ATE361989T1 - Mit influenzavirus-hämagglutinin und influenza m2 pseudotypisierte retrovirusvektoren zur zuführung von genen - Google Patents
Mit influenzavirus-hämagglutinin und influenza m2 pseudotypisierte retrovirusvektoren zur zuführung von genenInfo
- Publication number
- ATE361989T1 ATE361989T1 AT03737362T AT03737362T ATE361989T1 AT E361989 T1 ATE361989 T1 AT E361989T1 AT 03737362 T AT03737362 T AT 03737362T AT 03737362 T AT03737362 T AT 03737362T AT E361989 T1 ATE361989 T1 AT E361989T1
- Authority
- AT
- Austria
- Prior art keywords
- influenza
- protein
- gene delivery
- virus hemagglutinin
- retrovirus vectors
- Prior art date
Links
- 206010022000 influenza Diseases 0.000 title abstract 3
- 241001430294 unidentified retrovirus Species 0.000 title abstract 2
- 101710154606 Hemagglutinin Proteins 0.000 title 1
- 101710093908 Outer capsid protein VP4 Proteins 0.000 title 1
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 title 1
- 101710176177 Protein A56 Proteins 0.000 title 1
- 238000001476 gene delivery Methods 0.000 title 1
- 239000000185 hemagglutinin Substances 0.000 title 1
- 241000712461 unidentified influenza virus Species 0.000 title 1
- 239000013598 vector Substances 0.000 title 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 3
- 239000002773 nucleotide Substances 0.000 abstract 3
- 125000003729 nucleotide group Chemical group 0.000 abstract 3
- 230000001177 retroviral effect Effects 0.000 abstract 3
- 101710091045 Envelope protein Proteins 0.000 abstract 2
- 101710188315 Protein X Proteins 0.000 abstract 2
- 102100021696 Syncytin-1 Human genes 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 101001039853 Sonchus yellow net virus Matrix protein Proteins 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000002463 transducing effect Effects 0.000 abstract 1
- 230000026683 transduction Effects 0.000 abstract 1
- 238000010361 transduction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15045—Special targeting system for viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
- C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Vending Machines For Individual Products (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0202569.0A GB0202569D0 (en) | 2002-02-04 | 2002-02-04 | Delivery means |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE361989T1 true ATE361989T1 (de) | 2007-06-15 |
Family
ID=9930369
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03737362T ATE361989T1 (de) | 2002-02-04 | 2003-02-04 | Mit influenzavirus-hämagglutinin und influenza m2 pseudotypisierte retrovirusvektoren zur zuführung von genen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7659113B2 (de) |
| EP (2) | EP1478759B1 (de) |
| AT (1) | ATE361989T1 (de) |
| AU (1) | AU2003244404A1 (de) |
| DE (1) | DE60313743T2 (de) |
| GB (1) | GB0202569D0 (de) |
| WO (1) | WO2003066868A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100807016B1 (ko) | 2000-06-01 | 2008-02-25 | 가부시키가이샤 디나벡크 겐큐쇼 | 헤마글루티닌 활성을 갖는 막단백질을 포함하는 슈도타입레트로바이러스 벡터 |
| ES2340499T3 (es) | 2001-06-05 | 2010-06-04 | Curevac Gmbh | Arnm de antigeno tumoral estabilizado con un contenido de g/c aumentado. |
| AU2003261931A1 (en) * | 2002-09-04 | 2004-03-29 | Dnavec Research Inc. | Process for producing virus vector containing membrane protein having sialic acid-binding activitiy in envelope with the use of gram-positive bacterium-origin neuraminidase |
| CA2627485C (en) | 2005-10-28 | 2017-02-21 | Katsuyuki Mitomo | Gene transfer into airway epithelial stem cell by using lentiviral vector pseudotyped with rna virus or dna virus spike protein |
| EP2044198A4 (de) * | 2006-07-27 | 2010-09-08 | Ligocyte Pharmaceuticals Inc | Chimärische influenza-virus-ähnliche partikel |
| EP2111233A2 (de) * | 2006-12-29 | 2009-10-28 | Institut Pasteur Of Shanghai | Mit influenza-hämagglutinin pseudotypisiertes lentivirus und anwendungsverfahren dafür |
| WO2009036063A1 (en) * | 2007-09-11 | 2009-03-19 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Pseudotyped retroviral vectors and methods of making and using them |
| WO2010085660A2 (en) | 2009-01-23 | 2010-07-29 | Roger Williams Hospital | Viral vectors encoding multiple highly homologous non-viral polypeptides and the use of same |
| JP6894236B2 (ja) * | 2014-03-26 | 2021-06-30 | デノボ バイオファーマ エルエルシー | 免疫刺激活性を有するレトロウイルスベクター |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999013905A1 (en) * | 1997-09-18 | 1999-03-25 | The Trustees Of The University Of Pennsylvania | Receptor-binding pocket mutants of influenza a virus hemagglutinin for use in targeted gene delivery |
| KR100807016B1 (ko) * | 2000-06-01 | 2008-02-25 | 가부시키가이샤 디나벡크 겐큐쇼 | 헤마글루티닌 활성을 갖는 막단백질을 포함하는 슈도타입레트로바이러스 벡터 |
-
2002
- 2002-02-04 GB GBGB0202569.0A patent/GB0202569D0/en not_active Ceased
-
2003
- 2003-02-04 DE DE60313743T patent/DE60313743T2/de not_active Expired - Lifetime
- 2003-02-04 EP EP03737362A patent/EP1478759B1/de not_active Expired - Lifetime
- 2003-02-04 EP EP07008912A patent/EP1813676B1/de not_active Expired - Lifetime
- 2003-02-04 AT AT03737362T patent/ATE361989T1/de active
- 2003-02-04 AU AU2003244404A patent/AU2003244404A1/en not_active Abandoned
- 2003-02-04 WO PCT/GB2003/000496 patent/WO2003066868A1/en not_active Ceased
-
2004
- 2004-08-04 US US10/910,845 patent/US7659113B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| GB0202569D0 (en) | 2002-03-20 |
| EP1813676A3 (de) | 2007-09-26 |
| EP1478759A1 (de) | 2004-11-24 |
| WO2003066868A1 (en) | 2003-08-14 |
| EP1813676A2 (de) | 2007-08-01 |
| EP1478759B1 (de) | 2007-05-09 |
| DE60313743T2 (de) | 2008-01-24 |
| EP1813676B1 (de) | 2012-07-25 |
| US20050123515A1 (en) | 2005-06-09 |
| US7659113B2 (en) | 2010-02-09 |
| DE60313743D1 (de) | 2007-06-21 |
| AU2003244404A1 (en) | 2003-09-02 |
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| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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