DK1131414T3 - Stabile, svækkede rabiesvirusmutanter og levende vacciner deraf - Google Patents

Stabile, svækkede rabiesvirusmutanter og levende vacciner deraf

Info

Publication number
DK1131414T3
DK1131414T3 DK99973064T DK99973064T DK1131414T3 DK 1131414 T3 DK1131414 T3 DK 1131414T3 DK 99973064 T DK99973064 T DK 99973064T DK 99973064 T DK99973064 T DK 99973064T DK 1131414 T3 DK1131414 T3 DK 1131414T3
Authority
DK
Denmark
Prior art keywords
stable
rabies virus
live vaccines
virus mutants
attenuated rabies
Prior art date
Application number
DK99973064T
Other languages
English (en)
Inventor
Teshome Mebatsion
Karl Klaus Conzelmann
Original Assignee
Intervet Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet Int Bv filed Critical Intervet Int Bv
Application granted granted Critical
Publication of DK1131414T3 publication Critical patent/DK1131414T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20111—Lyssavirus, e.g. rabies virus
    • C12N2760/20122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20111—Lyssavirus, e.g. rabies virus
    • C12N2760/20161—Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK99973064T 1998-11-27 1999-11-19 Stabile, svækkede rabiesvirusmutanter og levende vacciner deraf DK1131414T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98204001 1998-11-27
PCT/EP1999/009101 WO2000032755A1 (en) 1998-11-27 1999-11-19 Stable, attenuated rabies virus mutants and live vaccines thereof

Publications (1)

Publication Number Publication Date
DK1131414T3 true DK1131414T3 (da) 2007-06-18

Family

ID=8234392

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99973064T DK1131414T3 (da) 1998-11-27 1999-11-19 Stabile, svækkede rabiesvirusmutanter og levende vacciner deraf

Country Status (16)

Country Link
US (1) US6719981B1 (da)
EP (1) EP1131414B1 (da)
AR (1) AR021406A1 (da)
AT (1) ATE356202T1 (da)
AU (1) AU1386100A (da)
BR (1) BR9915703B1 (da)
CA (1) CA2352231C (da)
CY (1) CY1106570T1 (da)
DE (1) DE69935445T2 (da)
DK (1) DK1131414T3 (da)
ES (1) ES2283150T3 (da)
ID (1) ID28968A (da)
IL (2) IL143149A0 (da)
PT (1) PT1131414E (da)
TR (1) TR200101445T2 (da)
WO (1) WO2000032755A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1253197E (pt) 2001-04-23 2006-06-30 Akzo Nobel Nv Virus da raiva recombinante atenuado e suas vacinas vivas
MXPA04000589A (es) 2001-07-20 2005-06-17 Univ Georgia Res Found Virus de la rabia atenuado con mutacion de nucleoproteina en el sitio de fosforilacion para vacunacion contra la rabia y terapia genetica en el snc.
CA2943039C (en) 2005-10-14 2018-11-06 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Rabies virus compositions and methods
US7785874B2 (en) * 2007-01-11 2010-08-31 The Salk Institute For Biological Studies Compositions and methods for monosynaptic transport
TW200907058A (en) 2007-05-30 2009-02-16 Wyeth Corp Raccoon poxvirus expressing rabies glycoproteins
US10849975B2 (en) 2011-02-03 2020-12-01 Thomas Jefferson University Multivalent vaccines for rabies virus and filoviruses
CN103865889B (zh) * 2014-04-03 2015-02-25 深圳市卫光生物制品股份有限公司 狂犬病病毒ctn鸡胚细胞适应株
WO2017176596A1 (en) 2016-04-04 2017-10-12 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Multivalent vaccines for rabies virus and coronaviruses

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2580176B1 (fr) * 1985-04-12 1988-02-26 Centre Nat Rech Scient Vaccin antirabique avirulent
FR2633832B1 (fr) * 1988-07-05 1991-05-31 Virbac Vaccin antirabique avirulent
FR2693655B1 (fr) * 1992-07-20 1994-10-14 Virbac Vaccin antirabique avirulent.
SE0002498D0 (sv) 2000-07-03 2000-07-03 Stefan Schwartz Papillomavirus vaccine
US20050247051A1 (en) 2001-12-10 2005-11-10 Donaldson Company, Inc. Exhaust treatment control system for an internal combustion engine
DE102004009653A1 (de) 2004-02-27 2005-09-22 Cycos Ag Kommunikationsserver und Verfahren zum Aufbau und Betrieb einer Konferenz-Kommunikationsverbindung

Also Published As

Publication number Publication date
TR200101445T2 (tr) 2001-10-22
DE69935445T2 (de) 2007-11-29
DE69935445D1 (de) 2007-04-19
CA2352231A1 (en) 2000-06-08
CA2352231C (en) 2010-06-01
WO2000032755A1 (en) 2000-06-08
ATE356202T1 (de) 2007-03-15
BR9915703A (pt) 2001-08-14
BR9915703B1 (pt) 2012-09-04
AR021406A1 (es) 2002-07-17
PT1131414E (pt) 2007-04-30
EP1131414A1 (en) 2001-09-12
IL143149A0 (en) 2002-04-21
ID28968A (id) 2001-07-19
EP1131414B1 (en) 2007-03-07
CY1106570T1 (el) 2012-01-25
ES2283150T3 (es) 2007-10-16
AU1386100A (en) 2000-06-19
IL143149A (en) 2007-12-03
US6719981B1 (en) 2004-04-13

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