ATE350387T1 - Verfahren zur reinigung von molekülen unter verwendung von unverzweigten alkyldiolen mit einständigen hydroxylgruppen - Google Patents

Verfahren zur reinigung von molekülen unter verwendung von unverzweigten alkyldiolen mit einständigen hydroxylgruppen

Info

Publication number: ATE350387T1
Authority: AT; Austria
Prior art keywords: alkyldiols; unbranched; hydroxyl groups; single hydroxyl; molecules
Prior art date: 2001-03-19

Application number

AT02753569T

Other languages

English (en)

Inventor

Terry Allen Hauser

Kirk James Hayenga

Original Assignee

Organon Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-03-19

Filing date

2002-03-14

Publication date

2007-01-15

2002-03-14 Application filed by Organon Nv filed Critical Organon Nv

2007-01-15 Application granted granted Critical

2007-01-15 Publication of ATE350387T1 publication Critical patent/ATE350387T1/de

Links

238000000034 method Methods 0.000 title abstract 2
-1 HYDROXYL GROUPS Chemical group 0.000 title 1
229940043375 1,5-pentanediol Drugs 0.000 abstract 1
ALQSHHUCVQOPAS-UHFFFAOYSA-N Pentane-1,5-diol Chemical compound OCCCCCO ALQSHHUCVQOPAS-UHFFFAOYSA-N 0.000 abstract 1
SXCBDZAEHILGLM-UHFFFAOYSA-N heptane-1,7-diol Chemical compound OCCCCCCCO SXCBDZAEHILGLM-UHFFFAOYSA-N 0.000 abstract 1
XXMIOPMDWAUFGU-UHFFFAOYSA-N hexane-1,6-diol Chemical compound OCCCCCCO XXMIOPMDWAUFGU-UHFFFAOYSA-N 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
238000000746 purification Methods 0.000 abstract 1
238000004366 reverse phase liquid chromatography Methods 0.000 abstract 1
238000004007 reversed phase HPLC Methods 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/70—Enkephalins
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/32—Bonded phase chromatography
- B01D15/325—Reversed phase
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
- B01D15/424—Elution mode
- B01D15/426—Specific type of solvent
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/68—Melanocyte-stimulating hormone [MSH]
- C07K14/685—Alpha-melanotropin
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Endocrinology (AREA)
Analytical Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Peptides Or Proteins (AREA)
Detergent Compositions (AREA)

AT02753569T 2001-03-19 2002-03-14 Verfahren zur reinigung von molekülen unter verwendung von unverzweigten alkyldiolen mit einständigen hydroxylgruppen ATE350387T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US09/813,093 US6966992B2 (en)	2001-03-19	2001-03-19	Method of purification of molecules using unbranched terminal alkyldiols

Publications (1)

Publication Number	Publication Date
ATE350387T1 true ATE350387T1 (de)	2007-01-15

Family

ID=25211429

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02753569T ATE350387T1 (de)	2001-03-19	2002-03-14	Verfahren zur reinigung von molekülen unter verwendung von unverzweigten alkyldiolen mit einständigen hydroxylgruppen

Country Status (6)

Country	Link
US (1)	US6966992B2 (de)
EP (1)	EP1373302B1 (de)
AT (1)	ATE350387T1 (de)
DE (1)	DE60217312T2 (de)
ES (1)	ES2278939T3 (de)
WO (1)	WO2002074791A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1638990B1 (de) *	2003-06-24	2009-04-08	N.V. Organon	Abtrennung von lipopolysacchariden aus lipopolysaccharidkomplexen mit hilfe von nicht-entzündbaren lösungsmitteln
US7413658B2 (en) *	2003-11-21	2008-08-19	Akzo Nobel N.V.	Separation method
US20080085562A1 (en) *	2006-10-10	2008-04-10	Idexx Laboratories, Inc.	Detection of gadolinium chelates
US20080085563A1 (en) *	2006-10-10	2008-04-10	Idexx Laboratories, Inc.	Detection of Gadolinium Chelates
US8580935B2 (en)	2007-02-26	2013-11-12	Alltech Associates, Inc.	Ultra-fast chromatography
MY195756A (en)	2012-09-17	2023-02-09	Grace W R & Co	Functionalized Particulate Support Material and Methods of Making and Using the Same
IN2015DN02055A (de)	2012-09-17	2015-08-14	Grace W R & Co
EP3094390B1 (de)	2014-01-16	2021-07-07	W.R. Grace & CO. - CONN.	Affinitätschromatographiemedien und chromatographievorrichtungen
SG10201911134QA (en)	2015-06-05	2020-01-30	Grace W R & Co	Adsorbent bioprocessing clarification agents and methods of making and using the same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ212523A (en) *	1985-06-24	1989-01-06	Univ Massey	Mobile phase for purification of proteins by high performance liquid chromatography
DD285113A5 (de) *	1989-06-21	1990-12-05	Akad Wissenschaften Ddr	Verfahren zur gewinnung von reinem menschlichen wachstumshormon (hgh)
WO1991015502A1 (fr) *	1990-03-30	1991-10-17	Shiseido Company, Ltd.	Procede de purification de polypeptide
US5693769A (en) *	1991-12-13	1997-12-02	Transcell Technologies, Inc.	Glycosylated steroid derivatives for transport across biological membranes and process for making and using same
ES2364774T3 (es) *	1994-02-24	2011-09-14	HENKEL AG & CO. KGAA	Enzimas mejoradas y detergentes que las contienen.
US6008041A (en) *	1996-05-08	1999-12-28	Eli Lilly And Company	Bovine dipeptidylaminopeptidase 1
US5994511A (en) *	1997-07-02	1999-11-30	Genentech, Inc.	Anti-IgE antibodies and methods of improving polypeptides
DE19836213A1 (de) *	1998-08-11	2000-02-24	Gerhard Harry Scholz	Verfahren zur Elution von Biomolekülen von Chromatographie-Materialien
US6437101B1 (en) *	1999-05-07	2002-08-20	Akzo Nobel N.V.	Methods for protein purification using aqueous two-phase extraction

2001
- 2001-03-19 US US09/813,093 patent/US6966992B2/en not_active Expired - Lifetime
2002
- 2002-03-14 AT AT02753569T patent/ATE350387T1/de not_active IP Right Cessation
- 2002-03-14 EP EP02753569A patent/EP1373302B1/de not_active Expired - Lifetime
- 2002-03-14 ES ES02753569T patent/ES2278939T3/es not_active Expired - Lifetime
- 2002-03-14 DE DE60217312T patent/DE60217312T2/de not_active Expired - Lifetime
- 2002-03-14 WO PCT/EP2002/003021 patent/WO2002074791A1/en not_active Ceased

Also Published As

Publication number	Publication date
WO2002074791A1 (en)	2002-09-26
EP1373302A1 (de)	2004-01-02
EP1373302B1 (de)	2007-01-03
US20020183483A1 (en)	2002-12-05
US6966992B2 (en)	2005-11-22
ES2278939T3 (es)	2007-08-16
WO2002074791A8 (en)	2004-05-21
DE60217312T2 (de)	2007-07-12
DE60217312D1 (de)	2007-02-15

Legal Events

Date	Code	Title	Description
2007-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

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