ATE353455T1 - Verfahren zur sequenzanalyse - Google Patents

Verfahren zur sequenzanalyse

Info

Publication number
ATE353455T1
ATE353455T1 AT01949637T AT01949637T ATE353455T1 AT E353455 T1 ATE353455 T1 AT E353455T1 AT 01949637 T AT01949637 T AT 01949637T AT 01949637 T AT01949637 T AT 01949637T AT E353455 T1 ATE353455 T1 AT E353455T1
Authority
AT
Austria
Prior art keywords
base
sequence
unknown
reporter
bases
Prior art date
Application number
AT01949637T
Other languages
English (en)
Inventor
Raj Amersham Odedra
Original Assignee
Ge Healthcare Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Uk Ltd filed Critical Ge Healthcare Uk Ltd
Application granted granted Critical
Publication of ATE353455T1 publication Critical patent/ATE353455T1/de

Links

Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/20Sequence assembly
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids

Landscapes

  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Evolutionary Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT01949637T 2000-07-05 2001-07-02 Verfahren zur sequenzanalyse ATE353455T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0016472.3A GB0016472D0 (en) 2000-07-05 2000-07-05 Sequencing method and apparatus

Publications (1)

Publication Number Publication Date
ATE353455T1 true ATE353455T1 (de) 2007-02-15

Family

ID=9895041

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01949637T ATE353455T1 (de) 2000-07-05 2001-07-02 Verfahren zur sequenzanalyse

Country Status (11)

Country Link
US (1) US7133782B2 (de)
EP (1) EP1297484B1 (de)
JP (1) JP2004501669A (de)
AT (1) ATE353455T1 (de)
AU (1) AU2001270760A1 (de)
CA (1) CA2412973A1 (de)
DE (1) DE60126491T2 (de)
ES (1) ES2281426T3 (de)
GB (1) GB0016472D0 (de)
IL (1) IL153472A0 (de)
WO (1) WO2002003305A2 (de)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6780591B2 (en) 1998-05-01 2004-08-24 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US7875440B2 (en) 1998-05-01 2011-01-25 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US7056661B2 (en) 1999-05-19 2006-06-06 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
US7501245B2 (en) 1999-06-28 2009-03-10 Helicos Biosciences Corp. Methods and apparatuses for analyzing polynucleotide sequences
US6818395B1 (en) 1999-06-28 2004-11-16 California Institute Of Technology Methods and apparatus for analyzing polynucleotide sequences
AU2002227156A1 (en) 2000-12-01 2002-06-11 Visigen Biotechnologies, Inc. Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
JP2004523243A (ja) 2001-03-12 2004-08-05 カリフォルニア インスティチュート オブ テクノロジー 非同期性塩基伸長によってポリヌクレオチド配列を分析するための方法および装置
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
WO2005080605A2 (en) 2004-02-19 2005-09-01 Helicos Biosciences Corporation Methods and kits for analyzing polynucleotide sequences
US7635562B2 (en) 2004-05-25 2009-12-22 Helicos Biosciences Corporation Methods and devices for nucleic acid sequence determination
US7476734B2 (en) 2005-12-06 2009-01-13 Helicos Biosciences Corporation Nucleotide analogs
CA2579150C (en) 2004-09-17 2014-11-25 Pacific Biosciences Of California, Inc. Apparatus and method for analysis of molecules
US7170050B2 (en) 2004-09-17 2007-01-30 Pacific Biosciences Of California, Inc. Apparatus and methods for optical analysis of molecules
US7220549B2 (en) 2004-12-30 2007-05-22 Helicos Biosciences Corporation Stabilizing a nucleic acid for nucleic acid sequencing
US7482120B2 (en) 2005-01-28 2009-01-27 Helicos Biosciences Corporation Methods and compositions for improving fidelity in a nucleic acid synthesis reaction
US7805081B2 (en) * 2005-08-11 2010-09-28 Pacific Biosciences Of California, Inc. Methods and systems for monitoring multiple optical signals from a single source
US7666593B2 (en) 2005-08-26 2010-02-23 Helicos Biosciences Corporation Single molecule sequencing of captured nucleic acids
US7405281B2 (en) * 2005-09-29 2008-07-29 Pacific Biosciences Of California, Inc. Fluorescent nucleotide analogs and uses therefor
US7763423B2 (en) * 2005-09-30 2010-07-27 Pacific Biosciences Of California, Inc. Substrates having low density reactive groups for monitoring enzyme activity
US7998717B2 (en) 2005-12-02 2011-08-16 Pacific Biosciences Of California, Inc. Mitigation of photodamage in analytical reactions
US7715001B2 (en) 2006-02-13 2010-05-11 Pacific Biosciences Of California, Inc. Methods and systems for simultaneous real-time monitoring of optical signals from multiple sources
US7692783B2 (en) * 2006-02-13 2010-04-06 Pacific Biosciences Of California Methods and systems for simultaneous real-time monitoring of optical signals from multiple sources
US7995202B2 (en) * 2006-02-13 2011-08-09 Pacific Biosciences Of California, Inc. Methods and systems for simultaneous real-time monitoring of optical signals from multiple sources
US8301394B2 (en) * 2006-02-16 2012-10-30 454 Life Sciences Corporation System and method for correcting primer extension errors in nucleic acid sequence data
US8364417B2 (en) 2007-02-15 2013-01-29 454 Life Sciences Corporation System and method to correct out of phase errors in DNA sequencing data by use of a recursive algorithm
US7397546B2 (en) 2006-03-08 2008-07-08 Helicos Biosciences Corporation Systems and methods for reducing detected intensity non-uniformity in a laser beam
US20080050747A1 (en) * 2006-03-30 2008-02-28 Pacific Biosciences Of California, Inc. Articles having localized molecules disposed thereon and methods of producing and using same
US8975216B2 (en) 2006-03-30 2015-03-10 Pacific Biosciences Of California Articles having localized molecules disposed thereon and methods of producing same
US7563574B2 (en) 2006-03-31 2009-07-21 Pacific Biosciences Of California, Inc. Methods, systems and compositions for monitoring enzyme activity and applications thereof
US8053191B2 (en) 2006-08-31 2011-11-08 Westend Asset Clearinghouse Company, Llc Iterative nucleic acid assembly using activation of vector-encoded traits
WO2008028160A2 (en) * 2006-09-01 2008-03-06 Pacific Biosciences Of California, Inc. Substrates, systems and methods for analyzing materials
US8207509B2 (en) 2006-09-01 2012-06-26 Pacific Biosciences Of California, Inc. Substrates, systems and methods for analyzing materials
US20080080059A1 (en) * 2006-09-28 2008-04-03 Pacific Biosciences Of California, Inc. Modular optical components and systems incorporating same
US20100167413A1 (en) * 2007-05-10 2010-07-01 Paul Lundquist Methods and systems for analyzing fluorescent materials with reduced autofluorescence
US20080277595A1 (en) * 2007-05-10 2008-11-13 Pacific Biosciences Of California, Inc. Highly multiplexed confocal detection systems and methods of using same
US7767441B2 (en) * 2007-10-25 2010-08-03 Industrial Technology Research Institute Bioassay system including optical detection apparatuses, and method for detecting biomolecules
US7811810B2 (en) 2007-10-25 2010-10-12 Industrial Technology Research Institute Bioassay system including optical detection apparatuses, and method for detecting biomolecules
EP4230747A3 (de) 2008-03-28 2023-11-15 Pacific Biosciences Of California, Inc. Zusammensetzungen und verfahren zur nukleinsäuresequenzierung
WO2010025310A2 (en) 2008-08-27 2010-03-04 Westend Asset Clearinghouse Company, Llc Methods and devices for high fidelity polynucleotide synthesis
EP2331934B1 (de) 2008-09-16 2020-01-01 Pacific Biosciences of California, Inc. Analysegerät mit Nullmoden-Wellenleiter Substrat
US8501406B1 (en) 2009-07-14 2013-08-06 Pacific Biosciences Of California, Inc. Selectively functionalized arrays
US10207240B2 (en) 2009-11-03 2019-02-19 Gen9, Inc. Methods and microfluidic devices for the manipulation of droplets in high fidelity polynucleotide assembly
WO2011066185A1 (en) 2009-11-25 2011-06-03 Gen9, Inc. Microfluidic devices and methods for gene synthesis
WO2011085075A2 (en) 2010-01-07 2011-07-14 Gen9, Inc. Assembly of high fidelity polynucleotides
US9646134B2 (en) 2010-05-25 2017-05-09 The Regents Of The University Of California Bambam: parallel comparative analysis of high-throughput sequencing data
KR102042253B1 (ko) 2010-05-25 2019-11-07 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 Bambam:고처리율 서열분석 데이터의 병렬 비교 분석
AU2011226792A1 (en) 2010-06-11 2012-01-12 Life Technologies Corporation Alternative nucleotide flows in sequencing-by-synthesis methods
WO2012021733A2 (en) 2010-08-12 2012-02-16 Pacific Biosciences Of California, Inc. Photodamage mitigation compounds and systems
US10273540B2 (en) 2010-10-27 2019-04-30 Life Technologies Corporation Methods and apparatuses for estimating parameters in a predictive model for use in sequencing-by-synthesis
US8666678B2 (en) 2010-10-27 2014-03-04 Life Technologies Corporation Predictive model for use in sequencing-by-synthesis
CN103502448B (zh) 2010-11-12 2017-03-29 Gen9股份有限公司 核酸合成的方法和设备
WO2012064975A1 (en) 2010-11-12 2012-05-18 Gen9, Inc. Protein arrays and methods of using and making the same
EP2659408B1 (de) 2010-12-29 2019-03-27 Life Technologies Corporation Zeitverzerrtes hintergrundsignal für sequenzierung-mit-synthese-operationen
US10241075B2 (en) 2010-12-30 2019-03-26 Life Technologies Corporation Methods, systems, and computer readable media for nucleic acid sequencing
US20130060482A1 (en) 2010-12-30 2013-03-07 Life Technologies Corporation Methods, systems, and computer readable media for making base calls in nucleic acid sequencing
EP3582224B1 (de) 2010-12-30 2026-04-29 Life Technologies Corporation Modelle zur analyse von daten aus sequenzierung-mit-synthese-operationen
CN103764845B (zh) 2011-04-08 2016-02-17 生命科技股份有限公司 用于合成测序中的相保护试剂流排序
US9752176B2 (en) 2011-06-15 2017-09-05 Ginkgo Bioworks, Inc. Methods for preparative in vitro cloning
LT2944693T (lt) 2011-08-26 2019-08-26 Gen9, Inc. Kompozicijos ir būdai, skirti nukleorūgščių didelio tikslumo sąrankai
US20150087537A1 (en) 2011-08-31 2015-03-26 Life Technologies Corporation Methods, Systems, Computer Readable Media, and Kits for Sample Identification
US10704164B2 (en) 2011-08-31 2020-07-07 Life Technologies Corporation Methods, systems, computer readable media, and kits for sample identification
KR101295784B1 (ko) * 2011-10-31 2013-08-12 삼성에스디에스 주식회사 목표 유전체 서열 내의 신규서열 생성 장치 및 방법
US9150853B2 (en) 2012-03-21 2015-10-06 Gen9, Inc. Methods for screening proteins using DNA encoded chemical libraries as templates for enzyme catalysis
CA2871505C (en) 2012-04-24 2021-10-12 Gen9, Inc. Methods for sorting nucleic acids and multiplexed preparative in vitro cloning
US9646132B2 (en) 2012-05-11 2017-05-09 Life Technologies Corporation Models for analyzing data from sequencing-by-synthesis operations
IL236303B (en) 2012-06-25 2022-07-01 Gen9 Inc Methods for high-throughput nucleic acid assembly and sequencing
US10329608B2 (en) 2012-10-10 2019-06-25 Life Technologies Corporation Methods, systems, and computer readable media for repeat sequencing
US20140296080A1 (en) 2013-03-14 2014-10-02 Life Technologies Corporation Methods, Systems, and Computer Readable Media for Evaluating Variant Likelihood
US9926597B2 (en) 2013-07-26 2018-03-27 Life Technologies Corporation Control nucleic acid sequences for use in sequencing-by-synthesis and methods for designing the same
CN105683980B (zh) 2013-10-04 2018-08-24 生命科技股份有限公司 在使用终止化学物质的测序中建立分阶段效应模型的方法和系统
WO2016060974A1 (en) 2014-10-13 2016-04-21 Life Technologies Corporation Methods, systems, and computer-readable media for accelerated base calling
EP4220645A3 (de) 2015-05-14 2023-11-08 Life Technologies Corporation Barcodesequenzen sowie zugehörige systeme und verfahren
US10619205B2 (en) 2016-05-06 2020-04-14 Life Technologies Corporation Combinatorial barcode sequences, and related systems and methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302509A (en) * 1989-08-14 1994-04-12 Beckman Instruments, Inc. Method for sequencing polynucleotides
WO1991006678A1 (en) * 1989-10-26 1991-05-16 Sri International Dna sequencing
WO1993005183A1 (en) 1991-09-09 1993-03-18 Baylor College Of Medicine Method and device for rapid dna or rna sequencing determination by a base addition sequencing scheme
GB9208733D0 (en) 1992-04-22 1992-06-10 Medical Res Council Dna sequencing method
US5552278A (en) * 1994-04-04 1996-09-03 Spectragen, Inc. DNA sequencing by stepwise ligation and cleavage

Also Published As

Publication number Publication date
WO2002003305A2 (en) 2002-01-10
US20030186276A1 (en) 2003-10-02
IL153472A0 (en) 2003-07-06
CA2412973A1 (en) 2002-01-10
AU2001270760A1 (en) 2002-01-14
WO2002003305A3 (en) 2002-08-01
GB0016472D0 (en) 2000-08-23
US7133782B2 (en) 2006-11-07
DE60126491T2 (de) 2007-11-15
JP2004501669A (ja) 2004-01-22
EP1297484B1 (de) 2007-02-07
DE60126491D1 (de) 2007-03-22
ES2281426T3 (es) 2007-10-01
EP1297484A2 (de) 2003-04-02

Similar Documents

Publication Publication Date Title
ATE353455T1 (de) Verfahren zur sequenzanalyse
ATE244771T1 (de) Verfahren zur erkennung von nukleinsäuremethylierungen durch aflp
DE50113548D1 (de) Verfahren zum Nachweis von Influenza A/B-Viren in Speichel
ATE423221T1 (de) Verwendung von mass-matched nukleotide in der analyse von oligonukleotidmischungen sowie in der hoch-multiplexen nukleinsäuresequenzierung
DE60041355D1 (de) Verfahren zur detektion von erkrankungen
DE60325482D1 (de) Verfahren zur charakterisierung von biomolekülen mittels resultat-gesteuerter strategie
DE69842134D1 (de) Elektronische verfahren und vorrichtung zum nachweis von analyten
HUP9901321A2 (hu) Eljárások és készítmények nukleinsav-molekulák szekvenciájának maghatározására
ATE212674T1 (de) Verfahren und analytisches system zur genauen schnellen und einfachen ausführung von fibrinogen-assays
DE69521811D1 (de) Verfahren zur vermeidung überflüssiger identifizierungen (verursacht durch antefakten in bildern von bakterienkolonien)
DK0925373T3 (da) Fremgangsmåde til påvisning af nukleinsyrer ved fastlæggelse af massen
DE3751169D1 (de) Zusammensetzungen und Verfahren zur Synthese und Analyse von Enkephalinase.
ATE115728T1 (de) Verfahren zur verminderung von störungen in einer fluoreszenzbestimmung.
EA200200435A1 (ru) Анализ лептина
DE59812184D1 (de) Verfahren zur identifikation von nucleinsäuren durch elektrospray massenspektrometrie
ATE103990T1 (de) Verfahren zur diagnose der periodontalen krankheit mittels nachweis von alaninaminotransferase.
DE69941690D1 (de) Methoden, testsätze und kompositionen zur detektion und quantifizierung von zielsequenzen
DE60127404D1 (de) Verfahren zur messung von durch transferrin nicht-gebundenem eisen
ATE330037T1 (de) Verfahren zur altersbestimmung von individuen
DE50100332D1 (de) Vorrichtung und verfahren zum bestimmen eines codierungs-blockrasters eines decodierten signals
DE3671811D1 (de) Verfahren zur herstellung von halbleiteranordnungen mittels gasaetzen.
ATE347913T1 (de) Verfahren zur identifizierung von wächter- lymphknoten
DE60139333D1 (de) Verfahren zum nachweis von norwalk-ähnlichem virus (gii)
DE69632826D1 (de) Nukleinsaeure erkennung von hepatitis gb virus
DE60108074D1 (de) Verfahren zur identifizierung von igg-produzierenden zellen

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties