ATE371725T1 - Alkohol-dehydrogenase mit hoher stabilität gegenüber lösungsmittel und temperatur - Google Patents

Alkohol-dehydrogenase mit hoher stabilität gegenüber lösungsmittel und temperatur

Info

Publication number
ATE371725T1
ATE371725T1 AT03709768T AT03709768T ATE371725T1 AT E371725 T1 ATE371725 T1 AT E371725T1 AT 03709768 T AT03709768 T AT 03709768T AT 03709768 T AT03709768 T AT 03709768T AT E371725 T1 ATE371725 T1 AT E371725T1
Authority
AT
Austria
Prior art keywords
alcohol dehydrogenase
solvents
temperature
high stability
biocatalysts
Prior art date
Application number
AT03709768T
Other languages
English (en)
Inventor
Wolfgang Stampfer
Birgit Kosjek
Wolfgang Kroutil
Kurt Faber
Original Assignee
Biocatalytics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocatalytics Inc filed Critical Biocatalytics Inc
Application granted granted Critical
Publication of ATE371725T1 publication Critical patent/ATE371725T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
AT03709768T 2002-03-18 2003-03-10 Alkohol-dehydrogenase mit hoher stabilität gegenüber lösungsmittel und temperatur ATE371725T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02405204 2002-03-18

Publications (1)

Publication Number Publication Date
ATE371725T1 true ATE371725T1 (de) 2007-09-15

Family

ID=27838196

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03709768T ATE371725T1 (de) 2002-03-18 2003-03-10 Alkohol-dehydrogenase mit hoher stabilität gegenüber lösungsmittel und temperatur

Country Status (8)

Country Link
US (1) US7569375B2 (de)
EP (1) EP1485471B1 (de)
JP (1) JP2005520517A (de)
AT (1) ATE371725T1 (de)
AU (1) AU2003214111A1 (de)
CA (1) CA2474905A1 (de)
DE (1) DE60315958D1 (de)
WO (1) WO2003078615A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005520517A (ja) 2002-03-18 2005-07-14 チバ スペシャルティ ケミカルズ ホールディング インコーポレーテッド 高い溶媒および温度安定性を有するアルコールデヒドロゲナーゼ
JP2007502124A (ja) 2003-08-11 2007-02-08 コデクシス, インコーポレイテッド 改良ケトレダクターゼポリペプチドおよび関連ポリヌクレオチド
EP1664286A1 (de) * 2003-09-18 2006-06-07 Ciba SC Holding AG Alkoholdehydrogenasen mit erhöhter lösungsmittel- und temperaturstabiltät
AT501496B1 (de) * 2005-02-21 2007-03-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen
DE102005010804A1 (de) * 2005-03-07 2006-09-14 Basf Ag Verfahren zur Herstellung optisch aktiver Alkohole
AT502395B1 (de) * 2005-07-27 2007-03-15 Iep Gmbh Oxidoreduktasen zur stereoselektiven reduktion von ketoverbindungen
AT502185B1 (de) * 2005-09-23 2007-02-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen
US8956850B2 (en) 2008-06-05 2015-02-17 Butamax Advanced Biofuels Llc Enhanced pyruvate to acetolactate conversion in yeast
AT503017B1 (de) * 2005-12-19 2007-07-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von hydroxyketoverbindungen
DE102006009744A1 (de) * 2006-03-02 2007-09-06 Wacker Chemie Ag Herstellung von (S)-2-Butanol durch oxidative Racematspaltung
US8828704B2 (en) 2006-05-02 2014-09-09 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
US8962298B2 (en) 2006-05-02 2015-02-24 Butamax Advanced Biofuels Llc Recombinant host cell comprising a diol dehydratase
US7659104B2 (en) 2006-05-05 2010-02-09 E.I. Du Pont De Nemours And Company Solvent tolerant microorganisms and methods of isolation
US8426174B2 (en) 2007-05-02 2013-04-23 Butamax(Tm) Advanced Biofuels Llc Method for the production of 2-butanol
EP3450550A1 (de) 2008-03-05 2019-03-06 Genomatica, Inc. Primäre, alkohole produzierende organismen
US8188250B2 (en) 2008-04-28 2012-05-29 Butamax(Tm) Advanced Biofuels Llc Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans
AU2009296227A1 (en) * 2008-09-29 2010-04-01 Butamax(Tm) Advanced Biofuels Llc Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria
DE102008064575B4 (de) * 2008-12-31 2011-06-01 Barakat, Adil Verfahren zur Herstellung von 1-Hydroxyketon-Verbindungen
US8178329B2 (en) 2009-04-01 2012-05-15 Richard Allen Kohn Process to produce organic compounds from synthesis gases
EP2519628A2 (de) 2009-12-29 2012-11-07 Butamax (TM) Advanced Biofuels LLC Alkoholdehydrogenasen (adh) zur fermentativen herstellung von niederen alkylalkoholen
EP2963121A1 (de) 2014-07-03 2016-01-06 Basf Se Autarke biokatalytische Redoxaminierung von Alkoholen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3574682B2 (ja) * 1993-09-24 2004-10-06 ダイセル化学工業株式会社 新規な酵素、該酵素を製造する方法、該酵素をコードするdna、該dnaを含む形質転換体、該酵素による光学活性アルコール等の製造方法
JP2005520517A (ja) 2002-03-18 2005-07-14 チバ スペシャルティ ケミカルズ ホールディング インコーポレーテッド 高い溶媒および温度安定性を有するアルコールデヒドロゲナーゼ

Also Published As

Publication number Publication date
DE60315958D1 (de) 2007-10-11
CA2474905A1 (en) 2003-09-25
US20040157305A1 (en) 2004-08-12
WO2003078615A1 (en) 2003-09-25
US7569375B2 (en) 2009-08-04
EP1485471B1 (de) 2007-08-29
JP2005520517A (ja) 2005-07-14
EP1485471A1 (de) 2004-12-15
AU2003214111A1 (en) 2003-09-29

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