ATE366801T1 - Zusammensetzungen und verfahren zur trennung von zellen - Google Patents

Zusammensetzungen und verfahren zur trennung von zellen

Info

Publication number
ATE366801T1
ATE366801T1 AT03759533T AT03759533T ATE366801T1 AT E366801 T1 ATE366801 T1 AT E366801T1 AT 03759533 T AT03759533 T AT 03759533T AT 03759533 T AT03759533 T AT 03759533T AT E366801 T1 ATE366801 T1 AT E366801T1
Authority
AT
Austria
Prior art keywords
methods
compositions
separating cells
reagents
high yield
Prior art date
Application number
AT03759533T
Other languages
English (en)
Inventor
Daniel Collins
Joel Hapke
Carol Buchert
Original Assignee
Bioe Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioe Inc filed Critical Bioe Inc
Application granted granted Critical
Publication of ATE366801T1 publication Critical patent/ATE366801T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C12N5/0087—Purging against subsets of blood cells, e.g. purging alloreactive T cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/721—Dextrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C12N5/0093—Purging against cancer cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Manufacture And Refinement Of Metals (AREA)
AT03759533T 2002-09-27 2003-09-26 Zusammensetzungen und verfahren zur trennung von zellen ATE366801T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41469202P 2002-09-27 2002-09-27

Publications (1)

Publication Number Publication Date
ATE366801T1 true ATE366801T1 (de) 2007-08-15

Family

ID=32043402

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03759533T ATE366801T1 (de) 2002-09-27 2003-09-26 Zusammensetzungen und verfahren zur trennung von zellen

Country Status (13)

Country Link
US (1) US6933148B2 (de)
EP (1) EP1553832B1 (de)
JP (1) JP4344696B2 (de)
CN (1) CN100350040C (de)
AT (1) ATE366801T1 (de)
AU (1) AU2003275260B2 (de)
CA (1) CA2499826C (de)
DE (1) DE60314898T2 (de)
DK (1) DK1553832T3 (de)
IL (1) IL167624A (de)
MX (1) MXPA05003260A (de)
RU (1) RU2346039C2 (de)
WO (1) WO2004029208A2 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60238801D1 (de) * 2001-04-10 2011-02-10 Bioe Llc Zelltrennungszusammensetzungen und -verfahren
WO2004073864A2 (en) * 2003-02-13 2004-09-02 Becton, Dickinson And Company Devices for component removal during blood collection, and uses thereof
CA2563518C (en) * 2004-04-23 2014-09-02 Bioe, Inc. Multi-lineage progenitor cells
US7622108B2 (en) 2004-04-23 2009-11-24 Bioe, Inc. Multi-lineage progenitor cells
US8263404B2 (en) * 2005-04-08 2012-09-11 Medical Discovery Partners Llc Method for enriching rare cell subpopulations from blood
US7875453B2 (en) * 2006-06-14 2011-01-25 Bioe Llc Differentiation of multi-lineage progenitor cells to hepatocytes
AU2007294575B2 (en) 2006-09-08 2013-06-27 Viela Bio, Inc. Humanized anti-CD19 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
US7713688B2 (en) * 2007-01-26 2010-05-11 Bioe, Llc Methods and compositions for depleting specific cell populations from blood tissues
WO2009149382A2 (en) * 2008-06-06 2009-12-10 Baylor Research Institute Anti-cd8 antibodies block priming of cytotoxic effectors and lead to generation of regulatory cd8+t cells
CN102149472B (zh) 2008-07-21 2014-08-13 贝克顿·迪金森公司 密度相分离装置
JP5607621B2 (ja) 2008-07-21 2014-10-15 ベクトン・ディキンソン・アンド・カンパニー 密度相分離デバイス
US9333445B2 (en) 2008-07-21 2016-05-10 Becton, Dickinson And Company Density phase separation device
CN101403749B (zh) * 2008-11-17 2012-11-07 北京大学 通过葡聚糖特异性抗体辅助诊断自身免疫性疾病的试剂盒
EP2921233B1 (de) 2009-05-15 2019-10-16 Becton, Dickinson and Company Dichtephasentrennvorrichtung
DK3159001T3 (da) * 2009-09-15 2019-06-17 Univ Tokyo Hidtil ukendt fremgangsmåde til fremstilling af differentierede celler
WO2012061291A2 (en) * 2010-11-01 2012-05-10 Bioe Llc Methods and compositions for cell separation of blood tissues
EP2643694B1 (de) * 2010-11-24 2018-01-03 Litron Laboratories Ltd. Schneller in-vivo-genmutations-assay auf basis des pig-a-gens
WO2012148549A1 (en) 2011-02-25 2012-11-01 Benaroya Research Institute Detection of an immune response
CN102839152A (zh) * 2011-06-20 2012-12-26 中国科学院上海生命科学研究院 一种快速高效获得抗原特异性b细胞的方法
ES2602500T3 (es) * 2011-11-25 2017-02-21 Miltenyi Biotec Gmbh Método de separación celular
US20140295542A1 (en) * 2013-04-01 2014-10-02 Bhc Technology Holdings Llc Cell separation compositions and methods for separating and recovering therapeutic cells in blood tissue
US9694359B2 (en) 2014-11-13 2017-07-04 Becton, Dickinson And Company Mechanical separator for a biological fluid
CN108586612A (zh) * 2018-03-27 2018-09-28 深圳联合医学科技有限公司 一种适用于检测人外周血表达cd161分子亚群淋巴细胞的单克隆抗体的制备方法
RU2020122145A (ru) * 2020-07-03 2022-01-04 Петр Иванович Никитин Композиция и способ для улучшения эффективности или снижения побочных эффектов терапевтического агента, используемого для доставки нуклеиновых кислот
CN118388650B (zh) * 2024-06-28 2024-08-27 杭州赛基生物科技有限公司 一种抗CD235a单克隆抗体及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5840502A (en) * 1994-08-31 1998-11-24 Activated Cell Therapy, Inc. Methods for enriching specific cell-types by density gradient centrifugation
US6117985A (en) * 1995-06-16 2000-09-12 Stemcell Technologies Inc. Antibody compositions for preparing enriched cell preparations
US5877299A (en) * 1995-06-16 1999-03-02 Stemcell Technologies Inc. Methods for preparing enriched human hematopoietic cell preparations
US6146628A (en) * 1995-07-11 2000-11-14 Regents Of The University Of Minnesota And Rutgers Biotherapeutic agents comprising recombinant PAP and PAP mutants
CA2279474C (en) * 1998-07-31 2011-01-04 Stemcell Technologies Inc. Novel antibody composition for debulking blood and bone marrow samples from cml patients
US6153113A (en) * 1999-02-22 2000-11-28 Cobe Laboratories, Inc. Method for using ligands in particle separation
CA2375115C (en) * 1999-05-28 2011-05-24 Stemcell Technologies Inc. Method for separating cells using immunorosettes
DE60238801D1 (de) * 2001-04-10 2011-02-10 Bioe Llc Zelltrennungszusammensetzungen und -verfahren

Also Published As

Publication number Publication date
AU2003275260A1 (en) 2004-04-19
IL167624A (en) 2009-12-24
DK1553832T3 (da) 2007-10-01
US20040062766A1 (en) 2004-04-01
EP1553832A2 (de) 2005-07-20
EP1553832A4 (de) 2006-02-01
MXPA05003260A (es) 2005-09-12
AU2003275260B2 (en) 2008-01-24
CN100350040C (zh) 2007-11-21
WO2004029208A3 (en) 2005-04-14
CA2499826C (en) 2015-03-24
CN1735346A (zh) 2006-02-15
RU2005112731A (ru) 2006-01-20
RU2346039C2 (ru) 2009-02-10
EP1553832B1 (de) 2007-07-11
CA2499826A1 (en) 2004-04-08
JP2006500932A (ja) 2006-01-12
JP4344696B2 (ja) 2009-10-14
US6933148B2 (en) 2005-08-23
DE60314898T2 (de) 2008-03-13
DE60314898D1 (de) 2007-08-23
WO2004029208A2 (en) 2004-04-08

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