ATE362524T1 - Immortalisierte zelllinien für die wachstum von viren - Google Patents

Immortalisierte zelllinien für die wachstum von viren

Info

Publication number
ATE362524T1
ATE362524T1 AT97938334T AT97938334T ATE362524T1 AT E362524 T1 ATE362524 T1 AT E362524T1 AT 97938334 T AT97938334 T AT 97938334T AT 97938334 T AT97938334 T AT 97938334T AT E362524 T1 ATE362524 T1 AT E362524T1
Authority
AT
Austria
Prior art keywords
cell lines
immortalized cell
virus growth
virus
growth
Prior art date
Application number
AT97938334T
Other languages
English (en)
Inventor
Douglas Foster
Linda Foster
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota filed Critical Univ Minnesota
Application granted granted Critical
Publication of ATE362524T1 publication Critical patent/ATE362524T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C12N15/867—Retroviral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16651—Methods of production or purification of viral material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12051—Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Rheumatology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT97938334T 1996-08-13 1997-08-13 Immortalisierte zelllinien für die wachstum von viren ATE362524T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/696,200 US5672485A (en) 1996-08-13 1996-08-13 Immortalized cell lines for virus growth

Publications (1)

Publication Number Publication Date
ATE362524T1 true ATE362524T1 (de) 2007-06-15

Family

ID=24796108

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97938334T ATE362524T1 (de) 1996-08-13 1997-08-13 Immortalisierte zelllinien für die wachstum von viren

Country Status (28)

Country Link
US (4) US5672485A (de)
EP (1) EP0920491B1 (de)
JP (3) JP3754088B2 (de)
KR (1) KR100375871B1 (de)
CN (1) CN1228119B (de)
AR (1) AR008294A1 (de)
AT (1) ATE362524T1 (de)
AU (1) AU726820B2 (de)
BR (1) BR9711067A (de)
CA (1) CA2263725C (de)
CO (1) CO4700552A1 (de)
DE (1) DE69737735T2 (de)
DK (1) DK0920491T3 (de)
DZ (1) DZ2291A1 (de)
ES (1) ES2285738T3 (de)
GT (1) GT199700091A (de)
HN (1) HN1997000124A (de)
HU (1) HU226658B1 (de)
IL (4) IL158302A0 (de)
MA (1) MA24303A1 (de)
MY (1) MY125594A (de)
NZ (1) NZ334147A (de)
PE (1) PE108198A1 (de)
PT (1) PT920491E (de)
SV (1) SV1997000071A (de)
UY (1) UY24668A1 (de)
WO (1) WO1998006824A1 (de)
ZA (1) ZA977216B (de)

Families Citing this family (65)

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US5672485A (en) * 1996-08-13 1997-09-30 Regents Of The University Of Minnesota Immortalized cell lines for virus growth
US6150505A (en) * 1997-09-19 2000-11-21 Hadasit Medical Research Services & Development Ltd. Fibrin microbeads prepared from fibrinogen, thrombin and factor XIII
US6821741B1 (en) 2001-04-27 2004-11-23 University Hospitals Of Cleveland Cells for detection of enteroviruses
US6552172B2 (en) * 2001-08-30 2003-04-22 Habto Biotech, Inc. Fibrin nanoparticles and uses thereof
US20040023358A1 (en) * 2001-12-21 2004-02-05 Wyeth Avian embryo particulate biomass for the production of virus antigens
FR2836924B1 (fr) 2002-03-08 2005-01-14 Vivalis Lignees de cellules aviaires utiles pour la production de substances d'interet
US20090217404A1 (en) * 2002-09-27 2009-08-27 Lowe Scott W Cell-based RNA interference and related methods and compositions
WO2004031450A1 (ja) * 2002-09-30 2004-04-15 Honda Giken Kogyo Kabushiki Kaisha 水素活性化装置
CA2510229A1 (en) * 2002-12-13 2004-07-08 Aventis Pasteur, Inc. Production of alvac on avian embryonic stem cells
US20060294604A1 (en) * 2003-02-17 2006-12-28 Fridman Jordan S Model for studying the role of genes in tumor resistance to chemotherapy
US20090186839A1 (en) * 2003-02-17 2009-07-23 Cold Spring Harbor Laboratory Model for studying the role of genes in chemoresistance
US20050273873A1 (en) * 2003-03-07 2005-12-08 Avigenics, Inc. Genomic modification
US20050198700A1 (en) * 2003-03-07 2005-09-08 Avigenics, Inc. Genomic modification
WO2004080162A2 (en) * 2003-03-07 2004-09-23 Avigenics, Inc. Integrase mediated avian transgenesis
US20040255345A1 (en) * 2003-03-07 2004-12-16 Rapp Jeffrey C. Production of transgenic avians
US20050034186A1 (en) * 2003-03-07 2005-02-10 Harvey Alex J. Site specific nucleic acid integration
PT1646715E (pt) 2003-07-22 2010-08-09 Vivalis Produção de poxvírus com linhagem das células aviarias aderentes ou não aderentes
WO2005028634A2 (en) * 2003-09-18 2005-03-31 Emory University Improved mva vaccines
EP1528101A1 (de) 2003-11-03 2005-05-04 ProBioGen AG Immortalisierte Vogel-Zelllinien für die Produktion von Viren
US20060123504A1 (en) * 2004-12-07 2006-06-08 Avigenics, Inc. Methods of producing polyclonal antibodies
US20060174364A1 (en) * 2004-03-01 2006-08-03 Avigenics, Inc. Artificial chromosomes and transchromosomic avians
WO2006042214A1 (en) * 2004-10-08 2006-04-20 Avigenics, Inc. Modified integrase and methods of use
US8137907B2 (en) * 2005-01-03 2012-03-20 Cold Spring Harbor Laboratory Orthotopic and genetically tractable non-human animal model for liver cancer and the uses thereof
FR2884255B1 (fr) 2005-04-11 2010-11-05 Vivalis Utilisation de lignees de cellules souches aviaires ebx pour la production de vaccin contre la grippe
CA2610265A1 (en) * 2005-05-31 2007-05-10 Cold Spring Harbor Laboratory Methods for producing micrornas
TR201909425T4 (tr) 2005-10-05 2019-07-22 Alexion Pharma Inc Yüksek ti̇treli̇ vi̇rüsün hizli üreti̇mi̇
ES2611975T3 (es) 2006-06-20 2017-05-11 Transgene S.A. Procedimiento para producir poxvirus y composiciones de poxvirus
CN100443588C (zh) * 2006-12-11 2008-12-17 中国农业科学院北京畜牧兽医研究所 静宁鸡胚成纤维细胞系及其培养方法
US8213704B2 (en) * 2007-05-09 2012-07-03 Kla-Tencor Corp. Methods and systems for detecting defects in a reticle design pattern
EP2014279A1 (de) * 2007-06-22 2009-01-14 Pevion Biotech AG Virosomen enthaltend Haemagglutinin, das von über Zelllinien hergestellten Influenza-Viren stammt, Zusammensetzungen, Herstellungsverfahren, Verwendung davon
US8361788B2 (en) * 2007-07-03 2013-01-29 Transgene S.A. Immortalized avian cell lines comprising E1A nucleic acid sequences
US8357531B2 (en) 2007-07-03 2013-01-22 Transgene S.A. Immortalized avian cell lines
US8901288B2 (en) * 2007-10-26 2014-12-02 Cold Spring Harbor Laboratory High throughput methods for functionally determining RNA interference efficiency
KR20140096162A (ko) * 2008-02-25 2014-08-04 백스터 인터내셔널 인코포레이티드 연속 세포주 제조 방법
NZ596595A (en) * 2009-05-12 2013-05-31 Transgene Sa Method for orthopoxvirus production and purification
WO2010144797A2 (en) 2009-06-12 2010-12-16 Vaccine Technologies, Incorporated Influenza vaccines with enhanced immunogenicity and uses thereof
WO2012010280A1 (en) 2010-07-20 2012-01-26 Bavarian Nordic A/S Method for harvesting expression products
FR3008992A1 (fr) 2013-07-25 2015-01-30 Agronomique Inst Nat Rech Procede de selection d'une lignee cellulaire permissive pour la replication de virus aviaires
AU2015357225B2 (en) 2014-12-01 2020-04-09 Transgene Sa Stable liquid vaccinia virus formulations
JP6546659B2 (ja) * 2014-12-04 2019-07-17 インターベット インターナショナル ベー． フェー． 不死化ニワトリ胚線維芽細胞
ES3011733T3 (en) 2015-02-13 2025-04-08 Transgene Immunotherapeutic vaccine and antibody combination therapy
KR101768581B1 (ko) * 2015-08-13 2017-08-17 전북대학교 산학협력단 자발적 불멸화된 체세포의 단일 세포로부터 리프로그래밍 세포주의 제조방법
US20190144831A1 (en) * 2015-12-11 2019-05-16 Intervet Inc. Immortalised chicken embryonic epithelial kidney cells
EP3452081A1 (de) 2016-05-04 2019-03-13 Transgene SA Kombinationstherapie mit cpg-tlr9-liganden
IL302693B2 (en) * 2016-07-11 2025-10-01 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Methods and systems for growing cells in culture
EP3522920A2 (de) 2016-10-10 2019-08-14 Transgene SA Immuntherapeutisches produkt und mdsc-modulator-kombinationstherapie
US20200179507A1 (en) 2016-11-17 2020-06-11 Regents Of The University Of Minnesota Immortalized cell lines and methods of use
CA3061678A1 (en) 2017-05-15 2018-11-22 Janssen Vaccines & Prevention B.V. Stable virus-containing composition
US11052147B2 (en) 2017-05-15 2021-07-06 Janssen Vaccines & Prevention B.V. Stable virus-containing composition
JP7334124B2 (ja) 2017-06-21 2023-08-28 トランジェーヌ 個別化ワクチン
CN107858323B (zh) * 2017-11-08 2020-10-09 广东省生物资源应用研究所 一种红耳龟胚胎成纤维细胞系及其构建方法
CN109234239B (zh) * 2018-07-13 2021-09-14 广东永顺生物制药股份有限公司 一种鸭瘟病毒的培养方法
EP3847246A1 (de) 2018-09-06 2021-07-14 Bavarian Nordic A/S Pockenviruszusammensetzungen mit verbesserter lagerung
US12478571B2 (en) 2018-12-17 2025-11-25 Pontis Biologics, Inc. Enzyme based compositions and methods for removing dental calculi
MX2022007579A (es) 2019-12-20 2022-07-19 Intervet Int Bv Vacuna de vector hvt multivalente.
WO2021180943A1 (en) 2020-03-12 2021-09-16 Bavarian Nordic A/S Compositions improving poxvirus stability
CN116322740A (zh) 2020-07-13 2023-06-23 特兰斯吉恩股份有限公司 免疫抑制的治疗
EP4210740A1 (de) 2020-09-07 2023-07-19 Intervet International B.V. Ha-stamm-impfstoff für ha-antikörper-positive targets
WO2022136623A1 (en) 2020-12-24 2022-06-30 Intervet International B.V. Multivalent hvt vector vaccine
EP4370150A1 (de) 2021-07-13 2024-05-22 Intervet International B.V. Überwindung von antikörperinterferenz bei vögeln
WO2023213764A1 (en) 2022-05-02 2023-11-09 Transgene Fusion polypeptide comprising an anti-pd-l1 sdab and a member of the tnfsf
WO2023213763A1 (en) 2022-05-02 2023-11-09 Transgene Poxvirus encoding a binding agent comprising an anti- pd-l1 sdab
US20250352642A1 (en) 2022-05-05 2025-11-20 Intervet Inc. New multivalent hvt vector vaccine
WO2025074921A1 (ja) * 2023-10-06 2025-04-10 株式会社微生物化学研究所 ウイルスの生産方法
CN121006317B (zh) * 2025-10-22 2026-02-06 海南大学三亚南繁研究院 一种永生化鸡胚肾上皮样细胞及其制备方法和应用

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JP3058438B2 (ja) * 1990-10-19 2000-07-04 財団法人化学及血清療法研究所 ヒト肝臓組織特異的ウイルスの感染可能な霊長類の不死化肝細胞およびその調製方法
US5672485A (en) * 1996-08-13 1997-09-30 Regents Of The University Of Minnesota Immortalized cell lines for virus growth

Also Published As

Publication number Publication date
CA2263725C (en) 2002-10-15
CN1228119A (zh) 1999-09-08
ZA977216B (en) 1998-02-19
DE69737735D1 (de) 2007-06-28
KR100375871B1 (ko) 2003-03-10
JP2006320328A (ja) 2006-11-30
DZ2291A1 (fr) 2002-12-25
EP0920491A1 (de) 1999-06-09
CN1228119B (zh) 2012-04-04
GT199700091A (es) 1997-08-12
US5672485A (en) 1997-09-30
HUP0000188A2 (hu) 2000-06-28
MY125594A (en) 2006-08-30
US5879924A (en) 1999-03-09
HUP0000188A3 (en) 2005-11-28
HN1997000124A (es) 1999-03-19
PE108198A1 (es) 1999-01-21
DK0920491T3 (da) 2007-09-17
IL158303A0 (en) 2004-05-12
JP2000516095A (ja) 2000-12-05
CO4700552A1 (es) 1998-12-29
AU726820B2 (en) 2000-11-23
US6207415B1 (en) 2001-03-27
SV1997000071A (es) 2000-07-06
HU226658B1 (en) 2009-06-29
MA24303A1 (fr) 1998-04-01
PT920491E (pt) 2007-07-27
EP0920491B1 (de) 2007-05-16
IL128511A0 (en) 2000-01-31
CA2263725A1 (en) 1998-02-19
DE69737735T2 (de) 2008-01-31
IL128511A (en) 2004-06-01
NZ334147A (en) 2000-08-25
WO1998006824A1 (en) 1998-02-19
KR20000029968A (ko) 2000-05-25
JP2005118053A (ja) 2005-05-12
IL158302A0 (en) 2004-05-12
JP3754088B2 (ja) 2006-03-08
ES2285738T3 (es) 2007-11-16
HK1022496A1 (en) 2000-08-11
AU4069197A (en) 1998-03-06
US5985642A (en) 1999-11-16
BR9711067A (pt) 1999-08-17
AR008294A1 (es) 1999-12-29
UY24668A1 (es) 1998-02-02
IL158301A0 (en) 2004-05-12

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