ATE366260T1 - Kalzium-aktivierte kaliumkanäle mit niedriger und mittlerer leitfähigkeit und ihre verwendungen. - Google Patents

Kalzium-aktivierte kaliumkanäle mit niedriger und mittlerer leitfähigkeit und ihre verwendungen.

Info

Publication number
ATE366260T1
ATE366260T1 AT97941009T AT97941009T ATE366260T1 AT E366260 T1 ATE366260 T1 AT E366260T1 AT 97941009 T AT97941009 T AT 97941009T AT 97941009 T AT97941009 T AT 97941009T AT E366260 T1 ATE366260 T1 AT E366260T1
Authority
AT
Austria
Prior art keywords
activated potassium
calcium
low
potassium channels
potassium channel
Prior art date
Application number
AT97941009T
Other languages
English (en)
Inventor
John Adelman
James Maylie
Chris Bond
Christopher Silvia
Original Assignee
Univ Oregon Health Sciences
Ica Gen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Oregon Health Sciences, Ica Gen Inc filed Critical Univ Oregon Health Sciences
Application granted granted Critical
Publication of ATE366260T1 publication Critical patent/ATE366260T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
AT97941009T 1996-09-11 1997-09-10 Kalzium-aktivierte kaliumkanäle mit niedriger und mittlerer leitfähigkeit und ihre verwendungen. ATE366260T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2645196P 1996-09-11 1996-09-11
US4005297P 1997-03-07 1997-03-07
US4523397P 1997-04-17 1997-04-17

Publications (1)

Publication Number Publication Date
ATE366260T1 true ATE366260T1 (de) 2007-07-15

Family

ID=27362774

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97941009T ATE366260T1 (de) 1996-09-11 1997-09-10 Kalzium-aktivierte kaliumkanäle mit niedriger und mittlerer leitfähigkeit und ihre verwendungen.

Country Status (8)

Country Link
US (9) US6797486B2 (de)
EP (1) EP0948542B1 (de)
JP (5) JP4052525B2 (de)
AT (1) ATE366260T1 (de)
AU (1) AU726158B2 (de)
CA (1) CA2265485C (de)
DE (2) DE69739956D1 (de)
WO (1) WO1998011139A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69836546T2 (de) * 1997-07-15 2007-09-27 Astrazeneca Uk Ltd. Menschliches, durch kalzium aktivierbares kaliumkanalpolypeptid aus leukozyten
AU742407B2 (en) * 1997-07-15 2002-01-03 Regents Of The University Of California, The Isolated DNA encoding human calcium activated potassium channel
EP1395655A2 (de) 2000-06-06 2004-03-10 Millennium Pharmaceuticals, Inc. 52906, 33408 und 12189, mitglieder der kaliumkanalfamilie, und deren verwendungen
EP1345618B1 (de) * 2000-12-28 2005-03-23 Switch Biotech Aktiengesellschaft Chlorzoxazon zur behandlung von psoriasis
US7022480B1 (en) * 2001-10-11 2006-04-04 The Regents Of The University Of California Exons of the hSKCa3/KCNN3 gene
WO2005043973A2 (en) * 2003-10-28 2005-05-19 Janssen Pharmaceutica Nv Assay systems and methods for detecting molecules that interact with sk2 channels
EP1884774A1 (de) * 2006-08-03 2008-02-06 INSERM (Institut National de la Santé et de la Recherche Medicale) Verfahren für In-vitro-Screening von Antikrebsverbindungen als Hemmer der SK3-Aktivität und derartige Antikrebsverbindungen
CN110378549B (zh) * 2019-05-31 2023-05-23 广东工业大学 一种基于fahp-熵权法的输电杆塔鸟害等级评估方法
CN121057823A (zh) * 2023-04-10 2025-12-02 耶鲁大学 体内修饰神经元以治疗和/或预防肌萎缩性侧索硬化(als)的方法
WO2025175135A1 (en) * 2024-02-15 2025-08-21 Yale University Modifying neurons to treat or prevent parkinson's disease

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT392957B (de) 1987-08-06 1991-07-25 Technoagrar Consulting Ag Verfahren zur behandlung und entsorgung von gemengen aus feststoffen und fluessigkeiten
US6307030B1 (en) * 1988-04-15 2001-10-23 The University Of North Carolina At Chapel Hill Androgen receptor proteins, recombinant DNA molecules coding for such, and use of such compositions
CA2116280A1 (en) 1993-03-05 1994-09-06 Marcy E. Macdonald Huntingtin dna, protein and uses thereof
US5519003A (en) * 1994-02-01 1996-05-21 Board Of Trustees Of The Leland Stanford Junior University WD-40-derived peptides and uses thereof
US6277978B1 (en) * 1995-12-22 2001-08-21 University Of Utah Research Foundation KVLQT1—a long QT syndrome gene
DE69836546T2 (de) 1997-07-15 2007-09-27 Astrazeneca Uk Ltd. Menschliches, durch kalzium aktivierbares kaliumkanalpolypeptid aus leukozyten
AU742407B2 (en) * 1997-07-15 2002-01-03 Regents Of The University Of California, The Isolated DNA encoding human calcium activated potassium channel
WO1999025347A2 (en) 1997-11-14 1999-05-27 Neurosearch A/S Chemical compounds having ion channel blocking activity for the treatment of immune dysfunction

Also Published As

Publication number Publication date
US7026451B2 (en) 2006-04-11
AU4266097A (en) 1998-04-02
DE69739956D1 (de) 2010-09-16
EP0948542A4 (de) 2004-04-14
EP0948542B1 (de) 2007-07-04
US6797486B2 (en) 2004-09-28
US20030082683A1 (en) 2003-05-01
US6828420B2 (en) 2004-12-07
EP0948542A1 (de) 1999-10-13
US20020165379A1 (en) 2002-11-07
US6692937B2 (en) 2004-02-17
JP2000514310A (ja) 2000-10-31
AU726158B2 (en) 2000-11-02
US20030082684A1 (en) 2003-05-01
CA2265485A1 (en) 1998-03-19
US20030105284A1 (en) 2003-06-05
JP2006320333A (ja) 2006-11-30
US6894147B2 (en) 2005-05-17
DE69737889T2 (de) 2008-03-13
US7534869B2 (en) 2009-05-19
US6828122B2 (en) 2004-12-07
US20050214845A1 (en) 2005-09-29
JP2008092950A (ja) 2008-04-24
US20030044910A1 (en) 2003-03-06
WO1998011139A1 (en) 1998-03-19
JP2004024268A (ja) 2004-01-29
JP4052582B2 (ja) 2008-02-27
US20030040048A1 (en) 2003-02-27
JP4052525B2 (ja) 2008-02-27
US20020192757A1 (en) 2002-12-19
CA2265485C (en) 2006-08-01
DE69737889D1 (de) 2007-08-16
JP2004065264A (ja) 2004-03-04
US6987169B2 (en) 2006-01-17
US20020155531A1 (en) 2002-10-24
US6828123B2 (en) 2004-12-07

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