ATE373715T1 - Isoprenoid biosynthese - Google Patents

Isoprenoid biosynthese

Info

Publication number
ATE373715T1
ATE373715T1 AT00949452T AT00949452T ATE373715T1 AT E373715 T1 ATE373715 T1 AT E373715T1 AT 00949452 T AT00949452 T AT 00949452T AT 00949452 T AT00949452 T AT 00949452T AT E373715 T1 ATE373715 T1 AT E373715T1
Authority
AT
Austria
Prior art keywords
inhibitors
relates
well
present
plant
Prior art date
Application number
AT00949452T
Other languages
English (en)
Inventor
Adelbert Bacher
Meinhart H Zenk
Wolfgang Eisenreich
Monika Fellermeier
Markus Fischer
Stefan Hecht
Stefan Herz
Klaus Kis
Holger Luettgen
Felix Rohdich
Silvia Sagner
Christoph Schuhr
Juraithip Wungsintaweekul
Original Assignee
Adelbert Bacher
Meinhart H Zenk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10020996A external-priority patent/DE10020996A1/de
Application filed by Adelbert Bacher, Meinhart H Zenk filed Critical Adelbert Bacher
Application granted granted Critical
Publication of ATE373715T1 publication Critical patent/ATE373715T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1229—Phosphotransferases with a phosphate group as acceptor (2.7.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AT00949452T 1999-08-04 2000-08-03 Isoprenoid biosynthese ATE373715T1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE19936663 1999-08-04
DE19945175 1999-09-21
DE19945174 1999-09-21
DE19948887 1999-10-11
DE19953309 1999-11-05
DE10020996A DE10020996A1 (de) 1999-08-04 2000-04-28 Isoprenoidbiosynthese

Publications (1)

Publication Number Publication Date
ATE373715T1 true ATE373715T1 (de) 2007-10-15

Family

ID=27544993

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00949452T ATE373715T1 (de) 1999-08-04 2000-08-03 Isoprenoid biosynthese

Country Status (6)

Country Link
US (2) US7122331B1 (de)
EP (1) EP1198575B1 (de)
AT (1) ATE373715T1 (de)
AU (1) AU6280300A (de)
DE (1) DE60036477T2 (de)
WO (1) WO2001011055A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10027821A1 (de) 2000-06-05 2001-12-06 Adelbert Bacher Der Mevalonat-unabhängige Isoprenoidbiosyntheseweg
US6660507B2 (en) 2000-09-01 2003-12-09 E. I. Du Pont De Nemours And Company Genes involved in isoprenoid compound production
US7736881B2 (en) 2000-10-13 2010-06-15 University Of Utah Research Foundation Antibacterial and herbicidal compounds and system for screening the same
DE10201458A1 (de) * 2001-04-11 2002-10-17 Adelbert Bacher Intermediate und Enzyme des Mevalonat-unabhängigen Isoprenoidbiosyntheseweg
CN101827936B (zh) * 2007-08-20 2014-12-10 肿瘤疗法科学股份有限公司 Cdh3肽以及含有cdh3肽的药剂
US8048654B2 (en) 2010-06-09 2011-11-01 Joule Unlimited Technologies, Inc. Methods and compositions for the recombinant biosynthesis of fatty acids and esters
EP2285948B1 (de) 2008-03-03 2014-01-08 Joule Unlimited Technologies, Inc. Konstruierte co2 fixierende mikroorganismen, die interessierende produkte auf kohlenstoffbasis produzieren
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same
ES2560281T3 (es) 2008-10-17 2016-02-18 Joule Unlimited Technologies, Inc. Producción de etanol por microorganismos
US20110020867A1 (en) * 2009-07-20 2011-01-27 Joule Unlimited, Inc. Constructs And Methods For Efficient Transformation Of Micro-Organisms For Production Of Carbon-Based Products Of Interest
CN105671108A (zh) 2010-06-02 2016-06-15 沃维公司 甜菊糖苷的重组生产
ES2372942B1 (es) * 2010-07-14 2012-12-04 Universidad De Cantabria Nueva enzima para la biosíntesis de isoprenoides.
CN108396044A (zh) 2011-08-08 2018-08-14 埃沃尔瓦公司 甜菊醇糖苷类的重组生产
US9808031B2 (en) 2012-10-25 2017-11-07 Run Them Sweet Llc Systems and methods to estimate nutritional needs of human and other patients
SG11201505597SA (en) 2013-02-06 2015-08-28 Evolva Sa Methods for improved production of rebaudioside d and rebaudioside m
CA2900882A1 (en) 2013-02-11 2014-08-14 Evolva Sa Efficient production of steviol glycosides in recombinants hosts
AU2015303294A1 (en) 2014-08-11 2017-02-02 Evolva Sa. Production of steviol glycosides in recombinant hosts
AU2015314251A1 (en) 2014-09-09 2017-03-16 Evolva Sa Production of steviol glycosides in recombinant hosts
SG11201705606PA (en) 2015-01-30 2017-08-30 Evolva Sa Production of steviol glycosides in recombinant hosts
CA2979931A1 (en) 2015-03-16 2016-09-22 Dsm Ip Assets B.V. Udp-glycosyltransferases
AU2016307066A1 (en) 2015-08-07 2018-02-08 Evolva Sa Production of steviol glycosides in recombinant hosts
US10982249B2 (en) 2016-04-13 2021-04-20 Evolva Sa Production of steviol glycosides in recombinant hosts
WO2017198682A1 (en) 2016-05-16 2017-11-23 Evolva Sa Production of steviol glycosides in recombinant hosts
US11396669B2 (en) 2016-11-07 2022-07-26 Evolva Sa Production of steviol glycosides in recombinant hosts
CN113337546B (zh) * 2021-06-04 2023-09-12 上海启讯医药科技有限公司 一种(s)-1，2，4-丁三醇的制备方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0154204B1 (de) 1984-03-06 1994-01-12 Mgi Pharma, Inc. Herbizide Resistenz in Pflanzen
GB9315751D0 (en) 1993-07-30 1993-09-15 Zeneca Ltd Dna,dna constructs,cells and plants derived therefrom
US5885782A (en) * 1994-09-13 1999-03-23 Nce Pharmaceuticals, Inc. Synthetic antibiotics
US6107071A (en) 1996-09-24 2000-08-22 Smithkline Beecham Corporation Histidinol dehydrogenase
US5858367A (en) 1997-03-27 1999-01-12 Case Western Reserve University Methods for screening for antimicrobials utilizing AarC and compositions thereof
EP1007626A4 (de) 1997-09-02 2004-08-04 Univ Washington Nuklein- und aminosäurensequenzen einer neuen transketolase von mentha piperita
DE19752700A1 (de) 1997-11-28 1999-06-02 Hoechst Schering Agrevo Gmbh 1-Desoxy-D-xylulose-5-phosphat Synthase, Verfahren zur Identifizierung von Effektoren der 1-Desoxy-D-xylulose-5-phosphat Synthase und Effektoren der 1-Desoxy-D-xylulose-5-phosphat Synthase
EP1071959A2 (de) 1998-04-14 2001-01-31 Jomaa Hassan Identifizierung chemischer wirkstoffe zur hemmung des 1-desoxy-d-xylulose-5-phosphat-biosynthesewegs in parasiten
WO1999058649A1 (en) 1998-05-13 1999-11-18 University Of Maryland Methods of modifying the production of isopentenyl pyrophosphate, dimethylallyl pyrophosphate and/or isoprenoids
AP2001002104A0 (en) 1998-09-22 2001-03-31 Jomaa Pharmaka Gmbh Genes of the 1-desoxy-d-xylulose biosynthetic pathway.
JP2002532101A (ja) 1998-12-14 2002-10-02 バッハー，アーデルバート テルペノイド類生合成阻害剤のためのスクリーニング
MXPA01011894A (es) 1999-05-21 2002-06-21 Jomaa Pharmaka Gmbh Uso de genes de las trayectorias biosinteticas de fosfato de desoxi-d-xilulosa para alterar la concentracion de isoprenoides.
DE10021688A1 (de) 2000-05-05 2001-11-15 Hassan Jomaa Gene des 1-Desoxy-D-xylulose-Biosynthesewegs
DE10027821A1 (de) 2000-06-05 2001-12-06 Adelbert Bacher Der Mevalonat-unabhängige Isoprenoidbiosyntheseweg
AR030124A1 (es) 2000-08-07 2003-08-13 Monsanto Technology Llc Genes de la via del fosfato de metil-d-eritritol
DE10201458A1 (de) 2001-04-11 2002-10-17 Adelbert Bacher Intermediate und Enzyme des Mevalonat-unabhängigen Isoprenoidbiosyntheseweg
ATE371729T1 (de) 2001-05-15 2007-09-15 Adelbert Bacher Kristallstruktur der 2c-methyl-d-erythritol-2,4- cyclodiphosphat-synthase
US20030073134A1 (en) 2001-06-18 2003-04-17 Louie Gordon V. Crystals and structures of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase MECPS

Also Published As

Publication number Publication date
EP1198575A1 (de) 2002-04-24
DE60036477D1 (en) 2007-10-31
AU6280300A (en) 2001-03-05
EP1198575B1 (de) 2007-09-19
US7534742B2 (en) 2009-05-19
US7122331B1 (en) 2006-10-17
US20070015216A1 (en) 2007-01-18
DE60036477T2 (de) 2008-06-12
WO2001011055A1 (en) 2001-02-15

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