ATE359369T1 - Rns-abhängige rns-polymerase, die vorzugsweise anhand einer rna-matrix funktioniert und ein promoter-abhängiger transkriptionsprozess , der diese rns-abhängige rns-polymerase benutzt. - Google Patents

Rns-abhängige rns-polymerase, die vorzugsweise anhand einer rna-matrix funktioniert und ein promoter-abhängiger transkriptionsprozess , der diese rns-abhängige rns-polymerase benutzt.

Info

Publication number
ATE359369T1
ATE359369T1 AT98917263T AT98917263T ATE359369T1 AT E359369 T1 ATE359369 T1 AT E359369T1 AT 98917263 T AT98917263 T AT 98917263T AT 98917263 T AT98917263 T AT 98917263T AT E359369 T1 ATE359369 T1 AT E359369T1
Authority
AT
Austria
Prior art keywords
rna
dependent
rna polymerase
matrix
polymerase
Prior art date
Application number
AT98917263T
Other languages
English (en)
Inventor
Valerie Cheynet-Sauvion
Nadege Arnaud-Barbe
Guy Oriol
William Mcallister
Bernard Mandrand
Francois Mallet
Original Assignee
Bio Merieux
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Merieux filed Critical Bio Merieux
Application granted granted Critical
Publication of ATE359369T1 publication Critical patent/ATE359369T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/127—RNA-directed RNA polymerase (2.7.7.48), i.e. RNA replicase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT98917263T 1997-04-04 1998-03-27 Rns-abhängige rns-polymerase, die vorzugsweise anhand einer rna-matrix funktioniert und ein promoter-abhängiger transkriptionsprozess , der diese rns-abhängige rns-polymerase benutzt. ATE359369T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9704166A FR2761695B1 (fr) 1997-04-04 1997-04-04 Arn polymerase fonctionnant preferentiellement sur matrice d'arn, sa preparation et son utilisation

Publications (1)

Publication Number Publication Date
ATE359369T1 true ATE359369T1 (de) 2007-05-15

Family

ID=9505551

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98917263T ATE359369T1 (de) 1997-04-04 1998-03-27 Rns-abhängige rns-polymerase, die vorzugsweise anhand einer rna-matrix funktioniert und ein promoter-abhängiger transkriptionsprozess , der diese rns-abhängige rns-polymerase benutzt.

Country Status (10)

Country Link
US (2) US6828127B2 (de)
EP (1) EP0972051B1 (de)
JP (1) JP4004072B2 (de)
AT (1) ATE359369T1 (de)
AU (1) AU7052898A (de)
CA (1) CA2286343C (de)
DE (1) DE69837535T2 (de)
ES (1) ES2285766T3 (de)
FR (1) FR2761695B1 (de)
WO (1) WO1998045449A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1261696B1 (de) * 2000-03-07 2005-05-04 bioMerieux B.V. Rna polymerase mutanten mit erhöhter thermostabilität
US7074558B2 (en) * 2001-06-07 2006-07-11 Pbi Technology, Inc. Nucleic acid amplification using an RNA polymerase and DNA/RNA mixed polymer intermediate products
FR2828509B1 (fr) 2001-08-08 2003-11-21 D Lascaud Ets Panneau isolant thermique
WO2006071776A2 (en) * 2004-12-23 2006-07-06 Ge Healthcare Bio-Sciences Corp. Ligation-based rna amplification
CN107460177B (zh) * 2016-06-06 2021-08-17 张海生 可利用化学修饰核苷酸的rna聚合酶突变体
JP7613833B2 (ja) * 2017-03-28 2025-01-15 味の素株式会社 Ｒｎａの製造方法
JP2023517540A (ja) * 2020-03-03 2023-04-26 ロケットヴァックス アーゲー コロナウイルスに対して保護するためのワクチン産生のための完全合成長鎖核酸
CN115505589B (zh) * 2021-07-27 2025-07-25 上海兆维科技发展有限公司 一种rna的制备方法、合成蛋白质的方法以及转录反应液

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE659881C (de) 1936-04-25 1938-05-14 I G Farbenindustrie Akt Ges Verfahren zur Herstellung von Dehydrobinaphthylendiimin und seinen Substitutionsprodukten
DE68926460T2 (de) * 1988-12-05 1996-09-12 Salk Inst For Biological Studi Systeme für amplifikation/nachweis von nukleinsäuren
US5122457A (en) 1989-10-19 1992-06-16 Schering Corporation Expression systems utilizing bacteriophage t7 promoters, gene sequences, and t7 rna polymerase
FR2708288B1 (fr) 1993-07-26 1995-09-01 Bio Merieux Procédé d'amplification d'acides nucléiques par transcription utilisant le déplacement, réactifs et nécessaire pour la mise en Óoeuvre de ce procédé.
FR2714062B1 (fr) * 1993-12-22 1996-02-16 Bio Merieux Promoteur modifié pour ARN polymérase, sa préparation et ses applications.
CA2223241C (en) * 1995-06-07 2009-11-17 Gen-Probe Incorporated Methods and kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
ATE318896T1 (de) * 1995-09-27 2006-03-15 Univ Emory Rekombinante rna-replikase von hepatitis-c-virus

Also Published As

Publication number Publication date
US20020119449A1 (en) 2002-08-29
FR2761695B1 (fr) 1999-09-24
ES2285766T3 (es) 2007-11-16
CA2286343C (fr) 2008-12-23
EP0972051B1 (de) 2007-04-11
AU7052898A (en) 1998-10-30
US20050069933A1 (en) 2005-03-31
FR2761695A1 (fr) 1998-10-09
US6828127B2 (en) 2004-12-07
WO1998045449A1 (fr) 1998-10-15
EP0972051A1 (de) 2000-01-19
DE69837535T2 (de) 2007-12-13
JP2001507942A (ja) 2001-06-19
CA2286343A1 (fr) 1998-10-15
DE69837535D1 (de) 2007-05-24
JP4004072B2 (ja) 2007-11-07
US7595180B2 (en) 2009-09-29

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