ATE370127T1 - Pyrimidinische azyklonukleoside, verfahren zur ihrer herstellung und ihre verwendung - Google Patents
Pyrimidinische azyklonukleoside, verfahren zur ihrer herstellung und ihre verwendungInfo
- Publication number
- ATE370127T1 ATE370127T1 AT02703583T AT02703583T ATE370127T1 AT E370127 T1 ATE370127 T1 AT E370127T1 AT 02703583 T AT02703583 T AT 02703583T AT 02703583 T AT02703583 T AT 02703583T AT E370127 T1 ATE370127 T1 AT E370127T1
- Authority
- AT
- Austria
- Prior art keywords
- sup
- sub
- group
- azycloneucleosides
- pyrimidinic
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000005129 aryl carbonyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000005222 heteroarylaminocarbonyl group Chemical group 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0101165A FR2820135B1 (fr) | 2001-01-29 | 2001-01-29 | Derives d'acyclonucleosides pyrimidiniques, leur procede de preparation et leur utilisation |
| FR0108052A FR2826006A1 (fr) | 2001-06-19 | 2001-06-19 | Derive d'acyclonucleoside pyrimidinique, son procede de preparation et son utilisation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE370127T1 true ATE370127T1 (de) | 2007-09-15 |
Family
ID=26212851
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02703583T ATE370127T1 (de) | 2001-01-29 | 2002-01-25 | Pyrimidinische azyklonukleoside, verfahren zur ihrer herstellung und ihre verwendung |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6911450B1 (de) |
| EP (1) | EP1355887B1 (de) |
| CN (1) | CN1231472C (de) |
| AT (1) | ATE370127T1 (de) |
| CA (1) | CA2436958A1 (de) |
| DE (1) | DE60221794D1 (de) |
| WO (1) | WO2002060880A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2264427B1 (de) | 1997-01-31 | 2017-05-03 | Xy, Llc | Optisches Gerät mit fokussierendem Reflektor zur Konvergenz der Strahlung auf einen Partikelfluss, und zugehöriges Analyseverfahren |
| US6149867A (en) | 1997-12-31 | 2000-11-21 | Xy, Inc. | Sheath fluids and collection systems for sex-specific cytometer sorting of sperm |
| US7208265B1 (en) | 1999-11-24 | 2007-04-24 | Xy, Inc. | Method of cryopreserving selected sperm cells |
| US7713687B2 (en) | 2000-11-29 | 2010-05-11 | Xy, Inc. | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
| WO2002043486A1 (en) | 2000-11-29 | 2002-06-06 | Xy, Inc. | System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations |
| US8486618B2 (en) | 2002-08-01 | 2013-07-16 | Xy, Llc | Heterogeneous inseminate system |
| JP4595067B2 (ja) | 2002-08-01 | 2010-12-08 | エックスワイ,エルエルシー | 低圧精子細胞分離システム |
| CA2534394C (en) | 2002-08-15 | 2013-01-08 | Xy, Inc. | High resolution flow cytometer |
| US7169548B2 (en) | 2002-09-13 | 2007-01-30 | Xy, Inc. | Sperm cell processing and preservation systems |
| BRPI0408857B1 (pt) | 2003-03-28 | 2018-09-11 | Inguran Llc | aparelho, métodos e processos para separar partículas e para prover esperma de animal separado por sexo |
| ES2541121T3 (es) | 2003-05-15 | 2015-07-16 | Xy, Llc | Clasificación eficiente de células haploides por sistemas de citometría de flujo |
| DK2801363T3 (en) | 2004-03-29 | 2018-05-28 | Inguran Llc | PROCEDURE FOR STORING SORTED SPERMATOZOES |
| CA2574499C (en) | 2004-07-22 | 2016-11-29 | Monsanto Technology Llc | Process for enriching a population of sperm cells |
| ES2533863T3 (es) * | 2007-06-29 | 2015-04-15 | Korea Research Institute Of Chemical Technology | Inhibidores novedosos de la transcriptasa inversa de VIH |
| WO2009005693A1 (en) * | 2007-06-29 | 2009-01-08 | Gilead Sciences, Inc. | Novel hiv reverse transcriptase inhibitors |
| US8119800B2 (en) * | 2007-12-21 | 2012-02-21 | Korea Research Institute Of Chemical Technology | Processes for preparing HIV reverse transcriptase inhibitors |
| RU2412154C1 (ru) * | 2009-10-21 | 2011-02-20 | Государственное образовательное учреждение высшего профессионального образования Волгоградский государственный технический университет (ВолгГТУ) | Способ получения этиловых эфиров 2-алкил-4-арил-3-оксобутановых кислот |
| EP2725029A1 (de) | 2012-10-29 | 2014-04-30 | Laboratoire Biodim | Neue antibakterielle Verbindungen und biologische Anwendungen dafür |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU205917B (en) * | 1989-09-29 | 1992-07-28 | Mitsubishi Chem Ind | Process for producing 6-substituted pyrimidine derivatives and antiviral pharmaceutical compositions containing them as active components |
| EP0631783A1 (de) * | 1993-06-03 | 1995-01-04 | Mitsubishi Chemical Corporation | Antivirale Kombinationen von 2',3-Di-deoxyribonukleosiden mit 6-benzyl-1-ethoxy-methyl-5-substituierten Uracil-Derivaten |
-
2002
- 2002-01-25 US US10/470,564 patent/US6911450B1/en not_active Expired - Fee Related
- 2002-01-25 EP EP02703583A patent/EP1355887B1/de not_active Expired - Lifetime
- 2002-01-25 CA CA002436958A patent/CA2436958A1/fr not_active Abandoned
- 2002-01-25 CN CNB02805458XA patent/CN1231472C/zh not_active Expired - Fee Related
- 2002-01-25 DE DE60221794T patent/DE60221794D1/de not_active Expired - Lifetime
- 2002-01-25 AT AT02703583T patent/ATE370127T1/de not_active IP Right Cessation
- 2002-01-25 WO PCT/EP2002/000839 patent/WO2002060880A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US6911450B1 (en) | 2005-06-28 |
| CA2436958A1 (fr) | 2002-08-08 |
| EP1355887B1 (de) | 2007-08-15 |
| CN1231472C (zh) | 2005-12-14 |
| CN1492859A (zh) | 2004-04-28 |
| EP1355887A1 (de) | 2003-10-29 |
| WO2002060880A1 (fr) | 2002-08-08 |
| DE60221794D1 (de) | 2007-09-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |