ATE371733T1 - Verfahren zur kontrollierten induktion somatischer mutationen und verwendung davon in proteomik - Google Patents

Verfahren zur kontrollierten induktion somatischer mutationen und verwendung davon in proteomik

Info

Publication number
ATE371733T1
ATE371733T1 AT02804929T AT02804929T ATE371733T1 AT E371733 T1 ATE371733 T1 AT E371733T1 AT 02804929 T AT02804929 T AT 02804929T AT 02804929 T AT02804929 T AT 02804929T AT E371733 T1 ATE371733 T1 AT E371733T1
Authority
AT
Austria
Prior art keywords
somatic mutations
proteomics
antibodies
controlled induction
induction
Prior art date
Application number
AT02804929T
Other languages
English (en)
Inventor
Claude-Agnes Reynaud
Jean-Claude Weill
Original Assignee
Mixis France Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0116352A external-priority patent/FR2833611B1/fr
Application filed by Mixis France Sa filed Critical Mixis France Sa
Application granted granted Critical
Publication of ATE371733T1 publication Critical patent/ATE371733T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
AT02804929T 2001-12-18 2002-12-17 Verfahren zur kontrollierten induktion somatischer mutationen und verwendung davon in proteomik ATE371733T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0116352A FR2833611B1 (fr) 2001-12-18 2001-12-18 Procede pour l'induction de mutations somatiques et son application en proteomique
FR0210078A FR2833612B1 (fr) 2001-12-18 2002-08-08 Procede pour l'induction maitrisee de mutations somatiques et son application en proteomique

Publications (1)

Publication Number Publication Date
ATE371733T1 true ATE371733T1 (de) 2007-09-15

Family

ID=26213302

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02804929T ATE371733T1 (de) 2001-12-18 2002-12-17 Verfahren zur kontrollierten induktion somatischer mutationen und verwendung davon in proteomik

Country Status (12)

Country Link
US (1) US20070196368A2 (de)
EP (1) EP1463816B1 (de)
JP (1) JP4354276B2 (de)
KR (3) KR101046532B1 (de)
AT (1) ATE371733T1 (de)
AU (1) AU2002364656B2 (de)
CA (1) CA2473085A1 (de)
DE (1) DE60222177T2 (de)
DK (1) DK1463816T3 (de)
ES (1) ES2292853T3 (de)
FR (1) FR2833612B1 (de)
WO (1) WO2003052098A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005003771A1 (en) * 2003-07-02 2005-01-13 Science & Technology Corporation @ Unm Two-layer antibody capture system
FR2875239B1 (fr) * 2004-09-10 2007-07-20 Inst Necker Ass Loi De 1901 Procede pour l'acceleration des mutations somatiques et son application en proteomique
FR2890660B1 (fr) * 2005-09-12 2007-11-30 Inst Necker Ass Loi De 1901 Procede pour l'acceleration des mutations somatiques et son application en proteomique
US20090075378A1 (en) * 2007-02-20 2009-03-19 Anaptysbio, Inc. Somatic hypermutation systems

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6352694B1 (en) * 1994-06-03 2002-03-05 Genetics Institute, Inc. Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells
US5885827A (en) * 1996-01-23 1999-03-23 The Regents Of The Universtiy Of California Eukaryotic high rate mutagenesis system
JP4302894B2 (ja) * 1998-10-09 2009-07-29 メディカル リサーチ カウンシル 多様性を生み出す方法

Also Published As

Publication number Publication date
US20050048051A1 (en) 2005-03-03
JP2005527192A (ja) 2005-09-15
JP4354276B2 (ja) 2009-10-28
ES2292853T3 (es) 2008-03-16
DK1463816T3 (da) 2008-01-02
FR2833612A1 (fr) 2003-06-20
FR2833612B1 (fr) 2006-01-27
EP1463816B1 (de) 2007-08-29
WO2003052098A3 (fr) 2004-01-22
AU2002364656B2 (en) 2008-05-08
DE60222177T2 (de) 2008-06-05
KR101046532B1 (ko) 2011-07-04
KR100998732B1 (ko) 2010-12-07
AU2002364656A1 (en) 2003-06-30
KR20110040960A (ko) 2011-04-20
DE60222177D1 (de) 2007-10-11
KR20100055544A (ko) 2010-05-26
CA2473085A1 (fr) 2003-06-26
US20070196368A2 (en) 2007-08-23
WO2003052098A2 (fr) 2003-06-26
EP1463816A2 (de) 2004-10-06
KR20040076870A (ko) 2004-09-03

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