ATE370127T1 - Pyrimidinische azyklonukleoside, verfahren zur ihrer herstellung und ihre verwendung - Google Patents

Pyrimidinische azyklonukleoside, verfahren zur ihrer herstellung und ihre verwendung

Info

Publication number
ATE370127T1
ATE370127T1 AT02703583T AT02703583T ATE370127T1 AT E370127 T1 ATE370127 T1 AT E370127T1 AT 02703583 T AT02703583 T AT 02703583T AT 02703583 T AT02703583 T AT 02703583T AT E370127 T1 ATE370127 T1 AT E370127T1
Authority
AT
Austria
Prior art keywords
sup
sub
group
azycloneucleosides
pyrimidinic
Prior art date
Application number
AT02703583T
Other languages
English (en)
Inventor
Jean Tronchet
Original Assignee
Univ Geneve
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0101165A external-priority patent/FR2820135B1/fr
Priority claimed from FR0108052A external-priority patent/FR2826006A1/fr
Application filed by Univ Geneve filed Critical Univ Geneve
Application granted granted Critical
Publication of ATE370127T1 publication Critical patent/ATE370127T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT02703583T 2001-01-29 2002-01-25 Pyrimidinische azyklonukleoside, verfahren zur ihrer herstellung und ihre verwendung ATE370127T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0101165A FR2820135B1 (fr) 2001-01-29 2001-01-29 Derives d'acyclonucleosides pyrimidiniques, leur procede de preparation et leur utilisation
FR0108052A FR2826006A1 (fr) 2001-06-19 2001-06-19 Derive d'acyclonucleoside pyrimidinique, son procede de preparation et son utilisation

Publications (1)

Publication Number Publication Date
ATE370127T1 true ATE370127T1 (de) 2007-09-15

Family

ID=26212851

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02703583T ATE370127T1 (de) 2001-01-29 2002-01-25 Pyrimidinische azyklonukleoside, verfahren zur ihrer herstellung und ihre verwendung

Country Status (7)

Country Link
US (1) US6911450B1 (de)
EP (1) EP1355887B1 (de)
CN (1) CN1231472C (de)
AT (1) ATE370127T1 (de)
CA (1) CA2436958A1 (de)
DE (1) DE60221794D1 (de)
WO (1) WO2002060880A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4323571B2 (ja) 1997-01-31 2009-09-02 エックスワイ， インコーポレイテッド 光学装置
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
CA2822983C (en) 2000-11-29 2017-05-09 Xy, Llc System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
US8211629B2 (en) 2002-08-01 2012-07-03 Xy, Llc Low pressure sperm cell separation system
CA2534394C (en) 2002-08-15 2013-01-08 Xy, Inc. High resolution flow cytometer
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
DK2959774T3 (da) 2003-03-28 2019-05-13 Inguran Llc Fremgangsmåde til kryokonservering af sædceller
WO2004104178A2 (en) 2003-05-15 2004-12-02 Xy, Inc. Efficient haploid cell sorting for flow cytometer systems
EP2260854A1 (de) 2004-03-29 2010-12-15 Inguran, LLC Spermasuspensionen zur Sortierung in X- oder Y-Chromosomen-tragende angereicherte Populationen
AU2005266930B2 (en) 2004-07-22 2010-09-16 Inguran, Llc Process for enriching a population of sperm cells
CN101784532B (zh) * 2007-06-29 2014-10-22 韩国化学研究院 Hiv逆转录酶抑制剂
KR20100041798A (ko) * 2007-06-29 2010-04-22 한국화학연구원 신규 ｈｉｖ 역전사효소 억제제
KR20100092960A (ko) * 2007-12-21 2010-08-23 한국화학연구원 Ｈｉｖ 역전사 효소 억제제의 제조 방법
RU2412154C1 (ru) * 2009-10-21 2011-02-20 Государственное образовательное учреждение высшего профессионального образования Волгоградский государственный технический университет (ВолгГТУ) Способ получения этиловых эфиров 2-алкил-4-арил-3-оксобутановых кислот
EP2725029A1 (de) 2012-10-29 2014-04-30 Laboratoire Biodim Neue antibakterielle Verbindungen und biologische Anwendungen dafür

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU205917B (en) 1989-09-29 1992-07-28 Mitsubishi Chem Ind Process for producing 6-substituted pyrimidine derivatives and antiviral pharmaceutical compositions containing them as active components
EP0631783A1 (de) * 1993-06-03 1995-01-04 Mitsubishi Chemical Corporation Antivirale Kombinationen von 2',3-Di-deoxyribonukleosiden mit 6-benzyl-1-ethoxy-methyl-5-substituierten Uracil-Derivaten

Also Published As

Publication number Publication date
CA2436958A1 (fr) 2002-08-08
US6911450B1 (en) 2005-06-28
EP1355887B1 (de) 2007-08-15
CN1231472C (zh) 2005-12-14
WO2002060880A1 (fr) 2002-08-08
DE60221794D1 (de) 2007-09-27
CN1492859A (zh) 2004-04-28
EP1355887A1 (de) 2003-10-29

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