ATE367438T1 - Verfahren zur steigerung der expression von menschlichen tnf-rezeptor - Google Patents

Verfahren zur steigerung der expression von menschlichen tnf-rezeptor

Info

Publication number
ATE367438T1
ATE367438T1 AT02777356T AT02777356T ATE367438T1 AT E367438 T1 ATE367438 T1 AT E367438T1 AT 02777356 T AT02777356 T AT 02777356T AT 02777356 T AT02777356 T AT 02777356T AT E367438 T1 ATE367438 T1 AT E367438T1
Authority
AT
Austria
Prior art keywords
amino acid
proline
tnf receptor
receptor expression
human tnf
Prior art date
Application number
AT02777356T
Other languages
English (en)
Inventor
William Brondyk
Xuliang Jiang
Rene Schweickhardt
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Application granted granted Critical
Publication of ATE367438T1 publication Critical patent/ATE367438T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/144—Tumor necrosis factor

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
AT02777356T 2001-11-30 2002-11-21 Verfahren zur steigerung der expression von menschlichen tnf-rezeptor ATE367438T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34064801P 2001-11-30 2001-11-30

Publications (1)

Publication Number Publication Date
ATE367438T1 true ATE367438T1 (de) 2007-08-15

Family

ID=23334343

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02777356T ATE367438T1 (de) 2001-11-30 2002-11-21 Verfahren zur steigerung der expression von menschlichen tnf-rezeptor

Country Status (12)

Country Link
US (2) US7258997B2 (de)
EP (1) EP1448772B1 (de)
JP (1) JP2005535281A (de)
AT (1) ATE367438T1 (de)
AU (1) AU2002338947B2 (de)
CA (1) CA2466298A1 (de)
DE (1) DE60221273D1 (de)
DK (1) DK1448772T3 (de)
ES (1) ES2290337T3 (de)
IL (1) IL162133A0 (de)
PT (1) PT1448772E (de)
WO (1) WO2003046160A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7258997B2 (en) * 2001-11-30 2007-08-21 Applied Research Systems Ars Holding N.V. Methods of increasing protein expression levels
JP2008504009A (ja) * 2003-12-23 2008-02-14 アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ 腫瘍壊死因子結合蛋白質を生産する方法
US8722348B2 (en) 2008-05-28 2014-05-13 Wayne State University Method and composition for a protein transduction technology and its applications
PL2705143T3 (pl) 2011-05-02 2021-07-19 Wayne State University Technologia indukowanych białkiem komórek pluripotencjalnych, jej zastosowania
ES2896021T3 (es) 2013-10-25 2022-02-23 Univ Wayne State Proteína de reprogramación modificada para uso en el tratamiento de un cáncer
KR20220056847A (ko) * 2019-06-21 2022-05-06 커날 바이오로직스, 인크. 조작된 종양선택적 단백질 발현
KR20220153011A (ko) * 2020-02-03 2022-11-17 프레마스 바이오테크 프라이빗 리미티드 난발현 단백질(dte-p)의 발현을 위한 재조합 발현 플랫폼, 구축물 및 방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE289350T1 (de) 1989-04-21 2005-03-15 Amgen Inc Tnf-rezeptor, tnf bindende proteine und dafür kodierende dnas
AU3073692A (en) * 1991-11-25 1993-06-28 Richardson-Vicks Inc. Compositions for regulating skin wrinkles and/or skin atrophy
IL107268A0 (en) 1993-10-12 1994-01-25 Yeda Res & Dev Molecules influencing the shedding of the tnf receptor, their preparation and their use
US7074901B2 (en) * 2001-05-25 2006-07-11 Serono Genetics Institute S.A. Isolated human vCOL16A1 polypeptide and fragments thereof
US7258997B2 (en) * 2001-11-30 2007-08-21 Applied Research Systems Ars Holding N.V. Methods of increasing protein expression levels

Also Published As

Publication number Publication date
DK1448772T3 (da) 2007-11-19
US20050074840A1 (en) 2005-04-07
AU2002338947B2 (en) 2007-09-13
PT1448772E (pt) 2007-10-02
US20080014635A1 (en) 2008-01-17
IL162133A0 (en) 2005-11-20
DE60221273D1 (de) 2007-08-30
AU2002338947A1 (en) 2003-06-10
EP1448772A2 (de) 2004-08-25
WO2003046160A3 (en) 2003-07-31
ES2290337T3 (es) 2008-02-16
EP1448772B1 (de) 2007-07-18
WO2003046160A2 (en) 2003-06-05
JP2005535281A (ja) 2005-11-24
US7258997B2 (en) 2007-08-21
CA2466298A1 (en) 2003-06-05

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