ATE353367T1 - Group b streptococcus proteine und deren verwendung - Google Patents

Group b streptococcus proteine und deren verwendung

Info

Publication number
ATE353367T1
ATE353367T1 AT99962422T AT99962422T ATE353367T1 AT E353367 T1 ATE353367 T1 AT E353367T1 AT 99962422 T AT99962422 T AT 99962422T AT 99962422 T AT99962422 T AT 99962422T AT E353367 T1 ATE353367 T1 AT E353367T1
Authority
AT
Austria
Prior art keywords
group
streptococcus proteins
streptococcus
proteins
Prior art date
Application number
AT99962422T
Other languages
English (en)
Inventor
Martin John Glenton Hughes
J D Santangelo
Jonathan Douglas Lane
Paul Everest
Robert Feldman
Joanne Christine Moore
Rebecca Kerry Wilson
Richard James Dobson
Gordon Dougan
Original Assignee
Microscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9828352.6A external-priority patent/GB9828352D0/en
Priority claimed from GBGB9828354.2A external-priority patent/GB9828354D0/en
Priority claimed from GBGB9828353.4A external-priority patent/GB9828353D0/en
Priority claimed from GBGB9828350.0A external-priority patent/GB9828350D0/en
Priority claimed from GBGB9828345.0A external-priority patent/GB9828345D0/en
Priority claimed from GBGB9828357.5A external-priority patent/GB9828357D0/en
Priority claimed from GBGB9828349.2A external-priority patent/GB9828349D0/en
Priority claimed from GBGB9828355.9A external-priority patent/GB9828355D0/en
Priority claimed from GBGB9828356.7A external-priority patent/GB9828356D0/en
Priority claimed from GBGB9828359.1A external-priority patent/GB9828359D0/en
Priority claimed from GBGB9900085.3A external-priority patent/GB9900085D0/en
Priority claimed from GBGB9900084.6A external-priority patent/GB9900084D0/en
Priority claimed from GBGB9900083.8A external-priority patent/GB9900083D0/en
Priority claimed from GBGB9900086.1A external-priority patent/GB9900086D0/en
Priority claimed from GBGB9900082.0A external-priority patent/GB9900082D0/en
Priority claimed from GBGB9901916.8A external-priority patent/GB9901916D0/en
Priority claimed from GBGB9901922.6A external-priority patent/GB9901922D0/en
Application filed by Microscience Ltd filed Critical Microscience Ltd
Application granted granted Critical
Publication of ATE353367T1 publication Critical patent/ATE353367T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56944—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
AT99962422T 1998-12-22 1999-12-22 Group b streptococcus proteine und deren verwendung ATE353367T1 (de)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
GBGB9828350.0A GB9828350D0 (en) 1998-12-22 1998-12-22 Protein and compositions containing it
GBGB9828345.0A GB9828345D0 (en) 1998-12-22 1998-12-22 Protein and compositions containing it
GBGB9828357.5A GB9828357D0 (en) 1998-12-22 1998-12-22 Protein and compositions containing it
GBGB9828349.2A GB9828349D0 (en) 1998-12-22 1998-12-22 Protein and compositions containing it
GBGB9828355.9A GB9828355D0 (en) 1998-12-22 1998-12-22 Protein and compositions containing it
GBGB9828353.4A GB9828353D0 (en) 1998-12-22 1998-12-22 Protein and compositions containig it
GBGB9828356.7A GB9828356D0 (en) 1998-12-22 1998-12-22 Protein and compositions containing it
GBGB9828352.6A GB9828352D0 (en) 1998-12-22 1998-12-22 Protein and compositions containing it
GBGB9828359.1A GB9828359D0 (en) 1998-12-22 1998-12-22 Protein and compositions containing it
GBGB9828354.2A GB9828354D0 (en) 1998-12-22 1998-12-22 Protein and compositions containing it
GBGB9900085.3A GB9900085D0 (en) 1999-01-04 1999-01-04 Protein and compositions containing it
GBGB9900084.6A GB9900084D0 (en) 1999-01-04 1999-01-04 Protein and compositions containing it
GBGB9900083.8A GB9900083D0 (en) 1999-01-04 1999-01-04 Protein and compositions containing it
GBGB9900086.1A GB9900086D0 (en) 1999-01-04 1999-01-04 Protein and compositions containing it
GBGB9900082.0A GB9900082D0 (en) 1999-01-04 1999-01-04 Protein and compositions containing it
GBGB9901916.8A GB9901916D0 (en) 1999-01-28 1999-01-28 Protein and compositions containing it
GBGB9901922.6A GB9901922D0 (en) 1999-01-28 1999-01-28 Protein and compositions containing it

Publications (1)

Publication Number Publication Date
ATE353367T1 true ATE353367T1 (de) 2007-02-15

Family

ID=27585888

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99962422T ATE353367T1 (de) 1998-12-22 1999-12-22 Group b streptococcus proteine und deren verwendung

Country Status (22)

Country Link
US (3) US6812021B1 (de)
EP (3) EP2105504A3 (de)
JP (1) JP2002533083A (de)
KR (3) KR100790653B1 (de)
CN (1) CN101066447A (de)
AP (1) AP1502A (de)
AT (1) ATE353367T1 (de)
AU (1) AU776735B2 (de)
CA (1) CA2354135A1 (de)
CY (1) CY1106559T1 (de)
CZ (1) CZ20012172A3 (de)
DK (1) DK1141308T3 (de)
EA (1) EA004444B1 (de)
ES (1) ES2281977T3 (de)
HU (1) HUP0104825A3 (de)
NO (1) NO20013102L (de)
NZ (3) NZ512297A (de)
OA (1) OA11734A (de)
PL (1) PL201887B1 (de)
PT (1) PT1141308E (de)
SI (1) SI1141308T1 (de)
WO (1) WO2000037646A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6890539B2 (en) 1998-12-22 2005-05-10 Microscience, Ltd. Genes and proteins, and their use
SI1140994T1 (sl) * 1998-12-22 2005-12-31 Microscience Ltd Proteini zunanje povrsine, njihovi geni in njihova uporaba
US6812021B1 (en) * 1998-12-22 2004-11-02 Microscience Limited Genes and proteins and their use
GB0105922D0 (en) * 2001-03-09 2001-04-25 Microscience Ltd Genes and proteins, and their use
EP1360324A2 (de) 2000-08-31 2003-11-12 Mayo Foundation For Medical Education And Research Nachweis von varicella-zoster-virus
GB0021977D0 (en) 2000-09-07 2000-10-25 Pyrosequencing Ab Method of sequencing DNA
US7691571B2 (en) 2001-01-31 2010-04-06 Mayo Foundation For Medical Education And Research Detection of bordetella
US7074598B2 (en) 2002-09-25 2006-07-11 Mayo Foundation For Medical Education And Research Detection of vancomycin-resistant enterococcus spp.
US7365176B2 (en) 2002-09-26 2008-04-29 Mayo Foundation For Medical Education And Research Detection of Epstein-Barr virus
CA2507711A1 (en) * 2002-12-02 2004-06-17 Biosynexus Incorporated Wall teichoic acid as a target for anti-staphylococcal therapies and vaccines
US7427475B2 (en) * 2003-11-18 2008-09-23 Mayo Foundation For Medical Education And Research Detection of group B streptococcus
EP2104512A2 (de) * 2006-12-21 2009-09-30 Emergent Product Development UK Limited Streptokokkenproteine und deren verwendung bei der impfung
US10114982B2 (en) 2012-05-18 2018-10-30 Tata Consultancy Services Limited Method and system for determining and implementing a viable containment design of a data center
CN106822885B (zh) 2017-02-16 2020-06-30 清华大学 肺炎链球菌疫苗

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5328996A (en) 1989-03-29 1994-07-12 University Of Florida Research Foundation, Inc. Bacterial plasmin receptors as fibrinolytic agents
CA2127550A1 (en) 1992-01-08 1993-07-22 Vincent Fischetti Multifunctional surface protein of streptococci
WO1994021685A1 (en) * 1993-03-19 1994-09-29 Gunnar Lindahl Protein rib, a cell surface protein that confers immunity to many strains of the group b streptococcus; process for purification of the protein, reagent kit and pharmaceutical composition
US6015889A (en) 1993-03-19 2000-01-18 Gunnar Lindahl Protein rib, a cell surface protein that confers immunity to many strains of the group B streptococcus: process for purification of the protein, reagent kit and pharmaceutical composition
US5807978A (en) * 1995-06-07 1998-09-15 Kokolus; William J. Immunogenic peptides of prostate specific antigen
PT942983E (pt) 1996-10-31 2007-02-28 Human Genome Sciences Inc Antigénios e vacinas de streptococcus pneumoniae
US7196164B2 (en) 1997-07-08 2007-03-27 Human Genome Sciences, Inc. Secreted protein HHTLF25
US6800744B1 (en) 1997-07-02 2004-10-05 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
US7081530B1 (en) * 1997-07-02 2006-07-25 sanofi pasteur limitée Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
US6380370B1 (en) 1997-08-14 2002-04-30 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics
WO1999042588A2 (en) 1998-02-20 1999-08-26 Biochem Pharma Inc. Group b streptococcus antigens
US6248329B1 (en) * 1998-06-01 2001-06-19 Ramaswamy Chandrashekar Parasitic helminth cuticlin nucleic acid molecules and uses thereof
CN1247262C (zh) 1998-07-14 2006-03-29 惠氏控股有限公司 含有单磷酸脂a的佐剂和疫苗组合物
CA2337102A1 (en) * 1998-07-27 2000-02-10 Richard William Falla Le Page Nucleic acids and proteins from group b streptococcus
NZ511224A (en) 1998-10-30 2003-10-31 Janssen Pharmaceutica Nv The use of the pCal retrotransposon in methods of gene disruption or altered expression in yeast or fungus
AU1818200A (en) 1998-11-05 2000-05-22 Daniel Carucci Chromosome 2 sequence of the human malaria parasite (plasmodium falciparum) and proteins of said chromosome useful in anti-malarial vaccines and diagnostic reagents
US6890539B2 (en) 1998-12-22 2005-05-10 Microscience, Ltd. Genes and proteins, and their use
US6812021B1 (en) 1998-12-22 2004-11-02 Microscience Limited Genes and proteins and their use
SI1140994T1 (sl) 1998-12-22 2005-12-31 Microscience Ltd Proteini zunanje povrsine, njihovi geni in njihova uporaba
WO2000061621A2 (en) 1999-04-09 2000-10-19 Heska Corporation Flea head, nerve cord, hindgut and malpighian tubule nucleic acid molecules, proteins and uses thereof
US6605709B1 (en) 1999-04-09 2003-08-12 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Proteus mirabilis for diagnostics and therapeutics
GB9921125D0 (en) 1999-09-07 1999-11-10 Microbial Technics Limited Proteins
AU1478301A (en) 1999-11-09 2001-06-06 Glaxo Group Limited Staphylococcus epidermidis nucleic acids and proteins
JP2004507217A (ja) 2000-04-11 2004-03-11 アンスティテュ・パストゥール リステリア菌ゲノム、ポリペプチドおよびその使用
US6974667B2 (en) 2000-06-14 2005-12-13 Gene Logic, Inc. Gene expression profiles in liver cancer
US7939087B2 (en) 2000-10-27 2011-05-10 Novartis Vaccines And Diagnostics, Inc. Nucleic acids and proteins from Streptococcus groups A & B
WO2002077183A2 (en) 2001-03-21 2002-10-03 Elitra Pharmaceuticals, Inc. Identification of essential genes in microorganisms
GB0107661D0 (en) 2001-03-27 2001-05-16 Chiron Spa Staphylococcus aureus
GB0107658D0 (en) 2001-03-27 2001-05-16 Chiron Spa Streptococcus pneumoniae
MXPA03009415A (es) 2001-04-16 2004-01-29 Wyeth Corp ESTRUCTURAS NOVEDOSAS DE LECTURA ABIERTA DE STREPTOCOCCUS PNEUMONIAE QUE CODIFICAN ANTIGENOS DE POLIPePTIDOS Y USOS DE LAS MISMAS.
EP2545937A1 (de) 2001-06-05 2013-01-16 The Regents Of The University Of Michigan Nanoemulsionsimpfstoffe
WO2003009869A1 (en) 2001-07-26 2003-02-06 Chiron Srl. Vaccines comprising aluminium adjuvants and histidine
GB0210128D0 (en) 2002-05-02 2002-06-12 Chiron Spa Nucleic acids and proteins from streptococcus groups A & B
WO2004041157A2 (en) 2002-09-13 2004-05-21 Chiron Corporation Group b streptococcus vaccine
CN101864431A (zh) 2003-05-07 2010-10-20 英特塞尔股份公司 无乳链球菌抗原ⅰ和ⅱ
EP1663303B1 (de) 2003-09-15 2011-05-04 Novartis Vaccines and Diagnostics, Inc. Immunogene zusammensetzungen für streptococcus agalactiae
AU2005335216A1 (en) 2004-10-05 2007-02-15 Wyeth Probe arrays for detecting multiple strains of different species
AU2005319174A1 (en) 2004-12-22 2006-06-29 J. Craig Venter Institute, Inc. Group B Streptococcus

Also Published As

Publication number Publication date
US20080181908A1 (en) 2008-07-31
ES2281977T3 (es) 2007-10-01
SI1141308T1 (sl) 2007-08-31
HUP0104825A2 (hu) 2002-04-29
CZ20012172A3 (cs) 2001-11-14
AP1502A (en) 2005-12-20
KR20080050550A (ko) 2008-06-09
EP1757696A2 (de) 2007-02-28
NZ512297A (en) 2003-12-19
HK1039353A1 (en) 2002-04-19
PL201887B1 (pl) 2009-05-29
PL349320A1 (en) 2002-07-15
EP2105504A3 (de) 2010-01-06
AU1878000A (en) 2000-07-12
US7419672B2 (en) 2008-09-02
AU776735B2 (en) 2004-09-23
NO20013102D0 (no) 2001-06-21
KR20070101197A (ko) 2007-10-16
KR20010089844A (ko) 2001-10-11
OA11734A (en) 2005-05-12
EP2105504A2 (de) 2009-09-30
US6812021B1 (en) 2004-11-02
WO2000037646A2 (en) 2000-06-29
JP2002533083A (ja) 2002-10-08
CY1106559T1 (el) 2012-01-25
NZ526879A (en) 2004-12-24
AP2001002189A0 (en) 2001-06-30
DK1141308T3 (da) 2007-06-04
US20090274717A1 (en) 2009-11-05
CN101066447A (zh) 2007-11-07
PT1141308E (pt) 2007-05-31
EP1141308A2 (de) 2001-10-10
HUP0104825A3 (en) 2008-04-28
NO20013102L (no) 2001-08-10
EP1757696A3 (de) 2008-10-29
CA2354135A1 (en) 2000-06-29
EP1141308B1 (de) 2007-02-07
EA200100700A1 (ru) 2001-12-24
WO2000037646A3 (en) 2000-10-26
EA004444B1 (ru) 2004-04-29
NZ535122A (en) 2006-04-28
KR100790653B1 (ko) 2007-12-31

Similar Documents

Publication Publication Date Title
ATE443719T1 (de) Interleukin-18 bindende proteine, deren herstellung und verwendung
DE69738197D1 (de) Azolotriazine und pyrimidine
DE69943335D1 (de) Ionenleitende matrizen und deren verwendung
EP0790826A4 (de) Dyhydropyrimidine und deren verwendungen
DE69622148D1 (de) Chinazozin derivate und deren verwendung
DE69826007D1 (de) Tetrafluorethylencopolymer und dessen verwendung
DE59609660D1 (de) Gleitlagerwerkstoff und dessen verwendung
DE69911378D1 (de) Fluorierte ionomere und verwendung davon
DE69915066D1 (de) Biozide zusammensetzung und deren verwendung
ATE430734T1 (de) Isochinoline und deren herstellung
DE59802439D1 (de) Spiroverbindungen und deren verwendung
ATE238342T1 (de) Neue thrombin-inhibitoren, deren herstellung und verwendung
DE59711118D1 (de) Spickeln, Zunehmen und Mindern
DE69817432D1 (de) Cycloolefinpolymere und deren Verwendung
ATE225342T1 (de) Benzofuran-derivate und deren verwendung
DE59709806D1 (de) Cycloolefincopolymere, ihre verwendung und daraus hergestellte formkörper
ATE186447T1 (de) Zusammensetzung und verwendung
DE69713512D1 (de) Substituierte phtalocyanine und deren verwendung
DE59705120D1 (de) Häckselmaschine und Fördervorrichtung
DE69729449D1 (de) Rekombinante alpha-2,3-sialyltransferasen und deren verwendung
ATE353367T1 (de) Group b streptococcus proteine und deren verwendung
DE69907802D1 (de) Thermisch wirkende Pflaster und seiner Verwendung
DE69835007D1 (de) Entkoffeinierte mate-extrakte und deren verwendung
DE69916694D1 (de) 2-Hydroxy-5-methyl-hexan-3-on und 3-hydroxy-5-methyl-hexan-2-on
DE59810405D1 (de) Spiroverbindungen und deren verwendung

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1141308

Country of ref document: EP

REN Ceased due to non-payment of the annual fee