ATE356209T1 - Mutanten des thyroid-stimulierenden hormons - Google Patents

Mutanten des thyroid-stimulierenden hormons

Info

Publication number
ATE356209T1
ATE356209T1 AT98948422T AT98948422T ATE356209T1 AT E356209 T1 ATE356209 T1 AT E356209T1 AT 98948422 T AT98948422 T AT 98948422T AT 98948422 T AT98948422 T AT 98948422T AT E356209 T1 ATE356209 T1 AT E356209T1
Authority
AT
Austria
Prior art keywords
tsh
mutant
thyroid
methods
subunits
Prior art date
Application number
AT98948422T
Other languages
English (en)
Inventor
Bruce D Weintraub
Mariusz W Szkudlinski
Original Assignee
Univ Maryland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Maryland filed Critical Univ Maryland
Application granted granted Critical
Publication of ATE356209T1 publication Critical patent/ATE356209T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT98948422T 1997-09-22 1998-09-22 Mutanten des thyroid-stimulierenden hormons ATE356209T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93947297A 1997-09-22 1997-09-22

Publications (1)

Publication Number Publication Date
ATE356209T1 true ATE356209T1 (de) 2007-03-15

Family

ID=25473237

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98948422T ATE356209T1 (de) 1997-09-22 1998-09-22 Mutanten des thyroid-stimulierenden hormons

Country Status (10)

Country Link
US (1) US20040266665A1 (de)
EP (2) EP1816199A1 (de)
JP (1) JP2001517445A (de)
KR (4) KR100642602B1 (de)
CN (1) CN1277633A (de)
AT (1) ATE356209T1 (de)
AU (1) AU758156B2 (de)
CA (1) CA2302993A1 (de)
DE (1) DE69837271T2 (de)
WO (1) WO1999015665A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1115866A1 (de) * 1998-09-22 2001-07-18 University of Maryland at Baltimore Mutanten der cysteinknoten-wachstumsfaktoren familie
KR100423735B1 (ko) * 2000-11-13 2004-03-20 학교법인 포항공과대학교 그레이브스 질환에 길항작용을 하는 펩타이드 및 그의 용도
US20050171017A1 (en) * 2003-12-05 2005-08-04 Kelly James D. Methods for treating inflammation using thyroid stimulating hormone
BRPI0509469A (pt) * 2004-03-31 2007-09-11 Trophogen Inc superagonistas do hormÈnio glicoprotéico humano e uso dos mesmos
JP5727693B2 (ja) 2005-12-23 2015-06-03 ジェームス ディー． ケリー 代謝症候群を処置するための改善された甲状腺刺激ホルモン受容体ポリペプチドアゴニストグリコフォーム
JP2010503689A (ja) * 2006-09-19 2010-02-04 ジェンザイム コーポレーション 甲状腺刺激ホルモン（ｔｓｈ）の治療的投与のための配合物
GB0725201D0 (en) * 2007-12-24 2008-01-30 Asterion Ltd Peptide fusion proteins
GB0808402D0 (en) * 2008-05-09 2008-06-18 Asterion Ltd Tsh
US20110052591A1 (en) * 2009-08-28 2011-03-03 Board Of Regents Of The University Of Texas System Variants of Thyroid Stimulating Hormone Beta
US10358574B2 (en) 2016-07-01 2019-07-23 Hercules Llc Coating compositions containing lactam-functionalized polymer
US20230220026A1 (en) * 2022-01-12 2023-07-13 National Yang Ming Chiao Tung University Nucleic acid carrier for producing the single-chain vegf fusion protein with high physiological stability and dimeric efficiency, preparation method thereof, and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980286A (en) * 1985-07-05 1990-12-25 Whitehead Institute For Biomedical Research In vivo introduction and expression of foreign genetic material in epithelial cells
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
CA2053864C (en) * 1989-02-21 2001-11-20 Irving Boime Modified forms of reproductive hormones
DK0725795T3 (da) * 1994-08-12 2004-05-17 Univ Washington Enkelt-kæde form af glycoprotein-hormon-kvartetten
US6361992B1 (en) * 1996-05-08 2002-03-26 The United States Of America As Represented By The Department Of Health And Human Services Thyroid stimulating hormone superagonists

Also Published As

Publication number Publication date
WO1999015665A2 (en) 1999-04-01
US20040266665A1 (en) 2004-12-30
KR100642602B1 (ko) 2006-11-10
DE69837271D1 (de) 2007-04-19
KR20050085968A (ko) 2005-08-29
EP1017817A2 (de) 2000-07-12
AU9499898A (en) 1999-04-12
KR100642592B1 (ko) 2006-11-13
DE69837271T2 (de) 2007-11-22
CA2302993A1 (en) 1999-04-01
KR20050085970A (ko) 2005-08-29
KR100642586B1 (ko) 2006-11-10
KR100642599B1 (ko) 2006-11-10
EP1816199A1 (de) 2007-08-08
KR20010030661A (ko) 2001-04-16
CN1277633A (zh) 2000-12-20
EP1017817B1 (de) 2007-03-07
WO1999015665A3 (en) 1999-05-20
AU758156B2 (en) 2003-03-13
JP2001517445A (ja) 2001-10-09
KR20050085969A (ko) 2005-08-29

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