ATE369354T1 - Isochinolin-aroylpyrrole für die behandlung von krankheiten des zentralnervensystems - Google Patents

Isochinolin-aroylpyrrole für die behandlung von krankheiten des zentralnervensystems

Info

Publication number
ATE369354T1
ATE369354T1 AT01989198T AT01989198T ATE369354T1 AT E369354 T1 ATE369354 T1 AT E369354T1 AT 01989198 T AT01989198 T AT 01989198T AT 01989198 T AT01989198 T AT 01989198T AT E369354 T1 ATE369354 T1 AT E369354T1
Authority
AT
Austria
Prior art keywords
treatment
nervous system
central nervous
aroylpyrroles
isoquinoline
Prior art date
Application number
AT01989198T
Other languages
English (en)
Inventor
John Carson
Philip Pitis
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of ATE369354T1 publication Critical patent/ATE369354T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT01989198T 2000-12-20 2001-12-11 Isochinolin-aroylpyrrole für die behandlung von krankheiten des zentralnervensystems ATE369354T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25686500P 2000-12-20 2000-12-20

Publications (1)

Publication Number Publication Date
ATE369354T1 true ATE369354T1 (de) 2007-08-15

Family

ID=22973908

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01989198T ATE369354T1 (de) 2000-12-20 2001-12-11 Isochinolin-aroylpyrrole für die behandlung von krankheiten des zentralnervensystems

Country Status (12)

Country Link
US (1) US6492387B2 (de)
EP (1) EP1351950B1 (de)
JP (1) JP2004517893A (de)
AT (1) ATE369354T1 (de)
AU (1) AU2002243310A1 (de)
CA (1) CA2432776A1 (de)
CY (1) CY1106922T1 (de)
DE (1) DE60129846T2 (de)
DK (1) DK1351950T3 (de)
ES (1) ES2291373T3 (de)
PT (1) PT1351950E (de)
WO (1) WO2002057253A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0109957D0 (en) * 2001-04-24 2001-06-13 Martin Sanders T A Vensha Inno Binding system
DE10261131A1 (de) 2002-12-20 2004-07-01 Grünenthal GmbH Substituierte 5-Aminomethyl-1H-pyrrol-2-carbonsäureamide

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5332736A (en) * 1993-11-01 1994-07-26 Ortho Pharmaceutical Corporation Anti-convulsant aroyl aminoacylpyrroles
US5760007A (en) 1997-07-16 1998-06-02 Ortho Pharmaceutical Corporation Anticonvulsant derivatives useful in treating neuropathic pain
ES2209843T3 (es) 1999-02-18 2004-07-01 Ortho-Mcneil Pharmaceutical, Inc. Aroil aminoacil pirroles para uso en el tratamiento del dolor neuropatico.
WO2002002521A2 (en) 2000-06-30 2002-01-10 Ortho-Mcneil Pharmaceutical, Inc. Aroyl aminoacyl pyrrole compounds and their pharmaceutical use

Also Published As

Publication number Publication date
US20020128286A1 (en) 2002-09-12
DE60129846T2 (de) 2008-05-08
JP2004517893A (ja) 2004-06-17
ES2291373T3 (es) 2008-03-01
EP1351950B1 (de) 2007-08-08
DK1351950T3 (da) 2007-12-03
PT1351950E (pt) 2007-10-02
CA2432776A1 (en) 2002-07-25
EP1351950A2 (de) 2003-10-15
CY1106922T1 (el) 2012-09-26
WO2002057253A2 (en) 2002-07-25
DE60129846D1 (de) 2007-09-20
WO2002057253A3 (en) 2002-10-24
US6492387B2 (en) 2002-12-10
AU2002243310A1 (en) 2002-07-30

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