ATE352549T1 - Verfahren zur herstellung von desloratadin - Google Patents
Verfahren zur herstellung von desloratadinInfo
- Publication number
- ATE352549T1 ATE352549T1 AT02807860T AT02807860T ATE352549T1 AT E352549 T1 ATE352549 T1 AT E352549T1 AT 02807860 T AT02807860 T AT 02807860T AT 02807860 T AT02807860 T AT 02807860T AT E352549 T1 ATE352549 T1 AT E352549T1
- Authority
- AT
- Austria
- Prior art keywords
- desloratadine
- producing
- loratadine
- isolating
- reacted
- Prior art date
Links
- JAUOIFJMECXRGI-UHFFFAOYSA-N Neoclaritin Chemical compound C=1C(Cl)=CC=C2C=1CCC1=CC=CN=C1C2=C1CCNCC1 JAUOIFJMECXRGI-UHFFFAOYSA-N 0.000 title abstract 3
- 229960001271 desloratadine Drugs 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 150000007529 inorganic bases Chemical class 0.000 abstract 1
- 229960003088 loratadine Drugs 0.000 abstract 1
- JCCNYMKQOSZNPW-UHFFFAOYSA-N loratadine Chemical compound C1CN(C(=O)OCC)CCC1=C1C2=NC=CC=C2CCC2=CC(Cl)=CC=C21 JCCNYMKQOSZNPW-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IN2002/000193 WO2004029039A1 (en) | 2002-09-24 | 2002-09-24 | An improved process for the production of desloratadine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE352549T1 true ATE352549T1 (de) | 2007-02-15 |
Family
ID=32040229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02807860T ATE352549T1 (de) | 2002-09-24 | 2002-09-24 | Verfahren zur herstellung von desloratadin |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20060100435A1 (de) |
| EP (1) | EP1542986B1 (de) |
| AT (1) | ATE352549T1 (de) |
| AU (1) | AU2002334383A1 (de) |
| CA (1) | CA2499125C (de) |
| DE (1) | DE60217934T2 (de) |
| WO (1) | WO2004029039A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ200798A3 (cs) * | 2004-07-07 | 2007-06-20 | Egis Gyogyszergyár Nyrt. | Nový pseudopolymorf desloratadinu vytvorený s oxidem uhlicitým |
| WO2008032136A1 (en) * | 2006-09-13 | 2008-03-20 | Orchid Chemicals And Pharmaceuticals Limited | An improved process for the preparation of desloratadine |
| WO2008107777A2 (en) * | 2007-03-06 | 2008-09-12 | Cadila Pharmaceuticals Limited | Improved method for the preparation of desloratadine with reduced levels of organic solvents |
| WO2010109442A1 (en) * | 2009-03-26 | 2010-09-30 | Ranbaxy Laboratories Limited | Process for the preparation of desloratadine |
| CN102875527B (zh) * | 2012-10-11 | 2014-05-07 | 江苏德峰药业有限公司 | 一种地氯雷他定的制备方法 |
| EP2727592A1 (de) | 2012-11-05 | 2014-05-07 | Kücükgüzel, Sükriye Güniz | Kombination aus Desloratadin und Paracetamol |
| CN104961724B (zh) * | 2015-06-08 | 2018-01-30 | 惠州信立泰药业有限公司 | 一种获得高纯度地氯雷他定的先进生产工艺 |
| EP3371193A4 (de) | 2015-10-12 | 2019-03-20 | Noramco, Inc. | Verfahren zur herstellung von (s)-2-((4r,4as, 6r,7ar,12bs)-7,9-dimethoxy-1,2,3,4,5,6,7,7a-octahydro-4a,7-ethano-4, 12-methanobenzofuro[3,2-e]isochinolin-6-yl)-3,3-dimethylbutan-2-ol |
| CN109020950A (zh) * | 2017-06-09 | 2018-12-18 | 浙江普利药业有限公司 | 一种地氯雷他定制备工艺 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4826853A (en) * | 1986-10-31 | 1989-05-02 | Schering Corporation | 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use |
| EP0723539B1 (de) * | 1993-10-15 | 2001-12-12 | Schering Corporation | Tricyclische sulfonamide-derivate zur inhibierung der g-protein funktion und fur die bekandlung von proliferativen erkrantungen |
| US5595997A (en) * | 1994-12-30 | 1997-01-21 | Sepracor Inc. | Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine |
| IL117798A (en) * | 1995-04-07 | 2001-11-25 | Schering Plough Corp | Tricyclic compounds useful for inhibiting the function of protein - G and for the treatment of malignant diseases, and pharmaceutical preparations containing them |
| US5925648A (en) * | 1997-07-29 | 1999-07-20 | Schering Corporation | Tricyclic N-cyanoimines useful as inhibitors of a farnesyl-protein transferase |
-
2002
- 2002-09-24 CA CA2499125A patent/CA2499125C/en not_active Expired - Lifetime
- 2002-09-24 AT AT02807860T patent/ATE352549T1/de not_active IP Right Cessation
- 2002-09-24 US US10/529,008 patent/US20060100435A1/en not_active Abandoned
- 2002-09-24 EP EP02807860A patent/EP1542986B1/de not_active Expired - Lifetime
- 2002-09-24 WO PCT/IN2002/000193 patent/WO2004029039A1/en not_active Ceased
- 2002-09-24 DE DE60217934T patent/DE60217934T2/de not_active Expired - Lifetime
- 2002-09-24 AU AU2002334383A patent/AU2002334383A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2499125A1 (en) | 2004-04-08 |
| EP1542986A1 (de) | 2005-06-22 |
| WO2004029039A1 (en) | 2004-04-08 |
| DE60217934D1 (de) | 2007-03-15 |
| DE60217934T2 (de) | 2007-05-24 |
| AU2002334383A1 (en) | 2004-04-19 |
| EP1542986B1 (de) | 2007-01-24 |
| CA2499125C (en) | 2010-12-14 |
| US20060100435A1 (en) | 2006-05-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE425136T1 (de) | Verfahren zur herstellung substituierter 3-aryl- butyl-aminverbindungen | |
| DE60203569D1 (de) | Verfahren zur Herstellung von Methanol | |
| DE60329527D1 (de) | Verfahren zur herstellung von photochromischen kontaktlinsen | |
| DE60217934D1 (de) | Verfahren zur herstellung von desloratadin | |
| ATE391115T1 (de) | Verfahren zur herstellung von diketenacetalen | |
| DE60105314D1 (de) | Verfahren zur herstellung von taxanderivaten | |
| DE60105141D1 (de) | Verfahren zur Herstellung einer organischen Dünnschicht | |
| ATE478105T1 (de) | Elektroaktiver komplex, elektroaktive sonde und verfahren zur herstellung | |
| ATE489352T1 (de) | Verfahren zur herstellung von brenztraubensäure | |
| ATE280769T1 (de) | Verfahren zur herstellung von vitronectin- rezeptorantagonisten | |
| ATE386027T1 (de) | Verfahren zur herstellung von valsartan | |
| DE50103009D1 (de) | Verfahren zur herstellung von 2-alkyl-3-chlorphenolen | |
| DE60331302D1 (de) | Verfahren zur herstellung von dichtungen | |
| ATE326545T1 (de) | Verfahren zur herstellung von d- oder l-menthol | |
| UA91153C2 (ru) | Способ получения формы и венлафаксина гидрохлорида | |
| ATE425143T1 (de) | Verfahren zur herstellung von indolen | |
| ATE233822T1 (de) | Verfahren zur stereoselektiven herstellung von substituierten cyclohexylcyanhydrinen | |
| ATE297404T1 (de) | Verbessertes verfahren zur herstellung von bisphosphiten | |
| DE60123504D1 (de) | Verfahren zur Herstellung von sauerstoffenthaltendem Brennstoff | |
| ATE537160T1 (de) | Verfahren zur herstellung von 14beta- hydroxybaccatin-iii-1,14-carbonat | |
| ATE466847T1 (de) | Verfahren zur herstellung von 14-beta- hydroxybaccatin-iii-1,14-carbonat | |
| ATE297478T1 (de) | Verfahren zur herstellung von orthocarbonsäuretrialkylestern | |
| ATE458723T1 (de) | Verfahren zur herstellung von 4,6-dichlor-5- fluorpyrimidin | |
| ATE387434T1 (de) | Verfahren zur herstellung von mintlacton | |
| ATE378340T1 (de) | Verfahren zur herstellung von 2,6-dihalogenpurin |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |