NO20074576L - Radiolabeled Gallium Complexes, Methods for Synthesis and Use For Pet Imaging of EGFR Expression in Malignant Tumors - Google Patents

Radiolabeled Gallium Complexes, Methods for Synthesis and Use For Pet Imaging of EGFR Expression in Malignant Tumors

Info

Publication number
NO20074576L
NO20074576L NO20074576A NO20074576A NO20074576L NO 20074576 L NO20074576 L NO 20074576L NO 20074576 A NO20074576 A NO 20074576A NO 20074576 A NO20074576 A NO 20074576A NO 20074576 L NO20074576 L NO 20074576L
Authority
NO
Norway
Prior art keywords
synthesis
methods
malignant tumors
pet imaging
egfr expression
Prior art date
Application number
NO20074576A
Other languages
English (en)
Inventor
Vladimir Tolmachev
Bengt Langstrom
Asa Liljegren Sundberg
Irina Velikyan
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Publication of NO20074576L publication Critical patent/NO20074576L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Oppfinnelsen beskriver framgangsmåter for framstilling av radioaktivt merket galliumkompleks ved mikrobølgeaktivering. De resulterende galliumisotopmerkede forbindelsene kan brukes som radiofarmaka, mer spesifikt i positronemisjonstomografi (PET). Det beskrives også en framgangsmåte for å avbilde overekspresjon av EGFR i svulster med PET.
NO20074576A 2005-02-22 2007-09-10 Radiolabeled Gallium Complexes, Methods for Synthesis and Use For Pet Imaging of EGFR Expression in Malignant Tumors NO20074576L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65513905P 2005-02-22 2005-02-22
PCT/IB2006/000345 WO2006090232A2 (en) 2005-02-22 2006-02-21 Radiolabeled gallium complexes, methods for synthesis and use for pet imaging of egfr epxression in malignant tumors

Publications (1)

Publication Number Publication Date
NO20074576L true NO20074576L (no) 2007-11-20

Family

ID=36927800

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20074576A NO20074576L (no) 2005-02-22 2007-09-10 Radiolabeled Gallium Complexes, Methods for Synthesis and Use For Pet Imaging of EGFR Expression in Malignant Tumors

Country Status (12)

Country Link
US (2) US20060188441A1 (no)
EP (1) EP1850881A2 (no)
JP (1) JP2008531988A (no)
KR (1) KR20070106731A (no)
CN (1) CN101443051A (no)
AU (1) AU2006217612A1 (no)
BR (1) BRPI0608217A2 (no)
CA (1) CA2598863A1 (no)
MX (1) MX2007010116A (no)
NO (1) NO20074576L (no)
RU (1) RU2007131538A (no)
WO (1) WO2006090232A2 (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8926945B2 (en) * 2005-10-07 2015-01-06 Guerbet Compounds comprising a biological target recognizing part, coupled to a signal part capable of complexing gallium
FR2899585B1 (fr) * 2006-04-05 2012-06-15 Guerbet Sa Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium
FR2980193B1 (fr) * 2011-09-15 2014-02-14 Guerbet Sa Procede de purification de produits de contraste
JP6185262B2 (ja) * 2013-03-07 2017-08-23 日本メジフィジックス株式会社 核医学骨画像解析技術
GB201405591D0 (en) * 2014-03-28 2014-05-14 Ge Healthcare Ltd Heatseal
CN107405538B (zh) * 2015-01-30 2021-06-15 高级催化剂应用品国际有限公司 用于从来源于68Ge/68Ga发生器的洗脱物纯化Ga-68的工艺和用于所述工艺中的色谱柱
WO2021234741A1 (en) 2020-05-18 2021-11-25 C.M.S. S.P.A. Microwave device for the rapid labelling of in kit-formulated radiopharmaceuticals
JP2023157161A (ja) * 2022-04-14 2023-10-26 三菱重工航空エンジン株式会社 遮熱コーティングの施工方法及び耐熱部材
US20250289832A1 (en) * 2022-04-27 2025-09-18 Nihon Medi-Physics Co., Ltd. Method for producing radioactive metal complex

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4288424A (en) * 1979-01-15 1981-09-08 Massachusetts Institute Of Technology Generator for ionic gallium-68 based on column chromatography
US4330507A (en) * 1980-06-11 1982-05-18 New England Nuclear Corporation Method and system for generating and collecting gallium-68 using alkaline eluant
DK0436005T3 (da) * 1989-07-20 1995-07-03 Sandoz Ltd Mærkede polypeptidderivater
US5686410A (en) * 1989-07-20 1997-11-11 Novartis Ag Polypeptide derivatives
WO1993009816A1 (en) * 1991-11-14 1993-05-27 Battelle Memorial Institute Method for diagnosing and treating cancer
DE4231622C2 (de) * 1992-09-22 1996-09-05 Bakelite Ag Verfahren zur Herstellung von Metallneutralkomplexen mit hoher Koordinationszahl und deren Verwendung
US6071490A (en) * 1998-05-07 2000-06-06 Immunomedics, Inc. Position emission tomography using gallium-68 chelates
EP1389090A2 (en) * 2001-04-26 2004-02-18 Board of Regents, The University of Texas System Diagnostic imaging compositions, their methods of synthesis and use
GB0308408D0 (en) * 2003-04-11 2003-05-21 Amersham Plc Microwave activation
WO2004096254A2 (en) * 2003-05-02 2004-11-11 Xpression Antibody Therapeutics, Inc. Transferrin conjugates for tumor treatment
US20050085417A1 (en) * 2003-10-16 2005-04-21 Thomas Jefferson University Compounds and methods for diagnostic imaging and therapy

Also Published As

Publication number Publication date
WO2006090232A3 (en) 2007-04-05
CA2598863A1 (en) 2006-08-31
AU2006217612A1 (en) 2006-08-31
KR20070106731A (ko) 2007-11-05
BRPI0608217A2 (pt) 2016-10-11
MX2007010116A (es) 2007-10-12
US20060188441A1 (en) 2006-08-24
CN101443051A (zh) 2009-05-27
RU2007131538A (ru) 2009-03-27
EP1850881A2 (en) 2007-11-07
WO2006090232A2 (en) 2006-08-31
US20110117012A1 (en) 2011-05-19
JP2008531988A (ja) 2008-08-14

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Legal Events

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