ATE365054T1 - Diagnostisches abbildungsverfahren - Google Patents
Diagnostisches abbildungsverfahrenInfo
- Publication number
- ATE365054T1 ATE365054T1 AT04007226T AT04007226T ATE365054T1 AT E365054 T1 ATE365054 T1 AT E365054T1 AT 04007226 T AT04007226 T AT 04007226T AT 04007226 T AT04007226 T AT 04007226T AT E365054 T1 ATE365054 T1 AT E365054T1
- Authority
- AT
- Austria
- Prior art keywords
- contrast agent
- moiety
- image
- peptidic
- diagnostic imaging
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
- A61K51/1255—Granulates, agglomerates, microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
- A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
- A61K49/0089—Particulate, powder, adsorbate, bead, sphere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dispersion Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Plural Heterocyclic Compounds (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Steroid Compounds (AREA)
- Apparatus For Radiation Diagnosis (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9708265.5A GB9708265D0 (en) | 1997-04-24 | 1997-04-24 | Contrast agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE365054T1 true ATE365054T1 (de) | 2007-07-15 |
Family
ID=10811256
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04007226T ATE365054T1 (de) | 1997-04-24 | 1998-04-24 | Diagnostisches abbildungsverfahren |
| AT98917461T ATE270116T1 (de) | 1997-04-24 | 1998-04-24 | Kontrastmittel, die auf angiogenese-rezeptoren zielen |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98917461T ATE270116T1 (de) | 1997-04-24 | 1998-04-24 | Kontrastmittel, die auf angiogenese-rezeptoren zielen |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6610269B1 (de) |
| EP (2) | EP1442751B1 (de) |
| JP (1) | JP4993419B2 (de) |
| AT (2) | ATE365054T1 (de) |
| AU (1) | AU7068798A (de) |
| DE (2) | DE69837975T2 (de) |
| DK (1) | DK1442751T3 (de) |
| ES (2) | ES2287599T3 (de) |
| GB (1) | GB9708265D0 (de) |
| WO (1) | WO1998047541A1 (de) |
Families Citing this family (110)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9708265D0 (en) * | 1997-04-24 | 1997-06-18 | Nycomed Imaging As | Contrast agents |
| US6245318B1 (en) | 1997-05-27 | 2001-06-12 | Mallinckrodt Inc. | Selectively binding ultrasound contrast agents |
| US6548663B1 (en) | 1998-03-31 | 2003-04-15 | Bristol-Myers Squibb Pharma Company | Benzodiazepine vitronectin receptor antagonist pharmaceuticals |
| US6537520B1 (en) | 1998-03-31 | 2003-03-25 | Bristol-Myers Squibb Pharma Company | Pharmaceuticals for the imaging of angiogenic disorders |
| US6524553B2 (en) | 1998-03-31 | 2003-02-25 | Bristol-Myers Squibb Pharma Company | Quinolone vitronectin receptor antagonist pharmaceuticals |
| ES2241313T3 (es) | 1998-03-31 | 2005-10-16 | Bristol-Myers Squibb Pharma Company | Compuestos farmaceuticos para la formacion de imagenes de trastornos angiogenicos. |
| DE19845798A1 (de) * | 1998-09-29 | 2000-04-13 | Schering Ag | Verwendung von Neoangiogenese-Markern für Diagnose und Therapie von Tumoren, diese enthaltende Mittel, sowie Verfahren zu deren Herstellung |
| US6299860B1 (en) | 1998-10-15 | 2001-10-09 | Fluoro Probe, Inc. | Method for viewing diseased tissue located within a body cavity |
| US6284223B1 (en) | 1998-10-15 | 2001-09-04 | Fluoroprobe, Inc. | Method for viewing tumor tissue located within a body cavity |
| US6652836B2 (en) | 1998-10-15 | 2003-11-25 | Fluoroprobe, Inc. | Method for viewing tumor tissue located within a body cavity |
| US6794518B1 (en) | 1998-12-18 | 2004-09-21 | Bristol-Myers Squibb Pharma Company | Vitronectin receptor antagonist pharmaceuticals |
| NZ511677A (en) * | 1998-12-18 | 2003-10-31 | Du Pont Pharm Co | Vitronectin receptor antagonist pharmaceuticals |
| EP1140864A2 (de) | 1998-12-18 | 2001-10-10 | Du Pont Pharmaceuticals Company | Pharmazeutische zusammensetzungen, vitronectinrezeptor antagonisten enthaltend |
| US6511649B1 (en) | 1998-12-18 | 2003-01-28 | Thomas D. Harris | Vitronectin receptor antagonist pharmaceuticals |
| US6569402B1 (en) | 1998-12-18 | 2003-05-27 | Bristol-Myers Squibb Pharma Company | Vitronectin receptor antagonist pharmaceuticals |
| WO2000041726A2 (en) | 1999-01-15 | 2000-07-20 | Light Sciences Corporation | Noninvasive vascular therapy |
| US6454789B1 (en) | 1999-01-15 | 2002-09-24 | Light Science Corporation | Patient portable device for photodynamic therapy |
| US6602274B1 (en) | 1999-01-15 | 2003-08-05 | Light Sciences Corporation | Targeted transcutaneous cancer therapy |
| DE19924138A1 (de) | 1999-05-26 | 2000-11-30 | Henkel Kgaa | Lösbare Klebeverbindungen |
| GB9922173D0 (en) * | 1999-09-21 | 1999-11-17 | Zeneca Ltd | Chemical compounds |
| AU785505B2 (en) * | 1999-10-15 | 2009-02-26 | Mayo Foundation For Medical Education And Research | Cobalamin conjugates useful as imaging and therapeutic agents |
| DE19951599A1 (de) * | 1999-10-27 | 2001-05-23 | Henkel Kgaa | Verfahren zur adhesiven Trennung von Klebeverbunden |
| CA2395567A1 (en) * | 2000-01-12 | 2001-07-19 | Light Sciences Corporation | Novel treatment for eye disease |
| US6989139B2 (en) | 2000-02-15 | 2006-01-24 | Bristol-Myers Squibb Pharma Company | Matrix metalloproteinase inhibitors |
| US6656448B1 (en) * | 2000-02-15 | 2003-12-02 | Bristol-Myers Squibb Pharma Company | Matrix metalloproteinase inhibitors |
| JP5043271B2 (ja) * | 2000-04-12 | 2012-10-10 | ジーイー・ヘルスケア・アクスイェ・セルスカプ | ペプチドベースの化合物 |
| JP5078212B2 (ja) | 2000-06-02 | 2012-11-21 | ブラッコ・スイス・ソシエテ・アノニム | 内皮細胞を標的とするための化合物、それを含む組成物およびその使用方法 |
| US8263739B2 (en) | 2000-06-02 | 2012-09-11 | Bracco Suisse Sa | Compounds for targeting endothelial cells, compositions containing the same and methods for their use |
| IL153218A0 (en) | 2000-06-02 | 2003-07-06 | Univ Texas | Ethylenedicysteine (ec) -drug conjugates |
| EP1296678A2 (de) * | 2000-06-21 | 2003-04-02 | Bristol-Myers Squibb Pharma Company | Arzneimittel mit vitronektin-rezeptor-antagonistischer wirkung zur anwendung in der kombinationstherapie |
| DE10037884A1 (de) * | 2000-08-03 | 2002-02-21 | Henkel Kgaa | Verfahren zur beschleunigten Klebstoffaushärtung |
| NO20004795D0 (no) | 2000-09-26 | 2000-09-26 | Nycomed Imaging As | Peptidbaserte forbindelser |
| CN1622830A (zh) | 2001-07-10 | 2005-06-01 | 安盛药业有限公司 | 肽基化合物 |
| US7087212B2 (en) * | 2001-08-17 | 2006-08-08 | Mallinckrodt, Inc | Multicomponent assemblies having enhanced binding properties for diagnosis and therapy |
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| US7261876B2 (en) | 2002-03-01 | 2007-08-28 | Bracco International Bv | Multivalent constructs for therapeutic and diagnostic applications |
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| US10385380B2 (en) | 2014-10-02 | 2019-08-20 | The Regents Of The University Of California | Personalized protease assay to measure protease activity in neoplasms |
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| US10596259B2 (en) | 2015-05-20 | 2020-03-24 | The Regents Of The University Of California | Tumor radiosensitization with monomethyl auristatin E (MMAE) and derivatives thereof |
| WO2017147240A1 (en) | 2016-02-23 | 2017-08-31 | Tarveda Therapeutics, Inc. | Hsp90 targeted conjugates and particles and formulations thereof |
| WO2018022929A1 (en) * | 2016-07-27 | 2018-02-01 | The Trustees Of Columbia University In The City Of New York | Gel-bound compositions for radiotherapy and uses thereof |
| WO2018140730A1 (en) | 2017-01-27 | 2018-08-02 | Signalrx Pharmaceuticals, Inc. | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors |
| EP3412303A1 (de) | 2017-06-08 | 2018-12-12 | Medizinische Universität Innsbruck | Verbessertes pharmakokinetik- und cholecystokinin-2-rezeptor (cck2r)-zielverfahren für diagnose und therapie |
| EP3941580A1 (de) | 2019-03-22 | 2022-01-26 | Reflexion Pharmaceuticals, Inc. | D-peptidische verbindungen für vegf |
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| US5672334A (en) * | 1991-01-16 | 1997-09-30 | Access Pharmaceuticals, Inc. | Invivo agents comprising cationic metal chelators with acidic saccharides and glycosaminoglycans |
| MY106120A (en) * | 1988-12-05 | 1995-03-31 | Novartis Ag | Peptide derivatives. |
| ATE120374T1 (de) * | 1989-07-20 | 1995-04-15 | Sandoz Ag | Markierte polypeptidderivate. |
| US5183900A (en) | 1990-11-21 | 1993-02-02 | Galardy Richard E | Matrix metalloprotease inhibitors |
| US6107459A (en) * | 1991-02-08 | 2000-08-22 | Diatide, Inc. | Technetium-99m labeled peptides for diagnostic imaging |
| EP1306095A3 (de) | 1992-03-05 | 2003-06-25 | Board Of Regents, The University Of Texas System | Methoden und Zusammensetzungen zur Zielrichtung der Gefässe von festen Tumoren |
| US5508020A (en) * | 1992-06-05 | 1996-04-16 | Diatech, Inc. | Technetium-99M labeled peptides for imaging |
| GB9215665D0 (en) * | 1992-07-23 | 1992-09-09 | British Bio Technology | Compounds |
| CN1173991C (zh) * | 1992-11-13 | 2004-11-03 | 马克斯普朗克科学促进协会 | 作为血管内皮生长因子受体的f1k-1 |
| US5512591A (en) * | 1993-02-18 | 1996-04-30 | President And Fellows Of Harvard College | Treatments for diseases characterized by neovascularization |
| JP3670309B2 (ja) * | 1993-04-01 | 2005-07-13 | 第一製薬株式会社 | 二環性複素環化合物 |
| US5480970A (en) | 1993-12-22 | 1996-01-02 | Resolution Pharmaceuticals | Metal chelators |
| US5753230A (en) * | 1994-03-18 | 1998-05-19 | The Scripps Research Institute | Methods and compositions useful for inhibition of angiogenesis |
| US6645933B1 (en) * | 1995-08-01 | 2003-11-11 | Helsinki University Licensing Ltd. Oy | Receptor ligand VEGF-C |
| GB9502065D0 (en) * | 1995-02-02 | 1995-03-22 | Nycomed Imaging As | Contrast media |
| US6027711A (en) * | 1995-06-07 | 2000-02-22 | Rhomed Incorporated | Structurally determined metallo-constructs and applications |
| DE19522774A1 (de) * | 1995-06-27 | 1997-01-02 | Ifu Gmbh | Einrichtung zur spektroskopischen Untersuchung von Proben, die dem menschlichen Körper entnommen wurden |
| CA2242425C (en) * | 1996-02-13 | 2006-07-18 | Zeneca Limited | Quinazoline derivatives as vegf inhibitors |
| PL189698B1 (pl) * | 1996-03-12 | 2005-09-30 | Pg Txl Co | Kompozycja farmaceutyczna zawierająca lek przeciwnowotworowy i jej zastosowania |
| ES2185009T3 (es) * | 1996-04-10 | 2003-04-16 | Merck & Co Inc | Antagonistas de alfa y beta 3'. |
| GB9708265D0 (en) * | 1997-04-24 | 1997-06-18 | Nycomed Imaging As | Contrast agents |
| ES2206689T3 (es) * | 1996-10-28 | 2004-05-16 | Amersham Health As | Agentes de contraste. |
| WO1998039469A1 (en) * | 1997-03-04 | 1998-09-11 | Bio-Technology General Corp. | Isolation of tissue specific peptide ligands and their use for targeting pharmaceuticals to organs |
| CA2320339A1 (en) | 1998-02-11 | 1999-08-19 | Resolution Pharmaceuticals Inc. | Angiogenesis targeting molecules |
-
1997
- 1997-04-24 GB GBGB9708265.5A patent/GB9708265D0/en active Pending
-
1998
- 1998-04-24 EP EP04007226A patent/EP1442751B1/de not_active Expired - Lifetime
- 1998-04-24 EP EP98917461A patent/EP0977600B1/de not_active Expired - Lifetime
- 1998-04-24 ES ES04007226T patent/ES2287599T3/es not_active Expired - Lifetime
- 1998-04-24 JP JP54530798A patent/JP4993419B2/ja not_active Expired - Fee Related
- 1998-04-24 DE DE69837975T patent/DE69837975T2/de not_active Expired - Lifetime
- 1998-04-24 AT AT04007226T patent/ATE365054T1/de not_active IP Right Cessation
- 1998-04-24 WO PCT/GB1998/001197 patent/WO1998047541A1/en not_active Ceased
- 1998-04-24 DK DK04007226T patent/DK1442751T3/da active
- 1998-04-24 AT AT98917461T patent/ATE270116T1/de not_active IP Right Cessation
- 1998-04-24 DE DE69824842T patent/DE69824842T2/de not_active Expired - Lifetime
- 1998-04-24 ES ES98917461T patent/ES2224379T3/es not_active Expired - Lifetime
- 1998-04-24 AU AU70687/98A patent/AU7068798A/en not_active Abandoned
-
1999
- 1999-10-22 US US09/422,977 patent/US6610269B1/en not_active Expired - Fee Related
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2003
- 2003-06-17 US US10/462,836 patent/US7413727B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002511845A (ja) | 2002-04-16 |
| US20040009122A1 (en) | 2004-01-15 |
| DE69837975T2 (de) | 2008-02-28 |
| JP4993419B2 (ja) | 2012-08-08 |
| EP0977600B1 (de) | 2004-06-30 |
| DE69824842T2 (de) | 2005-11-17 |
| EP1442751A1 (de) | 2004-08-04 |
| US6610269B1 (en) | 2003-08-26 |
| WO1998047541A1 (en) | 1998-10-29 |
| AU7068798A (en) | 1998-11-13 |
| DK1442751T3 (da) | 2007-09-24 |
| ES2287599T3 (es) | 2007-12-16 |
| GB9708265D0 (en) | 1997-06-18 |
| DE69824842D1 (de) | 2004-08-05 |
| US7413727B2 (en) | 2008-08-19 |
| ES2224379T3 (es) | 2005-03-01 |
| ATE270116T1 (de) | 2004-07-15 |
| DE69837975D1 (de) | 2007-08-02 |
| EP1442751B1 (de) | 2007-06-20 |
| EP0977600A2 (de) | 2000-02-09 |
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