clearant, Inc. |
Methods for sterilizing preparations of digestive enzymes
|
|
US20030095890A1
(en)
*
|
2001-09-24 |
2003-05-22 |
Shirley Miekka |
Methods for sterilizing biological materials containing non-aqueous solvents
|
|
US20110091353A1
(en)
*
|
2001-09-24 |
2011-04-21 |
Wilson Burgess |
Methods for Sterilizing Tissue
|
|
US6783968B2
(en)
*
|
2001-09-24 |
2004-08-31 |
Clearant, Inc. |
Methods for sterilizing preparations of glycosidases
|
|
US20030185702A1
(en)
*
|
2002-02-01 |
2003-10-02 |
Wilson Burgess |
Methods for sterilizing tissue
|
|
AU2002359407B2
(en)
|
2001-11-14 |
2008-02-28 |
Durect Corporation |
Catheter injectable depot compositions and uses thereof
|
|
NZ533434A
(en)
*
|
2001-11-14 |
2006-11-30 |
Alza Corp |
Thixotropic gel composition for injectable deposition
|
|
US20030124023A1
(en)
*
|
2001-12-21 |
2003-07-03 |
Wilson Burgess |
Method of sterilizing heart valves
|
|
US7357895B2
(en)
|
2002-01-04 |
2008-04-15 |
Osteotech, Inc. |
Method for sterilizing bioactive materials
|
|
US20030180181A1
(en)
*
|
2002-02-01 |
2003-09-25 |
Teri Greib |
Methods for sterilizing tissue
|
|
WO2003066000A2
(en)
*
|
2002-02-08 |
2003-08-14 |
Wyeth |
Formulation comprising bioactive agents and method of using same
|
|
US7166133B2
(en)
|
2002-06-13 |
2007-01-23 |
Kensey Nash Corporation |
Devices and methods for treating defects in the tissue of a living being
|
|
US20040001889A1
(en)
|
2002-06-25 |
2004-01-01 |
Guohua Chen |
Short duration depot formulations
|
|
US7744597B2
(en)
|
2002-06-26 |
2010-06-29 |
Lifenet Health |
Device and process for producing fiber products and fiber products produced thereby
|
|
US7498040B2
(en)
*
|
2005-10-12 |
2009-03-03 |
Lifenet Health |
Compositions for repair of defects in osseous tissues, and methods of making the same
|
|
US6908591B2
(en)
*
|
2002-07-18 |
2005-06-21 |
Clearant, Inc. |
Methods for sterilizing biological materials by irradiation over a temperature gradient
|
|
US20040013561A1
(en)
*
|
2002-07-18 |
2004-01-22 |
David Mann |
Methods for sterilizing recombinant or transgenic material
|
|
WO2004012703A1
(en)
|
2002-07-31 |
2004-02-12 |
Alza Corporation |
Injectable depot compositions and uses thereof
|
|
CN1684663A
(zh)
|
2002-07-31 |
2005-10-19 |
阿尔萨公司 |
可注射的多模式聚合物储库组合物以及其用途
|
|
EP1589902A1
(de)
*
|
2003-01-27 |
2005-11-02 |
Medtronic Vascular Connaught |
Verbesserte verpackung für stentanbringungssystem
|
|
US7067123B2
(en)
|
2003-04-29 |
2006-06-27 |
Musculoskeletal Transplant Foundation |
Glue for cartilage repair
|
|
US7494811B2
(en)
|
2003-05-01 |
2009-02-24 |
Lifenet Health |
In vitro growth of tissues suitable to the formation of bone and bone forming tissue formed thereby
|
|
US7901457B2
(en)
|
2003-05-16 |
2011-03-08 |
Musculoskeletal Transplant Foundation |
Cartilage allograft plug
|
|
US20050003007A1
(en)
*
|
2003-07-02 |
2005-01-06 |
Michele Boix |
Method of sterilization of polymeric microparticles
|
|
TW200518767A
(en)
*
|
2003-09-12 |
2005-06-16 |
Wyeth Corp |
Injectable calcium phosphate solid rods and pastes for delivery of osteogenic proteins
|
|
US7695674B2
(en)
*
|
2003-09-29 |
2010-04-13 |
Medtronic Vascular, Inc. |
Method of sterilizing balloon with ionizing radiation
|
|
EP2335650B1
(de)
|
2003-12-11 |
2012-10-03 |
Isto Technologies Inc. |
Teilchenförmiges Knorpelsystem
|
|
US7678385B2
(en)
*
|
2004-04-28 |
2010-03-16 |
Biomet Manufacturing Corp. |
Irradiated implantable bone material
|
|
US20050244450A1
(en)
*
|
2004-04-28 |
2005-11-03 |
Reddi A H |
Heat-treated implantable bone material
|
|
US20060194726A1
(en)
*
|
2004-05-25 |
2006-08-31 |
Rueger David C |
Methods of treating cartilage defects
|
|
CA2567405A1
(en)
*
|
2004-05-25 |
2005-12-08 |
Stryker Corporation |
Use of morphogenic proteins for treating cartilage defects
|
|
WO2005120454A2
(en)
*
|
2004-06-09 |
2005-12-22 |
Scil Technology Gmbh |
Composite material for use as protein carrier
|
|
US20050288796A1
(en)
*
|
2004-06-23 |
2005-12-29 |
Hani Awad |
Native soft tissue matrix for therapeutic applications
|
|
DE102004036881A1
(de)
*
|
2004-07-22 |
2006-02-16 |
Ossacur Ag |
Bioresorbierbares Material zur Füllung von Knochendefekten
|
|
DE102004036882A1
(de)
*
|
2004-07-22 |
2006-02-16 |
Ossacur Ag |
Bioresorbierbares Material zur Füllung von Knochendefekten
|
|
US8697139B2
(en)
|
2004-09-21 |
2014-04-15 |
Frank M. Phillips |
Method of intervertebral disc treatment using articular chondrocyte cells
|
|
US7837740B2
(en)
*
|
2007-01-24 |
2010-11-23 |
Musculoskeletal Transplant Foundation |
Two piece cancellous construct for cartilage repair
|
|
US20080220044A1
(en)
*
|
2007-03-06 |
2008-09-11 |
Semler Eric J |
Cancellous construct with support ring for repair of osteochondral defects
|
|
US20090319045A1
(en)
*
|
2004-10-12 |
2009-12-24 |
Truncale Katherine G |
Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
|
|
US7993578B2
(en)
|
2004-10-29 |
2011-08-09 |
Depuy Spine, Inc. |
Methods and kits for aseptic filling of products
|
|
US20060166251A1
(en)
*
|
2005-01-26 |
2006-07-27 |
Archambault Joanne M |
Use of sFRPs as markers of BMP activity
|
|
JP2008534607A
(ja)
*
|
2005-03-30 |
2008-08-28 |
ワイス |
Bmpを投与することによって毛髪の成長を刺激するための方法
|
|
US20060280645A1
(en)
*
|
2005-06-02 |
2006-12-14 |
Scott Sellers |
Method for terminal sterilization of transdermal delivery devices
|
|
WO2006130868A1
(en)
*
|
2005-06-02 |
2006-12-07 |
Alza Corporation |
Method for terminal sterilization of transdermal delivery devices
|
|
US7815926B2
(en)
*
|
2005-07-11 |
2010-10-19 |
Musculoskeletal Transplant Foundation |
Implant for articular cartilage repair
|
|
JP5292533B2
(ja)
|
2005-08-26 |
2013-09-18 |
ジンマー・インコーポレイテッド |
インプラントおよび関節疾患の治療、置換および治療方法
|
|
CA2623106C
(en)
|
2005-09-19 |
2013-12-24 |
Histogenics Corporation |
Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
|
|
US20070083270A1
(en)
*
|
2005-10-12 |
2007-04-12 |
Leila Masinaei |
Orthopedic prosthetic devices containing compositions for repair of defects in osseous tissues
|
|
US7498041B2
(en)
*
|
2005-10-12 |
2009-03-03 |
Lifenet Health |
Composition for repair of defects in osseous tissues
|
|
US9005646B2
(en)
|
2005-10-12 |
2015-04-14 |
Lifenet Health |
Compositions for repair of defects in tissues, and methods of making the same
|
|
US20070088404A1
(en)
*
|
2005-10-19 |
2007-04-19 |
Allen Wyler |
Methods and systems for improving neural functioning, including cognitive functioning and neglect disorders
|
|
WO2007106581A2
(en)
*
|
2006-03-15 |
2007-09-20 |
Promethean Lifesciences, Inc. |
Preparation and storage of stable, antimicrobially active materials
|
|
US20100068245A1
(en)
*
|
2006-03-15 |
2010-03-18 |
Manders Christian D |
Preparation and storage of stable, biologically active materials
|
|
EP1852443A1
(de)
*
|
2006-05-05 |
2007-11-07 |
Leukocare AG |
Biokompatible dreidimensionale Matrix für die Immobilisierung von biologischen Substanzen
|
|
US7520108B2
(en)
|
2006-06-13 |
2009-04-21 |
Tetra Laval Holdings & Finance Sa |
Method of sterilizing packages
|
|
SE530589C2
(sv)
*
|
2006-12-11 |
2008-07-15 |
Tetra Laval Holdings & Finance |
Metod att bestråla föremål
|
|
US8048857B2
(en)
*
|
2006-12-19 |
2011-11-01 |
Warsaw Orthopedic, Inc. |
Flowable carrier compositions and methods of use
|
|
US8163549B2
(en)
|
2006-12-20 |
2012-04-24 |
Zimmer Orthobiologics, Inc. |
Method of obtaining viable small tissue particles and use for tissue repair
|
|
US20080154233A1
(en)
*
|
2006-12-20 |
2008-06-26 |
Zimmer Orthobiologics, Inc. |
Apparatus for delivering a biocompatible material to a surgical site and method of using same
|
|
US7718616B2
(en)
|
2006-12-21 |
2010-05-18 |
Zimmer Orthobiologics, Inc. |
Bone growth particles and osteoinductive composition thereof
|
|
US8435551B2
(en)
|
2007-03-06 |
2013-05-07 |
Musculoskeletal Transplant Foundation |
Cancellous construct with support ring for repair of osteochondral defects
|
|
EP2134297B1
(de)
*
|
2007-04-12 |
2017-03-08 |
Zimmer, Inc. |
Vorrichtung zur gewebereparatur
|
|
EP2058335B1
(de)
*
|
2007-11-07 |
2020-06-24 |
Leukocare Ag |
Biologisch verträgliche, dreidimensionale Matrix zur Immobilisierung von biologischen Substanzen
|
|
US20140031944A1
(en)
*
|
2008-03-18 |
2014-01-30 |
Yoh Sawatari |
Cylindrical graft and method for preparing a recipient site and implanting a cylindrical graft into alveolar jaw bone
|
|
US9616153B2
(en)
|
2008-04-17 |
2017-04-11 |
Warsaw Orthopedic, Inc. |
Rigid bone graft substitute
|
|
US20090263507A1
(en)
*
|
2008-04-18 |
2009-10-22 |
Warsaw Orthopedic, Inc. |
Biological markers and response to treatment for pain, inflammation, neuronal or vascular injury and methods of use
|
|
WO2010015259A2
(en)
*
|
2008-08-06 |
2010-02-11 |
Inmold Biosystems A/S |
Sterilisation of polymeric products comprising heat and radiation sensitive material
|
|
WO2010083051A2
(en)
*
|
2009-01-15 |
2010-07-22 |
ProChon Biotech, Ltd. |
Cartilage particle tissue mixtures optionally combined with a cancellous construct
|
|
US20100226959A1
(en)
*
|
2009-03-04 |
2010-09-09 |
Warsaw Orthopedic, Inc. |
Matrix that prolongs growth factor release
|
|
DE102009024616A1
(de)
|
2009-06-08 |
2010-12-23 |
Telos Gmbh |
Sterilisierbare Implantatbeschichtung und Verfahren zu deren Herstellung
|
|
WO2012068135A1
(en)
|
2010-11-15 |
2012-05-24 |
Zimmer Orthobiologics, Inc. |
Bone void fillers
|
|
US9168231B2
(en)
|
2010-12-05 |
2015-10-27 |
Nanonerve, Inc. |
Fibrous polymer scaffolds having diametrically patterned polymer fibers
|
|
US20140178343A1
(en)
|
2012-12-21 |
2014-06-26 |
Jian Q. Yao |
Supports and methods for promoting integration of cartilage tissue explants
|
|
AU2014205119B2
(en)
*
|
2013-01-13 |
2017-04-06 |
Arteriocyte Medical Systems, Inc. |
Oxygenated three-dimensional matrix for bone growth
|
|
US9572912B2
(en)
|
2013-04-19 |
2017-02-21 |
Theracell, Inc. |
Demineralized bone fibers having controlled geometry and shapes and methods thereof
|
|
WO2015088990A1
(en)
|
2013-12-09 |
2015-06-18 |
Durect Corporation |
Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
|
|
US10077420B2
(en)
|
2014-12-02 |
2018-09-18 |
Histogenics Corporation |
Cell and tissue culture container
|
|
US11052175B2
(en)
|
2015-08-19 |
2021-07-06 |
Musculoskeletal Transplant Foundation |
Cartilage-derived implants and methods of making and using same
|
|
WO2020158833A1
(ja)
*
|
2019-01-31 |
2020-08-06 |
セルメディシン株式会社 |
無機塩類タンパク複合医療機器
|
|
JP7883042B1
(ja)
*
|
2025-12-17 |
2026-06-30 |
株式会社Adeka |
コラーゲン含有材料及びその製造方法
|