ATE371655T1 - Farnesyl-protein-transferaseinhibitoren - Google Patents

Farnesyl-protein-transferaseinhibitoren

Info

Publication number: ATE371655T1
Authority: AT; Austria
Prior art keywords: transferas; inhibitors; farnesyl protein; farnesyl; protein
Prior art date: 2000-11-29

Application number

AT01985496T

Other languages

English (en)

Inventor

F Njoroge

Bancha Vibulbhan

Viyyoor Girijavallabhan

Xiongwei Shi

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-11-29

Filing date

2001-11-27

Publication date

2007-09-15

2001-11-27 Application filed by Schering Corp filed Critical Schering Corp

2007-09-15 Application granted granted Critical

2007-09-15 Publication of ATE371655T1 publication Critical patent/ATE371655T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines Containing Plant Substances (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT01985496T 2000-11-29 2001-11-27 Farnesyl-protein-transferaseinhibitoren ATE371655T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US25397100P	2000-11-29	2000-11-29

Publications (1)

Publication Number	Publication Date
ATE371655T1 true ATE371655T1 (de)	2007-09-15

Family

ID=22962414

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01985496T ATE371655T1 (de)	2000-11-29	2001-11-27	Farnesyl-protein-transferaseinhibitoren

Country Status (20)

Country	Link
US (1)	US6528523B2 (de)
EP (1)	EP1337522B1 (de)
JP (1)	JP2004514717A (de)
KR (1)	KR20030060939A (de)
CN (1)	CN1198816C (de)
AR (1)	AR035660A1 (de)
AT (1)	ATE371655T1 (de)
AU (2)	AU3514302A (de)
CA (1)	CA2429720C (de)
DE (1)	DE60130239T2 (de)
ES (1)	ES2291368T3 (de)
HK (1)	HK1054226A1 (de)
HU (1)	HUP0302104A2 (de)
IL (1)	IL155668A0 (de)
MX (1)	MXPA03004878A (de)
NZ (1)	NZ525572A (de)
PE (1)	PE20020635A1 (de)
TW (1)	TWI225058B (de)
WO (1)	WO2002044164A1 (de)
ZA (1)	ZA200303635B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7517890B2 (en)	2003-11-20	2009-04-14	Children's Hospital Medical Center	GTPase inhibitors and methods of use
AU2006275528B2 (en)	2005-07-29	2012-03-08	Children's Hospital Medical Center	GTPase inhibitors and methods of use and crystal structure of Rac-1 GTPase
WO2013166043A1 (en)	2012-05-02	2013-11-07	Children's Hospital Medical Center	Rejuvenation of precursor cells
US10028503B2 (en)	2014-06-18	2018-07-24	Children's Hospital Medical Center	Platelet storage methods and compositions for same
WO2021034616A1 (en)	2019-08-16	2021-02-25	Children' S Hospital Medical Center	Methods of treating a subject with a cdc42-specific inhibitor

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6365588B1 (en)	1993-10-15	2002-04-02	Schering Corporation	Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
US5661152A (en) *	1993-10-15	1997-08-26	Schering Corporation	Tricyclic sulfonamide compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
IL111235A (en) *	1993-10-15	2001-03-19	Schering Plough Corp	Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them
IL111257A0 (en) *	1993-10-15	1994-12-29	Schering Corp	Tricyclic sulfonamide compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
US5719148A (en)	1993-10-15	1998-02-17	Schering Corporation	Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
US5700806A (en)	1995-03-24	1997-12-23	Schering Corporation	Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
US5684013A (en)	1995-03-24	1997-11-04	Schering Corporation	Tricyclic compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
US5801175A (en)	1995-04-07	1998-09-01	Schering Corporation	Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
US5874442A (en)	1995-12-22	1999-02-23	Schering-Plough Corporation	Tricyclic amides useful for inhibition of G-protein function and for treatment of proliferative disease
MY119007A (en) *	1995-12-22	2005-03-31	Schering Corp	Tricyclic amides useful for inhibition of g-protein function and for treatment of proliferative diseases.
US5784442A (en)	1996-02-02	1998-07-21	Telefonaktiebologet Lm Ericsson (Publ)	System and method for real-time billing in a radio telecommunications network
US5925757A (en) *	1996-07-26	1999-07-20	Schering Corporation	Method for preparing carboxamides
US6071907A (en)	1996-09-13	2000-06-06	Schering Corporation	Tricyclic compounds useful as FPT inhibitors
US5985879A (en)	1996-09-13	1999-11-16	Schering Corporation	Compounds useful for inhibition of farnesyl protein transferase
US5945429A (en)	1996-09-13	1999-08-31	Schering Corporation	Compounds useful for inhibition of farnesyl protein transferase
US6040305A (en)	1996-09-13	2000-03-21	Schering Corporation	Compounds useful for inhibition of farnesyl protein transferase
US6030982A (en)	1996-09-13	2000-02-29	Schering Corporationm	Compounds useful for inhibition of farnesyl protein transferase
US5861395A (en)	1996-09-13	1999-01-19	Schering Corporation	Compounds useful for inhibition of farnesyl proteins transferase
US6358968B1 (en)	1997-06-17	2002-03-19	Schering Corporation	N-substituted urea inhibitors of farnesyl-protein transferase
US6211193B1 (en)	1997-06-17	2001-04-03	Schering Corporation	Compounds useful for inhibition of farnesyl protein transferase
US6159984A (en)	1997-06-17	2000-12-12	Schering Corporation	Farnesyl protein transferase inhibitors
IL133449A0 (en) *	1997-06-17	2001-04-30	Schering Corp	Benzo (5, 6) cyclohepta (1, 2-b) pyridine derivatives as farnesyl protein transferase inhibitors
US6228865B1 (en)	1997-06-17	2001-05-08	Schering Corporation	Compounds useful for inhibition of farnesyl protein transferase
US5925639A (en)	1997-06-17	1999-07-20	Schering Corporation	Keto amide derivatives useful as farnesyl protein transferase inhibitors
US5939416A (en)	1997-06-17	1999-08-17	Schering Corporation	Benzo (5,6) cycloheptapyridine compounds useful as farnesyl protein transferase inhibitors
US6051582A (en)	1997-06-17	2000-04-18	Schering Corporation	Compounds useful for inhibition of farnesyl protein transferase
US5852034A (en)	1997-06-17	1998-12-22	Schering Corporation	Benzo(5,6)cycloheptapyridine cyclic ureas and lactams useful as farnesyl protein transferase inhibitors
IL133393A0 (en) *	1997-06-17	2001-04-30	Schering Corp	Novel tricyclic sulfonamide inhibitors of farnesyl-protein transferase
US6239140B1 (en)	1997-06-17	2001-05-29	Schering Corporation	Compounds useful for inhibition of farnesyl protein transferase
US6221322B1 (en)	1997-11-27	2001-04-24	Dowa Mining Co., Ltd	Strontium nitrate and method for manufacturing same
US6096757A (en)	1998-12-21	2000-08-01	Schering Corporation	Method for treating proliferative diseases
US6362188B1 (en)	1998-12-18	2002-03-26	Schering Corporation	Farnesyl protein transferase inhibitors
US6372747B1 (en)	1998-12-18	2002-04-16	Schering Corporation	Farnesyl protein transferase inhibitors
US6432959B1 (en)	1998-12-23	2002-08-13	Schering Corporation	Inhibitors of farnesyl-protein transferase
US6410451B2 (en)	1999-09-27	2002-06-25	Lam Research Corporation	Techniques for improving etching in a plasma processing chamber

2001
- 2001-11-27 AR ARP010105505A patent/AR035660A1/es unknown
- 2001-11-27 CN CNB018194605A patent/CN1198816C/zh not_active Expired - Fee Related
- 2001-11-27 WO PCT/US2001/044333 patent/WO2002044164A1/en not_active Ceased
- 2001-11-27 AU AU3514302A patent/AU3514302A/xx active Pending
- 2001-11-27 EP EP01985496A patent/EP1337522B1/de not_active Expired - Lifetime
- 2001-11-27 AU AU2002235143A patent/AU2002235143B2/en not_active Ceased
- 2001-11-27 NZ NZ525572A patent/NZ525572A/en unknown
- 2001-11-27 ES ES01985496T patent/ES2291368T3/es not_active Expired - Lifetime
- 2001-11-27 JP JP2002546534A patent/JP2004514717A/ja active Pending
- 2001-11-27 CA CA002429720A patent/CA2429720C/en not_active Expired - Fee Related
- 2001-11-27 HU HU0302104A patent/HUP0302104A2/hu unknown
- 2001-11-27 KR KR10-2003-7006749A patent/KR20030060939A/ko not_active Ceased
- 2001-11-27 HK HK03106385.7A patent/HK1054226A1/zh unknown
- 2001-11-27 AT AT01985496T patent/ATE371655T1/de not_active IP Right Cessation
- 2001-11-27 DE DE60130239T patent/DE60130239T2/de not_active Expired - Lifetime
- 2001-11-27 IL IL15566801A patent/IL155668A0/xx unknown
- 2001-11-27 PE PE2001001188A patent/PE20020635A1/es not_active Application Discontinuation
- 2001-11-27 MX MXPA03004878A patent/MXPA03004878A/es active IP Right Grant
- 2001-11-27 US US09/995,156 patent/US6528523B2/en not_active Expired - Fee Related
- 2001-11-28 TW TW090129431A patent/TWI225058B/zh not_active IP Right Cessation
2003
- 2003-05-12 ZA ZA200303635A patent/ZA200303635B/en unknown

Also Published As

Publication number	Publication date
HUP0302104A2 (hu)	2003-09-29
ES2291368T3 (es)	2008-03-01
ZA200303635B (en)	2004-08-12
MXPA03004878A (es)	2003-08-19
AU2002235143B2 (en)	2006-03-02
CA2429720A1 (en)	2002-06-06
TWI225058B (en)	2004-12-11
WO2002044164A1 (en)	2002-06-06
JP2004514717A (ja)	2004-05-20
EP1337522A1 (de)	2003-08-27
KR20030060939A (ko)	2003-07-16
NZ525572A (en)	2004-11-26
US6528523B2 (en)	2003-03-04
CA2429720C (en)	2009-12-29
IL155668A0 (en)	2003-11-23
US20020115679A1 (en)	2002-08-22
AU3514302A (en)	2002-06-11
DE60130239D1 (en)	2007-10-11
CN1476444A (zh)	2004-02-18
CN1198816C (zh)	2005-04-27
DE60130239T2 (de)	2008-05-21
PE20020635A1 (es)	2002-07-11
HK1054226A1 (zh)	2003-11-21
EP1337522B1 (de)	2007-08-29
AR035660A1 (es)	2004-06-23

Legal Events

Date	Code	Title	Description
2008-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
CY2012007I2 (el)	2014-07-02	Πεπτιδομιμητικοι αναστολεις πρωτεασης
DE60234125D1 (de)	2009-12-03	E inhibitoren
DE60129794D1 (de)	2007-09-20	Pyrrol substituierte indolin-2-on protein kinase inhibitoren
PT1370553E (pt)	2006-09-29	Inibidores de rhoquinase
NO20034045D0 (no)	2003-09-12	Metallproteinase-inhibitorer
EP1324985A4 (de)	2004-10-06	Hemmstoffe der prenyl-protein transferase
EP1165084A4 (de)	2002-05-15	Inhibitoren der prenyl-proteintransferasen
EP1165082A4 (de)	2002-06-12	Inhibitoren der prenyl-protein-transferase
ATE293622T1 (de)	2005-05-15	Farnesyl protein transferase inhibitoren
NO20034032L (no)	2003-11-10	Metallproteinase-inhibitorer
DK1272488T3 (da)	2006-07-17	Tri-aryl-substitueret ethan-PDE4-inhibitorer
ATE255114T1 (de)	2003-12-15	Tricyclische proteinkinasehemmer
EP1158982A4 (de)	2002-06-12	Inhibitoren der Prenyl-Protein Transferase
NO20025786L (no)	2003-02-12	Protaseinhibitorer
DK1339695T3 (da)	2006-07-31	Farnesyltransferase-inhibitorer
NO20025005D0 (no)	2002-10-17	Proteaseinhibitorer
NO20025281D0 (no)	2002-11-04	Peptid-deformylase-inhibitorer
EE200200206A (et)	2003-04-15	Farnesüüli transferaasiinhibiitorid
ATE371655T1 (de)	2007-09-15	Farnesyl-protein-transferaseinhibitoren
AR028075A1 (es)	2003-04-23	Inhibidores de la peptido-desformilasa
DE60132468D1 (de)	2008-03-06	Alen-lanosterol zyklase inhibitoren
NO20032328D0 (no)	2003-05-22	Proteaseinhibitorer
EP1158983A4 (de)	2003-05-21	Inhibitoren der Prenyl-Protein Transferase
DK1296985T3 (da)	2005-10-03	Heteropolycykliske inhibitorer
SE0104413D0 (sv)	2001-12-21	New protein