ATE373502T1 - Carbostyril-derivative zur beschleunigten speichelabsonderung - Google Patents

Carbostyril-derivative zur beschleunigten speichelabsonderung

Info

Publication number: ATE373502T1
Authority: AT; Austria
Prior art keywords: carbostyril; saliva; accelerated; xerostomia; prophylaxis
Prior art date: 2003-07-30

Application number

AT04747458T

Other languages

English (en)

Inventor

Hisashi Nagamoto

Masayuki Kohashi

Hiroshi Oka

Original Assignee

Otsuka Pharma Co Ltd

Univ School St Marianna

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-07-30

Filing date

2004-07-07

Publication date

2007-10-15

2004-07-07 Application filed by Otsuka Pharma Co Ltd, Univ School St Marianna filed Critical Otsuka Pharma Co Ltd

2007-10-15 Application granted granted Critical

2007-10-15 Publication of ATE373502T1 publication Critical patent/ATE373502T1/de

Links

LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical class C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 title abstract 4
210000003296 saliva Anatomy 0.000 title 1
208000005946 Xerostomia Diseases 0.000 abstract 3
206010039424 Salivary hypersecretion Diseases 0.000 abstract 2
206010013781 dry mouth Diseases 0.000 abstract 2
239000008194 pharmaceutical composition Substances 0.000 abstract 2
238000011321 prophylaxis Methods 0.000 abstract 2
208000026451 salivation Diseases 0.000 abstract 2
238000011282 treatment Methods 0.000 abstract 2
239000004480 active ingredient Substances 0.000 abstract 1
-1 carbostyril compound Chemical class 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
238000006467 substitution reaction Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Quinoline Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Enzymes And Modification Thereof (AREA)

AT04747458T 2003-07-30 2004-07-07 Carbostyril-derivative zur beschleunigten speichelabsonderung ATE373502T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2003282691		2003-07-30
JP2004021808		2004-01-29

Publications (1)

Publication Number	Publication Date
ATE373502T1 true ATE373502T1 (de)	2007-10-15

Family

ID=34117911

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04747458T ATE373502T1 (de)	2003-07-30	2004-07-07	Carbostyril-derivative zur beschleunigten speichelabsonderung

Country Status (9)

Country	Link
US (1)	US7879877B2 (de)
EP (1)	EP1648563B1 (de)
JP (1)	JP4394686B2 (de)
KR (1)	KR100681360B1 (de)
CN (1)	CN1859948B (de)
AT (1)	ATE373502T1 (de)
DE (1)	DE602004009079T2 (de)
MY (1)	MY142739A (de)
WO (1)	WO2005011811A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1863466B1 (de)	2005-03-03	2017-08-09	Takasago International Corporation (USA)	Synergistische speichelflusskomponenten
CN101910116B (zh)	2008-01-18	2013-06-19	高砂香料工业株式会社	(2e，6z，8e)-n-异丁基-2，6，8-癸三烯酰胺(千日菊酰胺)的制备方法，以及包含该化合物的食品或饮料、香料或化妆品、或药物
US8741930B2 (en) *	2008-10-24	2014-06-03	Bridge Pharma, Inc.	Treating xerophthalmia with norketotifen
US9597278B2 (en)	2008-11-13	2017-03-21	David A. Hamlin	Compositions and methods for alleviating hyposalivation and for providing oral comfort
US9884082B2 (en)	2008-11-13	2018-02-06	David A. Hamlin	Compositions and methods for alleviating hyposalivation and for providing oral comfort
US8765787B2 (en) *	2008-11-21	2014-07-01	Bridge Pharma, Inc.	Methods of treatment of xerophthalmia with self-preserving ocular formulations of norketotifen
CN103476753B (zh)	2011-02-25	2015-12-09	诺弗米克斯有限公司	新的瑞巴派特复合物和共晶体
BR112013024034A2 (pt)	2011-03-24	2016-12-13	Otsuka Pharma Co Ltd	composição farmacêutica para tratamento de doença na cavidade oral compreendendo rebamipida
JP6710040B2 (ja) *	2015-11-06	2020-06-17	江崎グリコ株式会社	唾液分泌促進剤及び口腔用組成物
KR102190019B1 (ko) *	2018-10-23	2020-12-15	삼진제약주식회사	쇼그렌 증후군 예방 또는 치료용 조성물
ES3062133T3 (en)	2020-02-18	2026-04-08	Sunstar Americas Inc	Oral care composition
EP4001434B1 (de) *	2020-11-18	2025-07-02	Korea Institute of Science and Technology	Speichelbiomarker zur diagnose von xerostomie und seine verwendung

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4322425A (en) *	1980-03-14	1982-03-30	Otsuka Pharmaceutical Co., Ltd.	Compositions for treating glaucoma
FI80022C (fi)	1982-07-05	1990-04-10	Otsuka Pharma Co Ltd	Foerfarande foer framstaellning av ett nytt, terapeutiskt anvaendbart karbostyrilderivat.
JP2812998B2 (ja)	1989-08-14	1998-10-22	大塚製薬株式会社	胃炎治療剤
DE69207560T2 (de)	1991-06-07	1996-06-27	Otsuka Pharma Co Ltd	Antidiabetikum
TW227558B (de) *	1992-05-14	1994-08-01	Otsuka Pharma Co Ltd
JP2872546B2 (ja)	1992-11-26	1999-03-17	大塚製薬株式会社	腸粘膜障害保護剤
WO1994021612A1 (en)	1993-03-18	1994-09-29	Otsuka Pharmaceutical Co., Ltd.	Carbostyril derivatives as matrix metalloproteinases inhibitors
JP2839827B2 (ja)	1993-10-05	1998-12-16	大塚製薬株式会社	ウレアーゼ阻害剤
CA2150546C (en)	1993-10-21	2004-11-09	Takahide Matsuda	Agent for inhibiting production of interleukin-8
KR970704439A (ko)	1994-08-10	1997-09-06	오쓰카 아키히코	눈의 염증 및/또는 상처의 예방 및 치료 방법(Method of preventing and treating ophthalmic inflammation and/or wound)
JPH0971532A (ja)	1995-09-06	1997-03-18	Otsuka Pharmaceut Co Ltd	発癌抑制剤
AR004214A1 (es)	1995-10-12	1998-11-04	Otsuka Pharma Co Ltd	Una preparación de gotas oftálmicas para la cura de enfermedades oftálmicas
WO1998026769A1 (en)	1996-12-16	1998-06-25	Otsuka Pharmaceutical Co., Ltd.	Adp-ribosyltransferase inhibitor
JPH11228413A (ja)	1998-02-20	1999-08-24	Otsuka Pharmaceut Co Ltd	Ｎａｄアーゼ阻害剤

2004
- 2004-07-07 AT AT04747458T patent/ATE373502T1/de not_active IP Right Cessation
- 2004-07-07 EP EP04747458A patent/EP1648563B1/de not_active Expired - Lifetime
- 2004-07-07 JP JP2006521775A patent/JP4394686B2/ja not_active Expired - Fee Related
- 2004-07-07 KR KR1020067001933A patent/KR100681360B1/ko not_active Expired - Fee Related
- 2004-07-07 CN CN2004800279758A patent/CN1859948B/zh not_active Expired - Fee Related
- 2004-07-07 WO PCT/JP2004/009992 patent/WO2005011811A1/en not_active Ceased
- 2004-07-07 US US10/566,214 patent/US7879877B2/en not_active Expired - Fee Related
- 2004-07-07 DE DE602004009079T patent/DE602004009079T2/de not_active Expired - Lifetime
- 2004-07-24 MY MYPI20042986A patent/MY142739A/en unknown

Also Published As

Publication number	Publication date
DE602004009079D1 (de)	2007-10-31
EP1648563B1 (de)	2007-09-19
DE602004009079T2 (de)	2008-06-19
JP4394686B2 (ja)	2010-01-06
US20070112026A1 (en)	2007-05-17
MY142739A (en)	2010-12-31
WO2005011811A1 (en)	2005-02-10
KR20060037408A (ko)	2006-05-03
US7879877B2 (en)	2011-02-01
CN1859948A (zh)	2006-11-08
KR100681360B1 (ko)	2007-02-12
JP2006528662A (ja)	2006-12-21
CN1859948B (zh)	2010-05-26
EP1648563A1 (de)	2006-04-26
HK1097474A1 (zh)	2007-06-29

Legal Events

Date	Code	Title	Description
2008-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

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NO20052739L (no)	2005-08-19	CCR5-antagonister som medikamenter
UA94901C2 (ru)	2011-06-25	Антибактериальные производные пиперидина
EE200300403A (et)	2003-12-15	N-asendatud mittearomaatne heterotsükliline ühend, seda sisaldav ravimkompositsioon ning ühendi kasutamine ravimina
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BR0208741A (pt)	2004-06-22	Derivados de piperidina
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NO20040881L (no)	2004-04-19	Orale antidiabetes midler.
SE0101932D0 (sv)	2001-05-31	Pharmaceutical combinations
DE602004008959D1 (de)	2007-10-25	Benzoäbüä1,4üdioxepinderivate
ES2186550A1 (es)	2003-05-01	Nuevos derivados de oxazolidinonas como antibacterianos.
DE602004009079D1 (de)	2007-10-31	Carbostyril-derivative zur beschleunigten speichelabsonderung
NO20065075L (no)	2006-11-16	Ikke-nukleosidbaserte revers-transkriptase-inhibitorer.
MXPA04006041A (es)	2004-09-27	Antivirales de piridoquinoxalina.
GEP20084437B (en)	2008-07-25	Novel lincomycin derivatives possessing antimicrobial activity
CA2437785A1 (en)	2002-10-10	Hiv inhibiting pyrazinone derivatives
MXPA04005809A (es)	2004-09-13	Inhibidores de proteinas quinasas.
NO20044550L (no)	2005-01-28	Heterotrisyklyl 6-alkaliden-penemer som beta-laktamaseinhibitorer
MXPA05010783A (es)	2005-12-12	Derivados antimicrobianos de [3.1.0] biciclohexilfenil-oxazolidinona y analogos.
AU2002248531A1 (en)	2002-09-24	Pyrazolopyriadine derivatives
TW200730176A (en)	2007-08-16	Formulations of quinolinones