ATE373502T1 - Carbostyril-derivative zur beschleunigten speichelabsonderung - Google Patents

Carbostyril-derivative zur beschleunigten speichelabsonderung

Info

Publication number: ATE373502T1
Authority: AT; Austria
Prior art keywords: carbostyril; saliva; accelerated; xerostomia; prophylaxis
Prior art date: 2003-07-30

Application number

AT04747458T

Other languages

English (en)

Inventor

Hisashi Nagamoto

Masayuki Kohashi

Hiroshi Oka

Original Assignee

Otsuka Pharma Co Ltd

Univ School St Marianna

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-07-30

Filing date

2004-07-07

Publication date

2007-10-15

2004-07-07 Application filed by Otsuka Pharma Co Ltd, Univ School St Marianna filed Critical Otsuka Pharma Co Ltd

2007-10-15 Application granted granted Critical

2007-10-15 Publication of ATE373502T1 publication Critical patent/ATE373502T1/de

Links

LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical class C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 title abstract 4
210000003296 saliva Anatomy 0.000 title 1
208000005946 Xerostomia Diseases 0.000 abstract 3
206010039424 Salivary hypersecretion Diseases 0.000 abstract 2
206010013781 dry mouth Diseases 0.000 abstract 2
239000008194 pharmaceutical composition Substances 0.000 abstract 2
238000011321 prophylaxis Methods 0.000 abstract 2
208000026451 salivation Diseases 0.000 abstract 2
238000011282 treatment Methods 0.000 abstract 2
239000004480 active ingredient Substances 0.000 abstract 1
-1 carbostyril compound Chemical class 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
238000006467 substitution reaction Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Quinoline Compounds (AREA)
Enzymes And Modification Thereof (AREA)

AT04747458T 2003-07-30 2004-07-07 Carbostyril-derivative zur beschleunigten speichelabsonderung ATE373502T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2003282691		2003-07-30
JP2004021808		2004-01-29

Publications (1)

Publication Number	Publication Date
ATE373502T1 true ATE373502T1 (de)	2007-10-15

Family

ID=34117911

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04747458T ATE373502T1 (de)	2003-07-30	2004-07-07	Carbostyril-derivative zur beschleunigten speichelabsonderung

Country Status (9)

Country	Link
US (1)	US7879877B2 (de)
EP (1)	EP1648563B1 (de)
JP (1)	JP4394686B2 (de)
KR (1)	KR100681360B1 (de)
CN (1)	CN1859948B (de)
AT (1)	ATE373502T1 (de)
DE (1)	DE602004009079T2 (de)
MY (1)	MY142739A (de)
WO (1)	WO2005011811A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2006112961A2 (en)	2005-03-03	2006-10-26	Takasago International Corp. (Usa)	Synergistic salivation components
CN101910116B (zh)	2008-01-18	2013-06-19	高砂香料工业株式会社	(2e，6z，8e)-n-异丁基-2，6，8-癸三烯酰胺(千日菊酰胺)的制备方法，以及包含该化合物的食品或饮料、香料或化妆品、或药物
WO2010047681A1 (en) *	2008-10-24	2010-04-29	Bridge Pharma, Inc.	Treating xerophthalmia with norketotifen
US9597278B2 (en)	2008-11-13	2017-03-21	David A. Hamlin	Compositions and methods for alleviating hyposalivation and for providing oral comfort
US9884082B2 (en)	2008-11-13	2018-02-06	David A. Hamlin	Compositions and methods for alleviating hyposalivation and for providing oral comfort
WO2010059894A1 (en) *	2008-11-21	2010-05-27	Bridge Pharma, Inc.	Ocular formulations of norketotifen
US9248196B2 (en)	2011-02-25	2016-02-02	Nuformix Limited	Rebamipide complexes and cocrystals
US20140010882A1 (en)	2011-03-24	2014-01-09	Takakuni Matsuda	Pharmaceutical composition for treating a disease in the oral cavity comprising rebamipide
JP6710040B2 (ja) *	2015-11-06	2020-06-17	江崎グリコ株式会社	唾液分泌促進剤及び口腔用組成物
KR102190019B1 (ko) *	2018-10-23	2020-12-15	삼진제약주식회사	쇼그렌 증후군 예방 또는 치료용 조성물
US12083209B2 (en)	2020-02-18	2024-09-10	Sunstar Americas, Inc.	Oral care composition
EP4001434B1 (de) *	2020-11-18	2025-07-02	Korea Institute of Science and Technology	Speichelbiomarker zur diagnose von xerostomie und seine verwendung

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4322425A (en) *	1980-03-14	1982-03-30	Otsuka Pharmaceutical Co., Ltd.	Compositions for treating glaucoma
US4578381A (en) *	1982-07-05	1986-03-25	Otsuka Pharmaceutical Co., Ltd.	Carbostyril derivatives
JP2812998B2 (ja)	1989-08-14	1998-10-22	大塚製薬株式会社	胃炎治療剤
DK0543018T3 (da) *	1991-06-07	1996-02-05	Otsuka Pharma Co Ltd	Antidiabetikum
TW227558B (de)	1992-05-14	1994-08-01	Otsuka Pharma Co Ltd
JP2872546B2 (ja) *	1992-11-26	1999-03-17	大塚製薬株式会社	腸粘膜障害保護剤
CN1105799A (zh)	1993-03-18	1995-07-26	大制药株式会社	作为基质金属蛋白酶抑制剂的喹诺酮衍生物
JP2839827B2 (ja)	1993-10-05	1998-12-16	大塚製薬株式会社	ウレアーゼ阻害剤
WO1995011026A1 (en) *	1993-10-21	1995-04-27	Otsuka Pharmaceutical Co., Ltd.	Carbostyril derivative for inhibiting production of interleukin-8
MX9701010A (es)	1994-08-10	1997-05-31	Otsuka Pharma Co Ltd	Un preventivo y un remedio para herida y/o inflamacion oftalmica.
JPH0971532A (ja)	1995-09-06	1997-03-18	Otsuka Pharmaceut Co Ltd	発癌抑制剤
AR004214A1 (es) *	1995-10-12	1998-11-04	Otsuka Pharma Co Ltd	Una preparación de gotas oftálmicas para la cura de enfermedades oftálmicas
AR010771A1 (es)	1996-12-16	2000-07-12	Otsuka Pharma Co Ltd	Inhibidor del complejo adp-ribosiltransferasa, agente para curar una enfermedad infecciosa y uso del mismo.
JPH11228413A (ja)	1998-02-20	1999-08-24	Otsuka Pharmaceut Co Ltd	Ｎａｄアーゼ阻害剤

2004
- 2004-07-07 CN CN2004800279758A patent/CN1859948B/zh not_active Expired - Fee Related
- 2004-07-07 EP EP04747458A patent/EP1648563B1/de not_active Expired - Lifetime
- 2004-07-07 KR KR1020067001933A patent/KR100681360B1/ko not_active Expired - Fee Related
- 2004-07-07 WO PCT/JP2004/009992 patent/WO2005011811A1/en not_active Ceased
- 2004-07-07 US US10/566,214 patent/US7879877B2/en not_active Expired - Fee Related
- 2004-07-07 JP JP2006521775A patent/JP4394686B2/ja not_active Expired - Fee Related
- 2004-07-07 AT AT04747458T patent/ATE373502T1/de not_active IP Right Cessation
- 2004-07-07 DE DE602004009079T patent/DE602004009079T2/de not_active Expired - Lifetime
- 2004-07-24 MY MYPI20042986A patent/MY142739A/en unknown

Also Published As

Publication number	Publication date
KR20060037408A (ko)	2006-05-03
US7879877B2 (en)	2011-02-01
JP4394686B2 (ja)	2010-01-06
HK1097474A1 (zh)	2007-06-29
JP2006528662A (ja)	2006-12-21
CN1859948A (zh)	2006-11-08
DE602004009079D1 (de)	2007-10-31
EP1648563B1 (de)	2007-09-19
EP1648563A1 (de)	2006-04-26
US20070112026A1 (en)	2007-05-17
MY142739A (en)	2010-12-31
KR100681360B1 (ko)	2007-02-12
DE602004009079T2 (de)	2008-06-19
CN1859948B (zh)	2010-05-26
WO2005011811A1 (en)	2005-02-10

Legal Events

Date	Code	Title	Description
2008-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

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NO20052739L (no)	2005-08-19	CCR5-antagonister som medikamenter
UA94901C2 (ru)	2011-06-25	Антибактериальные производные пиперидина
EE200300403A (et)	2003-12-15	N-asendatud mittearomaatne heterotsükliline ühend, seda sisaldav ravimkompositsioon ning ühendi kasutamine ravimina
CY1111693T1 (el)	2015-10-07	Αντιιικοι παραγοντες
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PL369108A1 (en)	2005-04-18	17beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
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BR0316771A (pt)	2005-10-25	Compostos para o tratamento ou a prevenção de infecções por flavivirus, uso de um composto e composição farmacêutica
BR0208741A (pt)	2004-06-22	Derivados de piperidina
ATE413388T1 (de)	2008-11-15	Muskarin antagonisten
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ATE373502T1 (de)	2007-10-15	Carbostyril-derivative zur beschleunigten speichelabsonderung
DE602004008959D1 (de)	2007-10-25	Benzoäbüä1,4üdioxepinderivate
ES2186550A1 (es)	2003-05-01	Nuevos derivados de oxazolidinonas como antibacterianos.
NO20065075L (no)	2006-11-16	Ikke-nukleosidbaserte revers-transkriptase-inhibitorer.
MXPA04006041A (es)	2004-09-27	Antivirales de piridoquinoxalina.
GEP20084437B (en)	2008-07-25	Novel lincomycin derivatives possessing antimicrobial activity
CA2437785A1 (en)	2002-10-10	Hiv inhibiting pyrazinone derivatives
MXPA04005809A (es)	2004-09-13	Inhibidores de proteinas quinasas.
NO20044550L (no)	2005-01-28	Heterotrisyklyl 6-alkaliden-penemer som beta-laktamaseinhibitorer
MXPA05010783A (es)	2005-12-12	Derivados antimicrobianos de [3.1.0] biciclohexilfenil-oxazolidinona y analogos.
AU2002248531A1 (en)	2002-09-24	Pyrazolopyriadine derivatives
MY148529A (en)	2013-04-30	Formulations of quinolinones