ATE335514T1 - Verfahren und vorrichtung zur herstellung von kontrastmitteln für magnetresonanzbildgebung - Google Patents

Verfahren und vorrichtung zur herstellung von kontrastmitteln für magnetresonanzbildgebung

Info

Publication number
ATE335514T1
ATE335514T1 AT03790941T AT03790941T ATE335514T1 AT E335514 T1 ATE335514 T1 AT E335514T1 AT 03790941 T AT03790941 T AT 03790941T AT 03790941 T AT03790941 T AT 03790941T AT E335514 T1 ATE335514 T1 AT E335514T1
Authority
AT
Austria
Prior art keywords
sub
magnetic resonance
resonance imaging
contrast agent
magnetic field
Prior art date
Application number
AT03790941T
Other languages
English (en)
Inventor
Maurice Goldman
Oskar Axelsson
Haukur Johannesson
J Ardenkjaer-Larsen
Original Assignee
Ge Healthcare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare As filed Critical Ge Healthcare As
Application granted granted Critical
Publication of ATE335514T1 publication Critical patent/ATE335514T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/282—Means specially adapted for hyperpolarisation or for hyperpolarised contrast agents, e.g. for the generation of hyperpolarised gases using optical pumping cells, for storing hyperpolarised contrast agents or for the determination of the polarisation of a hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT03790941T 2002-08-29 2003-08-29 Verfahren und vorrichtung zur herstellung von kontrastmitteln für magnetresonanzbildgebung ATE335514T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0219954.5A GB0219954D0 (en) 2002-08-29 2002-08-29 Method and apparatus for producing contrast agents for magnetic resonance imaging

Publications (1)

Publication Number Publication Date
ATE335514T1 true ATE335514T1 (de) 2006-09-15

Family

ID=9943072

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03790941T ATE335514T1 (de) 2002-08-29 2003-08-29 Verfahren und vorrichtung zur herstellung von kontrastmitteln für magnetresonanzbildgebung

Country Status (9)

Country Link
US (1) US20060127313A1 (de)
EP (1) EP1531871B1 (de)
JP (1) JP2006510585A (de)
CN (1) CN100335139C (de)
AT (1) ATE335514T1 (de)
AU (1) AU2003258687A1 (de)
DE (1) DE60307477T2 (de)
GB (1) GB0219954D0 (de)
WO (1) WO2004019995A2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007044867A2 (en) * 2005-10-11 2007-04-19 Huntington Medical Research Institutes Imaging agents and methods of use thereof
WO2008086534A1 (en) 2007-01-11 2008-07-17 Huntington Medical Research Institutes Imaging agents and methods of use thereof
GB2450316A (en) * 2007-06-18 2008-12-24 Univ York Hyperpolarizing nuclei
US20100233089A1 (en) * 2007-10-05 2010-09-16 Huntington Medical Research Institutes Imaging of genetic material with magnetic resonance
WO2009129265A1 (en) * 2008-04-14 2009-10-22 Huntington Medical Research Institutes Methods and apparatus for pasadena hyperpolarization
EP2374016B1 (de) 2008-12-10 2017-05-10 University of York Impulssequenzierung mit hyperpolarisierbaren kernen
WO2012145733A1 (en) * 2011-04-22 2012-10-26 Vanderbilt University Para-hydrogen polarizer
US9329246B2 (en) 2012-10-03 2016-05-03 Bruker Biospin Ag Method for hyperpolarization transfer in the liquid state
CN103837561A (zh) * 2014-03-11 2014-06-04 吴仁华 一种双量子滤波技术检测脑内γ-氨基丁酸的方法
KR102346071B1 (ko) * 2014-03-14 2021-12-31 더 제너럴 하스피탈 코포레이션 로우-필드, 다중-채널 이미징을 위한 시스템 및 방법
CN103941205B (zh) * 2014-05-06 2016-09-14 厦门大学 一种不均匀场下改善核磁共振氢谱分辨率的方法
US9702946B1 (en) * 2014-05-12 2017-07-11 Konstantin Saprygin Creation of long-lived singlet states of gases and their use as inhalable MRI contrast agents
HK1252007A1 (zh) * 2015-05-12 2019-05-10 Hyperfine, Inc. 射频线圈方法和装置
CA3033346A1 (en) * 2016-08-09 2018-02-15 Beth Israel Deaconess Medical Center, Inc. System and method for microfluidic parahydrogen induced polarization hyperpolarizer for magnetic resonance imaging (mri) and nuclear magnetic resonance (nmr) applications
WO2018081626A1 (en) * 2016-10-28 2018-05-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Stable water isotope labeling and magnetic resonance imaging for visualization of rapidly dividing cells
CN108107391B (zh) * 2017-12-18 2019-08-13 厦门大学 一种单体素定域一维高分辨同核去耦谱方法
JP7408351B2 (ja) * 2019-11-06 2024-01-05 キヤノンメディカルシステムズ株式会社 磁気共鳴イメージング装置
DE102020200013A1 (de) * 2020-01-03 2021-07-08 Siemens Healthcare Gmbh Magnetresonanzeinrichtung und Verfahren zum Betrieb einer Magnetresonanzeinrichtung, Computerprogramm und elektronisch lesbarer Datenträger
JP7846128B2 (ja) * 2020-12-07 2026-04-14 エヌビジョン イメージング テクノロジーズ ゲゼルシャフト ミット ベシュレンクテル ハフツング パラ水素を使用する超偏極化合物の生成のためのシステム及び方法
US20250283959A1 (en) * 2022-04-23 2025-09-11 Wayne State University Method and apparatus for magnetic resonance (mr) contrast agents

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US4543529A (en) * 1983-01-04 1985-09-24 Nmr Imaging, Inc. Method of tuning an NMR apparatus
US5432446A (en) * 1992-11-02 1995-07-11 Schlumberger Technology Corporation Borehole measurement of NMR characteristics of earth formation
US6311093B1 (en) * 1997-06-20 2001-10-30 Peter G. Brown System and method for simulation, modeling and scheduling of equipment maintenance and calibration in biopharmaceutical batch process manufacturing facilities
EP1050001A4 (de) * 1997-06-20 2000-12-06 Peter G Brown System und verfahren zur simulation, modellierung und zeitplanung von prozessunterstützungsoperationen in diskontinuierlichen biopharmazeutischen herstellungsanlagen
KR100600670B1 (ko) * 1997-11-12 2006-07-13 지이 헬스케어 에이에스 파라수소 표지된 작용물질 및 자기공명영상에서의 그의 용도
US6278893B1 (en) * 1998-01-05 2001-08-21 Nycomed Imaging As Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent
GB9911681D0 (en) * 1999-05-19 1999-07-21 Nycomed Imaging As Process

Also Published As

Publication number Publication date
AU2003258687A8 (en) 2004-03-19
EP1531871A2 (de) 2005-05-25
WO2004019995A2 (en) 2004-03-11
US20060127313A1 (en) 2006-06-15
DE60307477D1 (de) 2006-09-21
AU2003258687A1 (en) 2004-03-19
CN100335139C (zh) 2007-09-05
WO2004019995A3 (en) 2004-05-13
DE60307477T2 (de) 2007-03-29
CN1694730A (zh) 2005-11-09
JP2006510585A (ja) 2006-03-30
GB0219954D0 (en) 2002-10-02
EP1531871B1 (de) 2006-08-09

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