ATE361319T1 - Herstellungsverfahren von lactalbumin - Google Patents
Herstellungsverfahren von lactalbuminInfo
- Publication number
- ATE361319T1 ATE361319T1 AT98955823T AT98955823T ATE361319T1 AT E361319 T1 ATE361319 T1 AT E361319T1 AT 98955823 T AT98955823 T AT 98955823T AT 98955823 T AT98955823 T AT 98955823T AT E361319 T1 ATE361319 T1 AT E361319T1
- Authority
- AT
- Austria
- Prior art keywords
- lactalbumin
- alpha
- oligomeric form
- ion exchange
- exchange medium
- Prior art date
Links
- 102000004407 Lactalbumin Human genes 0.000 title abstract 7
- 108090000942 Lactalbumin Proteins 0.000 title abstract 7
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 235000021241 α-lactalbumin Nutrition 0.000 abstract 6
- 239000005018 casein Substances 0.000 abstract 2
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 abstract 2
- 235000021240 caseins Nutrition 0.000 abstract 2
- 238000005342 ion exchange Methods 0.000 abstract 2
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 abstract 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 abstract 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 abstract 1
- 101000946377 Bos taurus Alpha-lactalbumin Proteins 0.000 abstract 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000005642 Oleic acid Substances 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 235000020256 human milk Nutrition 0.000 abstract 1
- 210000004251 human milk Anatomy 0.000 abstract 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 abstract 1
- 238000002203 pretreatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9724725.8A GB9724725D0 (en) | 1997-11-21 | 1997-11-21 | Protein production process |
| GBGB9812202.1A GB9812202D0 (en) | 1997-11-21 | 1998-06-05 | Protein production process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE361319T1 true ATE361319T1 (de) | 2007-05-15 |
Family
ID=26312643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98955823T ATE361319T1 (de) | 1997-11-21 | 1998-11-23 | Herstellungsverfahren von lactalbumin |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7053185B1 (de) |
| EP (1) | EP1032596B1 (de) |
| JP (1) | JP2001524491A (de) |
| AT (1) | ATE361319T1 (de) |
| AU (1) | AU1254199A (de) |
| DE (1) | DE69837719T2 (de) |
| DK (1) | DK1032596T3 (de) |
| ES (1) | ES2286860T3 (de) |
| WO (1) | WO1999026979A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2373166C (en) * | 1999-07-28 | 2009-05-19 | Morinaga Milk Industry Co., Ltd. | Antiulcer agent |
| US20030077255A1 (en) * | 2001-04-16 | 2003-04-24 | Sabharwal Hemant K. | Compositions of bacteria and alpha-lactalbumin and uses thereof |
| GB0205347D0 (en) * | 2002-03-07 | 2002-04-24 | Svanborg Catharina | Biologically active complex |
| GB0210464D0 (en) | 2002-05-08 | 2002-06-12 | Svanborg Catharina | Therapeutic treatment |
| WO2007088869A1 (ja) * | 2006-02-01 | 2007-08-09 | National University Corporation Hokkaido University | ラクトアルブミン変性物の製造方法 |
| WO2008138348A1 (en) * | 2007-05-09 | 2008-11-20 | Nya Hamlet Pharma Ab | Preparation of complexed lactalbumin |
| DK2385954T3 (da) | 2009-01-09 | 2013-06-17 | Hamlet Pharma Ab | Kompleks og fremstillingsproces |
| DK2643010T3 (en) * | 2010-11-24 | 2017-02-27 | Hamlet Pharma Ab | BIOLOGICAL ACTIVE COMPLEX AND ITS PREPARATION |
| JP6223444B2 (ja) | 2012-07-05 | 2017-11-01 | ザ リサーチ ファウンデイション フォー ザ ステイト ユニバーシティー オブ ニューヨーク | 蛋白質‐脂質複合体を用いた抗生物質治療の増強 |
| EP3295953B1 (de) * | 2012-08-09 | 2020-10-21 | HAMLET Pharma AB | Milchprotein - fettsäure komplex |
| CN104399065A (zh) * | 2014-10-17 | 2015-03-11 | 广东海洋大学 | 一种可诱导人乳腺癌细胞凋亡的牛乳蛋白脂肪酸修饰物及其制备方法 |
| EP3815763A1 (de) * | 2019-11-01 | 2021-05-05 | I3 Membrane GmbH | Verfahren und vorrichtung zur gleichspannungsgesteuerten adsorption und desorption an geladenen membranen |
| AU2023357946A1 (en) | 2022-10-03 | 2025-04-24 | Linnane Pharma Ab | A complex comprising a alpha-lactalbumin and a fatty acid or lipid for use in the treatment or prevention of cancer |
| GB202303177D0 (en) | 2023-03-03 | 2023-04-19 | Linnane Pharma Ab | Method of predicting response to treatment |
| WO2025186107A1 (en) | 2024-03-04 | 2025-09-12 | Linnane Pharma Ab | Therapy |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2961625B2 (ja) | 1991-01-21 | 1999-10-12 | 雪印乳業株式会社 | α−ラクトアルブミン含有量の高い組成物の製造方法 |
| AU7792294A (en) * | 1994-08-16 | 1996-03-07 | Hemant Sabharwal | Antibacterial composition containing multimeric alpha-lactalbumin |
-
1998
- 1998-11-23 DE DE69837719T patent/DE69837719T2/de not_active Expired - Lifetime
- 1998-11-23 AU AU12541/99A patent/AU1254199A/en not_active Abandoned
- 1998-11-23 AT AT98955823T patent/ATE361319T1/de not_active IP Right Cessation
- 1998-11-23 ES ES98955823T patent/ES2286860T3/es not_active Expired - Lifetime
- 1998-11-23 EP EP98955823A patent/EP1032596B1/de not_active Expired - Lifetime
- 1998-11-23 WO PCT/IB1998/001919 patent/WO1999026979A1/en not_active Ceased
- 1998-11-23 US US09/554,704 patent/US7053185B1/en not_active Expired - Fee Related
- 1998-11-23 JP JP2000522135A patent/JP2001524491A/ja active Pending
- 1998-11-23 DK DK98955823T patent/DK1032596T3/da active
-
2006
- 2006-01-27 US US11/275,760 patent/US7524932B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DK1032596T3 (da) | 2007-09-10 |
| US7524932B2 (en) | 2009-04-28 |
| US20060229436A1 (en) | 2006-10-12 |
| ES2286860T3 (es) | 2007-12-01 |
| DE69837719T2 (de) | 2008-01-31 |
| EP1032596B1 (de) | 2007-05-02 |
| WO1999026979A1 (en) | 1999-06-03 |
| EP1032596A1 (de) | 2000-09-06 |
| AU1254199A (en) | 1999-06-15 |
| JP2001524491A (ja) | 2001-12-04 |
| US7053185B1 (en) | 2006-05-30 |
| DE69837719D1 (de) | 2007-06-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1032596 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |