ATE358675T1 - Stabiles lansoprazol, enthaltend mehr als 500 ppm bis zu 3000 ppm wasser und mehr als 200 ppm bis zu 5000 ppm alkohol - Google Patents

Stabiles lansoprazol, enthaltend mehr als 500 ppm bis zu 3000 ppm wasser und mehr als 200 ppm bis zu 5000 ppm alkohol

Info

Publication number
ATE358675T1
ATE358675T1 AT03789888T AT03789888T ATE358675T1 AT E358675 T1 ATE358675 T1 AT E358675T1 AT 03789888 T AT03789888 T AT 03789888T AT 03789888 T AT03789888 T AT 03789888T AT E358675 T1 ATE358675 T1 AT E358675T1
Authority
AT
Austria
Prior art keywords
ppm
alcohol
water
stable
present
Prior art date
Application number
AT03789888T
Other languages
English (en)
Inventor
Claude Singer
Anita Liberman
Irena Veinberg
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Application granted granted Critical
Publication of ATE358675T1 publication Critical patent/ATE358675T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT03789888T 2002-11-18 2003-11-18 Stabiles lansoprazol, enthaltend mehr als 500 ppm bis zu 3000 ppm wasser und mehr als 200 ppm bis zu 5000 ppm alkohol ATE358675T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42758902P 2002-11-18 2002-11-18
US44521903P 2003-02-05 2003-02-05

Publications (1)

Publication Number Publication Date
ATE358675T1 true ATE358675T1 (de) 2007-04-15

Family

ID=32329173

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03789888T ATE358675T1 (de) 2002-11-18 2003-11-18 Stabiles lansoprazol, enthaltend mehr als 500 ppm bis zu 3000 ppm wasser und mehr als 200 ppm bis zu 5000 ppm alkohol

Country Status (10)

Country Link
US (1) US7683080B2 (de)
EP (1) EP1465890B1 (de)
JP (2) JP2005527638A (de)
KR (1) KR20050075424A (de)
AT (1) ATE358675T1 (de)
AU (1) AU2003294405A1 (de)
DE (2) DE60312953T2 (de)
ES (1) ES2237354T3 (de)
PT (1) PT1465890E (de)
WO (1) WO2004046135A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2237354T3 (es) * 2002-11-18 2007-11-01 Teva Pharmaceutical Industries Ltd. Lansoprazol estable que contiene mas de 500 ppm, hasta aproximadamente 3.000 ppm de agua y mas de 200 ppm, hasta aproximadamente 5.000 ppm de alcohol.
JP2006516574A (ja) * 2003-02-05 2006-07-06 テバ ファーマシューティカル インダストリーズ リミティド ランソプラゾール安定化方法
JP5173191B2 (ja) * 2004-09-13 2013-03-27 武田薬品工業株式会社 酸化化合物の製造方法及び製造装置
WO2006068105A1 (ja) * 2004-12-20 2006-06-29 Santen Pharmaceutical Co., Ltd. 角結膜障害治療剤
CN1919844B (zh) * 2006-09-01 2010-05-12 武汉工程大学 水相氧化合成兰索拉唑的方法
CN109265442A (zh) * 2018-10-12 2019-01-25 河南精康制药有限公司 一种原料药兰索拉唑的精制方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6150978A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
DE3529529A1 (de) 1985-08-17 1987-02-19 Boehringer Mannheim Gmbh Verfahren zur herstellung einer stabilen modifikation von torasemid
DK171989B1 (da) 1987-08-04 1997-09-08 Takeda Chemical Industries Ltd Fremgangsmåde til fremstilling af 2-(2-pyridylmethylsulfinyl)-benzimidazoler
ES2036948B1 (es) 1991-11-21 1994-09-01 Genesis Para La Investigacion Procedimiento de obtencion de compuestos derivados de piridina.
TW385306B (en) * 1996-11-14 2000-03-21 Takeda Chemical Industries Ltd Method for producing crystals of benzimidazole derivatives
WO1999002521A1 (en) 1997-07-11 1999-01-21 Eisai Co., Ltd. Processes for the preparation of pyridine derivatives
GB9805558D0 (en) 1998-03-17 1998-05-13 Knoll Ag Chemical process`
SI20019A (sl) 1998-07-13 2000-02-29 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Izboljšan postopek sinteze 5-metoksi -2-/(4-metoksi-3,5-dimetil-2-piridil)metil/ sulfinil-1H-benzimidazola
JP3926936B2 (ja) 1998-11-16 2007-06-06 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホキシド誘導体・アセトン錯体およびその製造法
KR100362947B1 (ko) * 1999-09-21 2002-11-30 주식회사 대웅 설폭시드 화합물의 제조방법
ES2163372B1 (es) 2000-03-13 2003-05-01 Esteve Quimica Sa Procedimiento de oxidacion de un grupo tioeter a sulfoxido.
JP2002002230A (ja) 2000-06-15 2002-01-08 Ohtsu Tire & Rubber Co Ltd :The 農用車輪
JP4019244B2 (ja) 2000-09-18 2007-12-12 三菱マテリアル株式会社 耐チッピング性のすぐれた表面被覆超硬合金製切削工具
SK10792003A3 (sk) * 2001-02-02 2004-07-07 Teva Pharmaceutical Industries Ltd. Spôsob výroby substituovaných 2-(2-pyridylmetyl) sulfinyl -1H-benzimidazolov
US20030138466A1 (en) * 2001-11-28 2003-07-24 Bradley Pharmaceuticals, Inc. Antioxidant dermatological composition
ATE375338T1 (de) 2002-08-21 2007-10-15 Teva Pharma Verfahren zur aufreinigung von lanzoprazol
ES2237354T3 (es) * 2002-11-18 2007-11-01 Teva Pharmaceutical Industries Ltd. Lansoprazol estable que contiene mas de 500 ppm, hasta aproximadamente 3.000 ppm de agua y mas de 200 ppm, hasta aproximadamente 5.000 ppm de alcohol.

Also Published As

Publication number Publication date
JP2005527638A (ja) 2005-09-15
JP2007051165A (ja) 2007-03-01
EP1465890A1 (de) 2004-10-13
US20040215021A1 (en) 2004-10-28
DE60312953T2 (de) 2007-12-13
AU2003294405A1 (en) 2004-06-15
KR20050075424A (ko) 2005-07-20
EP1465890B1 (de) 2007-04-04
WO2004046135A1 (en) 2004-06-03
PT1465890E (pt) 2007-05-31
DE60312953D1 (de) 2007-05-16
ES2237354T3 (es) 2007-11-01
US7683080B2 (en) 2010-03-23
ES2237354T1 (es) 2005-08-01
DE03789888T1 (de) 2005-08-18

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