ATE362479T1 - 14 bis 15 gliedrige makrolide mit antibakterieller aktivität - Google Patents

14 bis 15 gliedrige makrolide mit antibakterieller aktivität

Info

Publication number
ATE362479T1
ATE362479T1 AT02779670T AT02779670T ATE362479T1 AT E362479 T1 ATE362479 T1 AT E362479T1 AT 02779670 T AT02779670 T AT 02779670T AT 02779670 T AT02779670 T AT 02779670T AT E362479 T1 ATE362479 T1 AT E362479T1
Authority
AT
Austria
Prior art keywords
macrolids
antibacterial activity
antibacterial
activity
element macrolids
Prior art date
Application number
AT02779670T
Other languages
English (en)
Inventor
Sulejman Alihodzic
Daniele Andreotti
Andrea Berdik
Ilaria Bientinesi
Stefano Biondi
Manuela Ciraco
Federica Damiani
Marko Djerek
Miljenko Dumic
Vesna Erakovic
Antun Hutinec
Gorjana Lazarevski
Sergio Lociuro
Natasa Marsic
Zorica Marusic-Istuk
Stjepan Mutak
Alfredo Paio
Drazen Pavlovic
Anna Quaglia
Vlado Stimac
Jessica Tibasco
Wolfgang Schoenfeld
Original Assignee
Glaxo Group Ltd
Glaxosmithkline Zagreb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd, Glaxosmithkline Zagreb filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE362479T1 publication Critical patent/ATE362479T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
AT02779670T 2001-11-14 2002-11-13 14 bis 15 gliedrige makrolide mit antibakterieller aktivität ATE362479T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0127349.9A GB0127349D0 (en) 2001-11-14 2001-11-14 Macrolides

Publications (1)

Publication Number Publication Date
ATE362479T1 true ATE362479T1 (de) 2007-06-15

Family

ID=9925777

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02779670T ATE362479T1 (de) 2001-11-14 2002-11-13 14 bis 15 gliedrige makrolide mit antibakterieller aktivität

Country Status (20)

Country Link
US (1) US7202221B2 (de)
EP (1) EP1453846B1 (de)
JP (1) JP2005515978A (de)
CN (1) CN1307194C (de)
AR (1) AR037371A1 (de)
AT (1) ATE362479T1 (de)
BR (1) BR0214132A (de)
CA (1) CA2466975A1 (de)
DE (1) DE60220180T2 (de)
EA (1) EA007433B1 (de)
ES (1) ES2287332T3 (de)
GB (1) GB0127349D0 (de)
HR (1) HRP20040433A2 (de)
HU (1) HUP0402225A3 (de)
IL (1) IL161710A0 (de)
PL (1) PL371472A1 (de)
RS (1) RS41904A (de)
UA (1) UA77210C2 (de)
WO (1) WO2003042228A1 (de)
ZA (1) ZA200403684B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6995143B2 (en) * 2002-02-28 2006-02-07 Basilea Pharmaceutica Ag Macrolides with antibacterial activity
WO2005070918A1 (en) 2002-05-13 2005-08-04 Enanta Pharmaceuticals, Inc. Process for the preparation of t-11 bicyclic erythromycin derivatives
US7910558B2 (en) 2002-05-13 2011-03-22 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
US6764998B1 (en) 2003-06-18 2004-07-20 Enanta Pharmaceuticals, Inc. 6,11-4C-bicyclic 9a-azalide derivatives
US7135573B2 (en) 2002-05-13 2006-11-14 Enanta Pharmaceuticals, Inc. Processes for the preparation of O-(6-Pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine
DK1503759T3 (da) * 2002-05-14 2009-04-14 Univ California Substituerede quinoloncarboxylsyrer, deres derivater, virkningssted og anvendelser heraf
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
GB0225384D0 (en) * 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds
US6645941B1 (en) 2003-03-26 2003-11-11 Enanta Pharmaceuticals, Inc. 6,11-3C-bicyclic 9a-azalide derivatives
GB0310980D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
GB0310979D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
ES2278319T3 (es) * 2003-05-13 2007-08-01 Glaxo Group Limited Nuevos compuestos con 14 y 15 miembros en el anillo.
GB0310986D0 (en) 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
GB0310984D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
WO2005030227A1 (en) 2003-09-23 2005-04-07 Enanta Pharmaceuticals, Inc. 9a, 11-3C-BICYCLIC 9a-AZALIDE DERIVATIVES
WO2005070113A2 (en) 2004-01-09 2005-08-04 Enanta Pharmaceuticals, Inc. 9n-substituted 6-11 bicyclic erythromycin derivatives
EP1723159B1 (de) 2004-02-27 2019-06-12 Melinta Therapeutics, Inc. Makrozyklische verbindungen, deren herstellung und verwendung
WO2005108412A1 (en) * 2004-05-06 2005-11-17 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Ester linked macrolides useful for the treatment of microbial infections
JP2007536372A (ja) * 2004-05-06 2007-12-13 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ 微生物感染症の治療に有用なカルバミン酸エステル結合マクロライド
WO2006047167A2 (en) * 2004-10-21 2006-05-04 Janssen Pharmaceutica, N.V. 9 alkyl and 9 alkylidenyl 6-0 alkyl-11, 12 carbamate ketolide antimicrobials
GB0424961D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
GB0424959D0 (en) 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
GB0424951D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
GB0424958D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
BRPI0716408A2 (pt) 2006-08-09 2013-09-24 Basilea Pharmaceutica Ag macrolÍdeos éteis doenÇa inflamatària e alÉrgica
CA2661538A1 (en) 2006-08-24 2008-02-28 Wockhardt Research Centre Novel macrolides and ketolides having antimicrobial activity
WO2009106419A1 (en) 2008-02-08 2009-09-03 Basilea Pharmaceutica Ag New macrolides and their use
ES2561332T3 (es) 2009-05-27 2016-02-25 Wockhardt Limited Compuestos cetólidos que tienen actividad antimicrobiana
PT2673285T (pt) 2010-12-09 2017-10-19 Wockhardt Ltd Resumo
BR112013019283A2 (pt) * 2011-01-31 2016-09-13 Meiji Seika Pharma Co Ltd composto, fármaco, composição farmacêutica e uso
JP5718488B2 (ja) 2011-03-01 2015-05-13 ウォックハート リミテッド ケトライド中間体の調製方法
CN119060110A (zh) * 2023-05-30 2024-12-03 北京理工大学 一种红霉素衍生物及其制备方法和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0126344A2 (de) 1983-05-20 1984-11-28 Abbott Laboratories Tripeptidester von therapeutischen Mitteln
US4742049A (en) * 1986-06-04 1988-05-03 Abbott Laboratories Semisynthetic erythromycin antibiotics
WO1990011288A1 (en) 1989-03-28 1990-10-04 Abbott Laboratories Erythromycin derivatives
CA2064634C (en) * 1991-04-04 1998-08-04 James V. Heck 9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions
DE69734678T2 (de) 1996-05-07 2006-08-17 Abbott Laboratories, Abbott Park 6-0-substitutierte eryththromycin-verbindungen und verfahrenen zu ihrer herstellung
EP0895999A1 (de) * 1997-08-06 1999-02-10 Pfizer Products Inc. C-4"-substituierte Macrolidantibiotica
US6262030B1 (en) 1998-11-03 2001-07-17 Pfizer Inc. Erythromycin derivatives
HUP0201516A3 (en) 1999-05-24 2003-03-28 Pfizer Prod Inc 13-methyl-erythromycin derivatives, process for their preparation and pharmaceutical compositions containing them
DK1206476T3 (da) 1999-08-24 2006-05-15 Abbott Lab 9a-azalider med antibakteriel virkning
ATE312839T1 (de) 2000-02-24 2005-12-15 Abbott Lab Anti-infektionsmittel, die gegen gegenüber mehreren arzneimitteln resistente bakterienstämme nützlich sind
US6946446B2 (en) 2000-02-24 2005-09-20 Abbott Laboratories Anti-infective agents useful against multidrug-resistant strains of bacteria
JP2002173498A (ja) 2000-09-27 2002-06-21 Hokuriku Seiyaku Co Ltd エリスロマイシン誘導体
GB0025688D0 (en) * 2000-10-19 2000-12-06 Glaxo Group Ltd Macrolides

Also Published As

Publication number Publication date
CN1612888A (zh) 2005-05-04
RS41904A (sr) 2006-10-27
WO2003042228A1 (en) 2003-05-22
PL371472A1 (en) 2005-06-13
DE60220180T2 (de) 2008-01-17
UA77210C2 (en) 2006-11-15
HUP0402225A2 (hu) 2005-02-28
HRP20040433A2 (en) 2005-04-30
ES2287332T3 (es) 2007-12-16
ZA200403684B (en) 2005-09-13
EP1453846A1 (de) 2004-09-08
BR0214132A (pt) 2004-09-14
CA2466975A1 (en) 2003-05-22
GB0127349D0 (en) 2002-01-02
EA007433B1 (ru) 2006-10-27
CN1307194C (zh) 2007-03-28
HUP0402225A3 (en) 2006-01-30
AR037371A1 (es) 2004-11-03
JP2005515978A (ja) 2005-06-02
US7202221B2 (en) 2007-04-10
EA200400536A1 (ru) 2004-12-30
EP1453846B1 (de) 2007-05-16
US20050080025A1 (en) 2005-04-14
DE60220180D1 (de) 2007-06-28
IL161710A0 (en) 2004-09-27

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties