ATE354677T1 - Detektionsverfahren für papillomavirus mrna - Google Patents

Detektionsverfahren für papillomavirus mrna

Info

Publication number
ATE354677T1
ATE354677T1 AT03700338T AT03700338T ATE354677T1 AT E354677 T1 ATE354677 T1 AT E354677T1 AT 03700338 T AT03700338 T AT 03700338T AT 03700338 T AT03700338 T AT 03700338T AT E354677 T1 ATE354677 T1 AT E354677T1
Authority
AT
Austria
Prior art keywords
mrna
detection method
risk
expression
cervical carcinoma
Prior art date
Application number
AT03700338T
Other languages
English (en)
Inventor
Frank Karlsen
Original Assignee
Norchip As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26246916&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE354677(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0200239A external-priority patent/GB0200239D0/en
Priority claimed from GB0214124A external-priority patent/GB0214124D0/en
Application filed by Norchip As filed Critical Norchip As
Application granted granted Critical
Publication of ATE354677T1 publication Critical patent/ATE354677T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/708Specific hybridization probes for papilloma
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT03700338T 2002-01-07 2003-01-07 Detektionsverfahren für papillomavirus mrna ATE354677T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0200239A GB0200239D0 (en) 2002-01-07 2002-01-07 Method for detecting human papillomavirus mRNA
GB0214124A GB0214124D0 (en) 2002-06-19 2002-06-19 Method for detecting human papillomavirus mRNA

Publications (1)

Publication Number Publication Date
ATE354677T1 true ATE354677T1 (de) 2007-03-15

Family

ID=26246916

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03700338T ATE354677T1 (de) 2002-01-07 2003-01-07 Detektionsverfahren für papillomavirus mrna

Country Status (20)

Country Link
US (4) US7553623B2 (de)
EP (5) EP2267155B2 (de)
JP (2) JP4558322B2 (de)
CN (1) CN100422342C (de)
AT (1) ATE354677T1 (de)
AU (2) AU2003201639C1 (de)
BR (1) BR0306723A (de)
CA (1) CA2472026A1 (de)
CY (1) CY1106621T1 (de)
DE (1) DE60311961T2 (de)
DK (2) DK2913407T3 (de)
EA (1) EA006975B1 (de)
ES (2) ES2654909T3 (de)
IL (2) IL162722A0 (de)
MX (1) MXPA04006440A (de)
NO (1) NO20042769L (de)
NZ (1) NZ533703A (de)
PT (1) PT1463839E (de)
SI (1) SI1463839T1 (de)
WO (1) WO2003057914A2 (de)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7601497B2 (en) 2000-06-15 2009-10-13 Qiagen Gaithersburg, Inc. Detection of nucleic acids by target-specific hybrid capture method
US7439016B1 (en) * 2000-06-15 2008-10-21 Digene Corporation Detection of nucleic acids by type-specific hybrid capture method
US20110111389A1 (en) * 2001-11-07 2011-05-12 Diagcor Bioscience Incorporation Limited Rapid genotyping analysis for human papillomavirus and the device thereof
EP2267155B2 (de) 2002-01-07 2016-09-07 Norchip A/S Detektionsverfahren für Papillomavirus mRNA
EP1369694A1 (de) * 2002-04-09 2003-12-10 MTM Laboratories AG Verfahren zur Unterscheidung zwischen Metaplasien und neoplastischen oder präneoplastischen Läsionen
US7741031B2 (en) * 2003-03-07 2010-06-22 The Public Health Research Institute Of The City Of New York Optically decodable microcarries, arrays and methods
US7361460B2 (en) * 2003-04-11 2008-04-22 Digene Corporation Approach to molecular diagnosis of human papillomavirus-related diseases
EP1510820B1 (de) * 2003-08-25 2010-03-17 MTM Laboratories AG Verfahren zum Nachweis von medizinisch relevanten Zuständen in gelösten LBC-Proben
ATE289685T1 (de) * 2003-08-25 2005-03-15 Mtm Lab Ag Verfahren zum nachweis von karzinomen in solubilisierten zervikalen körperproben
EP1664348B8 (de) * 2003-09-25 2019-06-12 Third Wave Technologies, Inc. Hpv-nachweis
WO2005033333A2 (en) 2003-10-07 2005-04-14 Dako Denmark A/S Methods and compositions for the diagnosis of cancer
WO2005062940A2 (en) 2003-12-22 2005-07-14 John Wayne Cancer Institute Method and apparatus for in vivo collection and surveillance of circulating biological components
GB0404315D0 (en) * 2004-02-26 2004-03-31 Norchip As Improved detection of human papillomavirus
ITMO20040126A1 (it) 2004-05-21 2004-08-21 Bioanalisi Ct Sud S N C Di Per Sistema per la ricerca ed identificazione di agenti patogeni
WO2006137939A2 (en) 2004-11-09 2006-12-28 Gen-Probe Incorporated Compositions and methods for detecting group a streptococci
EP1819835B1 (de) 2004-12-08 2010-08-04 Gen-Probe Incorporated Nukleinsäuredetektion aus verschiedenen typen des humanen papillomavirus
DK2500439T4 (da) 2005-06-20 2017-11-13 Advanced Cell Diagnostics Inc Kits og produkter til detektering af nukleinsyrer i individuelle celler og til identifikation af sjældne celler fra store heterogene cellepopulationer
EP1844164B1 (de) * 2005-11-15 2010-07-14 Genoid KFT Verfahren zum nachweis von pathogenen mittels molecular beacons
WO2007115582A1 (en) 2006-04-11 2007-10-18 Bio-Rad Pasteur Hpv detection and quantification by real-time multiplex amplification
US7833716B2 (en) * 2006-06-06 2010-11-16 Gen-Probe Incorporated Tagged oligonucleotides and their use in nucleic acid amplification methods
US20100285443A1 (en) * 2006-12-15 2010-11-11 Oncomethylome Sciences Sa Diagnostic Methods for Diseases Caused by a HPV Infection Comprising Determining the Methylation Status of the HPV Genome
EP3095873B1 (de) 2006-12-21 2018-04-18 Gen-Probe Incorporated Verfahren und zusammensetzungen zur amplifizierung von nukleinsäuren
US7838215B2 (en) * 2007-09-25 2010-11-23 Canvir, Inc. Advanced cervical cell screening methods
US9435001B2 (en) 2007-11-01 2016-09-06 Self-Screen B.V. Detection method for cervical HPVS
JP5299986B2 (ja) * 2007-11-01 2013-09-25 国立大学法人山口大学 核酸の定量方法
CA2726396C (en) * 2008-04-17 2019-03-19 Qiagen Gaithersburg, Inc. Compositions, methods, and kits using synthetic probes for determining the presence of a target nucleic acid
US9090948B2 (en) * 2008-09-30 2015-07-28 Abbott Molecular Inc. Primers and probes for detecting human papillomavirus and human beta globin sequences in test samples
TWI419974B (zh) 2008-10-27 2013-12-21 Qiagen Gaithersburg Inc 於自動平台上之快速結果雜交捕捉法
EP2184368A1 (de) 2008-11-07 2010-05-12 DKFZ Deutsches Krebsforschungszentrum Diagnosetranskript- und Spleißmuster von HPV16 bei verschiedenen Halsverletzungen
WO2010127228A1 (en) * 2009-05-01 2010-11-04 Qiagen Gaithersburg, Inc. A non-target amplification method for detection of rna splice-forms in a sample
JP5826752B2 (ja) * 2009-09-14 2015-12-02 キアジェン ゲイサーズバーグ インコーポレイテッド 細胞学用培地に固定された組織サンプルから核酸またはタンパク質を回収するための組成物および方法
AU2011203450B2 (en) * 2010-01-04 2016-01-07 Qiagen Gaithersburg, Inc. Methods, compositions, and kits for recovery of nucleic acids or proteins from fixed tissue samples
JP2013517803A (ja) 2010-01-29 2013-05-20 キアジェン ゲイサーズバーグ インコーポレイテッド サンプル中のhpvの存在を決定および確認する方法
CA2787924A1 (en) * 2010-01-29 2011-08-04 Qiagen Gaithersburg, Inc. Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids
US20110275698A1 (en) * 2010-05-10 2011-11-10 Norchip A/S "test and treat" strategy for treating transforming hpv infection
EP2572001A2 (de) 2010-05-19 2013-03-27 QIAGEN Gaithersburg, Inc. Verfahren und zusammensetzungen für sequenzspezifische reinigung und multiplex-analyse von nukleinsäuren
JP6153866B2 (ja) 2010-05-25 2017-06-28 キアゲン ガイサーズバーグ アイエヌシー. 迅速なハイブリッド捕捉アッセイ、及び関連する戦略的に切断されたプローブ
US8658361B2 (en) 2010-10-21 2014-02-25 Advanced Cell Diagnostics, Inc. Ultra sensitive method for in situ detection of nucleic acids
BR112013017489B1 (pt) * 2011-01-07 2021-06-08 Qiagen Gaithersburg, Inc "métodos para genotipagem de hpv de alto risco e para distinguir entre infecções por hpv 16, hpv 18 e hpv 45".
EP2668290B1 (de) * 2011-01-28 2017-05-31 Advanced Cell Diagnostics, Inc. Rnascope®-hpv-assay zur bestimmung des hpv-status in kopf- und halstumoren und zervixläsionen
WO2012116220A2 (en) 2011-02-24 2012-08-30 Qiagen Gaithersburg, Inc. Materials and methods for detection of hpv nucleic acid
US20130095474A1 (en) * 2011-10-13 2013-04-18 Joseph Mamone Design of stem-loop probes and utilization in snp genotyping
ES2730711T3 (es) 2011-11-03 2019-11-12 Qiagen Gaithersburg Inc Materiales y métodos para inmovilizar, aislar y concentrar células usando superficies carboxiladas
CN102864224A (zh) * 2012-09-11 2013-01-09 南京大学 一种血清microRNAs试剂盒及其应用
GB201310933D0 (en) 2013-06-19 2013-07-31 Norchip As A method of cervical screening
CA2932859A1 (en) * 2013-12-05 2015-06-11 Optipharm. Co., Ltd. Improved cervical cancer diagnosing method and diagnostic kit for same
WO2016005789A1 (en) * 2014-07-07 2016-01-14 Institut Pasteur Broad range gene and genotype papillomavirus transcriptome as a biomarker of papillomavirus- associated cancer stages
CN106048014B (zh) * 2016-06-07 2019-12-10 博奥生物集团有限公司 一种用于实时检测nasba产物的高特异探针
US20190112673A1 (en) * 2017-05-10 2019-04-18 Genomic Vision Association between integration of high-risk hpv genomes detected by molecular combing and the severity and/or clinical outcome of cervical lesions
JP6831772B2 (ja) 2017-12-22 2021-02-17 株式会社Subaru 画像投影装置
CN114214343A (zh) * 2021-11-15 2022-03-22 上海市东方医院(同济大学附属东方医院) 一组高危型HPV整合所致的宫颈癌中特异表达的mRNA序列

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE76429T1 (de) 1986-03-21 1992-06-15 Pasteur Institut Bestimmte, von einem papillomavirus-genom abgeleitete dns-sequenzen, deren anwendungen fuer in vitro-diagnostische zwecke und die herstellung von antigenzusammensetzungen.
EP0357611B1 (de) * 1987-02-26 1995-04-26 The University Of Sydney Verfahren zum nachweis des karzinogenen menschlichen papillomavirus
US5182377A (en) 1988-09-09 1993-01-26 Hoffmann-La Roche Inc. Probes for detection of human papillomavirus
US5639871A (en) * 1988-09-09 1997-06-17 Roche Molecular Systems, Inc. Detection of human papillomavirus by the polymerase chain reaction
DE3838269A1 (de) * 1988-11-11 1990-05-17 Behringwerke Ag Nachweis humaner papillomavirus dna und ihrer expression in zervix-abstrichen
NL8900725A (nl) 1989-03-23 1990-10-16 Az Univ Amsterdam Werkwijze en combinatie van middelen voor het isoleren van nucleinezuur.
US5234809A (en) 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
JP2791685B2 (ja) 1989-06-08 1998-08-27 寳酒造株式会社 パピローマウイルスの検出方法
US5580970A (en) * 1989-12-01 1996-12-03 Amoco Corporation Detection of HPV transcripts
DE69033850T2 (de) * 1989-12-01 2002-06-06 Vysis, Inc. Nukleinsäuresonden zum Nachweis von HPV-Transkripts
NL9000134A (nl) 1990-01-19 1991-08-16 Stichting Res Fonds Pathologie Primers en werkwijze voor het detecteren van humaan papilloma virus genotypen m.b.v. pcr.
US6582908B2 (en) * 1990-12-06 2003-06-24 Affymetrix, Inc. Oligonucleotides
US5474796A (en) 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
US5506105A (en) * 1991-12-10 1996-04-09 Dade International Inc. In situ assay of amplified intracellular mRNA targets
WO1994026934A2 (en) * 1993-05-06 1994-11-24 Baxter Diagnostics Inc. Human papillomavirus detection assay
US6174668B1 (en) * 1993-05-14 2001-01-16 Johnson & Johnson Clinical Diagnostics, Inc. Diagnostic compositions, elements, methods and test kits for amplification and detection of two or more target DNA's using primers having matched melting temperatures
DK1921169T3 (da) 1993-11-12 2012-06-04 Phri Properties Inc Hybridiseringssonder til nukleinsyredetektion, universelle stamceller, fremgangsmåder og kits
DE4431174A1 (de) * 1994-09-01 1996-03-07 Deutsches Krebsforsch Nachweisverfahren für tumorspezifische mRNA
DE19506561C1 (de) * 1995-02-24 1996-10-10 Deutsches Krebsforsch Verfahren zur Früherkennung von HPV-assoziierten Karzinomen bzw. von hochgradigen, durch HPV-verursachten Dysplasien
AU726047B2 (en) 1995-11-15 2000-10-26 Gen-Probe Incorporated Nucleic acid probes complementary to human papillomavirus nucleic acid and related methods and kits
US6027981A (en) 1997-10-27 2000-02-22 Texas Instruments - Acer Incorporated Method for forming a DRAM cell with a fork-shaped capacitor
CA2313641A1 (en) 1997-12-12 1999-06-24 Digene Corporation Universal collection medium
AU4515699A (en) 1998-06-26 2000-01-17 Akzo Nobel N.V. Tagging of rna amplicons generated by transcription-based amplification
AU2001249526A1 (en) 2000-03-28 2001-10-08 Biosearch International Pty Ltd Approaches for hpv detection and staging by targeting the e6 gene region of the viral genome
US7439016B1 (en) * 2000-06-15 2008-10-21 Digene Corporation Detection of nucleic acids by type-specific hybrid capture method
GB0018050D0 (en) * 2000-07-21 2000-09-13 Norchip As Detection of human papillomavirus mRNA
ES2276948T3 (es) * 2001-08-23 2007-07-01 MERCK & CO., INC. Ensayos pcr de hp multiplex fluorescente que usan fluoforos multiples.
GB0200258D0 (en) * 2002-01-07 2002-02-20 Norchip As Detection of human papillomavirus
EP2267155B2 (de) * 2002-01-07 2016-09-07 Norchip A/S Detektionsverfahren für Papillomavirus mRNA
GB0404315D0 (en) 2004-02-26 2004-03-31 Norchip As Improved detection of human papillomavirus

Also Published As

Publication number Publication date
CN100422342C (zh) 2008-10-01
IL162722A (en) 2013-09-30
US7553623B2 (en) 2009-06-30
US20090275044A1 (en) 2009-11-05
DE60311961D1 (de) 2007-04-05
US20050118568A1 (en) 2005-06-02
EP2913407B1 (de) 2017-11-01
ES2654909T3 (es) 2018-02-15
JP5204132B2 (ja) 2013-06-05
JP4558322B2 (ja) 2010-10-06
EA200400919A1 (ru) 2005-02-24
EP1715062A2 (de) 2006-10-25
WO2003057914A3 (en) 2004-02-26
EP2267155A2 (de) 2010-12-29
WO2003057914A2 (en) 2003-07-17
CY1106621T1 (el) 2012-01-25
AU2003201639C1 (en) 2009-02-26
CN1639357A (zh) 2005-07-13
ES2282599T3 (es) 2007-10-16
EP2267155A3 (de) 2011-06-08
EA006975B1 (ru) 2006-06-30
AU2003201639A1 (en) 2003-07-24
DK2913407T3 (en) 2018-01-15
SI1463839T1 (sl) 2007-08-31
JP2005514038A (ja) 2005-05-19
EP2267155B1 (de) 2013-03-13
DK1463839T3 (da) 2007-07-02
EP1715062A3 (de) 2007-07-11
EP2267155B2 (de) 2016-09-07
NZ533703A (en) 2006-05-26
EP2272988A2 (de) 2011-01-12
JP2010131020A (ja) 2010-06-17
BR0306723A (pt) 2004-12-21
EP2913407A1 (de) 2015-09-02
US7812144B2 (en) 2010-10-12
US20130309658A1 (en) 2013-11-21
EP1715062B1 (de) 2015-03-11
CA2472026A1 (en) 2003-07-17
NO20042769L (no) 2004-10-04
EP1463839A2 (de) 2004-10-06
DE60311961T2 (de) 2007-10-18
MXPA04006440A (es) 2005-03-31
EP1463839B1 (de) 2007-02-21
IL162722A0 (en) 2005-11-20
US20090253124A1 (en) 2009-10-08
US8420314B2 (en) 2013-04-16
EP2272988A3 (de) 2011-06-15
AU2008205436A1 (en) 2008-09-04
HK1065827A1 (en) 2005-03-04
PT1463839E (pt) 2007-05-31
AU2003201639B2 (en) 2008-05-15

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