ATE366122T1 - Mikrowellenverfahren zur herstellung von radiomarkierten gallium komplexe - Google Patents

Mikrowellenverfahren zur herstellung von radiomarkierten gallium komplexe

Info

Publication number
ATE366122T1
ATE366122T1 AT04726564T AT04726564T ATE366122T1 AT E366122 T1 ATE366122 T1 AT E366122T1 AT 04726564 T AT04726564 T AT 04726564T AT 04726564 T AT04726564 T AT 04726564T AT E366122 T1 ATE366122 T1 AT E366122T1
Authority
AT
Austria
Prior art keywords
producing
radiom
labled
gallium complexes
microwave process
Prior art date
Application number
AT04726564T
Other languages
English (en)
Inventor
Irina Velikyan
Bengt Langstrom
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Application granted granted Critical
Publication of ATE366122T1 publication Critical patent/ATE366122T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nuclear Medicine (AREA)
  • Saccharide Compounds (AREA)
AT04726564T 2003-04-11 2004-04-08 Mikrowellenverfahren zur herstellung von radiomarkierten gallium komplexe ATE366122T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0308408.4A GB0308408D0 (en) 2003-04-11 2003-04-11 Microwave activation

Publications (1)

Publication Number Publication Date
ATE366122T1 true ATE366122T1 (de) 2007-07-15

Family

ID=9956634

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04726564T ATE366122T1 (de) 2003-04-11 2004-04-08 Mikrowellenverfahren zur herstellung von radiomarkierten gallium komplexe

Country Status (19)

Country Link
US (1) US8007766B2 (de)
EP (1) EP1620134B1 (de)
JP (1) JP4814785B2 (de)
KR (1) KR101108420B1 (de)
CN (1) CN1771058B (de)
AT (1) ATE366122T1 (de)
AU (1) AU2004228746B2 (de)
BR (1) BRPI0409101A (de)
CA (1) CA2520653C (de)
DE (1) DE602004007371T2 (de)
ES (1) ES2288255T3 (de)
GB (1) GB0308408D0 (de)
IL (1) IL170864A (de)
MX (1) MXPA05010854A (de)
NO (1) NO332419B1 (de)
PL (1) PL1620134T3 (de)
RU (1) RU2333557C2 (de)
WO (1) WO2004089425A1 (de)
ZA (1) ZA200508727B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006090232A2 (en) * 2005-02-22 2006-08-31 Ge Healthcare Limited Radiolabeled gallium complexes, methods for synthesis and use for pet imaging of egfr epxression in malignant tumors
US8926945B2 (en) 2005-10-07 2015-01-06 Guerbet Compounds comprising a biological target recognizing part, coupled to a signal part capable of complexing gallium
US8986650B2 (en) 2005-10-07 2015-03-24 Guerbet Complex folate-NOTA-Ga68
US7586102B2 (en) 2006-08-14 2009-09-08 Board Of Regents The University Of Texas System Automated system for formulating radiopharmaceuticals
WO2008026040A2 (en) * 2006-08-28 2008-03-06 Ge Healthcare Limited 68ga-labeled peptide-based radiopharmaceuticals
WO2008026051A2 (en) * 2006-08-29 2008-03-06 Ge Healthcare Limited 68ga-labelling of a free and macromolecule conjugated macrocyclic chelator at ambient temperature
JP5088928B2 (ja) * 2006-11-24 2012-12-05 新日鐵化学株式会社 ８−オキシキノリン銅の製造方法
FR2942227B1 (fr) * 2009-02-13 2011-04-15 Guerbet Sa Utilisation de tampons pour la complexation de radionucleides
GB0922492D0 (en) * 2009-12-23 2010-02-03 Hammersmith Imanet Ltd Method for obtaining 68GA
ITFI20110180A1 (it) * 2011-08-12 2013-02-13 Advanced Accelerator Applic S A Processo per la preparazione di complessi di 68ga.
CN102965502A (zh) * 2011-09-01 2013-03-13 广西大学 一种分离富集镓的固相萃取法
US11027030B2 (en) 2014-08-29 2021-06-08 Anmi S.A. Kit for radiolabelling
BE1021191B1 (fr) * 2014-08-29 2015-10-27 Anmi S.A. Kit pour radiomarquage.
GB201814291D0 (en) * 2018-09-03 2018-10-17 Univ Oslo Process for the production of gallium radionculides
US20250289832A1 (en) * 2022-04-27 2025-09-18 Nihon Medi-Physics Co., Ltd. Method for producing radioactive metal complex

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2932948C2 (de) * 1979-08-14 1982-11-18 Stiftung Deutsches Krebsforschungszentrum, 6900 Heidelberg Verfahren zur Herstellung eines Ionenaustauschers und dessen Verwendung
US5029065A (en) * 1986-12-16 1991-07-02 Ciba-Geigy Corporation Control system for a sample preparation system
US5849261A (en) * 1991-02-08 1998-12-15 Diatide, Inc. Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
RU2122431C1 (ru) * 1992-05-07 1998-11-27 Никомед Имеджинг Ас Радиоактивный иммунореагент направленного действия, композиция для получения изображения злокачественного новообразования в организме, способ получения изображения и комплексообразующий агент
DE4231622C2 (de) * 1992-09-22 1996-09-05 Bakelite Ag Verfahren zur Herstellung von Metallneutralkomplexen mit hoher Koordinationszahl und deren Verwendung
CA2154667A1 (en) * 1993-02-02 1994-08-18 Linda M. Gustavson Directed biodistribution of small molecules
EP0802919A4 (de) * 1994-06-03 1999-08-18 Mallinckrodt Medical Inc RASCH AUSGESCHIEDENES TECHNETIUM-99m-PHOSPHONAT FÜR SKELETTABBILDUNG
AU5079099A (en) * 1998-05-07 1999-11-23 Research Foundation Of The State University Of New York, The S3n radionuclide complexes
US6071490A (en) * 1998-05-07 2000-06-06 Immunomedics, Inc. Position emission tomography using gallium-68 chelates
US7011816B2 (en) * 2001-12-26 2006-03-14 Immunomedics, Inc. Labeling targeting agents with gallium-68 and gallium-67

Also Published As

Publication number Publication date
CN1771058B (zh) 2010-05-26
JP4814785B2 (ja) 2011-11-16
WO2004089425A1 (en) 2004-10-21
AU2004228746B2 (en) 2009-11-12
AU2004228746A1 (en) 2004-10-21
KR101108420B1 (ko) 2012-01-30
MXPA05010854A (es) 2005-12-14
BRPI0409101A (pt) 2006-04-04
ZA200508727B (en) 2007-09-26
GB0308408D0 (en) 2003-05-21
PL1620134T3 (pl) 2007-11-30
IL170864A (en) 2010-05-31
CN1771058A (zh) 2006-05-10
KR20060006030A (ko) 2006-01-18
US8007766B2 (en) 2011-08-30
CA2520653A1 (en) 2004-10-21
JP2006522783A (ja) 2006-10-05
NO332419B1 (no) 2012-09-17
RU2333557C2 (ru) 2008-09-10
EP1620134B1 (de) 2007-07-04
ES2288255T3 (es) 2008-01-01
NO20054615L (no) 2005-10-07
CA2520653C (en) 2012-06-05
US20070027307A1 (en) 2007-02-01
EP1620134A1 (de) 2006-02-01
RU2005130862A (ru) 2006-05-27
DE602004007371D1 (de) 2007-08-16
DE602004007371T2 (de) 2008-03-06

Similar Documents

Publication Publication Date Title
ATE366122T1 (de) Mikrowellenverfahren zur herstellung von radiomarkierten gallium komplexe
DE502004009142D1 (de) Verfahren zur herstellung substituierter 3-aryl-butyl-aminverbindungen
ATE477224T1 (de) Verwendung von miniatursierten vorrichtungen zur herstellung von radiomarkierten verbindungen
EA200602077A1 (ru) Активируемые частицы, их получение и применение
BG108497A (en) Solid-phase nucleophilic fluorination
WO2005040337A3 (en) METHODS FOR BINDING AGENTS TO β-AMYLOID PLAQUES
ATE517094T1 (de) Verfahren zur herstellung von medetomidin und seinen salzen
EA201100301A1 (ru) Daa-пиридин в качестве лиганда периферического бензодиазепинового рецептора для диагностической визуализации и фармацевтического лечения
WO2001082864A3 (en) 18f-labeled choline analogs
ATE435209T1 (de) Verfahren zur herstellung von montelukast-natrium
WO2009052970A3 (en) Compounds for use in imaging, diagnosing, and/or treatment of diseases of the central nervous system or of tumors
NO20074576L (no) Radiolabeled Gallium Complexes, Methods for Synthesis and Use For Pet Imaging of EGFR Expression in Malignant Tumors
ATE355259T1 (de) Radiofluorierungsverfahren
MX2011010295A (es) Reactivos de radiomarcado y metodos.
DE60111732D1 (de) Verfahren zur herstellung von substituierten benzimidazolverbindungen
TW200738271A (en) Methods of making radiolabeled tracers and precursors thereof
DE50106272D1 (de) Verfahren zur herstellung einer granulierbaren mischung und carnitin-magnesium-hydroxycitrat
DE502005000428D1 (de) Verfahren zur Herstellung von 1,2-Diaminocyclohexan-Platin(II)-Komplexen
WO2008026051A3 (en) 68ga-labelling of a free and macromolecule conjugated macrocyclic chelator at ambient temperature
PL365279A1 (en) Biotin-derivates and their conjugates with chelating agents
ATE419240T1 (de) Verfahren zum herstellen von 5-fluor-1,3-dialkyl- 1h-pyrazol-4-carbonsäurefluoriden
WO2023178313A3 (en) Radiopharmaceutical compositions, synthetic methods, and methods of treatment
ATE402134T1 (de) Methode zur herstellung von indan-1,3- dicarbonsäuren
ATE420844T1 (de) Neues 15o-markiertes monosaccharid und verfahren zu dessen herstellung
WO2005014479A3 (en) Process for preparing radiolabeled compounds

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties