ATE372166T1 - Testgerät zur durchführung von nukleinsäure- amplifikationsreaktionen - Google Patents

Testgerät zur durchführung von nukleinsäure- amplifikationsreaktionen

Info

Publication number
ATE372166T1
ATE372166T1 AT00967055T AT00967055T ATE372166T1 AT E372166 T1 ATE372166 T1 AT E372166T1 AT 00967055 T AT00967055 T AT 00967055T AT 00967055 T AT00967055 T AT 00967055T AT E372166 T1 ATE372166 T1 AT E372166T1
Authority
AT
Austria
Prior art keywords
nucleic acid
acid amplification
test device
amplification reactions
performing nucleic
Prior art date
Application number
AT00967055T
Other languages
English (en)
Inventor
Brian Kluttz
Lawrence Burg
Garry Tegeler
Louis Graziano
Christopher Cotter
Michel Guy
James Greer
Geoff Mckinley
Luigi Catanzariti
Robert Glassford
James Bishop
Bruno Colin
Cecile Paris
Thomas Wang
Michael Morin
Original Assignee
Bio Merieux Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Merieux Inc filed Critical Bio Merieux Inc
Application granted granted Critical
Publication of ATE372166T1 publication Critical patent/ATE372166T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/026Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0825Test strips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B01L2400/049Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0633Valves, specific forms thereof with moving parts
    • B01L2400/0644Valves, specific forms thereof with moving parts rotary valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0633Valves, specific forms thereof with moving parts
    • B01L2400/0655Valves, specific forms thereof with moving parts pinch valves
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346Heating or cooling arrangements
    • G01N2035/00356Holding samples at elevated temperature (incubation)
    • G01N2035/00366Several different temperatures used

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
AT00967055T 1999-10-18 2000-09-29 Testgerät zur durchführung von nukleinsäure- amplifikationsreaktionen ATE372166T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/420,139 US6410275B1 (en) 1997-05-02 1999-10-18 Disposable test devices for performing nucleic acid amplification reactions

Publications (1)

Publication Number Publication Date
ATE372166T1 true ATE372166T1 (de) 2007-09-15

Family

ID=23665241

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00967055T ATE372166T1 (de) 1999-10-18 2000-09-29 Testgerät zur durchführung von nukleinsäure- amplifikationsreaktionen

Country Status (13)

Country Link
US (1) US6410275B1 (de)
EP (1) EP1146961B1 (de)
JP (1) JP2003512032A (de)
KR (1) KR20010093850A (de)
AT (1) ATE372166T1 (de)
AU (1) AU753903B2 (de)
BR (1) BR0007223A (de)
CA (1) CA2348691A1 (de)
DE (1) DE60036277T2 (de)
ES (1) ES2292473T3 (de)
IL (1) IL141985A0 (de)
MX (1) MXPA01003181A (de)
WO (1) WO2001028683A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6429007B1 (en) * 1997-05-02 2002-08-06 BIOMéRIEUX, INC. Nucleic acid amplification reaction station for disposable test devices
DE10306018A1 (de) * 2003-02-13 2004-09-09 Siemens Ag Analyse- und Diagnostikinstrument
US7090803B1 (en) * 2003-10-28 2006-08-15 American Bio Medica Corporation Lateral flow immunoassay device
US7939030B2 (en) 2003-10-29 2011-05-10 Mec Dynamics Corp. Micro mechanical methods and systems for performing assays
WO2006123660A1 (ja) * 2005-05-17 2006-11-23 Wako Pure Chemical Industries, Ltd. 連結試薬容器
CA3179247A1 (en) * 2005-12-21 2007-07-05 Meso Scale Technologies, Llc Assay modules having assay reagents and methods of making and using same
EP1963854B1 (de) 2005-12-21 2021-02-03 Meso Scale Technologies, LLC Assay-vorrichtungen, -verfahren und -reagenzien
CN101443441A (zh) * 2006-05-11 2009-05-27 株式会社岛津制作所 反应容器套件
ES2688281T3 (es) 2006-07-28 2018-10-31 Diagnostics For The Real World, Ltd Dispositivo, sistema y método para procesar una muestra
JP4933301B2 (ja) * 2007-02-22 2012-05-16 キヤノン株式会社 検体処理装置
CA2682761C (en) 2007-04-04 2015-10-13 Network Biosystems, Inc. Methods for rapid multiplexed amplification of target nucleic acids
US9458451B2 (en) 2007-06-21 2016-10-04 Gen-Probe Incorporated Multi-channel optical measurement instrument
GB2456079B (en) 2007-08-17 2010-07-14 Diagnostics For The Real World Device, system and method for processing a sample
DE102008007352B4 (de) 2008-01-28 2010-04-22 Prionics Ag Vorrichtung zur Gewinnung, Konservierung und Lagerung von Probenmaterial mit einem Probenbehälter
EP2443254A2 (de) 2009-06-15 2012-04-25 NetBio, Inc. Verbesserte verfahren für forensische dna-quantifizierung
WO2014087149A2 (en) * 2012-12-03 2014-06-12 The Secretary Of State For Environment, Food And Rural Affairs Device and apparatus
KR101955330B1 (ko) * 2012-12-21 2019-03-07 삼성전자주식회사 핵산 분석용 반응 시약 공급 장치
US9481903B2 (en) 2013-03-13 2016-11-01 Roche Molecular Systems, Inc. Systems and methods for detection of cells using engineered transduction particles
US10393738B2 (en) 2013-11-12 2019-08-27 Boditech Med Inc. Multi-well cuvette provided with integrated reaction and detection means
CN107148425B (zh) 2014-10-29 2021-08-03 拜斯科阿迪有限公司 对mt1-mmp特异性的双环肽配体
US10351893B2 (en) 2015-10-05 2019-07-16 GeneWeave Biosciences, Inc. Reagent cartridge for detection of cells
JP6858540B2 (ja) 2016-12-08 2021-04-14 株式会社ミズホメディー 核酸増幅反応用デバイス
US11077444B2 (en) * 2017-05-23 2021-08-03 Roche Molecular Systems, Inc. Packaging for a molecular diagnostic cartridge
EP3645549A1 (de) 2017-06-26 2020-05-06 BicycleRD Limited Bicyclische peptidliganden mit nachweisbaren anteilen und deren verwendung
JP7670481B2 (ja) 2017-08-04 2025-04-30 バイスクルテクス・リミテッド Cd137に対して特異的な二環式ペプチドリガンド
CN107523487B (zh) * 2017-09-18 2024-03-19 星源智(珠海)生物科技有限公司 一种集成化管状反应装置
CN111902429A (zh) 2018-02-23 2020-11-06 拜斯科技术开发有限公司 多聚体双环肽配体
US10935149B2 (en) 2018-03-15 2021-03-02 University Of Washington Temperature-actuated valve, fluidic device, and related methods of use
GB201820288D0 (en) 2018-12-13 2019-01-30 Bicycle Tx Ltd Bicycle peptide ligaands specific for MT1-MMP
GB201820325D0 (en) 2018-12-13 2019-01-30 Bicyclerd Ltd Bicyclic peptide ligands specific for psma
GB201820295D0 (en) 2018-12-13 2019-01-30 Bicyclerd Ltd Bicyclic peptide ligands specific for MT1-MMP
WO2020128527A1 (en) 2018-12-21 2020-06-25 Bicyclerd Limited Bicyclic peptide ligands specific for pd-l1
US12492224B2 (en) 2018-12-21 2025-12-09 Bicycletx Limited Bicyclic peptide ligands specific for PD-L1
TWI860386B (zh) 2019-07-30 2024-11-01 英商拜西可泰克斯有限公司 異質雙環肽複合物
JP2023531510A (ja) * 2020-06-24 2023-07-24 プレジデント アンド フェローズ オブ ハーバード カレッジ 自動マルチステップ反応デバイス
AU2021322934A1 (en) 2020-08-03 2023-03-30 Bicycletx Limited Peptide-based linkers

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3579303A (en) 1968-03-06 1971-05-18 Donald E Pickering System for handling specimens and other substances in medicine and physical sciences
US3833406A (en) 1972-08-07 1974-09-03 Owens Illinois Inc Closed container with desiccant coating on inside surface thereof
US3994594A (en) 1975-08-27 1976-11-30 Technicon Instruments Corporation Cuvette and method of use
US4207394A (en) 1976-01-28 1980-06-10 Mcdonnell Douglas Corporation Process and apparatus for analyzing specimens for the presence of microorganisms therein
US4043678A (en) 1976-03-01 1977-08-23 Technicon Instruments Corporation Cuvette
US4119407A (en) 1976-03-08 1978-10-10 Bio-Dynamics, Inc. Cuvette with reagent release means
US4116775A (en) 1976-05-03 1978-09-26 Mcdonnell Douglas Corporation Machine and process for reading cards containing medical specimens
US4038151A (en) 1976-07-29 1977-07-26 Mcdonnell Douglas Corporation Card for use in an automated microbial detection system
US4106675A (en) 1976-12-22 1978-08-15 The Kendall Company Liquid sampling device
US4195060A (en) 1978-02-08 1980-03-25 Abbott Laboratories Liquid reagent cartridge cuvette
US4330627A (en) 1979-02-09 1982-05-18 Ryder International Corporation Testing tray
US4267833A (en) 1979-04-24 1981-05-19 American Hospital Supply Corporation Method of flushing a medical fluid
US4332769A (en) 1980-09-10 1982-06-01 Chemetrics, Inc. Disposable titration device
US4605536A (en) 1984-05-29 1986-08-12 Veb Metaplast Quedlinburg Cuvette for projection display of chemical experiments
FR2612297B1 (fr) 1987-03-10 1990-10-05 Pasteur Diagnostics Dispositif de laboratoire pour analyse necessitant la mise en contact transitoire d'une phase solide et d'une phase liquide
US4956148A (en) 1987-04-22 1990-09-11 Abbott Laboratories Locking rack and disposable sample cartridge
US4943522A (en) 1987-06-01 1990-07-24 Quidel Lateral flow, non-bibulous membrane assay protocols
WO1989001050A1 (en) 1987-07-31 1989-02-09 The Board Of Trustees Of The Leland Stanford Junior University Selective amplification of target polynucleotide sequences
IL88073A0 (en) 1987-12-17 1989-06-30 Miles Inc Analytical reagent mixing apparatus and method for performing sequential analytical reactions
US5229297A (en) 1989-02-03 1993-07-20 Eastman Kodak Company Containment cuvette for PCR and method of use
DE4021628A1 (de) 1990-07-06 1992-01-16 Kiha Textilien Gmbh Faserstruktur und daraus erhaltenes formteil sowie verfahren zu dessen herstellung
US5270183A (en) 1991-02-08 1993-12-14 Beckman Research Institute Of The City Of Hope Device and method for the automated cycling of solutions between two or more temperatures
US5324481A (en) 1991-06-03 1994-06-28 Abbott Laboratories Carousel for assay specimen carrier
FR2679255B1 (fr) 1991-07-17 1993-10-22 Bio Merieux Procede d'immobilisation d'un fragment nucleique par fixation passive sur un support solide, support solide ainsi obtenu et son utilisation.
US5605665A (en) 1992-03-27 1997-02-25 Abbott Laboratories Reaction vessel
US5498392A (en) 1992-05-01 1996-03-12 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
US5587128A (en) 1992-05-01 1996-12-24 The Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification devices
KR100249110B1 (ko) 1992-05-06 2000-04-01 다니엘 엘. 캐시앙 핵산 서열 증폭 방법, 이에 이용되는 조성물 및 키트
US5364591A (en) 1992-06-01 1994-11-15 Eastman Kodak Company Device for moving a target-bearing solid through a liquid for detection while being contained
DE69429038T2 (de) 1993-07-28 2002-03-21 Pe Corporation (Ny), Norwalk Vorrichtung und Verfahren zur Nukleinsäurevervielfältigung
US5645801A (en) 1993-10-21 1997-07-08 Abbott Laboratories Device and method for amplifying and detecting target nucleic acids
CA2173861C (en) 1993-10-22 2003-12-23 Kathleen A. Hanley Reaction tube and method of use to minimize contamination
ATE193465T1 (de) 1994-01-06 2000-06-15 Johnson & Johnson Clin Diag Vorrichtung zum erwärmen einer flüssigkeitsführenden kammer von einer reaktionscuvette
US5725831A (en) 1994-03-14 1998-03-10 Becton Dickinson And Company Nucleic acid amplification apparatus
CA2143365A1 (en) 1994-03-14 1995-09-15 Hugh V. Cottingham Nucleic acid amplification method and apparatus
JPH10505224A (ja) 1994-06-10 1998-05-26 ジョージタウン、ユニバーシティー 組換えウイルスおよびその関連定量法
US5888826A (en) 1994-06-30 1999-03-30 Dade Behring Inc. Combination reagent holding and test device
US5602037A (en) 1994-06-30 1997-02-11 Dade International, Inc. Combination reagent holding and test device
US5639428A (en) * 1994-07-19 1997-06-17 Becton Dickinson And Company Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay
US5556771A (en) 1995-02-10 1996-09-17 Gen-Probe Incorporated Stabilized compositions of reverse transcriptase and RNA polymerase for nucleic acid amplification
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
WO1997003348A1 (en) 1995-07-13 1997-01-30 Immunological Associates Of Denver Self-contained device integrating nucleic acid extraction, amplification and detection
JPH09262084A (ja) 1996-03-27 1997-10-07 Technol Res Assoc Of Medical & Welfare Apparatus Dna増幅装置
US5989499A (en) 1997-05-02 1999-11-23 Biomerieux, Inc. Dual chamber disposable reaction vessel for amplification reactions
US5786182A (en) 1997-05-02 1998-07-28 Biomerieux Vitek, Inc. Dual chamber disposable reaction vessel for amplification reactions, reaction processing station therefor, and methods of use
CA2339163C (en) 1998-08-10 2010-01-12 Genomic Solutions, Inc. Thermal and fluidic cycling device for nucleic acid hybridization

Also Published As

Publication number Publication date
WO2001028683A8 (en) 2001-09-07
JP2003512032A (ja) 2003-04-02
IL141985A0 (en) 2002-03-10
DE60036277T2 (de) 2008-06-05
DE60036277D1 (de) 2007-10-18
US6410275B1 (en) 2002-06-25
WO2001028683A1 (en) 2001-04-26
CA2348691A1 (en) 2001-04-26
AU753903B2 (en) 2002-10-31
EP1146961B1 (de) 2007-09-05
BR0007223A (pt) 2001-12-04
ES2292473T3 (es) 2008-03-16
KR20010093850A (ko) 2001-10-29
AU7731200A (en) 2001-04-30
EP1146961A1 (de) 2001-10-24
MXPA01003181A (es) 2003-05-15

Similar Documents

Publication Publication Date Title
ATE372166T1 (de) Testgerät zur durchführung von nukleinsäure- amplifikationsreaktionen
DE60141044D1 (de) System zum erkennen von substanzen
DE68901632D1 (de) Reaktionsgefaess zur durchfuehrung von aufeinanderfolgenden analytischen testen.
DE69727932D1 (de) Vorrichtung und verfahren zur durchführung und überwachung von polymerase kettenreaktionen
FI883868A7 (fi) Anturi biologista, biokemiallista ja kemiallista koestusta varten
DE60136335D1 (de) Parallele genotypisierung mehrerer patientenproben
DE60031997D1 (de) Umkehrtransfektionsverfahren
EP2107482A3 (de) Verfahren und System zur Analyse von Reaktionen mittels eines Informationssystems
DE69033796D1 (de) Verfahren und gerät zum nachweis und zur quantifizierung von glukose in körperflüssigkeiten
ATE462492T1 (de) Vorrichtung zur detektion von targetmolekülen
DE60212614D1 (de) Vorrichtung zur dosierung von reagenzien
DK0970240T3 (da) Kunstig fejlparringshydridisering
DE602004020986D1 (de) Biologische vorrichtung
DE69716543D1 (de) Vorrichtung zum Entnehmen und Analysieren von flüssigen Proben, wie Blutproben
ATE76508T1 (de) Vorrichtung zur feststellung von okkultem blut.
DE60027045D1 (de) Oligonukleotide und diese enthaltende komplexe zur detektion der anwesenheit oder abwesenheit einer zielnukleinsäure in einer probe
DE69814848D1 (de) Untersuchung von nukleotiden in loesung mit hilfe von pna-sonden
DE59203610D1 (de) Reaktor zur Durchführung biologischer Reaktionen mittels Biokatalysatoren.
ES8801731A1 (es) Un aparato para realizar un analisis
ATE269161T1 (de) Kontaktierungsvorrichtung
NO870794L (no) FremgangsmŸte til kvantitativ bestemmelse av nukleinsyremolekyler og reagenspakke til bruk ved utfelse av fremgang smŸten.
IS7640A (is) Samsömun á fákirnum til hremmingar, greiningar ogmagngreiningar á lifrarbólgu A veirukjarnsýru
DE68909997D1 (de) Vorrichtung zur Kultur von tierischen Zellen, Kulturmethode und Mittel zum Nachweis der Kultur.
DE59906395D1 (de) Vorrichtung zur durchführung von chemischen reaktionen
DE69935588D1 (de) Modulation molekularer wechselwirkungspositionen in rns und anderen biomolekülen

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties