ATE354566T1 - Aromatische sulfone und deren medizinische verwendung - Google Patents

Aromatische sulfone und deren medizinische verwendung

Info

Publication number: ATE354566T1
Authority: AT; Austria
Prior art keywords: medical use; aromatic sulfones; sulfones; aromatic; medical
Prior art date: 2002-05-29

Application number

AT03755153T

Other languages

English (en)

Inventor

Andrew Derrick Gribble

Ian Thomson Forbes

Andrew Lightfoot

Andrew H Payne

Graham Walker

Vincenzo Garzya

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-05-29

Filing date

2003-05-28

Publication date

2007-03-15

2002-05-29 Priority claimed from GB0212401A external-priority patent/GB0212401D0/en

2002-12-23 Priority claimed from GB0230053A external-priority patent/GB0230053D0/en

2003-05-28 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2007-03-15 Application granted granted Critical

2007-03-15 Publication of ATE354566T1 publication Critical patent/ATE354566T1/de

Links

150000003457 sulfones Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Addiction (AREA)
Diabetes (AREA)
Psychology (AREA)
Obesity (AREA)
Hematology (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Cardiology (AREA)
Otolaryngology (AREA)
Heart & Thoracic Surgery (AREA)
Child & Adolescent Psychology (AREA)
Gynecology & Obstetrics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)
Hydrogenated Pyridines (AREA)

AT03755153T 2002-05-29 2003-05-28 Aromatische sulfone und deren medizinische verwendung ATE354566T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB0212401A GB0212401D0 (en)	2002-05-29	2002-05-29	Compounds
GB0230053A GB0230053D0 (en)	2002-12-23	2002-12-23	Compounds

Publications (1)

Publication Number	Publication Date
ATE354566T1 true ATE354566T1 (de)	2007-03-15

Family

ID=29585827

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03755153T ATE354566T1 (de)	2002-05-29	2003-05-28	Aromatische sulfone und deren medizinische verwendung

Country Status (25)

Country	Link
US (2)	US7504392B2 (de)
EP (1)	EP1511727B1 (de)
JP (1)	JP4268126B2 (de)
KR (1)	KR20050013196A (de)
AR (1)	AR040126A1 (de)
AT (1)	ATE354566T1 (de)
AU (1)	AU2003232846B9 (de)
BR (1)	BR0311315A (de)
CA (1)	CA2486962A1 (de)
CY (1)	CY1107053T1 (de)
DE (1)	DE60311986T2 (de)
DK (1)	DK1511727T3 (de)
ES (1)	ES2279965T3 (de)
IL (1)	IL165330A0 (de)
IS (1)	IS2482B (de)
MX (1)	MXPA04011945A (de)
MY (1)	MY133587A (de)
NO (1)	NO330118B1 (de)
NZ (1)	NZ536694A (de)
PL (1)	PL374081A1 (de)
PT (1)	PT1511727E (de)
RU (1)	RU2327690C2 (de)
SI (1)	SI1511727T1 (de)
TW (1)	TWI281914B (de)
WO (1)	WO2003099786A2 (de)

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TWI281914B (en)	2002-05-29	2007-06-01	Glaxo Group Ltd	Compounds
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GB0319235D0 (en) *	2003-08-15	2003-09-17	Glaxo Group Ltd	Novel compounds
GB0327740D0 (en) *	2003-11-28	2003-12-31	Glaxo Group Ltd	Novel compounds
GB0327738D0 (en) *	2003-11-28	2003-12-31	Glaxo Group Ltd	Novel compound
GB0327741D0 (en) *	2003-11-28	2003-12-31	Glaxo Group Ltd	Novel compounds
GB0327737D0 (en) *	2003-11-28	2003-12-31	Glaxo Group Ltd	Novel compounds
GB0505437D0 (en) *	2005-03-17	2005-04-20	Merck Sharp & Dohme	Therapeutic agents
GB0505725D0 (en) *	2005-03-19	2005-04-27	Merck Sharp & Dohme	Therapeutic agents
WO2006105527A2 (en) *	2005-03-31	2006-10-05	Amylin Pharmaceuticals, Inc.	Amylin and amylin agonists for treating psychiatric diseases and disorders
GB0510599D0 (en) *	2005-05-24	2005-06-29	Glaxo Group Ltd	Novel compounds
GB0603087D0 (en) *	2006-02-15	2006-03-29	Glaxo Group Ltd	Novel use
WO2007149728A2 (en) *	2006-06-20	2007-12-27	Alcon Research, Ltd.	Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma
RU2450004C2 (ru) *	2006-08-04	2012-05-10	Мерц Фарма Гмбх Унд Ко. Кгаа	Замещенные пиразолопиримидины, способ их получения и их применение в качестве лекарственного средства
ES2545275T3 (es) *	2008-11-06	2015-09-09	Ventirx Pharmaceuticals, Inc.	Métodos de síntesis de derivados de benzazepinas
US20180228811A1 (en) *	2014-12-12	2018-08-16	The Schepens Eye Research Institute, Inc.	Gdnf induction for the treatment of retinal disorders
US11124497B1 (en)	2020-04-17	2021-09-21	Pardes Biosciences, Inc.	Inhibitors of cysteine proteases and methods of use thereof
US11174231B1 (en)	2020-06-09	2021-11-16	Pardes Biosciences, Inc.	Inhibitors of cysteine proteases and methods of use thereof
US12577240B2 (en)	2020-07-11	2026-03-17	Pfizer Inc.	Antiviral heteroaryl ketone derivatives
US11351149B2 (en)	2020-09-03	2022-06-07	Pfizer Inc.	Nitrile-containing antiviral compounds

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JP2003500386A (ja)	1999-05-24	2003-01-07	シーオーアールセラピューティクスインコーポレイテッド	Ｘａ因子阻害剤
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CA2408486A1 (en)	2000-05-11	2001-11-15	Bristol-Myers Squibb Company	Tetrahydroisoquinoline analogs useful as growth hormone secretagogues
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CA2390535C (en)	2000-09-14	2008-12-02	Edmund Gene Butts	Curling garment brush retainer
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US7429579B2 (en) *	2000-11-14	2008-09-30	Smithkline Beecham, Plc	Tetrahydrobenzazepine derivatives useful as modulators of dopamine D3 receptors (antipsychotic agents)
JP2004515494A (ja)	2000-12-07	2004-05-27	アストラゼネカ・アクチエボラーグ	治療剤
GB0111186D0 (en)	2001-05-08	2001-06-27	Smithkline Beecham Plc	Novel compounds
WO2003062205A1 (en)	2001-12-21	2003-07-31	Smithkline Beecham P.L.C.	7-sulfonyl-3-benzazepine derivatives as modulators of the dopamine receptor and their use for the treatment of cns disorders
US20050222124A1 (en)	2002-02-13	2005-10-06	Bromidge Steven M	Benzenesulfonamide derivatives as antipsychotic agents
US20050090485A1 (en)	2002-02-13	2005-04-28	Bromidge Steven M.	7-Arylsulfonamido-2,3,4,5-tetrahydro-1h-benzo'diazepine derivatives with 5ht6 receptor affinity for the reatment of cns disorders
EP1495004A2 (de)	2002-02-13	2005-01-12	Glaxo Group Limited	Benzensulfonamidderivate und deren verwendung als dopamin d2 und d3 rezeptor liganden
GB0210762D0 (en)	2002-05-10	2002-06-19	Glaxo Group Ltd	Compounds
TWI281914B (en)	2002-05-29	2007-06-01	Glaxo Group Ltd	Compounds
GB0212399D0 (en)	2002-05-29	2002-07-10	Glaxo Group Ltd	Compounds

2003
- 2003-05-27 TW TW092114200A patent/TWI281914B/zh not_active IP Right Cessation
- 2003-05-27 AR ARP030101854A patent/AR040126A1/es unknown
- 2003-05-27 MY MYPI20031957A patent/MY133587A/en unknown
- 2003-05-28 MX MXPA04011945A patent/MXPA04011945A/es active IP Right Grant
- 2003-05-28 US US10/515,998 patent/US7504392B2/en not_active Expired - Fee Related
- 2003-05-28 NZ NZ536694A patent/NZ536694A/en not_active IP Right Cessation
- 2003-05-28 AT AT03755153T patent/ATE354566T1/de active
- 2003-05-28 PT PT03755153T patent/PT1511727E/pt unknown
- 2003-05-28 SI SI200330757T patent/SI1511727T1/sl unknown
- 2003-05-28 EP EP03755153A patent/EP1511727B1/de not_active Expired - Lifetime
- 2003-05-28 KR KR10-2004-7019172A patent/KR20050013196A/ko not_active Abandoned
- 2003-05-28 DE DE60311986T patent/DE60311986T2/de not_active Expired - Lifetime
- 2003-05-28 DK DK03755153T patent/DK1511727T3/da active
- 2003-05-28 CA CA002486962A patent/CA2486962A1/en not_active Abandoned
- 2003-05-28 RU RU2004138588/04A patent/RU2327690C2/ru not_active IP Right Cessation
- 2003-05-28 IL IL16533003A patent/IL165330A0/xx not_active IP Right Cessation
- 2003-05-28 PL PL03374081A patent/PL374081A1/xx not_active Application Discontinuation
- 2003-05-28 ES ES03755153T patent/ES2279965T3/es not_active Expired - Lifetime
- 2003-05-28 JP JP2004507444A patent/JP4268126B2/ja not_active Expired - Fee Related
- 2003-05-28 BR BR0311315-9A patent/BR0311315A/pt not_active Application Discontinuation
- 2003-05-28 WO PCT/EP2003/005727 patent/WO2003099786A2/en not_active Ceased
- 2003-05-28 AU AU2003232846A patent/AU2003232846B9/en not_active Ceased
2004
- 2004-12-01 IS IS7577A patent/IS2482B/is unknown
- 2004-12-27 NO NO20045659A patent/NO330118B1/no not_active IP Right Cessation
2007
- 2007-04-30 CY CY20071100580T patent/CY1107053T1/el unknown
2008
- 2008-06-24 US US12/144,917 patent/US20080269197A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CY1107053T1 (el)	2012-10-24
PL374081A1 (en)	2005-09-19
KR20050013196A (ko)	2005-02-03
EP1511727A2 (de)	2005-03-09
HK1075050A1 (en)	2005-12-02
IL165330A0 (en)	2006-01-15
TW200406381A (en)	2004-05-01
JP4268126B2 (ja)	2009-05-27
ES2279965T3 (es)	2007-09-01
US7504392B2 (en)	2009-03-17
TWI281914B (en)	2007-06-01
WO2003099786A2 (en)	2003-12-04
SI1511727T1 (sl)	2007-06-30
BR0311315A (pt)	2005-03-01
EP1511727B1 (de)	2007-02-21
US20080269197A1 (en)	2008-10-30
NO20045659L (no)	2004-12-27
RU2004138588A (ru)	2005-06-27
WO2003099786A3 (en)	2004-09-02
AU2003232846B9 (en)	2007-04-19
JP2005531579A (ja)	2005-10-20
AU2003232846B2 (en)	2007-02-22
US20050261279A1 (en)	2005-11-24
RU2327690C2 (ru)	2008-06-27
MXPA04011945A (es)	2005-03-31
CA2486962A1 (en)	2003-12-04
PT1511727E (pt)	2007-05-31
AR040126A1 (es)	2005-03-16
MY133587A (en)	2007-11-30
NZ536694A (en)	2006-11-30
DE60311986D1 (de)	2007-04-05
IS2482B (is)	2008-12-15
DE60311986T2 (de)	2007-10-31
IS7577A (is)	2004-12-01
DK1511727T3 (da)	2007-06-11
AU2003232846A1 (en)	2003-12-12
NO330118B1 (no)	2011-02-21

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2007-08-15

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