ATE358484T1 - Antidiabetische medikamente - Google Patents

Antidiabetische medikamente

Info

Publication number
ATE358484T1
ATE358484T1 AT99926903T AT99926903T ATE358484T1 AT E358484 T1 ATE358484 T1 AT E358484T1 AT 99926903 T AT99926903 T AT 99926903T AT 99926903 T AT99926903 T AT 99926903T AT E358484 T1 ATE358484 T1 AT E358484T1
Authority
AT
Austria
Prior art keywords
substituted
group
unsubstituted
hydrogen atom
lower alkyl
Prior art date
Application number
AT99926903T
Other languages
English (en)
Inventor
Junichi Shimada
Yoshihisa Ohta
Kotaro Takasaki
Miho Suda
Hideaki Kusaka
Hiroshi Yano
Satoshi Nakanishi
Yuzuru Matsuda
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Application granted granted Critical
Publication of ATE358484T1 publication Critical patent/ATE358484T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
AT99926903T 1998-07-02 1999-07-02 Antidiabetische medikamente ATE358484T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18770598 1998-07-02

Publications (1)

Publication Number Publication Date
ATE358484T1 true ATE358484T1 (de) 2007-04-15

Family

ID=16210732

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99926903T ATE358484T1 (de) 1998-07-02 1999-07-02 Antidiabetische medikamente

Country Status (8)

Country Link
US (1) US6489331B1 (de)
EP (1) EP1092435B1 (de)
AT (1) ATE358484T1 (de)
AU (1) AU4396899A (de)
CA (1) CA2336412C (de)
DE (1) DE69935718T2 (de)
ES (1) ES2284256T3 (de)
WO (1) WO2000001388A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0203371A3 (en) 1999-11-12 2005-02-28 Biogen Idec Ma Inc Cambridge Adenosine receptor antagonists and methods of making and using the same
CN100390178C (zh) 1999-11-12 2008-05-28 拜奥根Idec马萨诸塞公司 作为腺苷受体拮抗剂的多环烷基嘌呤
EP1251130B1 (de) * 1999-12-24 2005-02-16 Kyowa Hakko Kogyo Co., Ltd. Kondensierte purinderivate
CZ20031513A3 (cs) * 2000-12-01 2003-09-17 Biogen, Inc. Kondenzované purinové deriváty jako antagonisty A1 adenosinového receptoru
JP4450628B2 (ja) 2002-03-22 2010-04-14 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ファルネシルトランスフェラーゼインヒビターとして使用するためのベンジルイミダゾリル置換２−キノリンおよびキナゾリン誘導体
WO2003097064A1 (en) * 2002-05-17 2003-11-27 Kyowa Hakko Kogyo Co., Ltd. Therapeutic agent for diabetes
US20070191402A1 (en) * 2002-05-17 2007-08-16 Kyowa Hakko Kogyo Co., Ltd. Method of searching substrate having antidiabetic activity
AU2003252697A1 (en) * 2002-07-26 2004-02-16 Kyowa Hakko Kogyo Co., Ltd. Cell differentiation inductor
JP4571497B2 (ja) * 2002-09-19 2010-10-27 杏林製薬株式会社 アミノアルコール誘導体とその付加塩及び免疫抑制剤
EP1637532A1 (de) * 2003-04-25 2006-03-22 Kyowa Hakko Kogyo Co., Ltd. Kondensiertes pyrimidinderivat
US7781617B2 (en) 2004-07-16 2010-08-24 Kyorin Pharmaceutical Co., Ltd Effective use method of medicaments and method of preventing expression of side effect
EP1806338B1 (de) * 2004-10-12 2016-01-20 Kyorin Pharmaceutical Co., Ltd. Verfahren zur herstellung von 2-amino-2-[2-[4-(3-benzyloxyphenylthio)-2-chlorphenyl[ethyl]-1,3-propandiolhydrochlorid und hydraten davon, und zwischenprodukte in deren herstellung
PL1932522T3 (pl) * 2005-10-07 2012-09-28 Kyorin Seiyaku Kk Środek terapeutyczny do leczenia choroby wątroby zawierający jako składnik czynny pochodną 2-amino-1,3-propanodiolu
TWI389683B (zh) * 2006-02-06 2013-03-21 Kyorin Seiyaku Kk A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient
MX2009000170A (es) 2006-06-23 2009-01-23 Incyte Corp Derivados de purinona como agonistas de hm74a.
ES2355325T3 (es) * 2006-06-23 2011-03-24 Incyte Corporation Derivados de purinona como agonistas de hm74a.
MX2009000169A (es) * 2006-06-23 2009-01-26 Incyte Corp Derivados de purinona como agonistas de hm74a.
JP5140593B2 (ja) * 2006-08-08 2013-02-06 杏林製薬株式会社 アミノアルコール誘導体及びそれらを有効成分とする免疫抑制剤
CA2659598A1 (en) * 2006-08-08 2008-02-14 Kyorin Pharmaceutical Co., Ltd. Amino phosphate derivative and s1p receptor modulator having same as an active ingredient
JP4337898B2 (ja) * 2007-03-29 2009-09-30 セイコーエプソン株式会社 半導体装置
TW200946105A (en) 2008-02-07 2009-11-16 Kyorin Seiyaku Kk Therapeutic agent or preventive agent for inflammatory bowel disease containing amino alcohol derivative as active ingredient
EP2145621A1 (de) * 2008-07-16 2010-01-20 Stephan Lück Verhinderung der Dehydrierung und Reduzierung der gluconeogenetischen Verluste von Aminosäuren durch Propan-1,2,3-Triol
CN103492359B (zh) * 2011-04-02 2015-11-25 中国人民解放军军事医学科学院毒物药物研究所 氨基苯丙醇类化合物及其用于制备免疫抑制剂的用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69033614T2 (de) * 1989-10-20 2001-04-19 Kyowa Hakko Kogyo K.K., Tokio/Tokyo Kondensierte Purinderivate
GB9015914D0 (en) * 1990-07-19 1990-09-05 Wellcome Found Heterocyclic compounds
JP3204880B2 (ja) 1995-07-25 2001-09-04 株式会社バーテックススタンダード デジタルフィルタ
CA2239881A1 (en) * 1996-10-07 1998-04-16 Nobuo Kosaka Condensed purine derivatives
JP4354016B2 (ja) * 1996-11-29 2009-10-28 株式会社メディサイエンスプラニング 新規プリン誘導体およびこれを含む医薬組成物

Also Published As

Publication number Publication date
DE69935718D1 (de) 2007-05-16
CA2336412C (en) 2007-11-27
DE69935718T2 (de) 2007-12-27
AU4396899A (en) 2000-01-24
ES2284256T3 (es) 2007-11-01
EP1092435A4 (de) 2004-03-17
WO2000001388A1 (en) 2000-01-13
EP1092435B1 (de) 2007-04-04
EP1092435A1 (de) 2001-04-18
US6489331B1 (en) 2002-12-03
CA2336412A1 (en) 2000-01-13

Similar Documents

Publication Publication Date Title
ATE358484T1 (de) Antidiabetische medikamente
NO20020968L (no) Glukopyranosyloksypyrazolderivater, medisinske sammensetninger inneholdende det samme og intermediater forfremstillingen derav
EP1043317A4 (de) Pyridazinderivate und dieselben als aktive bestandteile enthaltende medikamente
PT976748E (pt) Derivados de pirrolidina com actividade inibidora de fosfolipase a2
ES2096073T3 (es) Derivado de benzamida.
EA200100916A1 (ru) Лекарственное средство, содержащее производное сульфопиранозилацилглицерина
DK0882728T3 (da) 1-methylcarbapenemderivater
DE69814800D1 (de) Epoxysuccinamid-derivate oder ihre salze
IL150965A0 (en) Therapeutic or preventive agent for digestive system diseases containing a diaminotrifluoromethylpyridine derivative
AU2318600A (en) Chondrongenesis promotors and indolin-2-one derivatives
HK95092A (en) 2-substituted n,n-di-trimethoxybenzoyl piperazines and pharmaceutical uses thereof
IL169577A0 (en) Oligosaccharide derivatives and pharmaceutical compostions containing the same
DE60238847D1 (de) Pyrimidinderivate enthaltendes medikament
DE69729890D1 (de) Heilmittel/vorbeugemittel für erkrankungen der atemwege
DE69722630D1 (de) Therapeutisches mittel zur behandlung von nierenerkrankungen

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties