ATE362475T1 - Bekämpfng von parasiten in tieren durch anwendung von imidazo(1,2-b)pyridazinderivaten - Google Patents

Bekämpfng von parasiten in tieren durch anwendung von imidazo(1,2-b)pyridazinderivaten

Info

Publication number
ATE362475T1
ATE362475T1 AT04815474T AT04815474T ATE362475T1 AT E362475 T1 ATE362475 T1 AT E362475T1 AT 04815474 T AT04815474 T AT 04815474T AT 04815474 T AT04815474 T AT 04815474T AT E362475 T1 ATE362475 T1 AT E362475T1
Authority
AT
Austria
Prior art keywords
animals
imidazo
pyridazine derivatives
parasites
fighting parasites
Prior art date
Application number
AT04815474T
Other languages
English (en)
Inventor
Kevin Winzenberg
Craig Francis
David Sawutz
Ashit Ganguly
Original Assignee
Schering Plough Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Plough Ltd filed Critical Schering Plough Ltd
Application granted granted Critical
Publication of ATE362475T1 publication Critical patent/ATE362475T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT04815474T 2003-12-31 2004-12-22 Bekämpfng von parasiten in tieren durch anwendung von imidazo(1,2-b)pyridazinderivaten ATE362475T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53372903P 2003-12-31 2003-12-31

Publications (1)

Publication Number Publication Date
ATE362475T1 true ATE362475T1 (de) 2007-06-15

Family

ID=34748949

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04815474T ATE362475T1 (de) 2003-12-31 2004-12-22 Bekämpfng von parasiten in tieren durch anwendung von imidazo(1,2-b)pyridazinderivaten

Country Status (15)

Country Link
US (1) US7759349B2 (de)
EP (1) EP1699799B1 (de)
JP (1) JP4758909B2 (de)
KR (1) KR20060110344A (de)
CN (1) CN100582108C (de)
AT (1) ATE362475T1 (de)
AU (1) AU2004312506B2 (de)
BR (1) BRPI0418328A (de)
CA (1) CA2551867C (de)
DE (1) DE602004006536T2 (de)
ES (1) ES2285565T3 (de)
NZ (1) NZ548098A (de)
PL (1) PL380764A1 (de)
WO (1) WO2005066177A1 (de)
ZA (1) ZA200605299B (de)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7943160B2 (en) * 2002-05-09 2011-05-17 Scimetrics Limited Corp. Pest control methods
DE602005009381D1 (de) 2004-09-23 2008-10-09 Schering Plough Ltd Bekämpfung von parasiten in tieren durch verwendung neuer trifluormethansulfonanilidoximetherderivate
JP4750126B2 (ja) 2004-11-19 2011-08-17 シェーリング−プラウ・リミテッド 殺寄生虫薬2−フェニル−3−(1h−ピロール−2−イル)アクリロニトリル誘導体の使用による動物における寄生虫の制御
JPWO2006070943A1 (ja) * 2004-12-28 2008-06-12 武田薬品工業株式会社 縮合イミダゾール化合物およびその用途
EP1890547A2 (de) * 2005-06-09 2008-02-27 Schering-Plough Ltd. Kontrolle von parasiten bei tieren durch n-[(phenyloxy)phenyl]-1,1,1-trifluormethanesulfonamid und n-[(phenylsulfanyl)phenyl]-1,1,1-trifluormethanesulfonamid-derivate
US7750000B2 (en) 2005-09-02 2010-07-06 Bayer Schering Pharma Ag Substituted imidazo[1,2b]pyridazines as kinase inhibitors, their preparation and use as medicaments
DE102005042742A1 (de) * 2005-09-02 2007-03-08 Schering Ag Substituierte Imidazo[1,2b]pyridazine als Kinase-Inhibitoren, deren Herstellung und Verwendung als Arzneimittel
US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
TW200803903A (en) * 2006-04-28 2008-01-16 Nihon Mediphysics Co Ltd Novel compound having affinity to amyloid
JP5238496B2 (ja) * 2006-05-19 2013-07-17 日本メジフィジックス株式会社 新規アミロイド親和性化合物
CN101501033B (zh) 2006-06-21 2012-08-01 通用电气医疗有限公司 对淀粉状蛋白具有亲和性的化合物
DE102006029447A1 (de) * 2006-06-21 2007-12-27 Bayer Schering Pharma Ag Oxo-substituierte Imidazo[1,2b]pyridazine, deren Herstellung und Verwendung als Arzneimittel
WO2008016192A2 (en) 2006-08-04 2008-02-07 Takeda Pharmaceutical Company Limited Fused heterocyclic derivative and use thereof
CN101595108A (zh) * 2006-11-30 2009-12-02 日本医事物理股份有限公司 对淀粉状蛋白具有亲和性的新化合物
WO2008076256A1 (en) * 2006-12-13 2008-06-26 Schering-Plough Ltd. Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof
CN101605756A (zh) * 2006-12-13 2009-12-16 先灵-普劳有限公司 氟苯尼考及其类似物的水溶性前药
WO2008072682A1 (ja) * 2006-12-15 2008-06-19 Daiichi Sankyo Company, Limited イミダゾ[1,2-b]ピリダジン誘導体
EP2119458B9 (de) 2007-02-13 2013-08-21 Nihon Medi-Physics Co., Ltd. Verfahren zur herstellung eines abbildungsmittels zur strahlendiagnose
WO2008133192A1 (ja) * 2007-04-19 2008-11-06 Takeda Pharmaceutical Company Limited 縮合イミダゾール化合物およびその用途
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
DK2182945T3 (en) 2007-06-27 2015-11-16 Du Pont PROCEDURE TO COMBAT PESTS WITH ANIMALS
KR101150581B1 (ko) * 2007-07-26 2012-06-11 노파르티스 아게 유기 화합물
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
TW200918102A (en) * 2007-10-24 2009-05-01 Nihon Mediphysics Co Ltd Novel compound having affinity for amyloid
KR20100101577A (ko) * 2007-10-30 2010-09-17 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물의 사용 및 제조 방법
KR20100089858A (ko) * 2007-10-30 2010-08-12 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물의 사용 및 제조 방법
US7868001B2 (en) 2007-11-02 2011-01-11 Hutchison Medipharma Enterprises Limited Cytokine inhibitors
TWI491610B (zh) * 2008-10-09 2015-07-11 必治妥美雅史谷比公司 作為激酶抑制劑之咪唑并嗒腈
AU2010279587A1 (en) 2009-08-05 2012-02-09 E. I. Du Pont De Nemours And Company Mesoionic pesticides
EP2461684A2 (de) 2009-08-05 2012-06-13 E. I. du Pont de Nemours and Company Mesoionische pestizide
UA110924C2 (uk) 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
WO2011095581A1 (en) 2010-02-05 2011-08-11 Intervet International B.V. S piroindoline compounds for use as anthelminthi cs
ES2624845T3 (es) 2010-09-29 2017-07-17 Intervet International B.V. Compuestos de N-heteroarilo con unidad de puente cíclico para el tratamiento de enfermedades parasitarias
RU2596185C2 (ru) 2010-09-29 2016-08-27 Интервет Интернэшнл Б.В. N-гетероарильные соединения
WO2012087630A1 (en) 2010-12-20 2012-06-28 E.I. Du Pont De Nemours And Company Pyridine and pyrimidine compounds for controlling invertebrate
TWI617559B (zh) * 2010-12-22 2018-03-11 江蘇恆瑞醫藥股份有限公司 2-芳基咪唑并[1,2-b]嗒.2-苯基咪唑并[1,2-a]吡啶,和2-苯基咪唑并[1,2-a]吡衍生物
US20140113934A1 (en) 2011-06-20 2014-04-24 E I Du Pont De Nemours And Company Heterocyclic compounds for treating helminth infections
WO2013017678A1 (en) 2011-08-04 2013-02-07 Intervet International B.V. Novel spiroindoline compounds
JP2015502936A (ja) 2011-11-28 2015-01-29 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーE.I.Du Pont De Nemours And Company スルホンアミド駆虫薬
WO2013144180A1 (en) 2012-03-28 2013-10-03 Intervet International B.V. Heteroaryl compounds with cyclic bridging unit for use in the treatment helminth infection
EP2831042B1 (de) 2012-03-28 2019-07-31 Intervet International B.V. Heteroaryl-verbindungen mit azyklischer brückeneinheit
WO2013158422A1 (en) 2012-04-17 2013-10-24 E. I. Du Pont De Nemours And Company Heterocyclic compounds for controlling invertebrate pests
WO2014099837A1 (en) 2012-12-18 2014-06-26 E. I. Du Pont De Nemours And Company Sulfonamide anthelmintics
ES2779532T3 (es) 2015-04-08 2020-08-18 Bayer Cropscience Ag Derivados de imidazo[1,2a]piridin-2-ilo como pesticidas y sus productos intermedios
AR105607A1 (es) 2015-08-07 2017-10-18 Bayer Cropscience Ag Derivados heterocíclicos condensados sustituidos por 2-(het)arilo como pesticidas
CN108430986B (zh) 2015-10-26 2021-08-31 拜耳作物科学股份公司 作为有害生物控制剂的稠合双环杂环衍生物
WO2017093180A1 (de) 2015-12-01 2017-06-08 Bayer Cropscience Aktiengesellschaft Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel
WO2017144341A1 (de) 2016-02-23 2017-08-31 Bayer Cropscience Aktiengesellschaft Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel
WO2017174414A1 (de) 2016-04-05 2017-10-12 Bayer Cropscience Aktiengesellschaft Naphthalin-derivate als schädlingsbekämpfungsmittel
EP3241830A1 (de) 2016-05-04 2017-11-08 Bayer CropScience Aktiengesellschaft Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel
US10561145B2 (en) * 2016-07-19 2020-02-18 Bayer Cropscience Aktiengesellschaft Fused bicyclic heterocycle derivatives as pesticides
AU2017314083B2 (en) 2016-08-15 2020-12-10 Bayer Aktiengesellschaft Condensed bicyclic heterocycle derivatives as pest control agents
CN109963860A (zh) 2016-09-19 2019-07-02 拜耳作物科学股份公司 吡唑并[1,5-a]吡啶衍生物及其作为农药的用途
WO2018065288A1 (de) 2016-10-07 2018-04-12 Bayer Cropscience Aktiengesellschaft 2-[2-phenyl-1-(sulfonylmethyl)vinyl]-imidazo[4,5-b]pyridin-derivate und verwandte verbindungen als schädlingsbekämpfungsmittel im pflanzenschutz
TW201837026A (zh) 2017-01-10 2018-10-16 德商拜耳廠股份有限公司 作為除害劑之雜環衍生物(二)
KR102515694B1 (ko) 2017-01-10 2023-03-29 바이엘 악티엔게젤샤프트 해충 방제제로서의 헤테로사이클 유도체
GB201700692D0 (en) * 2017-01-16 2017-03-01 Salvensis Novel compounds and their use in the treatment of schistosomiasis
WO2018138050A1 (de) 2017-01-26 2018-08-02 Bayer Aktiengesellschaft Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel
AU2018257372B2 (en) 2017-04-24 2022-06-02 Bayer Aktiengesellschaft Condensed bicyclic heterocyclic-compound derivatives as pest control agents
EP3305786A3 (de) 2018-01-22 2018-07-25 Bayer CropScience Aktiengesellschaft Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel
CN111741958A (zh) 2018-02-21 2020-10-02 拜耳公司 作为害虫防治剂的稠合双环杂环衍生物
WO2020002593A1 (en) 2018-06-29 2020-01-02 Intervet International B.V. Compound for use against helminthic infection
MX2021000293A (es) 2018-07-09 2021-07-15 Boehringer Ingelheim Animal Health Usa Inc Compuestos heterociclicos antihelminticos.
CN113710669A (zh) 2019-02-26 2021-11-26 拜耳公司 作为农药的稠合双环杂环衍生物
PH12021552065A1 (en) 2019-02-26 2022-05-23 Bayer Ag Condensed bicyclic heterocyclic derivatives as pest control agents
KR20220002890A (ko) 2019-03-19 2022-01-07 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 구충성 아자-벤조티오펜 및 아자-벤조푸란 화합물
MX2022007671A (es) 2019-12-18 2022-07-19 Intervet Int Bv Compuestos antihelminticos que comprenden una estructura de azaindoles.
JP2023507173A (ja) 2019-12-18 2023-02-21 インターベット インターナショナル ベー. フェー. キノリン構造を含む駆虫剤化合物
IL297963A (en) 2020-05-07 2023-01-01 Adorx Therapeutics Ltd Antagonists of the adenosine a2a receptor
BR112022024156A2 (pt) * 2020-05-29 2023-02-14 Boehringer Ingelheim Animal Health Usa Inc Compostos heterocílicos antelmínticos
WO2022122988A1 (en) 2020-12-11 2022-06-16 Intervet International B.V. Anthelmintic compounds comprising a thienopyridine structure
GB202019622D0 (en) * 2020-12-11 2021-01-27 Adorx Therapeutics Ltd Antagonist compounds
WO2023073641A1 (en) 2021-11-01 2023-05-04 Boehringer Ingelheim Vetmedica Gmbh Anthelmintic pyrrolopyridazine compounds
CN121620507A (zh) 2023-08-02 2026-03-06 英特维特国际股份有限公司 具有驱虫活性的甲酰胺-4-喹啉化合物
WO2026115027A1 (en) 2024-11-28 2026-06-04 Intervet International B.V. Carboxamide-4-quinoline compounds with anthelmintic activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725407A (en) * 1971-04-08 1973-04-03 American Cyanamid Co 6-substituted amino-3-nitroimidazo(1,2-b)pyridazines and methods of preparing the same
US3905974A (en) * 1972-09-28 1975-09-16 American Cyanamid Co 6-Substituted oxo and thio-3-nitroimidazo(1,2-b)-pyridazines and methods of preparing same
DD202692A5 (de) 1979-12-04 1983-09-28 Ciba Geigy Verfahren zur herstellung neuer derivate des 2-amino-aethanols

Also Published As

Publication number Publication date
CN1922181A (zh) 2007-02-28
JP4758909B2 (ja) 2011-08-31
CN100582108C (zh) 2010-01-20
DE602004006536T2 (de) 2008-01-31
US7759349B2 (en) 2010-07-20
NZ548098A (en) 2010-05-28
US20050182059A1 (en) 2005-08-18
DE602004006536D1 (de) 2007-06-28
AU2004312506B2 (en) 2011-08-04
CA2551867C (en) 2010-08-17
HK1091207A1 (en) 2007-01-12
EP1699799A1 (de) 2006-09-13
ES2285565T3 (es) 2007-11-16
KR20060110344A (ko) 2006-10-24
JP2007517043A (ja) 2007-06-28
WO2005066177A1 (en) 2005-07-21
BRPI0418328A (pt) 2007-05-02
CA2551867A1 (en) 2005-07-21
EP1699799B1 (de) 2007-05-16
PL380764A1 (pl) 2007-03-19
ZA200605299B (en) 2007-03-28
AU2004312506A1 (en) 2005-07-21

Similar Documents

Publication Publication Date Title
DE602004006536D1 (de) Bekämpfng von parasiten in tieren durch anwendung von imidazoä1,2-büpyridazinderivaten
DE60315146D1 (de) Heteroarylsubstituierte biphenylderivate als inhibitoren von p38-kinase
NO20054082L (no) Pyrazol`1,5-A! 1,3,5! triazinderivater som kannabinoidreseptorligander
DK1333833T3 (da) Ny trisubstitueret 8H-pyridol[2,3-d]pyrimidin-7-on-forbindelse til behandling af CSBP/RK/p38-kinnasemedierede sygdomme
BR0014352A (pt) Cetoenóis espirocìclicos substituìdos por trifluormetila
SI1474395T1 (sl) Nikotinamidni derivati, uporabni kot inhibitorji p38
WO2006034333A3 (en) Control of parasites in animals by the use of novel trifluoromethanesulfonanilide oxime ether derivatives
CA2492096A1 (en) Cis-alkoxy-substituted spirocyclic 1-h-pyrrolidine-2,4-dione derivatives serving as pesticides
DK1215965T3 (da) Fremgangsmåde og præparat til bekæmpelse af arthropoder
ATE472551T1 (de) Tocopherolmodifizierte therapeutische arzneimittelverbindung
ATE433973T1 (de) Azolylaminoazine als inhibitoren von proteinkinasen
LU91710I9 (de)
EA200300929A1 (ru) Новые лекарственные композиции на основе антихолинергических средств и ингибиторов pde-iv
DE502004002571D1 (de) Substituierte 3-pyrrolidin-indol-derivate
ATE389651T1 (de) Als inhibitoren von c-met geeignete pyrrolzusammensetzungen
WO2006055565A3 (en) Control of parasites in animals by the use of parasiticidal 2-phenyl-3-(1h-pyrrol-2-yl) acrylonitrile derivatives
WO2006047032A3 (en) Indole compounds useful as serotonin selective agents
WO2004069160A3 (en) Chemical compounds
MXPA02009313A (es) Acilsulfimidas heterociclicas, un metodo para su produccion, agentes que contienen las mismas y su uso como plaguicidas.
WO2004019879A3 (en) Motilide compounds
WO2004034985A3 (en) Chemical compounds
UY28049A1 (es) Derivados de (6,7-dihidro-5h-imidazo(1,2-a) imidazol-3-sulfonilamino)-propionamida
WO2002076396A3 (en) Compounds useful as kinase inhibitors for the treatment of hyperproliferative diseases
ATE381568T1 (de) Pyrano(2,3-c)imidazo(1,2-a)pyridin-derivate zur behandlung von gastrointestinalen erkrankungen
WO2003064385A3 (de) Delta1-pyrroline und deren verwendung als schädlingsbekämpfungsmittel

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties