ATE369119T1 - Osmotisches abgabesystem mit schubmotor früher nullter ordnung mit einem osmotischen mittel, das in dem flüssigen vehikel dispergiert ist - Google Patents

Osmotisches abgabesystem mit schubmotor früher nullter ordnung mit einem osmotischen mittel, das in dem flüssigen vehikel dispergiert ist

Info

Publication number
ATE369119T1
ATE369119T1 AT03760392T AT03760392T ATE369119T1 AT E369119 T1 ATE369119 T1 AT E369119T1 AT 03760392 T AT03760392 T AT 03760392T AT 03760392 T AT03760392 T AT 03760392T AT E369119 T1 ATE369119 T1 AT E369119T1
Authority
AT
Austria
Prior art keywords
osmotic
delivery system
liquid vehicle
zero order
agent dispersed
Prior art date
Application number
AT03760392T
Other languages
English (en)
Inventor
Pamela Fereira
Stephen Berry
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ATE369119T1 publication Critical patent/ATE369119T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT03760392T 2002-06-17 2003-06-17 Osmotisches abgabesystem mit schubmotor früher nullter ordnung mit einem osmotischen mittel, das in dem flüssigen vehikel dispergiert ist ATE369119T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38950902P 2002-06-17 2002-06-17

Publications (1)

Publication Number Publication Date
ATE369119T1 true ATE369119T1 (de) 2007-08-15

Family

ID=29736646

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03760392T ATE369119T1 (de) 2002-06-17 2003-06-17 Osmotisches abgabesystem mit schubmotor früher nullter ordnung mit einem osmotischen mittel, das in dem flüssigen vehikel dispergiert ist

Country Status (19)

Country Link
US (2) US7074423B2 (de)
EP (1) EP1536767B1 (de)
JP (1) JP2005533782A (de)
KR (1) KR20050026402A (de)
CN (1) CN1668279A (de)
AR (1) AR039696A1 (de)
AT (1) ATE369119T1 (de)
AU (1) AU2003251535B2 (de)
BR (1) BR0311897A (de)
CA (1) CA2489325C (de)
DE (1) DE60315474T2 (de)
IL (1) IL165697A (de)
MX (1) MXPA04012976A (de)
MY (1) MY135711A (de)
NO (1) NO20050047L (de)
NZ (1) NZ537136A (de)
TW (1) TW200420306A (de)
WO (1) WO2003105803A1 (de)
ZA (1) ZA200500343B (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY125870A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system flow modulator apparatus and method
US7919109B2 (en) 1999-02-08 2011-04-05 Intarcia Therapeutics, Inc. Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles
US7258869B1 (en) * 1999-02-08 2007-08-21 Alza Corporation Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle
US7163688B2 (en) * 2001-06-22 2007-01-16 Alza Corporation Osmotic implant with membrane and membrane retention means
WO2003105803A1 (en) * 2002-06-17 2003-12-24 Alza Corporation Osmotic delivery system with early zero order push power engine comprising an osmotic agent dispersed in the fluid vehicle
MXPA05006604A (es) * 2002-12-19 2006-05-25 Alza Corp Geles de una sola fase, no acuosos, estables, y formulaciones de los mismos para el suministro desde un aparato implantable.
US7731947B2 (en) * 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
DE602004012081T2 (de) * 2003-03-31 2009-03-19 Intarcia Therapeutics, Inc., Emeryville Osmotische pumpe mit mitteln zum ableiten des innendrucks
TW200509999A (en) * 2003-03-31 2005-03-16 Alza Corp Osmotic delivery system and method for decreasing start-up times for osmotic delivery systems
PL379736A1 (pl) * 2003-11-06 2006-11-13 Alza Corporation Modułowy reduktor prędkości wchłaniania do stosowania z wszczepianą pompą osmotyczną
US20050266087A1 (en) * 2004-05-25 2005-12-01 Gunjan Junnarkar Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
US7655254B2 (en) * 2005-02-03 2010-02-02 Intarcia Therapeutics, Inc. Implantable device for continuous delivery of interferon
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US7959938B2 (en) * 2005-03-15 2011-06-14 Intarcia Therapeutics, Inc. Polyoxaester suspending vehicles for use with implantable delivery systems
KR101106510B1 (ko) 2006-05-30 2012-01-20 인타르시아 세라퓨틱스 인코포레이티드 투피스, 내부채널 삼투압 전달 시스템 유동 조절기
EP2359808B1 (de) * 2006-08-09 2013-05-22 Intarcia Therapeutics, Inc Osmotisches Verabreichungssystem mit Kolbenanordnung
WO2008133908A2 (en) * 2007-04-23 2008-11-06 Intarcia Therapeutics, Inc. Suspension formulations of insulinotropic peptides and uses thereof
CA2726861C (en) * 2008-02-13 2014-05-27 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
US20090259112A1 (en) * 2008-04-09 2009-10-15 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Sensors
US20090259217A1 (en) * 2008-04-09 2009-10-15 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems associated with delivery of one or more agents to an individual
CN102281865B (zh) * 2008-10-15 2017-04-05 精达制药公司 高浓缩药物颗粒、制剂、混悬剂及其应用
RU2547990C2 (ru) 2009-09-28 2015-04-10 Интарсия Терапьютикс, Инк. Быстрое достижение и/или прекращение существенной стабильной доставки лекарственного средства
CN101897995B (zh) * 2010-07-09 2012-12-19 深圳市北科生物科技有限公司 一种可植入的披膜三维载体及其制备方法
JP2013540464A (ja) 2010-08-30 2013-11-07 サイナシス コーポレーション 副鼻腔開口部を拡張するため、および副鼻腔炎を治療するためのデバイスおよび方法
US8518440B2 (en) 2010-12-21 2013-08-27 Confluent Surgical, Inc. Biodegradable osmotic pump implant for drug delivery
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US8986337B2 (en) 2012-02-24 2015-03-24 Elwha Llc Devices, systems, and methods to control stomach volume
EP2819740A4 (de) 2012-02-29 2015-11-25 Sinusys Corp Vorrichtungen und verfahren zur dilatation einer paranasalen sinusöffnung und zur behandlung von sinusitis
US9687263B2 (en) 2013-05-30 2017-06-27 SinuSys Corporation Devices and methods for inserting a sinus dilator
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
RU2730996C2 (ru) 2015-06-03 2020-08-26 Интарсия Терапьютикс, Инк. Системы установки и извлечения имплантата
KR102574993B1 (ko) 2016-05-16 2023-09-06 인타르시아 세라퓨틱스 인코포레이티드 글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
JP7286542B2 (ja) 2017-01-03 2023-06-05 インターシア セラピューティクス,インコーポレイティド Glp-1受容体アゴニストの持続的投与及び薬物の同時投与を含む方法
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly
CN110613872A (zh) * 2019-10-31 2019-12-27 厦门大学嘉庚学院 一种防止血液凝固的留置针辅助装置及其工作方法

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4034756A (en) * 1971-01-13 1977-07-12 Alza Corporation Osmotically driven fluid dispenser
JPS5854962A (ja) * 1981-09-27 1983-04-01 テルモ株式会社 注出ポンプ
US4783337A (en) * 1983-05-11 1988-11-08 Alza Corporation Osmotic system comprising plurality of members for dispensing drug
US4851228A (en) * 1984-06-20 1989-07-25 Merck & Co., Inc. Multiparticulate controlled porosity osmotic
US4624847A (en) * 1985-04-22 1986-11-25 Alza Corporation Drug delivery device for programmed delivery of beneficial drug
US4609374A (en) * 1985-04-22 1986-09-02 Alza Corporation Osmotic device comprising means for governing initial time of agent release therefrom
US5938654A (en) * 1987-06-25 1999-08-17 Alza Corporation Osmotic device for delayed delivery of agent
US5023088A (en) * 1987-06-25 1991-06-11 Alza Corporation Multi-unit delivery system
US4874388A (en) * 1987-06-25 1989-10-17 Alza Corporation Multi-layer delivery system
US4886668A (en) * 1987-09-24 1989-12-12 Merck & Co., Inc. Multiparticulate controlled porosity osmotic pump
US5223266A (en) 1990-01-24 1993-06-29 Alza Corporation Long-term delivery device with early startup
US5324280A (en) * 1990-04-02 1994-06-28 Alza Corporation Osmotic dosage system for delivering a formulation comprising liquid carrier and drug
EP0607321A1 (de) * 1991-10-10 1994-07-27 Alza Corporation Osmotische wirkstoffabgabevorrichtung mit hydrophabem wandmaterial
US5318780A (en) * 1991-10-30 1994-06-07 Mediventures Inc. Medical uses of in situ formed gels
US5209746A (en) * 1992-02-18 1993-05-11 Alza Corporation Osmotically driven delivery devices with pulsatile effect
US5639477A (en) * 1993-06-23 1997-06-17 Alza Corporation Ruminal drug delivery device
US5388883A (en) * 1993-11-18 1995-02-14 Yang; Shyue-Jong A. Sun shield cover
US5595759A (en) * 1994-11-10 1997-01-21 Alza Corporation Process for providing therapeutic composition
US5904935A (en) * 1995-06-07 1999-05-18 Alza Corporation Peptide/protein suspending formulations
NZ331186A (en) * 1996-02-02 2000-04-28 Alza Corp Osmotically driven sustained delivery drug delivery capsule
US6132420A (en) 1996-02-02 2000-10-17 Alza Corporation Osmotic delivery system and method for enhancing start-up and performance of osmotic delivery systems
US5932547A (en) * 1996-07-03 1999-08-03 Alza Corporation Non-aqueous polar aprotic peptide formulations
WO1998020930A1 (en) * 1996-11-15 1998-05-22 Alza Corporation Osmotic delivery system and method for enhancing start-up and performance of osmotic delivery systems
ZA981610B (en) * 1997-03-24 1999-08-26 Alza Corp Self adjustable exit port.
MY125870A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system flow modulator apparatus and method
MY125849A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system, osmotic delivery system semipermeable body assembly, and method for controlling delivery rate of beneficial agents from osmotic delivery systems
AU1623099A (en) * 1997-12-22 1999-07-12 Alza Corporation Rate controlling membranes for controlled drug delivery devices
WO1999033446A1 (en) * 1997-12-29 1999-07-08 Alza Corporation Osmotic delivery system with membrane plug retention mechanism
KR100568917B1 (ko) * 1997-12-30 2006-04-07 알자 코포레이션 멤브레인 플러그를 갖는 익제 전달장치
EP1140014B1 (de) * 1998-12-31 2003-03-19 Alza Corporation Osmotisches verabreichungsystem mit raumsparenden kolben
US7258869B1 (en) * 1999-02-08 2007-08-21 Alza Corporation Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle
ES2248156T3 (es) * 1999-12-21 2006-03-16 Alza Corporation Valvula para dispositivos osmoticos.
US7163688B2 (en) * 2001-06-22 2007-01-16 Alza Corporation Osmotic implant with membrane and membrane retention means
AR026386A1 (es) * 2001-10-24 2003-02-12 Massara Julio Eduardo Un dispositivo intravaginal que contiene progesterona, util como inductor de celo en bovinos productores de carne y leche, y el procedimiento paraprepararlo
WO2003105803A1 (en) * 2002-06-17 2003-12-24 Alza Corporation Osmotic delivery system with early zero order push power engine comprising an osmotic agent dispersed in the fluid vehicle
US7014636B2 (en) * 2002-11-21 2006-03-21 Alza Corporation Osmotic delivery device having a two-way valve and a dynamically self-adjusting flow channel
US7731947B2 (en) * 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
MXPA05006604A (es) * 2002-12-19 2006-05-25 Alza Corp Geles de una sola fase, no acuosos, estables, y formulaciones de los mismos para el suministro desde un aparato implantable.
CN1767815A (zh) * 2003-03-31 2006-05-03 阿尔萨公司 非水单相载体和使用这类载体的制剂
DE602004012081T2 (de) * 2003-03-31 2009-03-19 Intarcia Therapeutics, Inc., Emeryville Osmotische pumpe mit mitteln zum ableiten des innendrucks
US8377459B2 (en) * 2003-07-09 2013-02-19 The Procter & Gamble Company Composition for wet wipes that enhances the efficacy of cleansing while being gentle to the skin
US20050175701A1 (en) * 2004-02-10 2005-08-11 Alza Corporation Capillary moderator for osmotic delivery system
US20050266087A1 (en) * 2004-05-25 2005-12-01 Gunjan Junnarkar Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium
WO2006083761A2 (en) * 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US20060216242A1 (en) * 2005-02-03 2006-09-28 Rohloff Catherine M Suspending vehicles and pharmaceutical suspensions for drug dosage forms
US7959938B2 (en) * 2005-03-15 2011-06-14 Intarcia Therapeutics, Inc. Polyoxaester suspending vehicles for use with implantable delivery systems
US20070027105A1 (en) * 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
KR101106510B1 (ko) * 2006-05-30 2012-01-20 인타르시아 세라퓨틱스 인코포레이티드 투피스, 내부채널 삼투압 전달 시스템 유동 조절기

Also Published As

Publication number Publication date
WO2003105803A1 (en) 2003-12-24
IL165697A (en) 2010-04-29
AR039696A1 (es) 2005-03-09
JP2005533782A (ja) 2005-11-10
ZA200500343B (en) 2006-03-29
KR20050026402A (ko) 2005-03-15
US20040097906A1 (en) 2004-05-20
TW200420306A (en) 2004-10-16
CA2489325C (en) 2010-08-10
US7074423B2 (en) 2006-07-11
CA2489325A1 (en) 2003-12-24
EP1536767B1 (de) 2007-08-08
MY135711A (en) 2008-06-30
NO20050047L (no) 2005-01-05
NZ537136A (en) 2007-07-27
AU2003251535A1 (en) 2003-12-31
CN1668279A (zh) 2005-09-14
US20060184158A1 (en) 2006-08-17
BR0311897A (pt) 2005-04-05
DE60315474D1 (de) 2007-09-20
EP1536767A1 (de) 2005-06-08
DE60315474T2 (de) 2008-04-24
MXPA04012976A (es) 2005-05-16
AU2003251535B2 (en) 2008-12-18
IL165697A0 (en) 2006-01-15

Similar Documents

Publication Publication Date Title
ATE369119T1 (de) Osmotisches abgabesystem mit schubmotor früher nullter ordnung mit einem osmotischen mittel, das in dem flüssigen vehikel dispergiert ist
DE60000294D1 (de) System und Vorrichtung mit mehreren Leistungsquellen, Motorantriebsvorrichtung und Hybridfahrzeug mit diesem System
DE69725666D1 (de) Dem benutzer zugeneigtes multimediapräsentationssystem für mehrere präsentationsartikel, welche jeder als ein agent wirken
DE60305013D1 (de) Herunterklappbare, im boden verstaubare kraftfahrzeugsitzanordnung
DE60300351D1 (de) Insassenschutzvorrichtung im Fahrzeugsitz
DE502004008759D1 (de) Fahrzeugsitz, insbesondere Kraftfahrzeugsitz
DE50208947D1 (de) Motor-Pumpen-Aggregat, insbesondere für eine Kraftfahrzeug-Bremsvorrichtung
DE60329616D1 (de) Im boden verstaubare kraftfahrzeugsitzanordnung
AP2006003481A0 (en) 2-Substituted phenyl-5, 7- dihydrocarbyl-3, 7- di hydropyrrolo Ä2,3-dÜ pyrimidin-4- one derivatives,the preparation and the pharmaceutical use thereo f.
BR0209307B1 (pt) aparelho para uso em bombas.
ES2294913B2 (es) Sistema de mensajeria y metodo para el mismo.
AU2003260416A1 (en) Method and device for taking off extrusion products, in particular for aligning the caterpillar take-off unit with the extrusion axis
IT1311333B1 (it) Sistema di controllo del clima nell'abitacolo di un autoveicolo.
IT232322Y1 (it) Dispositivo di tenuta per cuscinetti volventi, in particolare per mozzi ruota di veicoli.
ES1054232Y (es) Estructura movil para la lona de cubricion en vehiculos de transporte.
Marcus et al. Zn speciation in two Fe-Mn banded systems
AU2003281289A1 (en) Regenerative fluid pump and stator for the same
IT1318304B1 (it) Dispositivo di segnalazione di sosta di emergenza per autoveicoli, inparticolare triangolo di segnalazione.
ES1052223Y (es) Sistema de seguridad en el arranque de vehiculos motorizados.
李蓉 Rebellious Spirit in Shelley’s Poetry
IT234058Y1 (it) Irroratore girevole per vasche di vinificazione, in particolare per la cosiddetta vinificazione in rosso.
TR199900376A3 (tr) Motorlu araçlarda yangin söndürme sistemi.
ITRM20030254A0 (it) Complesso pneumatico-cerchione con sistema di sicurezza in caso di foratura.
ITRM20030042V0 (it) Sistema di aste portaoggetti estraibili ed incorporate a scomparsa nel tetto di un veicolo.
ITTO20050844A1 (it) Sistema di frenatura con dispositivo di frenata a pompe idrauliche collegate assialmente sulle quattro ruote per autoveicoli e autocarri

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties