ATE365922T1 - Verfahren zur erkennung von eierstockkrebs mittels menschlichem kallikrein (hk6) - Google Patents

Verfahren zur erkennung von eierstockkrebs mittels menschlichem kallikrein (hk6)

Info

Publication number
ATE365922T1
ATE365922T1 AT01982003T AT01982003T ATE365922T1 AT E365922 T1 ATE365922 T1 AT E365922T1 AT 01982003 T AT01982003 T AT 01982003T AT 01982003 T AT01982003 T AT 01982003T AT E365922 T1 ATE365922 T1 AT E365922T1
Authority
AT
Austria
Prior art keywords
ovarian cancer
human kallikrein
detecting ovarian
binds
subject
Prior art date
Application number
AT01982003T
Other languages
English (en)
Inventor
Eleftherios Diamandis
Original Assignee
Mount Sinai Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mount Sinai Hospital Corp filed Critical Mount Sinai Hospital Corp
Application granted granted Critical
Publication of ATE365922T1 publication Critical patent/ATE365922T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57545—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the ovaries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96455—Kallikrein (3.4.21.34; 3.4.21.35)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
AT01982003T 2000-10-27 2001-10-26 Verfahren zur erkennung von eierstockkrebs mittels menschlichem kallikrein (hk6) ATE365922T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24378900P 2000-10-27 2000-10-27

Publications (1)

Publication Number Publication Date
ATE365922T1 true ATE365922T1 (de) 2007-07-15

Family

ID=22920140

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01982003T ATE365922T1 (de) 2000-10-27 2001-10-26 Verfahren zur erkennung von eierstockkrebs mittels menschlichem kallikrein (hk6)

Country Status (9)

Country Link
US (1) US20040096915A1 (de)
EP (1) EP1330652B1 (de)
JP (1) JP2004511810A (de)
AT (1) ATE365922T1 (de)
AU (1) AU2002213704A1 (de)
CA (1) CA2426286A1 (de)
DE (1) DE60129151T2 (de)
ES (1) ES2287169T3 (de)
WO (1) WO2002035232A2 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7022497B1 (en) * 1999-03-11 2006-04-04 Mt. Sinai Hospital Human kallikrein-like genes
US7199229B2 (en) * 2000-08-11 2007-04-03 Mount Sinai Hospital Kallikrein gene
JP2004512540A (ja) * 2000-11-01 2004-04-22 マウント・サイナイ・ホスピタル 卵巣癌の検出
JP2004530884A (ja) * 2001-05-25 2004-10-07 マウント・シナイ・ホスピタル Ｅｐｈｂ２のキナーゼドメインを調節する方法
WO2003034068A1 (en) * 2001-10-16 2003-04-24 Mount Sinai Hospital Localization of disorders associated with kallikreins
WO2003033731A2 (en) * 2001-10-16 2003-04-24 Mount Sinai Hospital Methods for detecting ovarian cancer
US20060159616A1 (en) * 2002-08-28 2006-07-20 Mount Sinai Hospital Methods for detecting endocrine cancer
US20060073525A1 (en) * 2002-08-28 2006-04-06 Mount Sinai Hospital Methods for detecting breast and ovarian cancer
US20060223059A1 (en) * 2002-09-26 2006-10-05 Mount Sinai Hospital Methods for detecting endocrine cancer
US20060134120A1 (en) * 2003-02-26 2006-06-22 Mount Sinai Hospital Multiple marker assay for detection of ovarian cancer
US20060141471A1 (en) * 2003-02-27 2006-06-29 Mount Sinai Hospital Assay for detection of renal cell carcinoma
CA2468651A1 (en) * 2003-06-13 2004-12-13 Eleftherios P. Diamandis Detection of neurodegenerative diseases
US20060269971A1 (en) * 2003-09-26 2006-11-30 Mount Sinai Hospital Methods for detecting prostate cancer
US7700280B2 (en) * 2003-12-31 2010-04-20 The Penn State Research Foundation Methods for assessing cisplatin resistance, disease progression, and treatment efficacy in ovarian cancer
WO2005078117A2 (en) * 2004-02-18 2005-08-25 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with kallikrein 6 (klk6)
DE102005004294A1 (de) * 2005-01-28 2006-08-03 Bayer Healthcare Ag Auswahl und Bewertung diagnostischer Tests mittels Diskordanzanalysen-Charakteristik (DAC)
EP2087152B1 (de) * 2006-10-27 2015-03-11 Walfish, Paul Endometriale biomarker
EP2271917A1 (de) * 2008-04-09 2011-01-12 Smiths Detection Inc. Mehrdimensionale spektralanalyse zur verbesserten identifikation und bestätigung von radioaktiven isotopen
US7851230B2 (en) * 2008-04-14 2010-12-14 Chang Gung Memorial Hospital Stress-induced phosphoprotein 1 as a biomarker for the detection of human ovarian cancers and endometriosis
AU2011205230A1 (en) 2010-01-13 2012-08-02 Caris Life Sciences Switzerland Holdings Gmbh Detection of gastrointestinal disorders
US9128101B2 (en) 2010-03-01 2015-09-08 Caris Life Sciences Switzerland Holdings Gmbh Biomarkers for theranostics
WO2011127219A1 (en) 2010-04-06 2011-10-13 Caris Life Sciences Luxembourg Holdings Circulating biomarkers for disease
WO2012174569A2 (en) * 2011-06-17 2012-12-20 The Board Of Trustees Of The University Of Arkansas New markers for early diagnosis of ovarian cancer, monitoring during therapy, and new therapy options during and after chematherapy
CN103675278A (zh) * 2013-11-19 2014-03-26 上海裕隆医学检验所股份有限公司 一种糖链抗原125定量检测试剂盒及其应用
WO2016061142A1 (en) 2014-10-14 2016-04-21 Novartis Ag Antibody molecules to pd-l1 and uses thereof
WO2020113237A1 (en) 2018-11-30 2020-06-04 Caris Mpi, Inc. Next-generation molecular profiling
KR20260043144A (ko) 2019-12-02 2026-03-31 캐리스 엠피아이, 아이엔씨. 범-암 백금 반응 예측기

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776427A (en) * 1992-03-05 1998-07-07 Board Of Regents, The University Of Texas System Methods for targeting the vasculature of solid tumors
IL105793A0 (en) * 1992-05-28 1993-09-22 Lilly Co Eli Protease and related dna compounds
WO1998011238A2 (en) * 1996-09-13 1998-03-19 Dana-Farber Cancer Institute Protease m, a novel serine protease
US6870027B2 (en) * 1997-03-19 2005-03-22 O'brien Timothy J. Methods for the early diagnosis of ovarian cancer
US6294344B1 (en) * 1997-03-19 2001-09-25 The Board Of Trustees Of The University Of Arkansas Methods for the early diagnosis of ovarian cancer
WO1998041656A1 (en) * 1997-03-19 1998-09-24 The Board Of Trustees Of The University Of Arkansas Compositions and method for the early diagnosis of ovarian cancer
US6268165B1 (en) * 1997-03-19 2001-07-31 The Board Of Trustees Of The University Of Arkansas Methods for the early diagnosis of ovarian cancer
US6316213B1 (en) * 1997-03-19 2001-11-13 The Board Of Trustees Of The University Of Arkansas Methods for the early diagnosis of ovarian, breast and lung cancer
CA2332131C (en) * 1998-07-02 2007-05-15 Fuso Pharmaceutical Industries, Ltd. Serine protease-specific monoclonal antibody and utilization thereof
US6942978B1 (en) * 1999-03-03 2005-09-13 The Board Of Trustees Of The University Of Arkansas Transmembrane serine protease overexpressed in ovarian carcinoma and uses thereof
US7022497B1 (en) * 1999-03-11 2006-04-04 Mt. Sinai Hospital Human kallikrein-like genes
US7935531B2 (en) * 2000-02-22 2011-05-03 Board Of Trustees Of The University Of Arkansas Methods for the early diagnosis of ovarian cancer
US7199229B2 (en) * 2000-08-11 2007-04-03 Mount Sinai Hospital Kallikrein gene
US6962793B2 (en) * 2000-10-27 2005-11-08 Mount Sinai Hospital Methods for detecting Alzheimers disease
JP2004530884A (ja) * 2001-05-25 2004-10-07 マウント・シナイ・ホスピタル Ｅｐｈｂ２のキナーゼドメインを調節する方法
WO2003033731A2 (en) * 2001-10-16 2003-04-24 Mount Sinai Hospital Methods for detecting ovarian cancer
WO2003085404A1 (en) * 2002-04-04 2003-10-16 Mount Sinai Hospital Methods for detecting ovarian cancer
US20040015745A1 (en) * 2002-07-22 2004-01-22 Finisar Corporation Scalable socketed testing tool
US20060073525A1 (en) * 2002-08-28 2006-04-06 Mount Sinai Hospital Methods for detecting breast and ovarian cancer
US20060159616A1 (en) * 2002-08-28 2006-07-20 Mount Sinai Hospital Methods for detecting endocrine cancer
US20060223059A1 (en) * 2002-09-26 2006-10-05 Mount Sinai Hospital Methods for detecting endocrine cancer
US20060134120A1 (en) * 2003-02-26 2006-06-22 Mount Sinai Hospital Multiple marker assay for detection of ovarian cancer
US20060141471A1 (en) * 2003-02-27 2006-06-29 Mount Sinai Hospital Assay for detection of renal cell carcinoma
CA2468651A1 (en) * 2003-06-13 2004-12-13 Eleftherios P. Diamandis Detection of neurodegenerative diseases
US20060269971A1 (en) * 2003-09-26 2006-11-30 Mount Sinai Hospital Methods for detecting prostate cancer

Also Published As

Publication number Publication date
ES2287169T3 (es) 2007-12-16
WO2002035232A3 (en) 2002-09-26
EP1330652B1 (de) 2007-06-27
DE60129151D1 (de) 2007-08-09
US20040096915A1 (en) 2004-05-20
CA2426286A1 (en) 2002-05-02
AU2002213704A1 (en) 2002-05-06
EP1330652A2 (de) 2003-07-30
DE60129151T2 (de) 2008-03-06
WO2002035232A2 (en) 2002-05-02
JP2004511810A (ja) 2004-04-15

Similar Documents

Publication Publication Date Title
DE60129151D1 (de) Verfahren zur erkennung von eierstockkrebs mittels menschlichem kallikrein (hk6)
WO2002037112A3 (en) Detection of ovarian cancer
EP1996940A4 (de) Nachweis von krebs anhand von erhöhten bcl-2-konzentrationen
CA2384579A1 (en) Early cancer tumor marker
DK1734368T3 (da) Annexin-autoantistoffer anvendt som markörer for lungecancer
WO2004055519A3 (en) Specific markers for pancreatic cancer
ATE289685T1 (de) Verfahren zum nachweis von karzinomen in solubilisierten zervikalen körperproben
ATE425266T1 (de) Aptamer-nanopartikelkonjugate und verwendungsverfahren zur detektion von zielanalyten
Ghazani et al. Molecular characterization of scant lung tumor cells using iron-oxide nanoparticles and micro-nuclear magnetic resonance
PT1506406E (pt) Diagnóstico de carcinoma hepatocelular
WO2010033371A3 (en) Molecular markers for lung and colorectal carcinomas
ATE267399T1 (de) Verfahren zum nachweis von komplex-gebundenem prostata-spezifischem antigen (kpsa)
WO2005040421A3 (en) Prognostic and diagnostic markers for cell proliferative disorders of the breast tissues
AU2003260457A1 (en) A method and kit for the quantitative and/or qualitative detection of components in a sample
ATE418072T1 (de) Verfahren zur diagnose von gebärmutterhalskrebs
EP1794318A4 (de) Arzneistoff-screening und molekularer diagnosetest zum frühen nachweis von kolorektalkarzinom: reagentien, verfahren und kits dafür
ATE503846T1 (de) Verfahren zur diagnose eines ovarialkarzinoms
DK2199801T3 (da) Biomarkører til tidlig påvisning af ovariecancer
CA2623653A1 (en) Use of n-myristoyltransferase on non-tumor tissue for cancer diagnosis
WO2003076896A3 (en) Use of biomarkers to detect breast cancer
WO2002063048A3 (en) Methods for predicting sensitivity of tumors to arginine deprivation
WO2002004952A3 (en) Diagnostic and therapeutic methods based on the l1 adhesion molecule for ovarian and endometrial tumors
ATE427494T1 (de) Verfahren zur quantifizierung der akt-protein- expression
WO2006089219A3 (en) Neoepitope detection of disease using protein arrays
WO2005040806A3 (en) Use of protein asc as a marker for breast cancer

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties