ATE356202T1 - Attenuierte stabile tollwutvirusmutante und lebende impfstoffe - Google Patents

Attenuierte stabile tollwutvirusmutante und lebende impfstoffe

Info

Publication number
ATE356202T1
ATE356202T1 AT99973064T AT99973064T ATE356202T1 AT E356202 T1 ATE356202 T1 AT E356202T1 AT 99973064 T AT99973064 T AT 99973064T AT 99973064 T AT99973064 T AT 99973064T AT E356202 T1 ATE356202 T1 AT E356202T1
Authority
AT
Austria
Prior art keywords
attenuated
stable
rabies virus
live vaccines
virus mutant
Prior art date
Application number
AT99973064T
Other languages
English (en)
Inventor
Teshome Mebatsion
Karl Klaus Conzelmann
Original Assignee
Intervet Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet Int Bv filed Critical Intervet Int Bv
Application granted granted Critical
Publication of ATE356202T1 publication Critical patent/ATE356202T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20111—Lyssavirus, e.g. rabies virus
    • C12N2760/20122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20111—Lyssavirus, e.g. rabies virus
    • C12N2760/20161—Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT99973064T 1998-11-27 1999-11-19 Attenuierte stabile tollwutvirusmutante und lebende impfstoffe ATE356202T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98204001 1998-11-27

Publications (1)

Publication Number Publication Date
ATE356202T1 true ATE356202T1 (de) 2007-03-15

Family

ID=8234392

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99973064T ATE356202T1 (de) 1998-11-27 1999-11-19 Attenuierte stabile tollwutvirusmutante und lebende impfstoffe

Country Status (16)

Country Link
US (1) US6719981B1 (de)
EP (1) EP1131414B1 (de)
AR (1) AR021406A1 (de)
AT (1) ATE356202T1 (de)
AU (1) AU1386100A (de)
BR (1) BR9915703B1 (de)
CA (1) CA2352231C (de)
CY (1) CY1106570T1 (de)
DE (1) DE69935445T2 (de)
DK (1) DK1131414T3 (de)
ES (1) ES2283150T3 (de)
ID (1) ID28968A (de)
IL (2) IL143149A0 (de)
PT (1) PT1131414E (de)
TR (1) TR200101445T2 (de)
WO (1) WO2000032755A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2257505T3 (es) * 2001-04-23 2006-08-01 Akzo Nobel N.V. Mutantes de virus de la rabia atenuados y vacunas vivas correspondientes.
NZ531025A (en) 2001-07-20 2005-08-26 Univ Georgia Res Found Vaccine comprising a mutant rabies virus N protein which has an amino acid other than serine at position 389 and possibly one or more other mutations within the N protein
CN101287838B (zh) 2005-10-14 2016-03-30 美国政府健康及人类服务部，疾病控制和预防中心 狂犬病病毒组合物和方法
US7785874B2 (en) * 2007-01-11 2010-08-31 The Salk Institute For Biological Studies Compositions and methods for monosynaptic transport
TW200907058A (en) * 2007-05-30 2009-02-16 Wyeth Corp Raccoon poxvirus expressing rabies glycoproteins
US10849975B2 (en) 2011-02-03 2020-12-01 Thomas Jefferson University Multivalent vaccines for rabies virus and filoviruses
CN103865889B (zh) * 2014-04-03 2015-02-25 深圳市卫光生物制品股份有限公司 狂犬病病毒ctn鸡胚细胞适应株
US11041170B2 (en) 2016-04-04 2021-06-22 Thomas Jefferson University Multivalent vaccines for rabies virus and coronaviruses

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2580176B1 (fr) * 1985-04-12 1988-02-26 Centre Nat Rech Scient Vaccin antirabique avirulent
FR2633832B1 (fr) * 1988-07-05 1991-05-31 Virbac Vaccin antirabique avirulent
FR2693655B1 (fr) * 1992-07-20 1994-10-14 Virbac Vaccin antirabique avirulent.
SE0002498D0 (sv) 2000-07-03 2000-07-03 Stefan Schwartz Papillomavirus vaccine
WO2003050398A1 (en) 2001-12-10 2003-06-19 Donaldson Company, Inc. Exhaust treatment control system for an internal combustion engine
DE102004009653A1 (de) 2004-02-27 2005-09-22 Cycos Ag Kommunikationsserver und Verfahren zum Aufbau und Betrieb einer Konferenz-Kommunikationsverbindung

Also Published As

Publication number Publication date
IL143149A (en) 2007-12-03
CA2352231C (en) 2010-06-01
PT1131414E (pt) 2007-04-30
AR021406A1 (es) 2002-07-17
CA2352231A1 (en) 2000-06-08
IL143149A0 (en) 2002-04-21
DE69935445T2 (de) 2007-11-29
AU1386100A (en) 2000-06-19
DE69935445D1 (de) 2007-04-19
ES2283150T3 (es) 2007-10-16
BR9915703B1 (pt) 2012-09-04
DK1131414T3 (da) 2007-06-18
EP1131414A1 (de) 2001-09-12
TR200101445T2 (tr) 2001-10-22
CY1106570T1 (el) 2012-01-25
US6719981B1 (en) 2004-04-13
EP1131414B1 (de) 2007-03-07
BR9915703A (pt) 2001-08-14
ID28968A (id) 2001-07-19
WO2000032755A1 (en) 2000-06-08

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