DK1463816T3 - Fremgangsmåde til kontrolleret induktion af somatiske mutationer og anvendelse heraf inden for proteomik - Google Patents

Fremgangsmåde til kontrolleret induktion af somatiske mutationer og anvendelse heraf inden for proteomik

Info

Publication number
DK1463816T3
DK1463816T3 DK02804929T DK02804929T DK1463816T3 DK 1463816 T3 DK1463816 T3 DK 1463816T3 DK 02804929 T DK02804929 T DK 02804929T DK 02804929 T DK02804929 T DK 02804929T DK 1463816 T3 DK1463816 T3 DK 1463816T3
Authority
DK
Denmark
Prior art keywords
somatic mutations
proteomics
antibodies
controlled induction
induction
Prior art date
Application number
DK02804929T
Other languages
English (en)
Inventor
Claude-Agnes Reynaud
Jean-Claude Weill
Original Assignee
Mixis France Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0116352A external-priority patent/FR2833611B1/fr
Application filed by Mixis France Sa filed Critical Mixis France Sa
Application granted granted Critical
Publication of DK1463816T3 publication Critical patent/DK1463816T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102Mutagenizing nucleic acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
DK02804929T 2001-12-18 2002-12-17 Fremgangsmåde til kontrolleret induktion af somatiske mutationer og anvendelse heraf inden for proteomik DK1463816T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0116352A FR2833611B1 (fr) 2001-12-18 2001-12-18 Procede pour l'induction de mutations somatiques et son application en proteomique
FR0210078A FR2833612B1 (fr) 2001-12-18 2002-08-08 Procede pour l'induction maitrisee de mutations somatiques et son application en proteomique
PCT/FR2002/004375 WO2003052098A2 (fr) 2001-12-18 2002-12-17 Procede pour l'induction maitrisee de mutations somatiques et son apllication en proteomique

Publications (1)

Publication Number Publication Date
DK1463816T3 true DK1463816T3 (da) 2008-01-02

Family

ID=26213302

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02804929T DK1463816T3 (da) 2001-12-18 2002-12-17 Fremgangsmåde til kontrolleret induktion af somatiske mutationer og anvendelse heraf inden for proteomik

Country Status (12)

Country Link
US (1) US20070196368A2 (da)
EP (1) EP1463816B1 (da)
JP (1) JP4354276B2 (da)
KR (3) KR101046532B1 (da)
AT (1) ATE371733T1 (da)
AU (1) AU2002364656B2 (da)
CA (1) CA2473085A1 (da)
DE (1) DE60222177T2 (da)
DK (1) DK1463816T3 (da)
ES (1) ES2292853T3 (da)
FR (1) FR2833612B1 (da)
WO (1) WO2003052098A2 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050118728A1 (en) * 2003-07-02 2005-06-02 Caldwell Kevin K. Two-layer antibody capture system
FR2875239B1 (fr) * 2004-09-10 2007-07-20 Inst Necker Ass Loi De 1901 Procede pour l'acceleration des mutations somatiques et son application en proteomique
FR2890660B1 (fr) * 2005-09-12 2007-11-30 Inst Necker Ass Loi De 1901 Procede pour l'acceleration des mutations somatiques et son application en proteomique
NZ579010A (en) * 2007-02-20 2012-03-30 Anaptysbio Inc Somatic hypermutation systems

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6352694B1 (en) * 1994-06-03 2002-03-05 Genetics Institute, Inc. Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells
US5885827A (en) * 1996-01-23 1999-03-23 The Regents Of The Universtiy Of California Eukaryotic high rate mutagenesis system
JP4302894B2 (ja) * 1998-10-09 2009-07-29 メディカル リサーチ カウンシル 多様性を生み出す方法

Also Published As

Publication number Publication date
ES2292853T3 (es) 2008-03-16
AU2002364656B2 (en) 2008-05-08
DE60222177D1 (de) 2007-10-11
FR2833612B1 (fr) 2006-01-27
JP2005527192A (ja) 2005-09-15
KR101046532B1 (ko) 2011-07-04
US20050048051A1 (en) 2005-03-03
DE60222177T2 (de) 2008-06-05
US20070196368A2 (en) 2007-08-23
EP1463816A2 (fr) 2004-10-06
KR20040076870A (ko) 2004-09-03
KR20110040960A (ko) 2011-04-20
ATE371733T1 (de) 2007-09-15
CA2473085A1 (fr) 2003-06-26
FR2833612A1 (fr) 2003-06-20
WO2003052098A3 (fr) 2004-01-22
WO2003052098A2 (fr) 2003-06-26
KR20100055544A (ko) 2010-05-26
KR100998732B1 (ko) 2010-12-07
AU2002364656A1 (en) 2003-06-30
EP1463816B1 (fr) 2007-08-29
JP4354276B2 (ja) 2009-10-28

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