ATE357448T1 - Benzoxazinonderivative, deren herstellung und verwendung - Google Patents

Benzoxazinonderivative, deren herstellung und verwendung

Info

Publication number
ATE357448T1
ATE357448T1 AT01988720T AT01988720T ATE357448T1 AT E357448 T1 ATE357448 T1 AT E357448T1 AT 01988720 T AT01988720 T AT 01988720T AT 01988720 T AT01988720 T AT 01988720T AT E357448 T1 ATE357448 T1 AT E357448T1
Authority
AT
Austria
Prior art keywords
preparation
benzoxazinone derivatives
benzoxazinone
derivatives
Prior art date
Application number
AT01988720T
Other languages
English (en)
Inventor
Christopher N Johnson
Harshad Kantilal Rami
Geoffrey Stemp
Kevin Thewlis
Mervyn Thompson
Antonio Kuok K Vong
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0026224A external-priority patent/GB0026224D0/en
Priority claimed from GB0111858A external-priority patent/GB0111858D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Application granted granted Critical
Publication of ATE357448T1 publication Critical patent/ATE357448T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT01988720T 2000-10-26 2001-10-22 Benzoxazinonderivative, deren herstellung und verwendung ATE357448T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0026224A GB0026224D0 (en) 2000-10-26 2000-10-26 Novel compounds
GB0111858A GB0111858D0 (en) 2001-05-15 2001-05-15 Novel compounds

Publications (1)

Publication Number Publication Date
ATE357448T1 true ATE357448T1 (de) 2007-04-15

Family

ID=26245199

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01988720T ATE357448T1 (de) 2000-10-26 2001-10-22 Benzoxazinonderivative, deren herstellung und verwendung

Country Status (20)

Country Link
US (1) US6939871B2 (de)
EP (1) EP1330460B1 (de)
JP (1) JP4242643B2 (de)
KR (1) KR20030051747A (de)
CN (1) CN1478092A (de)
AR (1) AR034174A1 (de)
AT (1) ATE357448T1 (de)
AU (1) AU2002224791A1 (de)
BR (1) BR0114881A (de)
CA (1) CA2426706A1 (de)
CZ (1) CZ20031163A3 (de)
DE (1) DE60127434T2 (de)
ES (1) ES2280417T3 (de)
HU (1) HUP0301458A2 (de)
IL (1) IL155520A0 (de)
MX (1) MXPA03003820A (de)
NO (1) NO20031838L (de)
PL (1) PL366378A1 (de)
TW (1) TWI237023B (de)
WO (1) WO2002034754A2 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0203811D0 (en) * 2002-02-18 2002-04-03 Glaxo Group Ltd Compounds
GB0203778D0 (en) * 2002-02-18 2002-04-03 Glaxo Group Ltd Compounds
GB0203804D0 (en) * 2002-02-18 2002-04-03 Glaxo Group Ltd Compounds
GB0209244D0 (en) * 2002-04-23 2002-06-05 Glaxo Group Ltd Compounds
AU2003260882A1 (en) * 2002-09-26 2004-04-19 Warner-Lambert Company Llc Heterocyclic substituted piperazines for the treatment of schizophrenia
BR0315221A (pt) 2002-10-10 2005-08-23 Morphochem Ag Komb Chemie Compostos com atividade antibacteriana
PT1562918E (pt) 2002-11-08 2008-03-12 Hoffmann La Roche Benzoxazinonas substituídas e as suas utilizações
GB0227240D0 (en) * 2002-11-21 2002-12-31 Glaxo Group Ltd Compounds
WO2004062398A1 (ja) 2003-01-10 2004-07-29 Zuiko Corporation 着用物品およびその製造方法
CA2523085A1 (en) * 2003-04-30 2004-11-18 Fmc Corporation Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives
GB0310851D0 (en) * 2003-05-12 2003-06-18 Glaxo Group Ltd Compounds
GB0310849D0 (en) * 2003-05-12 2003-06-18 Glaxo Group Ltd Compounds
GB0316915D0 (en) 2003-07-18 2003-08-20 Glaxo Group Ltd Compounds
KR20070046150A (ko) * 2004-07-28 2007-05-02 아이알엠 엘엘씨 스테로이드 호르몬 핵 수용체의 조절제로서의 화합물 및조성물
WO2007042325A1 (de) * 2005-10-13 2007-04-19 Morphochem Aktiengesellschaft für kombinatorische Chemie 5-chinolinderivate mit antibakterieller aktivität
US8716280B2 (en) 2009-01-21 2014-05-06 Basilea Pharmaceutica Ag Bicyclic antibiotics
TWI487709B (zh) 2009-12-18 2015-06-11 Basilea Pharmaceutica Ag 三環抗生素
ES2596369T3 (es) 2011-06-17 2017-01-09 Basilea Pharmaceutica Ag Antibióticos N-heterotricíclicos
PT3448859T (pt) 2017-03-20 2019-10-25 Forma Therapeutics Inc Composições de pirrolopirrole como ativadores de piruvato quinase (pkr).
ES2989438T3 (es) 2018-09-19 2024-11-26 Novo Nordisk Healthcare Ag Activación de la piruvato cinasa R
US12053458B2 (en) 2018-09-19 2024-08-06 Novo Nordisk Health Care Ag Treating sickle cell disease with a pyruvate kinase R activating compound
CN114615977B (zh) 2019-09-19 2025-01-14 诺沃挪第克健康护理股份公司 丙酮酸激酶r(pkr)活化组合物
US12128035B2 (en) 2021-03-19 2024-10-29 Novo Nordisk Health Care Ag Activating pyruvate kinase R

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2191180T3 (es) 1996-05-29 2003-09-01 Warner Lambert Co Antagonistas de los receptores de la dopamina benzoxazinona d4.
EP0900792B1 (de) * 1997-09-02 2003-10-29 Duphar International Research B.V Piperidin- und Piperazin Derivate als 5-HT1-Rezeptor-Agonisten
TW546299B (en) * 1999-01-07 2003-08-11 Wyeth Corp 3,4-dihydro-2H-benzo[1,4]oxazinyl-methyl-[3-(1H-indol-3-yl)-alkyl]-amines
WO2000040581A1 (en) 1999-01-07 2000-07-13 American Home Products Corporation 3,4-dihydro-2h-benzo[1,4]oxazine derivatives

Also Published As

Publication number Publication date
MXPA03003820A (es) 2003-07-28
WO2002034754A2 (en) 2002-05-02
DE60127434T2 (de) 2007-11-29
AR034174A1 (es) 2004-02-04
HUP0301458A2 (hu) 2003-10-28
CN1478092A (zh) 2004-02-25
BR0114881A (pt) 2003-09-30
TWI237023B (en) 2005-08-01
JP4242643B2 (ja) 2009-03-25
EP1330460B1 (de) 2007-03-21
JP2004516250A (ja) 2004-06-03
CA2426706A1 (en) 2002-05-02
NO20031838D0 (no) 2003-04-24
EP1330460A2 (de) 2003-07-30
IL155520A0 (en) 2003-11-23
CZ20031163A3 (cs) 2004-04-14
PL366378A1 (en) 2005-01-24
KR20030051747A (ko) 2003-06-25
NO20031838L (no) 2003-06-24
WO2002034754A3 (en) 2002-07-11
ES2280417T3 (es) 2007-09-16
US20040063704A1 (en) 2004-04-01
DE60127434D1 (de) 2007-05-03
AU2002224791A1 (en) 2002-05-06
US6939871B2 (en) 2005-09-06

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Legal Events

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