ATE356865T1 - Untersuchungsverfahren für protein-protein- interaktion - Google Patents

Untersuchungsverfahren für protein-protein- interaktion

Info

Publication number
ATE356865T1
ATE356865T1 AT99915053T AT99915053T ATE356865T1 AT E356865 T1 ATE356865 T1 AT E356865T1 AT 99915053 T AT99915053 T AT 99915053T AT 99915053 T AT99915053 T AT 99915053T AT E356865 T1 ATE356865 T1 AT E356865T1
Authority
AT
Austria
Prior art keywords
protein
study methods
interaction
protein interaction
study
Prior art date
Application number
AT99915053T
Other languages
English (en)
Inventor
Michael Phillip Weiner
Richard Gordon Buckholz
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/049,325 external-priority patent/US6332897B1/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE356865T1 publication Critical patent/ATE356865T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1055Protein x Protein interaction, e.g. two hybrid selection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00306Reactor vessels in a multiple arrangement
    • B01J2219/00313Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315Microtiter plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00659Two-dimensional arrays
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT99915053T 1998-03-26 1999-03-26 Untersuchungsverfahren für protein-protein- interaktion ATE356865T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7948098P 1998-03-26 1998-03-26
US09/049,325 US6332897B1 (en) 1998-03-27 1998-03-27 Assay methods

Publications (1)

Publication Number Publication Date
ATE356865T1 true ATE356865T1 (de) 2007-04-15

Family

ID=26727069

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99915053T ATE356865T1 (de) 1998-03-26 1999-03-26 Untersuchungsverfahren für protein-protein- interaktion

Country Status (10)

Country Link
EP (1) EP1315958B1 (de)
JP (1) JP4440464B2 (de)
AT (1) ATE356865T1 (de)
AU (1) AU775227B2 (de)
CA (1) CA2325447C (de)
DE (1) DE69935539T2 (de)
ES (1) ES2284245T3 (de)
IL (2) IL138353A0 (de)
IS (1) IS2530B (de)
WO (1) WO1999049294A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6794127B1 (en) 1997-06-16 2004-09-21 Diversa Corporation Capillary array-based sample screening
US6972183B1 (en) 1997-06-16 2005-12-06 Diversa Corporation Capillary array-based enzyme screening
AU1796101A (en) * 1999-11-22 2001-06-04 Diversa Corporation Capillary array-based sample screening
US20030032592A1 (en) * 2000-12-21 2003-02-13 Cimbora Daniel M. Protein-protein interactions
CA2542182A1 (en) * 2003-10-09 2005-04-28 Ecole Polytechnique Federale De Lausanne Method for identification of suitable fragmentation sites in a reporter protein
JP4554269B2 (ja) * 2004-05-13 2010-09-29 財団法人かずさディー・エヌ・エー研究所 液体培養による大腸菌ツーハイブリッドシステム
US20110165583A1 (en) * 2008-09-02 2011-07-07 Lupin Limited Vector for identification, selection and expression of recombinants
BR112018074472A2 (pt) 2016-05-27 2019-03-19 Synthex, Inc. interfaces proteicas
GB2584210B (en) 2017-11-22 2022-03-16 Synthex Inc Peptides for inhibiting RAD51

Also Published As

Publication number Publication date
JP2003524371A (ja) 2003-08-19
IS5620A (is) 2000-09-08
CA2325447C (en) 2007-08-21
ES2284245T3 (es) 2007-11-01
AU775227B2 (en) 2004-07-22
AU3365899A (en) 1999-10-18
IL138353A0 (en) 2001-10-31
EP1315958A4 (de) 2005-01-05
WO1999049294A2 (en) 1999-09-30
IS2530B (is) 2009-07-15
JP4440464B2 (ja) 2010-03-24
DE69935539D1 (de) 2007-04-26
EP1315958A2 (de) 2003-06-04
EP1315958B1 (de) 2007-03-14
IL138353A (en) 2007-05-15
WO1999049294A3 (en) 2003-03-20
DE69935539T2 (de) 2007-12-06
CA2325447A1 (en) 1999-09-30

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