ATE356814T1 - Heterozyclische verbindungen, ihr herstellungsverfahren und diese enthaltende pharmazeutische zusammensetzungen - Google Patents

Heterozyclische verbindungen, ihr herstellungsverfahren und diese enthaltende pharmazeutische zusammensetzungen

Info

Publication number: ATE356814T1
Authority: AT; Austria
Prior art keywords: pharmaceutical compositions; production process; compositions containing; heterocyclic compounds; description
Prior art date: 1997-05-16

Application number

AT98925703T

Other languages

English (en)

Inventor

Gerald Guillaumet

Marie-Claude Viaud

Ahmed Mamai

Isabelle Charton

Pierre Renard

Caroline Bennejean

Beatrice Guardiola

Philippe Daubos

Original Assignee

Servier Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-05-16

Filing date

1998-05-14

Publication date

2007-04-15

1998-05-14 Application filed by Servier Lab filed Critical Servier Lab

2007-04-15 Application granted granted Critical

2007-04-15 Publication of ATE356814T1 publication Critical patent/ATE356814T1/de

Links

150000002391 heterocyclic compounds Chemical class 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229940126601 medicinal product Drugs 0.000 abstract 1
230000001193 melatoninergic effect Effects 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/08—Six-membered rings

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Hematology (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Obesity (AREA)
Psychology (AREA)
Dermatology (AREA)
Anesthesiology (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Emergency Medicine (AREA)
Reproductive Health (AREA)
Child & Adolescent Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Pyrane Compounds (AREA)

AT98925703T 1997-05-16 1998-05-14 Heterozyclische verbindungen, ihr herstellungsverfahren und diese enthaltende pharmazeutische zusammensetzungen ATE356814T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9706019A FR2763335B1 (fr)	1997-05-16	1997-05-16	Nouveaux composes heterocycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number	Publication Date
ATE356814T1 true ATE356814T1 (de)	2007-04-15

Family

ID=9506957

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98925703T ATE356814T1 (de)	1997-05-16	1998-05-14	Heterozyclische verbindungen, ihr herstellungsverfahren und diese enthaltende pharmazeutische zusammensetzungen

Country Status (20)

Country	Link
US (2)	US6313160B1 (de)
EP (1)	EP0998471B1 (de)
JP (1)	JP2002510290A (de)
CN (1)	CN1139584C (de)
AT (1)	ATE356814T1 (de)
AU (1)	AU741753B2 (de)
BR (1)	BR9809643A (de)
CA (1)	CA2289599C (de)
CY (1)	CY1106545T1 (de)
DE (1)	DE69837334T2 (de)
DK (1)	DK0998471T3 (de)
ES (1)	ES2285775T3 (de)
FR (1)	FR2763335B1 (de)
HU (1)	HUP0003127A3 (de)
NO (1)	NO324562B1 (de)
NZ (1)	NZ500952A (de)
PL (1)	PL197156B1 (de)
PT (1)	PT998471E (de)
WO (1)	WO1998052935A1 (de)
ZA (1)	ZA984114B (de)

Families Citing this family (11)

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WO2001042234A1 (en) *	1999-12-13	2001-06-14	Chugai Seiyaku Kabushiki Kaisha	3-methyl-chroman and -thiochroman derivatives
DE10344412A1 (de) *	2003-09-25	2005-05-19	Röhm GmbH & Co. KG	Polymernetzwerke
BRPI0610027A2 (pt) *	2005-04-22	2010-05-18	Wyeth Corp	derivados de cromano e cromeno e usos dos mesmos
CN1891687B (zh) *	2005-07-08	2011-08-03	中国医学科学院医药生物技术研究所	微生物来源的炎症因子受体拮抗活性化合物及其应用
DK2123265T3 (da) *	2008-05-23	2012-09-03	Novaera S R L	Endipalenformuleringer til behandling af psoriasis
ES2782357T3 (es)	2009-11-03	2020-09-14	Fosun Orinove Pharmatech Inc	Inhibidores de IRE 1 alfa
KR102022154B1 (ko) *	2016-11-24	2019-09-18	한양대학교 산학협력단	MBD2-p66α(GATAD2A)의 상호작용을 억제하는 화합물을 포함하는 암 전이 억제 및 암 질환 예방 및 치료용 조성물
US10052326B1 (en)	2017-10-12	2018-08-21	King Saud University	Antihepatotoxic agents
CN111960985A (zh) *	2018-08-08	2020-11-20	中国人民解放军总医院	抗肿瘤化合物
CN120058664B (zh) *	2025-02-26	2025-10-24	宜昌市中心人民医院(三峡大学第一临床医学院、三峡大学附属中心人民医院)	一种褪黑素受体激动剂及其制备方法和用途

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US4046762A (en) *	1972-10-20	1977-09-06	Instituto Luso Farmaco D'italia S.R.L.	Esters and amides of 3-aryl-1,4 benzodioxan-2-carboxylic acids
GB1598128A (en) *	1977-03-17	1981-09-16	Shell Int Research	Benzopyran carboxamides having lipogenesis-inhibiting properties
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FR2680366B1 (fr) *	1991-08-13	1995-01-20	Adir	Nouveaux derives d'arylethylamines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
FR2696453B1 (fr) *	1992-10-02	1994-12-23	Adir	Nouveaux arylalkyl(thio)amides, leur procédé de préparation, et les compositions pharmaceutiques qui les contiennent.
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FR2704857B1 (fr) *	1993-05-07	1995-06-23	Adir	Nouvelles benzodioxines substituées, leur procédé de préparation et les compositions pharmaceutiques les contenant.
GB9326192D0 (en) *	1993-12-22	1994-02-23	Glaxo Group Ltd	Chemical compounds
FR2716680B1 (fr) *	1994-02-25	1996-04-05	Adir	Nouveaux dérivés de benzodioxane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
JPH07242655A (ja) *	1994-03-03	1995-09-19	Taiho Yakuhin Kogyo Kk	１，４−ベンゾジオキサン誘導体
JPH07242543A (ja) *	1994-03-03	1995-09-19	Taiho Yakuhin Kogyo Kk	肝疾患治療剤
GB9407919D0 (en) *	1994-04-21	1994-06-15	Glaxo Group Ltd	Chemical compounds
FR2725985B1 (fr) *	1994-10-21	1996-11-15	Adir	Nouveaux composes tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2729147A1 (fr) *	1995-01-11	1996-07-12	Adir	Nouveaux composes (hetero) cycliques alkyles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2732969B1 (fr) *	1995-04-14	1997-05-16	Adir	Nouveaux composes pyridiniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2734814B1 (fr) *	1995-05-31	1997-07-04	Adir	Nouveaux composes alkoxy-aryles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2734816B1 (fr) *	1995-05-31	1997-07-04	Adir	Nouveaux aryl (alkyl) propylamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2734815B1 (fr) *	1995-05-31	1997-07-04	Adir	Nouveaux composes arylalkyl (thio) carboxamides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent

1997
- 1997-05-16 FR FR9706019A patent/FR2763335B1/fr not_active Expired - Fee Related
1998
- 1998-05-14 DK DK98925703T patent/DK0998471T3/da active
- 1998-05-14 CA CA002289599A patent/CA2289599C/fr not_active Expired - Fee Related
- 1998-05-14 DE DE69837334T patent/DE69837334T2/de not_active Expired - Fee Related
- 1998-05-14 NZ NZ500952A patent/NZ500952A/en unknown
- 1998-05-14 HU HU0003127A patent/HUP0003127A3/hu unknown
- 1998-05-14 PL PL336857A patent/PL197156B1/pl unknown
- 1998-05-14 AU AU77723/98A patent/AU741753B2/en not_active Ceased
- 1998-05-14 US US09/423,745 patent/US6313160B1/en not_active Expired - Fee Related
- 1998-05-14 EP EP98925703A patent/EP0998471B1/de not_active Expired - Lifetime
- 1998-05-14 PT PT98925703T patent/PT998471E/pt unknown
- 1998-05-14 WO PCT/FR1998/000954 patent/WO1998052935A1/fr not_active Ceased
- 1998-05-14 AT AT98925703T patent/ATE356814T1/de not_active IP Right Cessation
- 1998-05-14 BR BR9809643-5A patent/BR9809643A/pt not_active Application Discontinuation
- 1998-05-14 JP JP55002898A patent/JP2002510290A/ja not_active Ceased
- 1998-05-14 CN CNB988062844A patent/CN1139584C/zh not_active Expired - Fee Related
- 1998-05-14 ES ES98925703T patent/ES2285775T3/es not_active Expired - Lifetime
- 1998-05-15 ZA ZA984114A patent/ZA984114B/xx unknown
1999
- 1999-11-15 NO NO19995594A patent/NO324562B1/no unknown
2001
- 2001-08-28 US US09/941,016 patent/US6602903B2/en not_active Expired - Fee Related
2007
- 2007-04-26 CY CY20071100565T patent/CY1106545T1/el unknown

Also Published As

Publication number	Publication date
JP2002510290A (ja)	2002-04-02
PL336857A1 (en)	2000-07-17
DK0998471T3 (da)	2007-07-02
CN1260789A (zh)	2000-07-19
AU741753B2 (en)	2001-12-06
NO995594L (no)	2000-01-14
FR2763335B1 (fr)	2000-11-24
EP0998471A1 (de)	2000-05-10
CA2289599A1 (fr)	1998-11-26
AU7772398A (en)	1998-12-11
US6313160B1 (en)	2001-11-06
EP0998471B1 (de)	2007-03-14
NZ500952A (en)	2002-03-01
DE69837334T2 (de)	2008-01-10
WO1998052935A1 (fr)	1998-11-26
NO324562B1 (no)	2007-11-19
PT998471E (pt)	2007-06-05
CN1139584C (zh)	2004-02-25
CA2289599C (fr)	2005-12-06
FR2763335A1 (fr)	1998-11-20
CY1106545T1 (el)	2012-01-25
US20020052400A1 (en)	2002-05-02
HUP0003127A2 (hu)	2002-05-29
HUP0003127A3 (en)	2002-12-28
ES2285775T3 (es)	2007-11-16
ZA984114B (en)	1998-11-24
NO995594D0 (no)	1999-11-15
US6602903B2 (en)	2003-08-05
PL197156B1 (pl)	2008-03-31
DE69837334D1 (de)	2007-04-26
HK1028028A1 (en)	2001-02-02
BR9809643A (pt)	2000-10-03

Legal Events

Date

Code

Title

Description

2007-09-15

UEP

Publication of translation of european patent specification

Ref document number: 0998471

Country of ref document: EP

2010-02-15

REN

Ceased due to non-payment of the annual fee

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DE59807405D1 (de)	2003-04-10	Acylsulfamoylbenzoesäureamide, diese enthaltende nutzpflanzenschützende mittel und verfahren zu ihrer herstellung
TR200003478T2 (tr)	2001-03-21	Antikanser maddeleri olarak faydalı izotiyazol türevleri
FR2671348B1 (fr)	1993-03-26	Nouvelles phenylimidazolidines, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant.
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