DK1339695T3 - Farnesyltransferase-inhibitorer - Google Patents

Farnesyltransferase-inhibitorer

Info

Publication number
DK1339695T3
DK1339695T3 DK01273519T DK01273519T DK1339695T3 DK 1339695 T3 DK1339695 T3 DK 1339695T3 DK 01273519 T DK01273519 T DK 01273519T DK 01273519 T DK01273519 T DK 01273519T DK 1339695 T3 DK1339695 T3 DK 1339695T3
Authority
DK
Denmark
Prior art keywords
transferase inhibitors
farnesyl transferase
farnesyl
inhibitors
transferase
Prior art date
Application number
DK01273519T
Other languages
English (en)
Inventor
Akiyo K Claiborne
Stephen L Ii Gwaltney
Tomgmei Li
Robert A Mantei
Todd W Rockway
Yunsong Tong
Gary T Wang
Xilu Wang
Weibo Wang
Lisa A Hasvold
Qun Li
Nan-Horng Lin
Hing L Sham
Gerard M Sullivan
Le Wang
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of DK1339695T3 publication Critical patent/DK1339695T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DK01273519T 2000-11-30 2001-11-30 Farnesyltransferase-inhibitorer DK1339695T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72723000A 2000-11-30 2000-11-30
US09/912,677 US20020115640A1 (en) 2000-11-30 2001-07-25 Farnesyltransferase inhibitors

Publications (1)

Publication Number Publication Date
DK1339695T3 true DK1339695T3 (da) 2006-07-31

Family

ID=24921844

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01273519T DK1339695T3 (da) 2000-11-30 2001-11-30 Farnesyltransferase-inhibitorer

Country Status (30)

Country Link
US (1) US20020115640A1 (da)
EP (1) EP1339695B1 (da)
JP (1) JP2004519503A (da)
KR (1) KR20030060968A (da)
CN (1) CN1487924A (da)
AR (1) AR035375A1 (da)
AT (1) ATE323681T1 (da)
BG (1) BG107908A (da)
BR (1) BR0112028A (da)
CA (1) CA2430619A1 (da)
CY (1) CY1106104T1 (da)
CZ (1) CZ20031804A3 (da)
DE (1) DE60118955T2 (da)
DK (1) DK1339695T3 (da)
EC (1) ECSP034634A (da)
ES (1) ES2261340T3 (da)
HU (1) HUP0600331A2 (da)
IL (2) IL156212A0 (da)
MX (1) MXPA03004879A (da)
MY (1) MY136181A (da)
NO (1) NO20032471L (da)
NZ (1) NZ526313A (da)
PE (1) PE20020687A1 (da)
PL (1) PL363637A1 (da)
PT (1) PT1339695E (da)
SA (1) SA01220565B1 (da)
SI (1) SI1339695T1 (da)
SK (1) SK286686B6 (da)
UY (1) UY27046A1 (da)
WO (1) WO2002074747A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008539276A (ja) * 2005-04-27 2008-11-13 ユニバーシティ オブ フロリダ リサーチ ファウンデーション,インコーポレイティド ヒト疾患に関連する変異体タンパク質の分解能を改善するための材料及び方法
JP4592548B2 (ja) * 2005-08-24 2010-12-01 株式会社エヌ・ティ・ティ・ドコモ 送信電力制御方法及び移動通信システム
US7722316B2 (en) * 2005-09-13 2010-05-25 Rolls-Royce Power Engineering Plc Acoustic viscous damper for centrifugal gas compressor
US7790770B2 (en) 2005-11-23 2010-09-07 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
TW200806284A (en) * 2006-03-31 2008-02-01 Alcon Mfg Ltd Prenyltransferase inhibitors for ocular hypertension control and the treatment of glaucoma
US8084477B2 (en) * 2007-10-31 2011-12-27 Bristol-Myers Squibb Company Alpha-(N-sulfonamido)acetamide compound as an inhibitor of beta amyloid peptide production
US20110086834A1 (en) * 2008-06-26 2011-04-14 Amgen Inc. Alkynyl alcohols as kinase inhibitors
WO2012069193A1 (de) * 2010-11-26 2012-05-31 Reza Ghotbi Implant zur behandlung oder prävention eines aneurysmas
CN105693617B (zh) * 2014-11-24 2018-06-08 中国科学院大连化学物理研究所 一种tmsn3参与的还原环化反应制备4-咪唑甲醛衍生物的方法
EP3902100A1 (en) 2015-10-07 2021-10-27 Tc1 Llc Resonant power transfer systems having efficiency optimization based on receiver impedance
WO2018132791A1 (en) 2017-01-16 2018-07-19 The Regents Of The University Of California Treatment of neurodegenerative conditions by disruption of rhes
CN112851508B (zh) * 2019-11-27 2025-02-25 广东东阳光药业股份有限公司 一种巴洛沙韦中间体的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0891361A1 (en) * 1996-04-03 1999-01-20 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US6297239B1 (en) * 1997-10-08 2001-10-02 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
ATE289602T1 (de) * 1998-08-27 2005-03-15 Pfizer Prod Inc Quinolin-2-on-derivate verwendbar als antikrebsmittel

Also Published As

Publication number Publication date
AR035375A1 (es) 2004-05-12
CA2430619A1 (en) 2002-09-26
NO20032471L (no) 2003-07-25
SI1339695T1 (sl) 2006-10-31
NZ526313A (en) 2004-11-26
SK8232003A3 (en) 2004-01-08
EP1339695A1 (en) 2003-09-03
ES2261340T3 (es) 2006-11-16
ECSP034634A (es) 2003-07-25
IL156212A (en) 2008-11-26
SA01220565B1 (ar) 2007-01-27
UY27046A1 (es) 2002-07-31
MY136181A (en) 2008-08-29
BR0112028A (pt) 2004-02-17
DE60118955T2 (de) 2007-01-04
CY1106104T1 (el) 2011-06-08
KR20030060968A (ko) 2003-07-16
BG107908A (bg) 2004-01-30
HK1059260A1 (en) 2004-06-25
NO20032471D0 (no) 2003-05-30
CN1487924A (zh) 2004-04-07
PE20020687A1 (es) 2002-08-03
WO2002074747A1 (en) 2002-09-26
ATE323681T1 (de) 2006-05-15
EP1339695B1 (en) 2006-04-19
PL363637A1 (en) 2004-11-29
IL156212A0 (en) 2003-12-23
MXPA03004879A (es) 2004-05-04
CZ20031804A3 (cs) 2003-11-12
SK286686B6 (sk) 2009-03-05
PT1339695E (pt) 2006-08-31
DE60118955D1 (de) 2006-05-24
HUP0600331A2 (en) 2006-10-28
JP2004519503A (ja) 2004-07-02
US20020115640A1 (en) 2002-08-22

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