ATE357238T1 - Verfahren zur herstellung von selbstinduzierender synthase - Google Patents

Verfahren zur herstellung von selbstinduzierender synthase

Info

Publication number
ATE357238T1
ATE357238T1 AT99941978T AT99941978T ATE357238T1 AT E357238 T1 ATE357238 T1 AT E357238T1 AT 99941978 T AT99941978 T AT 99941978T AT 99941978 T AT99941978 T AT 99941978T AT E357238 T1 ATE357238 T1 AT E357238T1
Authority
AT
Austria
Prior art keywords
synthase
useful
inducing
autoinducer
producing self
Prior art date
Application number
AT99941978T
Other languages
English (en)
Inventor
John E Cronan Jr
Bryce V Plapp
E Peter Greenberg
Matthew R Parsek
Original Assignee
Univ Iowa Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Iowa Res Found filed Critical Univ Iowa Res Found
Application granted granted Critical
Publication of ATE357238T1 publication Critical patent/ATE357238T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • C07H19/20Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C07H19/207Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids the phosphoric or polyphosphoric acids being esterified by a further hydroxylic compound, e.g. flavine adenine dinucleotide or nicotinamide-adenine dinucleotide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/25Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving enzymes not classifiable in groups C12Q1/26 - C12Q1/66
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/832Drug, bio-affecting and body treating compositions involving bacterial toxin that has modified amino acid sequence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Indole Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT99941978T 1998-07-31 1999-07-29 Verfahren zur herstellung von selbstinduzierender synthase ATE357238T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9498898P 1998-07-31 1998-07-31
US09/227,488 US6723321B2 (en) 1998-07-31 1999-01-06 Autoinducer synthase modulating compounds and uses thereof

Publications (1)

Publication Number Publication Date
ATE357238T1 true ATE357238T1 (de) 2007-04-15

Family

ID=26789418

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99941978T ATE357238T1 (de) 1998-07-31 1999-07-29 Verfahren zur herstellung von selbstinduzierender synthase

Country Status (7)

Country Link
US (2) US6723321B2 (de)
EP (1) EP1100513B1 (de)
AT (1) ATE357238T1 (de)
AU (1) AU5544999A (de)
CA (1) CA2337710A1 (de)
DE (1) DE69935597T2 (de)
WO (1) WO2000006177A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6720415B2 (en) * 1998-12-02 2004-04-13 Princeton University Compositions and methods for regulating bacterial pathogenesis
US7326542B2 (en) * 1998-12-02 2008-02-05 Princeton University Compositions and methods for regulating bacterial pathogenesis
US7651699B2 (en) * 2001-01-08 2010-01-26 Pathway Intermediates Limited Autoinducer compounds and their uses
CN100350036C (zh) * 2001-04-27 2007-11-21 宝洁公司 用于控制生物膜的装置和方法
DE102011015844A1 (de) * 2011-03-30 2012-10-04 Friedrich-Schiller-Universität Jena Verfahren zur Steuerung der Synthese extrazellulärer Biopolymere, insbesondere bakterieller Nanocellulose
WO2012174511A1 (en) 2011-06-16 2012-12-20 The Florida International University Board Of Trustees 2-methylthiopyrrolidines and their use for modulating bacterial quorum sensing
WO2017074952A1 (en) 2015-10-26 2017-05-04 The Penn State Research Foundation Biofilms, components and methods of use to reduce biofouling and contamination
CN115656117B (zh) * 2022-09-20 2025-09-12 浙江大学杭州国际科创中心 基于簇发光的监测溶菌酶淀粉样纤维化进程的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60180599A (ja) * 1984-02-27 1985-09-14 Nippon Zeon Co Ltd S−アデノシル−l−ホモシステインの製造法
US5591872A (en) 1993-08-09 1997-01-07 The University Of Iowa Research Foundation Autoinducer molecule
US6020121A (en) 1995-09-29 2000-02-01 Microcide Pharmaceuticals, Inc. Inhibitors of regulatory pathways

Also Published As

Publication number Publication date
US6723321B2 (en) 2004-04-20
CA2337710A1 (en) 2000-02-10
AU5544999A (en) 2000-02-21
DE69935597T2 (de) 2007-11-29
US20040152660A1 (en) 2004-08-05
DE69935597D1 (de) 2007-05-03
EP1100513B1 (de) 2007-03-21
EP1100513A1 (de) 2001-05-23
WO2000006177A1 (en) 2000-02-10
US20030054512A1 (en) 2003-03-20

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Legal Events

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