ATE533845T1 - Eukaryotische signalsequenzen zur polypeptid- expression und polypeptid-anzeigebibliotheken - Google Patents

Eukaryotische signalsequenzen zur polypeptid- expression und polypeptid-anzeigebibliotheken

Info

Publication number
ATE533845T1
ATE533845T1 AT08163005T AT08163005T ATE533845T1 AT E533845 T1 ATE533845 T1 AT E533845T1 AT 08163005 T AT08163005 T AT 08163005T AT 08163005 T AT08163005 T AT 08163005T AT E533845 T1 ATE533845 T1 AT E533845T1
Authority
AT
Austria
Prior art keywords
polypeptide
signaling sequences
expression
libraries
eukaryotic signaling
Prior art date
Application number
AT08163005T
Other languages
English (en)
Inventor
Jeff Gray
Joe Buechler
Uday Veeramallu
Original Assignee
Xoma Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xoma Technology Ltd filed Critical Xoma Technology Ltd
Application granted granted Critical
Publication of ATE533845T1 publication Critical patent/ATE533845T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT08163005T 2002-02-13 2003-02-13 Eukaryotische signalsequenzen zur polypeptid- expression und polypeptid-anzeigebibliotheken ATE533845T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/076,802 US7094579B2 (en) 2002-02-13 2002-02-13 Eukaryotic signal sequences for prokaryotic expression

Publications (1)

Publication Number Publication Date
ATE533845T1 true ATE533845T1 (de) 2011-12-15

Family

ID=27732544

Family Applications (2)

Application Number Title Priority Date Filing Date
AT03739833T ATE406439T1 (de) 2002-02-13 2003-02-13 Eukaryontische signalsequenzen für polypeptid- expressions- und polypeptid- präsentationsbibliotheken
AT08163005T ATE533845T1 (de) 2002-02-13 2003-02-13 Eukaryotische signalsequenzen zur polypeptid- expression und polypeptid-anzeigebibliotheken

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT03739833T ATE406439T1 (de) 2002-02-13 2003-02-13 Eukaryontische signalsequenzen für polypeptid- expressions- und polypeptid- präsentationsbibliotheken

Country Status (9)

Country Link
US (5) US7094579B2 (de)
EP (2) EP1481059B1 (de)
JP (2) JP4303596B2 (de)
AT (2) ATE406439T1 (de)
AU (1) AU2003225578B2 (de)
CA (1) CA2475929C (de)
DE (1) DE60323210D1 (de)
DK (2) DK1481059T3 (de)
WO (1) WO2003068956A1 (de)

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AU2012212047A1 (en) 2011-02-03 2013-08-22 Xoma Technology Ltd. Methods and materials for enhancing functional protein expression in bacteria
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MX2018004875A (es) 2015-10-22 2018-08-01 Juno Therapeutics Gmbh Metodos para cultivar celulas y kits y aparatos para ello.
EP3365453A2 (de) 2015-10-22 2018-08-29 Juno Therapeutics GmbH Verfahren, kits, mittel und vorrichtungen zur transduktion
US10954500B2 (en) 2015-10-23 2021-03-23 Fred Hutchinson Cancer Research Center Methods to create chemically-induced dimerizing protein systems for regulation of cellular events
CN105734061B (zh) * 2016-03-25 2019-07-23 中国农业科学院生物技术研究所 从毕赤酵母中分离的鼠李糖诱导型启动子及其应用
JP7339160B2 (ja) 2017-04-27 2023-09-05 ジュノ セラピューティクス ゲーエムベーハー オリゴマー粒子試薬およびその使用方法
EP3444269A1 (de) 2017-08-17 2019-02-20 National Research Council of Canada Systeme und methoden für die produktion von diphteria-giftstoff-polypeptiden
IL275239B2 (en) 2017-12-11 2026-03-01 Abalone Bio Inc Yeast presentation of proteins in the subplasmic space
SG11202104355SA (en) 2018-10-31 2021-05-28 Juno Therapeutics Gmbh Methods for selection and stimulation of cells and apparatus for same
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
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MX2022010467A (es) * 2020-02-25 2022-12-15 Momenta Pharmaceuticals Inc Enzimas para la sialilación de glicanos.
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
US12537071B1 (en) 2020-07-22 2026-01-27 David Gordon Bermudes Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins
CN116284288A (zh) * 2023-02-01 2023-06-23 深圳大学 莱茵衣藻分泌导肽和转基因莱茵衣藻及其构建方法与应用

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Also Published As

Publication number Publication date
DK1481059T3 (da) 2009-01-12
AU2003225578A1 (en) 2003-09-04
US8476040B2 (en) 2013-07-02
CA2475929A1 (en) 2003-08-21
JP2009131286A (ja) 2009-06-18
US7094579B2 (en) 2006-08-22
US20030228660A1 (en) 2003-12-11
US20030162249A1 (en) 2003-08-28
AU2003225578B2 (en) 2008-04-03
CA2475929C (en) 2013-01-15
US20080214411A1 (en) 2008-09-04
EP1481059A1 (de) 2004-12-01
EP2060628B1 (de) 2011-11-16
US20110224102A1 (en) 2011-09-15
JP4303596B2 (ja) 2009-07-29
JP5190963B2 (ja) 2013-04-24
US7396661B2 (en) 2008-07-08
US7977068B2 (en) 2011-07-12
ATE406439T1 (de) 2008-09-15
US7972811B2 (en) 2011-07-05
US20100009857A1 (en) 2010-01-14
DE60323210D1 (en) 2008-10-09
DK2060628T3 (da) 2012-01-23
JP2005517407A (ja) 2005-06-16
EP1481059A4 (de) 2006-02-01
EP2060628A1 (de) 2009-05-20
EP1481059B1 (de) 2008-08-27
WO2003068956A1 (en) 2003-08-21

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