ATE361748T1 - 1-(4-sulfamylphenyl)-3-trifluormethyl-5-aryl-2- pyrazoline als cyclooxygenase-2 inhibitoren - Google Patents

1-(4-sulfamylphenyl)-3-trifluormethyl-5-aryl-2- pyrazoline als cyclooxygenase-2 inhibitoren

Info

Publication number: ATE361748T1
Authority: AT; Austria
Prior art keywords: sub; cyclooxygenase; group; inhibitors; aryl
Prior art date: 1999-06-16

Application number

AT00939946T

Other languages

English (en)

Inventor

E Reddy

M Reddy

Original Assignee

Univ Temple

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-16

Filing date

2000-06-16

Publication date

2007-06-15

2000-06-16 Application filed by Univ Temple filed Critical Univ Temple

2007-06-15 Application granted granted Critical

2007-06-15 Publication of ATE361748T1 publication Critical patent/ATE361748T1/de

Links

239000003255 cyclooxygenase 2 inhibitor Substances 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
230000001404 mediated effect Effects 0.000 abstract 2
102000010907 Cyclooxygenase 2 Human genes 0.000 abstract 1
108010037462 Cyclooxygenase 2 Proteins 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
102000004005 Prostaglandin-endoperoxide synthases Human genes 0.000 abstract 1
108090000459 Prostaglandin-endoperoxide synthases Proteins 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
230000033115 angiogenesis Effects 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
230000001613 neoplastic effect Effects 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000004385 trihaloalkyl group Chemical group 0.000 abstract 1
125000004953 trihalomethyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
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Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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AT00939946T 1999-06-16 2000-06-16 1-(4-sulfamylphenyl)-3-trifluormethyl-5-aryl-2- pyrazoline als cyclooxygenase-2 inhibitoren ATE361748T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US13941699P	1999-06-16	1999-06-16

Publications (1)

Publication Number	Publication Date
ATE361748T1 true ATE361748T1 (de)	2007-06-15

Family

ID=22486543

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00939946T ATE361748T1 (de)	1999-06-16	2000-06-16	1-(4-sulfamylphenyl)-3-trifluormethyl-5-aryl-2- pyrazoline als cyclooxygenase-2 inhibitoren

Country Status (11)

Country	Link
US (2)	US6376519B1 (de)
EP (1)	EP1191931B1 (de)
JP (1)	JP2003501464A (de)
KR (1)	KR100796851B1 (de)
AT (1)	ATE361748T1 (de)
AU (1)	AU771668C (de)
CA (1)	CA2377153A1 (de)
DE (1)	DE60034785D1 (de)
IL (2)	IL146851A0 (de)
NZ (1)	NZ516553A (de)
WO (1)	WO2000076503A1 (de)

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2000
- 2000-06-16 KR KR1020017016170A patent/KR100796851B1/ko not_active Expired - Fee Related
- 2000-06-16 WO PCT/US2000/016656 patent/WO2000076503A1/en not_active Ceased
- 2000-06-16 IL IL14685100A patent/IL146851A0/xx active IP Right Grant
- 2000-06-16 AT AT00939946T patent/ATE361748T1/de not_active IP Right Cessation
- 2000-06-16 JP JP2001502836A patent/JP2003501464A/ja active Pending
- 2000-06-16 CA CA002377153A patent/CA2377153A1/en not_active Abandoned
- 2000-06-16 US US09/595,760 patent/US6376519B1/en not_active Ceased
- 2000-06-16 AU AU54951/00A patent/AU771668C/en not_active Ceased
- 2000-06-16 DE DE60034785T patent/DE60034785D1/de not_active Expired - Lifetime
- 2000-06-16 EP EP00939946A patent/EP1191931B1/de not_active Expired - Lifetime
- 2000-06-16 NZ NZ516553A patent/NZ516553A/xx not_active IP Right Cessation
2001
- 2001-11-30 IL IL146851A patent/IL146851A/en not_active IP Right Cessation
2003
- 2003-07-29 US US10/630,397 patent/USRE39681E1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AU771668B2 (en)	2004-04-01
JP2003501464A (ja)	2003-01-14
DE60034785D1 (en)	2007-06-21
USRE39681E1 (en)	2007-06-05
AU5495100A (en)	2001-01-02
EP1191931B1 (de)	2007-05-09
AU771668C (en)	2005-08-11
CA2377153A1 (en)	2000-12-21
IL146851A0 (en)	2002-07-25
IL146851A (en)	2008-03-20
NZ516553A (en)	2004-01-30
US6376519B1 (en)	2002-04-23
KR20020015350A (ko)	2002-02-27
EP1191931A1 (de)	2002-04-03
EP1191931A4 (de)	2002-11-27
WO2000076503A1 (en)	2000-12-21
KR100796851B1 (ko)	2008-01-22

Legal Events

Date	Code	Title	Description
2007-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE60034785D1 (en)	2007-06-21	1-(4-sulfamylphenyl)-3-trifluormethyl-5-aryl-2-pyrazoline als cyclooxygenase-2 inhibitoren
EP1527049B8 (de)	2008-10-29	Kondensierte heterozyklische verbindungen als petidase inhibitoren
ATE180468T1 (de)	1999-06-15	Anthranilsäure derivate
DE60001623D1 (de)	2003-04-17	Sulfamoylheteroarylpyrazolverbindungen zur Verwendung als analgetisches/entzündungshemmendes Mittel
DE60221098D1 (de)	2007-08-23	Kondensierte heterocyclische derivate
GB9801690D0 (en)	1998-03-25	Therapeutic agents
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DE69912581D1 (de)	2003-12-11	Biarylessigsäure-derivate und ihre verwendung als cox-2 inhibitoren
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DE69810760D1 (de)	2003-02-20	Verbindungen mit kondensierten ringen, verfahren zu ihrer herstellung und ihre anwendung
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ATE167855T1 (de)	1998-07-15	Propensäure derivate verwendbar als fungizide
CA2285535A1 (en)	1998-11-12	Benzimidazole derivative for treating allergy-related disease
DK0630367T3 (da)	2000-09-18	Hidtil ukendte arylindazoler og deres anvendelse som herbicider
ES2191621T3 (es)	2003-09-16	Tienocicloalqu(en)ilamino-1,3,5-triazinas substituidas.
WO2000077169A3 (en)	2001-07-05	(z)-styryl acetoxyphenyl sulfides as cyclooxygenase inhibitors
WO2000020399A3 (de)	2000-07-27	Verwendung von substituierten 5-hydroxypyrazolen, neue 5-hydroxypyrazole, verfahren zu deren herstellung, sowie sie enthaltende mittel
ATE243695T1 (de)	2003-07-15	5-bicycloindolverbindungen
ES2184633A1 (es)	2003-04-01	Procedimiento para la preparacion de derivados de 4-(imidazol-1-il) bencenosulfonamida.
ATE289316T1 (de)	2005-03-15	1-(2,5'-anhydro-lyxofuranosyl) thymine zur synthese von radiomarkierten fluor-3' deoxynucleotiden
SE9901237D0 (sv)	1999-04-06	Novel use