ATE373715T1 - Isoprenoid biosynthese - Google Patents

Isoprenoid biosynthese

Info

Publication number
ATE373715T1
ATE373715T1 AT00949452T AT00949452T ATE373715T1 AT E373715 T1 ATE373715 T1 AT E373715T1 AT 00949452 T AT00949452 T AT 00949452T AT 00949452 T AT00949452 T AT 00949452T AT E373715 T1 ATE373715 T1 AT E373715T1
Authority
AT
Austria
Prior art keywords
inhibitors
relates
well
present
plant
Prior art date
Application number
AT00949452T
Other languages
English (en)
Inventor
Adelbert Bacher
Meinhart H Zenk
Wolfgang Eisenreich
Monika Fellermeier
Markus Fischer
Stefan Hecht
Stefan Herz
Klaus Kis
Holger Luettgen
Felix Rohdich
Silvia Sagner
Christoph Schuhr
Juraithip Wungsintaweekul
Original Assignee
Adelbert Bacher
Meinhart H Zenk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10020996A external-priority patent/DE10020996A1/de
Application filed by Adelbert Bacher, Meinhart H Zenk filed Critical Adelbert Bacher
Application granted granted Critical
Publication of ATE373715T1 publication Critical patent/ATE373715T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1229—Phosphotransferases with a phosphate group as acceptor (2.7.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT00949452T 1999-08-04 2000-08-03 Isoprenoid biosynthese ATE373715T1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE19936663 1999-08-04
DE19945174 1999-09-21
DE19945175 1999-09-21
DE19948887 1999-10-11
DE19953309 1999-11-05
DE10020996A DE10020996A1 (de) 1999-08-04 2000-04-28 Isoprenoidbiosynthese

Publications (1)

Publication Number Publication Date
ATE373715T1 true ATE373715T1 (de) 2007-10-15

Family

ID=27544993

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00949452T ATE373715T1 (de) 1999-08-04 2000-08-03 Isoprenoid biosynthese

Country Status (6)

Country Link
US (2) US7122331B1 (de)
EP (1) EP1198575B1 (de)
AT (1) ATE373715T1 (de)
AU (1) AU6280300A (de)
DE (1) DE60036477T2 (de)
WO (1) WO2001011055A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10027821A1 (de) 2000-06-05 2001-12-06 Adelbert Bacher Der Mevalonat-unabhängige Isoprenoidbiosyntheseweg
US6660507B2 (en) 2000-09-01 2003-12-09 E. I. Du Pont De Nemours And Company Genes involved in isoprenoid compound production
US7736881B2 (en) 2000-10-13 2010-06-15 University Of Utah Research Foundation Antibacterial and herbicidal compounds and system for screening the same
DE10201458A1 (de) * 2001-04-11 2002-10-17 Adelbert Bacher Intermediate und Enzyme des Mevalonat-unabhängigen Isoprenoidbiosyntheseweg
US8455444B2 (en) * 2007-08-20 2013-06-04 Oncotherapy Science, Inc. CDH3 peptide and medicinal agent comprising the same
US8048654B2 (en) 2010-06-09 2011-11-01 Joule Unlimited Technologies, Inc. Methods and compositions for the recombinant biosynthesis of fatty acids and esters
EP2285948B1 (de) * 2008-03-03 2014-01-08 Joule Unlimited Technologies, Inc. Konstruierte co2 fixierende mikroorganismen, die interessierende produkte auf kohlenstoffbasis produzieren
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same
CN103725717A (zh) 2008-10-17 2014-04-16 焦耳无限科技公司 微生物的乙醇生产
US20110020867A1 (en) * 2009-07-20 2011-01-27 Joule Unlimited, Inc. Constructs And Methods For Efficient Transformation Of Micro-Organisms For Production Of Carbon-Based Products Of Interest
EP2575432B1 (de) 2010-06-02 2019-08-14 Evolva, Inc. Rekombinante herstellung von steviol-glycosiden
ES2372942B1 (es) * 2010-07-14 2012-12-04 Universidad De Cantabria Nueva enzima para la biosíntesis de isoprenoides.
AU2012294452C1 (en) 2011-08-08 2017-11-30 Danstar Ferment Ag Recombinant production of steviol glycosides
US9808031B2 (en) 2012-10-25 2017-11-07 Run Them Sweet Llc Systems and methods to estimate nutritional needs of human and other patients
WO2014122227A2 (en) 2013-02-06 2014-08-14 Evolva Sa Methods for improved production of rebaudioside d and rebaudioside m
BR112015019160A2 (pt) 2013-02-11 2017-08-22 Dalgaard Mikkelsen Michael Produção de glicosídeos de esteviol em hospedeiros recombinantes
CN114410493A (zh) 2014-08-11 2022-04-29 埃沃尔瓦公司 在重组宿主中生产甜菊醇糖苷
KR20170052647A (ko) 2014-09-09 2017-05-12 에볼바 에스아 재조합 숙주에서 스테비올 글리코시드의 생성
AU2016211124B2 (en) 2015-01-30 2022-04-14 Danstar Ferment Ag Production of steviol glycosides in recombinant hosts
EP3271457B1 (de) 2015-03-16 2021-01-20 DSM IP Assets B.V. Udp-glycosyltransferasen
EP3332018B1 (de) 2015-08-07 2022-07-27 Evolva SA Erzeugung von steviolglycosiden in rekombinanten wirten
KR20180132696A (ko) 2016-04-13 2018-12-12 에볼바 에스아 재조합 숙주에서의 스테비올 글리코사이드의 생산
US10815514B2 (en) 2016-05-16 2020-10-27 Evolva Sa Production of steviol glycosides in recombinant hosts
WO2018083338A1 (en) 2016-11-07 2018-05-11 Evolva Sa Production of steviol glycosides in recombinant hosts
CN113337546B (zh) * 2021-06-04 2023-09-12 上海启讯医药科技有限公司 一种(s)-1，2，4-丁三醇的制备方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE100141T1 (de) 1984-03-06 1994-01-15 Mgi Pharma Inc Herbizide resistenz in pflanzen.
GB9315751D0 (en) * 1993-07-30 1993-09-15 Zeneca Ltd Dna,dna constructs,cells and plants derived therefrom
US5885782A (en) * 1994-09-13 1999-03-23 Nce Pharmaceuticals, Inc. Synthetic antibiotics
US6107071A (en) * 1996-09-24 2000-08-22 Smithkline Beecham Corporation Histidinol dehydrogenase
US5858367A (en) 1997-03-27 1999-01-12 Case Western Reserve University Methods for screening for antimicrobials utilizing AarC and compositions thereof
AU746684B2 (en) 1997-09-02 2002-05-02 Washington State University Research Foundation Nucleic and amino acid sequences for a novel transketolase from $i (Mentha Piperita)
DE19752700A1 (de) 1997-11-28 1999-06-02 Hoechst Schering Agrevo Gmbh 1-Desoxy-D-xylulose-5-phosphat Synthase, Verfahren zur Identifizierung von Effektoren der 1-Desoxy-D-xylulose-5-phosphat Synthase und Effektoren der 1-Desoxy-D-xylulose-5-phosphat Synthase
AU753169B2 (en) 1998-04-14 2002-10-10 Bioagency Ag Method for identifying chemical active agents and active agents for inhibiting the 1-desoxy-D-xylulose-5-phosphate biosynthetic pathway
EP1078045A1 (de) 1998-05-13 2001-02-28 University Of Maryland College Park Methoden zur modifikation der herstellung von isopenyl-pyrophosphat, dimethylallyl-pyrophosphat und/oder isoprenoide
SK3922001A3 (en) 1998-09-22 2001-09-11 Jomaa Pharmaka Gmbh Genes of the 1-desoxy-d-xylulose biosynthetic pathway
EP1141379A1 (de) 1998-12-14 2001-10-10 Adelbert Bacher Screening für inhibitoren von terpenoiden-biosynthese
TR200103326T2 (tr) 1999-05-21 2002-04-22 Jomaa Pharmaka Gmbh İsoprenoidin konsantrasyonunu değiştirmek için deoksi-D-ksiluloz fosfat biyosentetik yoluna ait genlerin kullanımı
DE10021688A1 (de) 2000-05-05 2001-11-15 Hassan Jomaa Gene des 1-Desoxy-D-xylulose-Biosynthesewegs
DE10027821A1 (de) 2000-06-05 2001-12-06 Adelbert Bacher Der Mevalonat-unabhängige Isoprenoidbiosyntheseweg
US6841717B2 (en) 2000-08-07 2005-01-11 Monsanto Technology, L.L.C. Methyl-D-erythritol phosphate pathway genes
DE10201458A1 (de) 2001-04-11 2002-10-17 Adelbert Bacher Intermediate und Enzyme des Mevalonat-unabhängigen Isoprenoidbiosyntheseweg
WO2002092800A2 (en) 2001-05-15 2002-11-21 Max-Planck-Gesellschaft Crystal structure of 2c-methyl-d-erythritol 2,4-cyclodiphosphate synthase
WO2002102991A2 (en) 2001-06-18 2002-12-27 Structural Genomix Crystals and structure of 2c-methyl-d-erythritol 2,4-cyclodiphosphate synthase mecps

Also Published As

Publication number Publication date
US7122331B1 (en) 2006-10-17
US20070015216A1 (en) 2007-01-18
AU6280300A (en) 2001-03-05
WO2001011055A1 (en) 2001-02-15
EP1198575A1 (de) 2002-04-24
US7534742B2 (en) 2009-05-19
EP1198575B1 (de) 2007-09-19
DE60036477T2 (de) 2008-06-12
DE60036477D1 (en) 2007-10-31

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