DE69920487D1 - Tau als marker für frühe schäden des zentralen nervensystems - Google Patents

Tau als marker für frühe schäden des zentralen nervensystems

Info

Publication number
DE69920487D1
DE69920487D1 DE69920487T DE69920487T DE69920487D1 DE 69920487 D1 DE69920487 D1 DE 69920487D1 DE 69920487 T DE69920487 T DE 69920487T DE 69920487 T DE69920487 T DE 69920487T DE 69920487 D1 DE69920487 D1 DE 69920487D1
Authority
DE
Germany
Prior art keywords
dew
marker
cns
nervous system
central nervous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69920487T
Other languages
English (en)
Other versions
DE69920487T2 (de
Inventor
Frank Hulstaert
Eugeen Vanmechelen
Hugo Vanderstichele
De Voorde Andre Van
Gool Stefaan Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujirebio Europe NV SA
Original Assignee
Innogenetics NV SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innogenetics NV SA filed Critical Innogenetics NV SA
Publication of DE69920487D1 publication Critical patent/DE69920487D1/de
Application granted granted Critical
Publication of DE69920487T2 publication Critical patent/DE69920487T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Devices That Are Associated With Refrigeration Equipment (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DE69920487T 1998-09-08 1999-09-07 Tau als marker für frühe schäden des zentralen nervensystems Expired - Lifetime DE69920487T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98870190 1998-09-08
EP98870190 1998-09-08
PCT/EP1999/006592 WO2000014546A1 (en) 1998-09-08 1999-09-07 Tau as a marker for early cns damage

Publications (2)

Publication Number Publication Date
DE69920487D1 true DE69920487D1 (de) 2004-10-28
DE69920487T2 DE69920487T2 (de) 2006-03-09

Family

ID=8237090

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69920487T Expired - Lifetime DE69920487T2 (de) 1998-09-08 1999-09-07 Tau als marker für frühe schäden des zentralen nervensystems

Country Status (11)

Country Link
EP (1) EP1112500B1 (de)
JP (1) JP4624559B2 (de)
CN (2) CN101046476B (de)
AT (1) ATE277353T1 (de)
AU (1) AU772151B2 (de)
BR (1) BR9913112A (de)
CA (1) CA2340433A1 (de)
DE (1) DE69920487T2 (de)
ES (1) ES2229817T3 (de)
HK (1) HK1040429B (de)
WO (1) WO2000014546A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4393382B2 (ja) 2002-08-14 2010-01-06 三菱化学株式会社 中枢性タウ蛋白質特異的抗体
JP5179011B2 (ja) 2002-10-09 2013-04-10 ディーエムアイ バイオサイエンシズ インコーポレイテッド 胎盤虚血および多臓器不全のモニタリング
EP2145014B1 (de) * 2007-04-05 2012-12-12 The J. David Gladstone Institutes Neuronale überanregung reduzierende agentien
US12601749B2 (en) 2008-08-11 2026-04-14 Banyan Biomarkers, Inc. Biomarker detection process and assay of neurological condition
JP5781436B2 (ja) 2008-08-11 2015-09-24 バンヤン・バイオマーカーズ・インコーポレーテッド 神経学的状態のバイオマーカー検出方法およびアッセイ
AU2010291933B2 (en) * 2009-09-14 2016-09-08 Banyan Biomarkers, Inc. Micro-RNA, autoantibody and protein markers for diagnosis of neuronal injury
RU2449287C1 (ru) * 2011-03-17 2012-04-27 Государственное образовательное учреждение высшего профессионального образования "Сибирский государственный медицинский университет" Министерства здравоохранения и социального развития Российской Федерации (ГОУ ВПО СибГМУ Минздравсоцразвития) Способ антенатального прогнозирования последствий перинатальных поражений нервной системы у детей
WO2012142301A2 (en) 2011-04-12 2012-10-18 Quanterix Corporation Methods of determining a treatment protocol for and/or a prognosis of a patients recovery from a brain injury
SG10201708959WA (en) 2012-07-03 2017-11-29 Univ Washington Antibodies to tau
KR101582387B1 (ko) * 2013-12-12 2016-01-05 서울대학교산학협력단 뇌전이암 원인종양 진단용 조성물 및 그의 용도
TWI734975B (zh) 2014-06-27 2021-08-01 美商Ｃ２Ｎ醫療診斷有限責任公司 人類化抗-tau抗體
RU2568914C1 (ru) * 2014-07-31 2015-11-20 Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский институт акушерства и педиатрии" Министерства здравоохранения Российской Федерации Способ прогнозирования перинатального поражения цнс у недоношенных новорожденных
US11078298B2 (en) 2016-10-28 2021-08-03 Banyan Biomarkers, Inc. Antibodies to ubiquitin C-terminal hydrolase L1 (UCH-L1) and glial fibrillary acidic protein (GFAP) and related methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69220503T2 (de) * 1991-10-25 1998-02-05 Innogenetics Nv Monoklonale Antikörper gegen das mikrotubulusassoziierte Protein Tau.
WO1994013795A1 (en) * 1992-12-14 1994-06-23 N.V. Innogenetics S.A. Monoclonal antibodies directed against the microtubule-associated protein tau, hybridomas secreting these antibodies, antigen recognition by these monoclonal antibodies and their applications
JPH06239899A (ja) * 1993-02-12 1994-08-30 Teijin Ltd ヒトタウ蛋白に対する抗体、並びに該抗体を利用する体液中のヒトタウ蛋白の測定方法
WO1996004309A1 (en) * 1994-07-29 1996-02-15 Innogenetics N.V. Monoclonal antibodies specific for an epitope of a particular subclass or form of phosphorylated tau, hybridomas secreting them, antigen recognition of these antibodies and their applications
US7427392B1 (en) * 1994-11-14 2008-09-23 Elan Pharmaceuticals, Inc. Methods for aiding in the diagnosis of alzheimer's disease by measuring amyloid-β peptide (x-≧41) and tau

Also Published As

Publication number Publication date
JP2002524740A (ja) 2002-08-06
ES2229817T3 (es) 2005-04-16
HK1040429B (en) 2005-08-12
CN1325491A (zh) 2001-12-05
JP4624559B2 (ja) 2011-02-02
AU772151B2 (en) 2004-04-08
EP1112500B1 (de) 2004-09-22
CA2340433A1 (en) 2000-03-16
CN101046476A (zh) 2007-10-03
BR9913112A (pt) 2001-05-08
AU5974699A (en) 2000-03-27
EP1112500A1 (de) 2001-07-04
CN101046476B (zh) 2013-04-10
HK1040429A1 (en) 2002-06-07
WO2000014546A1 (en) 2000-03-16
DE69920487T2 (de) 2006-03-09
ATE277353T1 (de) 2004-10-15

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