ATE515268T1 - Verwendung von op-1 zur behandlung von knorpeldefekten - Google Patents
Verwendung von op-1 zur behandlung von knorpeldefektenInfo
- Publication number
- ATE515268T1 ATE515268T1 AT05753766T AT05753766T ATE515268T1 AT E515268 T1 ATE515268 T1 AT E515268T1 AT 05753766 T AT05753766 T AT 05753766T AT 05753766 T AT05753766 T AT 05753766T AT E515268 T1 ATE515268 T1 AT E515268T1
- Authority
- AT
- Austria
- Prior art keywords
- cartilage defects
- treat cartilage
- cartilage
- treat
- repairing
- Prior art date
Links
- 210000000845 cartilage Anatomy 0.000 title abstract 4
- 230000000921 morphogenic effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000001172 regenerating effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57442304P | 2004-05-25 | 2004-05-25 | |
| PCT/US2005/018020 WO2005115438A1 (en) | 2004-05-25 | 2005-05-24 | Use of morphogenic proteins for treating cartilage defects |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE515268T1 true ATE515268T1 (de) | 2011-07-15 |
Family
ID=34970831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05753766T ATE515268T1 (de) | 2004-05-25 | 2005-05-24 | Verwendung von op-1 zur behandlung von knorpeldefekten |
Country Status (7)
| Country | Link |
|---|---|
| EP (2) | EP1763362B1 (de) |
| JP (4) | JP5201987B2 (de) |
| AT (1) | ATE515268T1 (de) |
| AU (1) | AU2005247440B2 (de) |
| CA (1) | CA2567405A1 (de) |
| ES (1) | ES2369629T3 (de) |
| WO (1) | WO2005115438A1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7169405B2 (en) | 2003-08-06 | 2007-01-30 | Warsaw Orthopedic, Inc. | Methods and devices for the treatment of intervertebral discs |
| US20060194726A1 (en) * | 2004-05-25 | 2006-08-31 | Rueger David C | Methods of treating cartilage defects |
| US7879027B2 (en) | 2006-04-24 | 2011-02-01 | Warsaw Orthopedic, Inc. | Controlled release devices for fusion of osteal structures |
| US8642059B2 (en) | 2006-04-24 | 2014-02-04 | Warsaw Orthopedic, Inc. | Controlled release systems and methods for intervertebral discs |
| US8642060B2 (en) | 2006-04-24 | 2014-02-04 | Warsaw Orthopedic, Inc. | Controlled release systems and methods for osteal growth |
| US7771414B2 (en) | 2006-04-24 | 2010-08-10 | Warsaw Orthopedic, Inc. | Controlled release devices for therapeutic treatments of spinal discs |
| US20090298761A1 (en) * | 2006-05-17 | 2009-12-03 | Donald Engelman | Methods of treating cartilage defects using a soluble morphogenic protein complex |
| PL2081551T3 (pl) * | 2006-10-06 | 2013-06-28 | Scil Tech Gmbh | Wytworzenie wysuszonego rekonstytuowanego pęcherzyka do zastosowania farmaceutycznego |
| AU2007234612B2 (en) | 2006-12-14 | 2013-06-27 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein stabilization formulations |
| EP2120859B1 (de) * | 2006-12-21 | 2013-11-20 | Stryker Corporation | Formulierungen mit verzögerter freisetzung mit kristallen von bmp-7 |
| US8828941B2 (en) | 2007-02-23 | 2014-09-09 | Divya Diwan | Composition and method for the treatment or prevention of spinal disorders |
| US7678764B2 (en) | 2007-06-29 | 2010-03-16 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein formulations for use at elevated temperatures |
| CN101801405A (zh) | 2007-08-07 | 2010-08-11 | 先进科技及再生医学有限责任公司 | 包含于酸性水溶液中的gdf-5的蛋白质配方 |
| EP2254559B1 (de) * | 2008-02-08 | 2018-10-10 | Foresee Pharmaceuticals Co., Ltd. | Zusammensetzung zur verzögerten freisetzung von proteinen oder peptiden |
| JP5599778B2 (ja) | 2008-04-14 | 2014-10-01 | デピュイ・シンセス・プロダクツ・エルエルシー | 液体緩衝gdf−5製剤 |
| EP2396026A2 (de) | 2009-02-12 | 2011-12-21 | Stryker Corporation | Zusammensetzungen und verfahren für die minimal invasive systemische abgabe von proteinen einschliesslich mitglieder der tgf-superfamilie |
| EP2352750B1 (de) | 2009-09-17 | 2012-06-13 | Stryker Corporation | Puffer zur steuerung des ph-wertes knochenmorphogenetischer proteine |
| US9132207B2 (en) | 2009-10-27 | 2015-09-15 | Spine Wave, Inc. | Radiopaque injectable nucleus hydrogel compositions |
| CA2785038A1 (en) | 2009-12-22 | 2011-07-21 | Stryker Corporation | Bmp-7 variants with reduced immunogenicity |
| WO2017203331A1 (en) | 2016-05-27 | 2017-11-30 | Universität Bern | Composition and methods for bone tissue engineering |
Family Cites Families (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773319A (en) | 1971-12-16 | 1973-11-20 | Fabcor Ind Inc | Corrugated sheet inverting machine |
| IE52535B1 (en) | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
| US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| DE3218121A1 (de) | 1982-05-14 | 1983-11-17 | Leskovar, Peter, Dr.-Ing., 8000 München | Arzneimittel zur tumorbehandlung |
| US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| HUT35524A (en) | 1983-08-02 | 1985-07-29 | Hoechst Ag | Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance |
| US5013649A (en) | 1986-07-01 | 1991-05-07 | Genetics Institute, Inc. | DNA sequences encoding osteoinductive products |
| US5459047A (en) | 1986-07-01 | 1995-10-17 | Genetics Institute, Inc. | BMP-6 proteins |
| IL83003A (en) | 1986-07-01 | 1995-07-31 | Genetics Inst | Osteoinductive factors |
| US5266683A (en) | 1988-04-08 | 1993-11-30 | Stryker Corporation | Osteogenic proteins |
| US5324819A (en) | 1988-04-08 | 1994-06-28 | Stryker Corporation | Osteogenic proteins |
| US5354557A (en) | 1988-04-08 | 1994-10-11 | Stryker Corporation | Osteogenic devices |
| US5011691A (en) | 1988-08-15 | 1991-04-30 | Stryker Corporation | Osteogenic devices |
| JP3504259B2 (ja) * | 1989-03-28 | 2004-03-08 | ジェネティックス・インスチチュート・リミテッド・ライアビリティ・カンパニー | 骨誘導組成物 |
| ATE162223T1 (de) | 1989-03-28 | 1998-01-15 | Genetics Inst | Osteoinduktive zusammensetzungen |
| CA2082941A1 (en) | 1990-05-16 | 1991-11-17 | Rodney M. Hewick | Bone and cartilage inductive proteins |
| AU666291B2 (en) | 1990-06-15 | 1996-02-08 | Carnegie Institution Of Washington | Gdf-1 |
| CA2108770C (en) | 1991-06-25 | 2007-04-03 | John M. Wozney | Bmp-9 compositions |
| US6287816B1 (en) | 1991-06-25 | 2001-09-11 | Genetics Institute, Inc. | BMP-9 compositions |
| CA2129820C (en) | 1992-02-12 | 2003-06-17 | Helge Neidhardt | Dna sequences encoding novel growth/differentiation factors |
| WO1994010203A2 (en) | 1992-11-03 | 1994-05-11 | Creative Biomolecules, Inc. | Op-3-induced morphogenesis |
| WO1994015966A1 (en) | 1993-01-12 | 1994-07-21 | Johns Hopkins University School Of Medicine | Growth differentiation factor-9 |
| EP0690871A4 (de) | 1993-01-12 | 1999-10-20 | Univ Johns Hopkins Med | Wachstums-differenzierungsfaktor-5 |
| CA2157577C (en) | 1993-03-19 | 2009-11-17 | Se-Jin Lee | Growth differentiation factor-8 |
| EP0698094B1 (de) | 1993-05-12 | 2004-02-04 | Genetics Institute, LLC | Bmp-11 zusammensetzungen |
| ATE265529T1 (de) | 1993-05-12 | 2004-05-15 | Inst Genetics Llc | Bmp-10 zusammensetzungen |
| JPH09503903A (ja) | 1993-07-09 | 1997-04-22 | ザ ジョーンズ ホプキンス ユニバーシティー スクール オブ メディシン | 増殖分化因子−6 |
| JPH0788174A (ja) * | 1993-09-28 | 1995-04-04 | Yamanouchi Pharmaceut Co Ltd | 骨形成用移植体 |
| EP0725796A4 (de) | 1993-10-08 | 1999-12-01 | Univ Johns Hopkins | Wachstumsdifferenzierungsfaktor-10 |
| JP3300500B2 (ja) | 1993-10-12 | 2002-07-08 | 新日本製鐵株式会社 | 疲労強度、降伏強度および被削性に優れる熱間鍛造用鋼の製造方法 |
| DE4334646C1 (de) | 1993-10-12 | 1994-09-29 | Quinting Friedhelm | Durchsichtige Analog-Zeituhr |
| EP0733109B9 (de) | 1993-12-07 | 2006-07-05 | Genetics Institute, LLC | Bmp-12, bmp-13 und diese enthaltende sehne-induzierende zusammensetzungen |
| IL114397A0 (en) | 1994-07-01 | 1995-10-31 | Bioph Biotech Entw Pharm Gmbh | Growth/differentiation factor of the TGF-beta-family |
| DE69534468T2 (de) | 1994-07-08 | 2006-07-13 | The Johns Hopkins University School Of Medicine | Wachstums-differenzierungsfaktor-11 |
| WO1996014335A1 (en) | 1994-11-07 | 1996-05-17 | The Government Of The United States Of America, Asrepresented By The Secretary, Department Of Health And Human Services | Cartilage-derived morphogenetic proteins |
| US5635372A (en) | 1995-05-18 | 1997-06-03 | Genetics Institute, Inc. | BMP-15 compositions |
| US5902785A (en) * | 1995-06-06 | 1999-05-11 | Genetics Institute, Inc. | Cartilage induction by bone morphogenetic proteins |
| US5674292A (en) * | 1995-06-07 | 1997-10-07 | Stryker Corporation | Terminally sterilized osteogenic devices and preparation thereof |
| AU6267798A (en) * | 1997-02-07 | 1998-08-26 | Stryker Corporation | Matrix-free osteogenic devices, implants and methods of use thereof |
| US6027917A (en) | 1997-12-10 | 2000-02-22 | Genetics Institute, Inc. | Bone morphogenetic protein (BMP)-17 and BMP-18 compositions |
| JP2002520068A (ja) * | 1998-07-15 | 2002-07-09 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | 骨形態形成タンパク質 |
| US6958149B2 (en) * | 1998-10-06 | 2005-10-25 | Stryker Corporation | Repair of larynx, trachea, and other fibrocartilaginous tissues |
| MXPA01003538A (es) * | 1998-10-06 | 2005-09-08 | Rush Presbyterian St Luke | Metodo para el tratamiento de quimionucleolisis. |
| CZ20012782A3 (cs) * | 1999-02-01 | 2002-01-16 | Genetics Institute, Inc. | Prostředek pro hojení a náhradu kloubní chrupavky |
| DK1244388T3 (da) * | 1999-12-06 | 2007-05-14 | Warsaw Orthopedic Inc | Indretning til behandling af mellemhvirvelskiver |
| WO2002067978A1 (en) * | 2001-02-23 | 2002-09-06 | Wyeth | Chondrogenic potential of human bone marrow-derived cd105+ cells by bmp |
| MXPA04007124A (es) * | 2002-02-01 | 2004-10-29 | Omeros Corp | Composiciones y metodos para la inhibicion sistemica de la degradacion del cartilago. |
| WO2003077852A2 (en) * | 2002-03-12 | 2003-09-25 | Tissuegene, Inc. | CARTILAGE REGENERATION USING CHONDROCYTE AND TGF-β |
| EP1501357A4 (de) * | 2002-05-06 | 2009-10-21 | Genentech Inc | Verwendung von vegf für die behandlung von knochendefekten |
| JP2003325657A (ja) * | 2002-05-13 | 2003-11-18 | Hideki Yoshikawa | 関節軟骨形成用部材およびその製造方法、関節軟骨の再生または形成方法および培養方法ならびに移植用人工関節軟骨 |
| US8154581B2 (en) | 2002-10-15 | 2012-04-10 | Revolutionary Concepts, Inc. | Audio-video communication system for receiving person at entrance |
| WO2010117047A1 (ja) | 2009-04-10 | 2010-10-14 | 株式会社ニコン | 光学材料、光学素子、及びその製造方法 |
| JP2011211450A (ja) | 2010-03-30 | 2011-10-20 | Victor Co Of Japan Ltd | 立体映像表示装置、立体映像撮像装置および立体映像表示方法 |
| US9507084B2 (en) | 2010-12-03 | 2016-11-29 | Ofs Fitel, Llc | Single-mode, bend-compensated, large-mode-area optical fibers designed to accomodate simplified fabrication and tighter bends |
| US8743666B1 (en) | 2011-03-08 | 2014-06-03 | Western Digital Technologies, Inc. | Energy assisted magnetic recording medium capable of suppressing high DC readback noise |
| KR101851912B1 (ko) | 2012-06-07 | 2018-04-24 | 아사히 가세이 일렉트로닉스 가부시끼가이샤 | 위치 검출 장치 |
| US9298469B2 (en) | 2012-06-15 | 2016-03-29 | International Business Machines Corporation | Management of multiple nested transactions |
| US9405290B1 (en) | 2013-01-17 | 2016-08-02 | Kla-Tencor Corporation | Model for optical dispersion of high-K dielectrics including defects |
| JP6154215B2 (ja) | 2013-06-28 | 2017-06-28 | 株式会社日立国際電気 | 半導体装置の製造方法、基板処理装置およびプログラム |
| US9170581B2 (en) | 2013-09-30 | 2015-10-27 | Crown Equipment Limited | Industrial vehicles with overhead light based localization |
| JP6541301B2 (ja) | 2014-03-28 | 2019-07-10 | キヤノン株式会社 | ロボット装置、ロボット装置の制御方法、ロボット制御プログラム、及び記録媒体 |
| US9411440B2 (en) | 2014-08-22 | 2016-08-09 | Qualcomm Incorporated | Digital ultrasonic emitting base station |
| US9400685B1 (en) | 2015-01-30 | 2016-07-26 | Huawei Technologies Co., Ltd. | Dividing, scheduling, and parallel processing compiled sub-tasks on an asynchronous multi-core processor |
-
2005
- 2005-05-24 CA CA002567405A patent/CA2567405A1/en not_active Abandoned
- 2005-05-24 JP JP2007515221A patent/JP5201987B2/ja not_active Expired - Fee Related
- 2005-05-24 ES ES05753766T patent/ES2369629T3/es not_active Expired - Lifetime
- 2005-05-24 AU AU2005247440A patent/AU2005247440B2/en not_active Ceased
- 2005-05-24 AT AT05753766T patent/ATE515268T1/de not_active IP Right Cessation
- 2005-05-24 WO PCT/US2005/018020 patent/WO2005115438A1/en not_active Ceased
- 2005-05-24 EP EP05753766A patent/EP1763362B1/de not_active Expired - Lifetime
- 2005-05-24 EP EP10179674.6A patent/EP2298335B1/de not_active Expired - Lifetime
-
2011
- 2011-07-04 JP JP2011148712A patent/JP2011189200A/ja not_active Withdrawn
-
2013
- 2013-07-19 JP JP2013150201A patent/JP2013213067A/ja active Pending
-
2016
- 2016-01-04 JP JP2016000286A patent/JP2016047855A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ES2369629T3 (es) | 2011-12-02 |
| JP2013213067A (ja) | 2013-10-17 |
| EP2298335B1 (de) | 2014-09-03 |
| EP1763362B1 (de) | 2011-07-06 |
| JP5201987B2 (ja) | 2013-06-05 |
| EP2298335A1 (de) | 2011-03-23 |
| EP1763362A1 (de) | 2007-03-21 |
| JP2016047855A (ja) | 2016-04-07 |
| AU2005247440A1 (en) | 2005-12-08 |
| CA2567405A1 (en) | 2005-12-08 |
| JP2008500346A (ja) | 2008-01-10 |
| JP2011189200A (ja) | 2011-09-29 |
| WO2005115438B1 (en) | 2006-01-05 |
| WO2005115438A1 (en) | 2005-12-08 |
| AU2005247440B2 (en) | 2011-09-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1916964A4 (de) | Implantate und verfahren zur behebung, ersetzung und behandlung von gelenkkrankheiten | |
| DE60137430D1 (de) | Gewebeimplant zur wiederherstellung von knorpelgewebe | |
| DE602006018583D1 (de) | Verfahren und zusammensetzung zur behandlung von peripheren gefässkrankheiten | |
| ATE497778T1 (de) | Lactoferrin-zusammensetzungen und verfahren zur behandlung von diabetischen ulcus | |
| DE602004014117D1 (de) | Thiazole zur verwendung als inhibitoren von protein-kinasen | |
| DK1615952T3 (da) | Fremgangsmåder til behandling af betændelsestilstande med specifikke, til humant angiopoietin-2-bindende midler | |
| ATE493433T1 (de) | Neue zusammensetzung und verfahren zur behandlung von immunerkrankungen | |
| DE602005019144D1 (de) | Verfahren zur schmerzbehandlung in knochenkrebs du | |
| EP1701664A4 (de) | System und verfahren zur behandlung von gewebe | |
| EP1896083A4 (de) | Verfahren zur behandlung von pompe-krankheit mit 1-desoxynojirimycin und derivaten | |
| ATE404188T1 (de) | Verfahren und zusammensetzungen zur behandlung von augenerkrankungen mit retinyl-derivaten | |
| EP2207595A4 (de) | System und verfahren zur behandlung von tierischem gewebe mithilfe von laserlicht | |
| DE602005011656D1 (de) | Verfahren zur behandlung von dickdarmkrebs mit botulinum neurotoxin | |
| DE60325770D1 (de) | Verwendung von rimexolon zur behandlung von augentrockenheit | |
| DE60335293D1 (de) | Pyrrolopyridazin-verbindungen und verwendungsverfahren dafür zur behandlung von proliferativen erkrankungen | |
| DE60328517D1 (de) | Neue verwendung von lycopin zur behandlung von erkrankungen im zusammenhang mit androgenwirkung | |
| ATE308880T1 (de) | Verfahren zur erhöhung der biologischen effektivität von zusammensetzungen zur pflanzenbehandlung | |
| ATE439863T1 (de) | Ophthalmische zusammensetzungen von parasympathischen stimulantia und entzündungshemmer zur verwendung bei der behandlung von presbyopie | |
| DE602004031134D1 (de) | Pharmazeutische zusammensetzungen und verfahren zur verwendung von levodopa und carbidopa | |
| ATE540129T1 (de) | Target zur therapie kognitiver behinderungen | |
| ATE485517T1 (de) | Verfahren zur identifizierung von polypeptid- targets | |
| DE602004017283D1 (de) | Verfahren zur behandlung von schwerer herzinsuffizienz und medikament dafür | |
| DE60136748D1 (de) | Verfahren und zusammensetzungen zur behandlung von augenerkrankungen | |
| EP1499190A4 (de) | Verfahren zur behandlung von lebererkrankungen und leberschäden mit wachstumshormon und foxm1b | |
| DE60206289D1 (de) | Verwendung von bibn4096 in kombination mit anderen migränemitteln zur behandlung von migräne |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |