ATE359832T1 - Verfahren und vorrichtung zum herstellung von kontrastmitteln für magnetresonanzbildgebung - Google Patents

Verfahren und vorrichtung zum herstellung von kontrastmitteln für magnetresonanzbildgebung

Info

Publication number
ATE359832T1
ATE359832T1 AT03790942T AT03790942T ATE359832T1 AT E359832 T1 ATE359832 T1 AT E359832T1 AT 03790942 T AT03790942 T AT 03790942T AT 03790942 T AT03790942 T AT 03790942T AT E359832 T1 ATE359832 T1 AT E359832T1
Authority
AT
Austria
Prior art keywords
contrast agent
sub
magnetic field
magnetic resonance
resonance imaging
Prior art date
Application number
AT03790942T
Other languages
English (en)
Inventor
Ardenkjaer-Larsen
Oskar Axelsson
Maurice Goldman
Haukur Johanesson
Original Assignee
Ge Healthcare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare As filed Critical Ge Healthcare As
Application granted granted Critical
Publication of ATE359832T1 publication Critical patent/ATE359832T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/445—MR involving a non-standard magnetic field B0, e.g. of low magnitude as in the earth's magnetic field or in nanoTesla spectroscopy, comprising a polarizing magnetic field for pre-polarisation, B0 with a temporal variation of its magnitude or direction such as field cycling of B0 or rotation of the direction of B0, or spatially inhomogeneous B0 like in fringe-field MR or in stray-field imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5605—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by transferring coherence or polarization from a spin species to another, e.g. creating magnetization transfer contrast [MTC], polarization transfer using nuclear Overhauser enhancement [NOE]

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Signal Processing (AREA)
  • Epidemiology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
AT03790942T 2002-08-29 2003-08-29 Verfahren und vorrichtung zum herstellung von kontrastmitteln für magnetresonanzbildgebung ATE359832T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0219953.7A GB0219953D0 (en) 2002-08-29 2002-08-29 An arrangement and a method for providing contrast agents

Publications (1)

Publication Number Publication Date
ATE359832T1 true ATE359832T1 (de) 2007-05-15

Family

ID=9943071

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03790942T ATE359832T1 (de) 2002-08-29 2003-08-29 Verfahren und vorrichtung zum herstellung von kontrastmitteln für magnetresonanzbildgebung

Country Status (9)

Country Link
US (1) US20060127314A1 (de)
EP (1) EP1562639B1 (de)
JP (1) JP4437280B2 (de)
CN (1) CN100418584C (de)
AT (1) ATE359832T1 (de)
AU (1) AU2003266325A1 (de)
DE (1) DE60313354T2 (de)
GB (1) GB0219953D0 (de)
WO (1) WO2004019996A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008086534A1 (en) 2007-01-11 2008-07-17 Huntington Medical Research Institutes Imaging agents and methods of use thereof
WO2009111876A1 (en) 2008-03-11 2009-09-17 The University Of Western Ontario System and method for magnetic resonance imaging
WO2009129265A1 (en) 2008-04-14 2009-10-22 Huntington Medical Research Institutes Methods and apparatus for pasadena hyperpolarization
US9423480B2 (en) 2008-10-27 2016-08-23 The University Of Western Ontario System and method for magnetic resonance imaging
WO2012145733A1 (en) 2011-04-22 2012-10-26 Vanderbilt University Para-hydrogen polarizer
US9329246B2 (en) 2012-10-03 2016-05-03 Bruker Biospin Ag Method for hyperpolarization transfer in the liquid state
CN103432977B (zh) * 2013-08-29 2015-01-07 中国科学院武汉物理与数学研究所 一种用于磁共振造影剂预极化的级联容器及其方法
WO2017009856A1 (en) * 2015-07-16 2017-01-19 Aspect Imaging Ltd. Method and system for hyperpolarization of materials used in magnetic resonance imaging
CA3033346A1 (en) * 2016-08-09 2018-02-15 Beth Israel Deaconess Medical Center, Inc. System and method for microfluidic parahydrogen induced polarization hyperpolarizer for magnetic resonance imaging (mri) and nuclear magnetic resonance (nmr) applications
DE102018119695A1 (de) * 2018-08-14 2020-02-20 Albert-Ludwigs-Universität Freiburg Verfahren und Vorrichtung zur Hydrierung und Hyperpolarisierung von Tracer-Molekülen für die Magnetresonanzbildgebung
US11887763B2 (en) * 2019-01-02 2024-01-30 Northrop Grumman Systems Corporation Degaussing a magnetized structure
EP4012433A4 (de) * 2019-08-06 2023-08-30 National University Corporation Hokkaido University Polarisationsübertragungsvorrichtung und mikrofluidische vorrichtung
DE102023133847A1 (de) * 2023-12-04 2025-06-05 Albert-Ludwigs-Universität Freiburg, Körperschaft des öffentlichen Rechts Hyperpolarisator, Hyperpolarisationsanordnung, Verfahren zur Hyperpolarisierung und Verfahren zur Herstellung eines Kontrastmittels

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1269015A (zh) * 1997-06-19 2000-10-04 耐克麦德英梅金公司 使用体外极化磁共振成像剂的奥氏磁共振成像方法
KR100600670B1 (ko) * 1997-11-12 2006-07-13 지이 헬스케어 에이에스 파라수소 표지된 작용물질 및 자기공명영상에서의 그의 용도
US7501236B1 (en) * 1998-12-30 2009-03-10 Ge Healthcare Limited NMR spectroscopic in vitro assay using hyperpolarization
GB9911681D0 (en) * 1999-05-19 1999-07-21 Nycomed Imaging As Process

Also Published As

Publication number Publication date
EP1562639A1 (de) 2005-08-17
US20060127314A1 (en) 2006-06-15
CN1694729A (zh) 2005-11-09
DE60313354D1 (de) 2007-05-31
JP4437280B2 (ja) 2010-03-24
CN100418584C (zh) 2008-09-17
DE60313354T2 (de) 2008-01-03
JP2005536305A (ja) 2005-12-02
GB0219953D0 (en) 2002-10-02
WO2004019996A1 (en) 2004-03-11
EP1562639B1 (de) 2007-04-18
AU2003266325A1 (en) 2004-03-19

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